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Items: 1 to 50 of 720

1.

Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases.

Le Mauff F, Bamford NC, Alnabelseya N, Zhang Y, Baker P, Robinson H, Codée JDC, Howell PL, Sheppard DC.

J Biol Chem. 2019 Jun 5. pii: jbc.RA119.008511. doi: 10.1074/jbc.RA119.008511. [Epub ahead of print]

2.

The role of Aspergillus fumigatus polysaccharides in host-pathogen interactions.

Zacharias CA, Sheppard DC.

Curr Opin Microbiol. 2019 May 20;52:20-26. doi: 10.1016/j.mib.2019.04.006. [Epub ahead of print] Review.

PMID:
31121411
3.

Where have I heard that before? A validity study of source memory indices from the California Verbal Learning Test - Second edition.

Babicz MA, Sheppard DP, Morgan EE, Paul Woods S.

Clin Neuropsychol. 2019 May 14:1-20. doi: 10.1080/13854046.2019.1613559. [Epub ahead of print]

PMID:
31084399
4.

Preferred Formation of Heteromeric Channels between Coexpressed SK1 and IKCa Channel Subunits Provides a Unique Pharmacological Profile of Ca2+-Activated Potassium Channels.

Higham J, Sahu G, Wazen RM, Colarusso P, Gregorie A, Harvey BSJ, Goudswaard L, Varley G, Sheppard DN, Turner RW, Marrion NV.

Mol Pharmacol. 2019 Jul;96(1):115-126. doi: 10.1124/mol.118.115634. Epub 2019 May 2.

PMID:
31048549
5.

Do importance instructions improve time-based prospective remembering in autism spectrum conditions?

Altgassen M, Sheppard DP, Hendriks MPH.

Res Dev Disabil. 2019 Jul;90:1-13. doi: 10.1016/j.ridd.2019.04.008. Epub 2019 Apr 20.

PMID:
31015072
6.

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR.

Bose SJ, Bijvelds MJC, Wang Y, Liu J, Cai Z, Bot AGM, de Jonge HR, Sheppard DN.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L71-L86. doi: 10.1152/ajplung.00034.2019. Epub 2019 Apr 10.

7.

Triazole Antifungal Susceptibility Patterns among Aspergillus Species in Québec, Canada.

Cheng MP, Lawandi A, Lee TC, Dufresne PJ, Seidel D, Verweij PE, Cornely OA, Sheppard DC.

J Clin Microbiol. 2019 May 24;57(6). pii: e00404-19. doi: 10.1128/JCM.00404-19. Print 2019 Jun. No abstract available.

PMID:
30918044
8.

Decomposition pathway of KAlH4 altered by the addition of Al2S3.

Sheppard DA, Jepsen LH, Rowles MR, Paskevicius M, Jensen TR, Buckley CE.

Dalton Trans. 2019 Apr 9;48(15):5048-5057. doi: 10.1039/c9dt00457b.

PMID:
30916691
9.

Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport.

Spooner MJ, Li H, Marques I, Costa PMR, Wu X, Howe ENW, Busschaert N, Moore SJ, Light ME, Sheppard DN, Félix V, Gale PA.

Chem Sci. 2018 Dec 14;10(7):1976-1985. doi: 10.1039/c8sc05155k. eCollection 2019 Feb 21.

10.

The mitochondrial thiamine pyrophosphate transporter TptA promotes adaptation to low iron conditions and virulence in fungal pathogen Aspergillus fumigatus.

Huang J, Ma Z, Zhong G, Sheppard DC, Lu L, Zhang S.

Virulence. 2019 Dec;10(1):234-247. doi: 10.1080/21505594.2019.1596505.

11.

Pore-forming small molecules offer a promising way to tackle cystic fibrosis.

Sheppard DN, Davis AP.

Nature. 2019 Mar;567(7748):315-317. doi: 10.1038/d41586-019-00781-y. No abstract available.

PMID:
30880331
12.

Circulating (1→3)-β-D-Glucan is associated with immune activation during HIV infection.

