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Items: 20


Optically Robust and Biocompatible Mechanosensitive Upconverting Nanoparticles.

Lay A, Sheppard OH, Siefe C, McLellan CA, Mehlenbacher RD, Fischer S, Goodman MB, Dionne JA.

ACS Cent Sci. 2019 Jul 24;5(7):1211-1222. doi: 10.1021/acscentsci.9b00300. Epub 2019 Jul 9.


Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

Basheer F, Giotopoulos G, Meduri E, Yun H, Mazan M, Sasca D, Gallipoli P, Marando L, Gozdecka M, Asby R, Sheppard O, Dudek M, Bullinger L, Döhner H, Dillon R, Freeman S, Ottmann O, Burnett A, Russell N, Papaemmanuil E, Hills R, Campbell P, Vassiliou GS, Huntly BJP.

J Exp Med. 2019 Apr 1;216(4):966-981. doi: 10.1084/jem.20181276. Epub 2019 Mar 19.


Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.

Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, Tosh JL, Siganporia C, Whittaker HT, Stewart F, Szaruga M; London Down syndrome consortium, Murphy MP, Blennow K, de Strooper B, Zetterberg H, Bannerman D, Holtzman DM, Tybulewicz VLJ, Fisher EMC; LonDownS Consortium.

Brain. 2018 Aug 1;141(8):2457-2474. doi: 10.1093/brain/awy159. Erratum in: Brain. 2019 Jun 1;142(6):e25.


Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.

Horton SJ, Giotopoulos G, Yun H, Vohra S, Sheppard O, Bashford-Rogers R, Rashid M, Clipson A, Chan WI, Sasca D, Yiangou L, Osaki H, Basheer F, Gallipoli P, Burrows N, Erdem A, Sybirna A, Foerster S, Zhao W, Sustic T, Petrunkina Harrison A, Laurenti E, Okosun J, Hodson D, Wright P, Smith KG, Maxwell P, Fitzgibbon J, Du MQ, Adams DJ, Huntly BJP.

Nat Cell Biol. 2017 Sep;19(9):1093-1104. doi: 10.1038/ncb3597. Epub 2017 Aug 21.


Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, Simpson TI, Tybulewicz VL, Wyllie DJ, Fisher EM, Lowell S, Chandran S, Hardingham GE.

Elife. 2016 Oct 1;5. pii: e20337. doi: 10.7554/eLife.20337.


Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome.

Gribble SM, Wiseman FK, Clayton S, Prigmore E, Langley E, Yang F, Maguire S, Fu B, Rajan D, Sheppard O, Scott C, Hauser H, Stephens PJ, Stebbings LA, Ng BL, Fitzgerald T, Quail MA, Banerjee R, Rothkamm K, Tybulewicz VL, Fisher EM, Carter NP.

PLoS One. 2013 Apr 15;8(4):e60482. doi: 10.1371/journal.pone.0060482. Print 2013.


Mouse models of aneuploidy.

Sheppard O, Wiseman FK, Ruparelia A, Tybulewicz VL, Fisher EM.

ScientificWorldJournal. 2012;2012:214078. doi: 10.1100/2012/214078. Epub 2012 Jan 3. Review.


Altered regulation of tau phosphorylation in a mouse model of down syndrome aging.

Sheppard O, Plattner F, Rubin A, Slender A, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM, Wiseman FK.

Neurobiol Aging. 2012 Apr;33(4):828.e31-44. doi: 10.1016/j.neurobiolaging.2011.06.025. Epub 2011 Aug 16.


Generation of a panel of antibodies against proteins encoded on human chromosome 21.

Wiseman FK, Sheppard O, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM.

J Negat Results Biomed. 2010 Aug 20;9:7. doi: 10.1186/1477-5751-9-7.


Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21.

Ruparelia A, Wiseman F, Sheppard O, Tybulewicz VL, Fisher EM.

J Biomed Res. 2010 Mar;24(2):87-99. doi: 10.1016/S1674-8301(10)60016-4.


Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F.

Zhang L, Sheppard OR, Shah AM, Brewer AC.

Free Radic Biol Med. 2008 Sep 1;45(5):679-85. doi: 10.1016/j.freeradbiomed.2008.05.019. Epub 2008 May 29.


(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons.

Schroeter H, Bahia P, Spencer JP, Sheppard O, Rattray M, Cadenas E, Rice-Evans C, Williams RJ.

J Neurochem. 2007 Jun;101(6):1596-606. Epub 2007 Feb 7.


Structure of ionic liquid-benzene mixtures.

Deetlefs M, Hardacre C, Nieuwenhuyzen M, Sheppard O, Soper AK.

J Phys Chem B. 2005 Feb 3;109(4):1593-8.


Liquid structure of the ionic liquid 1,3-dimethylimidazolium bis[(trifluoromethyl)sulfonyl]amide.

Deetlefs M, Hardacre C, Nieuwenhuyzen M, Padua AA, Sheppard O, Soper AK.

J Phys Chem B. 2006 Jun 22;110(24):12055-61.


Liquid clathrate formation in ionic liquid-aromatic mixtures.

Holbrey JD, Reichert WM, Nieuwenhuyzen M, Sheppard O, Hardacre C, Rogers RD.

Chem Commun (Camb). 2003 Feb 21;(4):476-7.


"Primed" human neutrophils on a standard peripheral blood smear.

Sheppard oR, Moore EE, Ryder J, Harken AH, Rezende-Neto JB, Banerjee A, Silliman CC.

J Am Coll Surg. 2002 Nov;195(5):731. No abstract available.


More from Burma.

Sheppard OH.

J Natl Med Assoc. 1951 Sep;43(5):349-50. No abstract available.


Rangoon to Mandalay.

Sheppard OH.

J Natl Med Assoc. 1951 Mar;43(2):141. No abstract available.



Sheppard OE.

Science. 1934 Apr 13;79(2050):342-3. No abstract available.


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