Mehraj V, Ramendra R, Isnard S, Dupuy FP, Ponte R, Chen J, Kema I, Jenabian MA, Costiniuk C, Lebouché B, Thomas R, Coté P, Leblanc R, Baril JG, Durand M, Chartrand-Lefebvre C, Tremblay C, Ancuta P, Bernard NF, Sheppard DC, Routy JP; Montreal Primary HIV-infection Study and Canadian HIV and Aging Cohort Study Groups.

Clin Infect Dis. 2019 Mar 16. pii: ciz212. doi: 10.1093/cid/ciz212. [Epub ahead of print]

PMID:
30877304
13.

Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction.

Arnold TD, Lizama CO, Cautivo KM, Santander N, Lin L, Qiu H, Huang EJ, Liu C, Mukouyama YS, Reichardt LF, Zovein AC, Sheppard D.

J Exp Med. 2019 Apr 1;216(4):900-915. doi: 10.1084/jem.20181290. Epub 2019 Mar 7.

14.

α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.

Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza A, Quezada SA, Rosenblum MD, Krummel MF, Balmain A, Akhurst RJ.

J Immunother Cancer. 2019 Mar 4;7(1):62. doi: 10.1186/s40425-018-0493-9.

15.

Beyond tissue concentrations: antifungal penetration at the site of infection.

Zhao Y, Prideaux B, Baistrocchi S, Sheppard DC, Perlin DS.

Med Mycol. 2019 Apr 1;57(Supplement_2):S161-S167. doi: 10.1093/mmy/myy067. Review.

PMID:
30816968
16.

Clinical features and cause analysis of false positive results of Aspergillus galactomannan assay in pulmonary cryptococcosis patients.

Takazono T, Saijo T, Ashizawa N, Oshima K, Nishimura K, Tashiro M, Yamamoto K, Imamura Y, Miyazaki T, Yanagihara K, Mukae H, Izumikawa K, Sheppard DC.

Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):735-741. doi: 10.1007/s10096-019-03469-3. Epub 2019 Jan 25.

PMID:
30684164
17.

IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility.

Bulek K, Chen X, Parron V, Sundaram A, Herjan T, Ouyang S, Liu C, Majors A, Zepp J, Gao J, Dongre A, Bodaszewska-Lubas M, Echard A, Aronica M, Carman J, Garantziotis S, Sheppard D, Li X.

J Immunol. 2019 Mar 1;202(5):1540-1548. doi: 10.4049/jimmunol.1801025. Epub 2019 Jan 25.

18.

Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis.

Speth C, Rambach G, Lass-Flörl C, Howell PL, Sheppard DC.

Virulence. 2019 Jan 22:1-8. doi: 10.1080/21505594.2019.1568174. [Epub ahead of print]

PMID:
30667338
19.

β6 -integrin serves as a novel serum tumor marker for colorectal carcinoma.

Bengs S, Becker E, Busenhart P, Spalinger MR, Raselli T, Kasper S, Lang S, Atrott K, Mamie C, Vavricka SR, von Boehmer L, Knuth A, Tuomisto A, Mäkinen MJ, Hruz P, Turina M, Rickenbacher A, Petrowsky H, Weber A, Frei P, Halama M, Jenkins G, Sheppard D, Croner RS, Christoph J, Britzen-Laurent N, Naschberger E, Schellerer V, Stürzl M, Fried M, Rogler G, Scharl M.

Int J Cancer. 2019 Aug 1;145(3):678-685. doi: 10.1002/ijc.32137. Epub 2019 Jan 29.

PMID:
30653264
20.

Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung.

Thamsen M, Ghosh R, Auyeung VC, Brumwell A, Chapman HA, Backes BJ, Perara G, Maly DJ, Sheppard D, Papa FR.

PLoS One. 2019 Jan 9;14(1):e0209824. doi: 10.1371/journal.pone.0209824. eCollection 2019.

21.

Deacetylated microbial biofilm exopolysaccharides: It pays to be positive.

Ostapska H, Howell PL, Sheppard DC.

PLoS Pathog. 2018 Dec 27;14(12):e1007411. doi: 10.1371/journal.ppat.1007411. eCollection 2018 Dec. Review. No abstract available.

22.

Ensembl variation resources.

Hunt SE, McLaren W, Gil L, Thormann A, Schuilenburg H, Sheppard D, Parton A, Armean IM, Trevanion SJ, Flicek P, Cunningham F.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay119.

23.

Extrapyramidal motor signs in older adults with HIV disease: frequency, 1-year course, and associations with activities of daily living and quality of life.

Tierney SM, Woods SP, Sheppard D, Ellis RJ.

J Neurovirol. 2019 Apr;25(2):162-173. doi: 10.1007/s13365-018-0699-0. Epub 2018 Dec 10.

PMID:
30535869
24.

Medication Management Capacity and Its Neurocognitive Correlates in Huntington's Disease.

Sumida CA, Van Etten EJ, Lopez FV, Sheppard DP, Pirogovsky-Turk E, Corey-Bloom J, Filoteo JV, Woods SP, Gilbert PE, Schmitter-Edgecombe M.

Arch Clin Neuropsychol. 2018 Dec 5. doi: 10.1093/arclin/acy093. [Epub ahead of print]

PMID:
30517595
25.

Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration.

Greenhalgh SN, Matchett KP, Taylor RS, Huang K, Li JT, Saeteurn K, Donnelly MC, Simpson EEM, Pollack JL, Atakilit A, Simpson KJ, Maher JJ, Iredale JP, Sheppard D, Henderson NC.

Am J Pathol. 2019 Feb;189(2):258-271. doi: 10.1016/j.ajpath.2018.10.007. Epub 2018 Nov 16.

26.

Ensembl 2019.

Cunningham F, Achuthan P, Akanni W, Allen J, Amode MR, Armean IM, Bennett R, Bhai J, Billis K, Boddu S, Cummins C, Davidson C, Dodiya KJ, Gall A, Girón CG, Gil L, Grego T, Haggerty L, Haskell E, Hourlier T, Izuogu OG, Janacek SH, Juettemann T, Kay M, Laird MR, Lavidas I, Liu Z, Loveland JE, Marugán JC, Maurel T, McMahon AC, Moore B, Morales J, Mudge JM, Nuhn M, Ogeh D, Parker A, Parton A, Patricio M, Abdul Salam AI, Schmitt BM, Schuilenburg H, Sheppard D, Sparrow H, Stapleton E, Szuba M, Taylor K, Threadgold G, Thormann A, Vullo A, Walts B, Winterbottom A, Zadissa A, Chakiachvili M, Frankish A, Hunt SE, Kostadima M, Langridge N, Martin FJ, Muffato M, Perry E, Ruffier M, Staines DM, Trevanion SJ, Aken BL, Yates AD, Zerbino DR, Flicek P.

Nucleic Acids Res. 2019 Jan 8;47(D1):D745-D751. doi: 10.1093/nar/gky1113.

27.

Arhgef12 drives IL17A-induced airway contractility and airway hyperresponsiveness in mice.

Fong V, Hsu A, Wu E, Looney AP, Ganesan P, Ren X, Sheppard D, Wicher SA, Thompson MA, Britt RD Jr, Prakash YS, Bhattacharya M.

JCI Insight. 2018 Nov 2;3(21). pii: 123578. doi: 10.1172/jci.insight.123578.

28.

Frequency and Correlates of Subjective Cognitive Impairment in HIV Disease.

Sheppard DP, Woods SP, Massman PJ, Gilbert PE.

AIDS Behav. 2019 Mar;23(3):617-626. doi: 10.1007/s10461-018-2297-9.

PMID:
30311103
29.

Standardizing the evaluation of community-based conservation success.

Brichieri-Colombi TA, McPherson JM, Sheppard DJ, Mason JJ, Moehrenschlager A.

Ecol Appl. 2018 Dec;28(8):1963-1981. doi: 10.1002/eap.1788. Epub 2018 Sep 10.

PMID:
30199581
30.

Potentiation of the cystic fibrosis transmembrane conductance regulator Cl- channel by ivacaftor is temperature independent.

Wang Y, Cai Z, Gosling M, Sheppard DN.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L846-L857. doi: 10.1152/ajplung.00235.2018. Epub 2018 Aug 23.

PMID:
30136610
31.

N1303K: Leaving no stone unturned in the search for transformational therapeutics.

Noel S, Sermet-Gaudelus I, Sheppard DN.

J Cyst Fibros. 2018 Sep;17(5):555-557. doi: 10.1016/j.jcf.2018.07.009. Epub 2018 Aug 17. No abstract available.

PMID:
30126793
32.

Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators.

Han ST, Rab A, Pellicore MJ, Davis EF, McCague AF, Evans TA, Joynt AT, Lu Z, Cai Z, Raraigh KS, Hong JS, Sheppard DN, Sorscher EJ, Cutting GR.

JCI Insight. 2018 Jul 26;3(14). pii: 121159. doi: 10.1172/jci.insight.121159. eCollection 2018 Jul 26.

33.

Cell division cycle 7 kinase is a negative regulator of cell-mediated collagen degradation.

Podolsky MJ, Gupta D, Ha A, Ta R, Khalifeh-Soltani A, McKleroy W, Datta R, Sheppard D, Atabai K.

Am J Physiol Lung Cell Mol Physiol. 2018 Sep 1;315(3):L360-L370. doi: 10.1152/ajplung.00144.2018. Epub 2018 May 24.

PMID:
29792348
34.

Does intra-individual neurocognitive variability relate to neuroinvasive disease and quality of life in West Nile Virus?

Sheppard DP, Woods SP, Hasbun R, Salazar L, Nolan MS, Murray KO.

J Neurovirol. 2018 Aug;24(4):506-513. doi: 10.1007/s13365-018-0641-5. Epub 2018 Apr 25.

PMID:
29696579
35.

PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.

Little DJ, Pfoh R, Le Mauff F, Bamford NC, Notte C, Baker P, Guragain M, Robinson H, Pier GB, Nitz M, Deora R, Sheppard DC, Howell PL.

PLoS Pathog. 2018 Apr 23;14(4):e1006998. doi: 10.1371/journal.ppat.1006998. eCollection 2018 Apr.

36.

Big Data in Drug Discovery.

Brown N, Cambruzzi J, Cox PJ, Davies M, Dunbar J, Plumbley D, Sellwood MA, Sim A, Williams-Jones BI, Zwierzyna M, Sheppard DW.

Prog Med Chem. 2018;57(1):277-356. doi: 10.1016/bs.pmch.2017.12.003. Epub 2018 Feb 24. Review.

PMID:
29680150
37.

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline.

Ullmann AJ, Aguado JM, Arikan-Akdagli S, Denning DW, Groll AH, Lagrou K, Lass-Flörl C, Lewis RE, Munoz P, Verweij PE, Warris A, Ader F, Akova M, Arendrup MC, Barnes RA, Beigelman-Aubry C, Blot S, Bouza E, Brüggemann RJM, Buchheidt D, Cadranel J, Castagnola E, Chakrabarti A, Cuenca-Estrella M, Dimopoulos G, Fortun J, Gangneux JP, Garbino J, Heinz WJ, Herbrecht R, Heussel CP, Kibbler CC, Klimko N, Kullberg BJ, Lange C, Lehrnbecher T, Löffler J, Lortholary O, Maertens J, Marchetti O, Meis JF, Pagano L, Ribaud P, Richardson M, Roilides E, Ruhnke M, Sanguinetti M, Sheppard DC, Sinkó J, Skiada A, Vehreschild MJGT, Viscoli C, Cornely OA.

Clin Microbiol Infect. 2018 May;24 Suppl 1:e1-e38. doi: 10.1016/j.cmi.2018.01.002. Epub 2018 Mar 12.

38.

Five Alternative Myosin Converter Domains Influence Muscle Power, Stretch Activation, and Kinetics.

Glasheen BM, Ramanath S, Patel M, Sheppard D, Puthawala JT, Riley LA, Swank DM.

Biophys J. 2018 Mar 13;114(5):1142-1152. doi: 10.1016/j.bpj.2017.12.045.

39.

Prospective memory in autism: theory and literature review.

Sheppard DP, Bruineberg JP, Kretschmer-Trendowicz A, Altgassen M.

Clin Neuropsychol. 2018 Jul;32(5):748-782. doi: 10.1080/13854046.2018.1435823. Epub 2018 Mar 14.

PMID:
29536800
40.

Hoisted by their own petard: do microbial enzymes hold the solution to treating and preventing biofilm infections?

Snarr BD, Howell PL, Sheppard DC.

Future Microbiol. 2018 Mar;13:395-398. doi: 10.2217/fmb-2017-0243. Epub 2018 Feb 14. No abstract available.

PMID:
29441819
41.

Impaired spatial pattern separation performance in temporal lobe epilepsy is associated with visuospatial memory deficits and hippocampal volume loss.

Reyes A, Holden HM, Chang YA, Uttarwar VS, Sheppard DP, DeFord NE, DeJesus SY, Kansal L, Gilbert PE, McDonald CR.

Neuropsychologia. 2018 Mar;111:209-215. doi: 10.1016/j.neuropsychologia.2018.02.009. Epub 2018 Feb 8.

42.

Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection.

Shourian M, Ralph B, Angers I, Sheppard DC, Qureshi ST.

Front Immunol. 2018 Jan 19;8:1987. doi: 10.3389/fimmu.2017.01987. eCollection 2017.

43.

Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes.

Dias CM, Li H, Valkenier H, Karagiannidis LE, Gale PA, Sheppard DN, Davis AP.

Org Biomol Chem. 2018 Feb 14;16(7):1083-1087. doi: 10.1039/c7ob02787g.

PMID:
29376532
44.

The Interface between Fungal Biofilms and Innate Immunity.

Kernien JF, Snarr BD, Sheppard DC, Nett JE.

Front Immunol. 2018 Jan 10;8:1968. doi: 10.3389/fimmu.2017.01968. eCollection 2017. Review.

45.

Immune Recognition of Fungal Polysaccharides.

Snarr BD, Qureshi ST, Sheppard DC.

J Fungi (Basel). 2017 Aug 28;3(3). pii: E47. doi: 10.3390/jof3030047. Review.

46.

Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small molecule.

Liu J, Bihler H, Farinha CM, Awatade NT, Romão AM, Mercadante D, Cheng Y, Musisi I, Jantarajit W, Wang Y, Cai Z, Amaral MD, Mense M, Sheppard DN.

Br J Pharmacol. 2018 Apr;175(7):1017-1038. doi: 10.1111/bph.14141. Epub 2018 Feb 22.

47.

Extended Lagrangian Excited State Molecular Dynamics.

Bjorgaard JA, Sheppard D, Tretiak S, Niklasson AMN.

J Chem Theory Comput. 2018 Feb 13;14(2):799-806. doi: 10.1021/acs.jctc.7b00857. Epub 2018 Jan 31.

PMID:
29316401
48.

Thermodynamics and performance of the Mg-H-F system for thermochemical energy storage applications.

Tortoza MS, Humphries TD, Sheppard DA, Paskevicius M, Rowles MR, Sofianos MV, Aguey-Zinsou KF, Buckley CE.

Phys Chem Chem Phys. 2018 Jan 24;20(4):2274-2283. doi: 10.1039/c7cp07433f.

PMID:
29303173
49.

Editorial overview: Respiratory: Transformational therapies for cystic fibrosis.

Sheppard DN, Bear CE, de Jonge HR.

Curr Opin Pharmacol. 2017 Jun;34:viii-xi. doi: 10.1016/j.coph.2017.11.006. No abstract available.

PMID:
29221574
50.

Ensembl 2018.

Zerbino DR, Achuthan P, Akanni W, Amode MR, Barrell D, Bhai J, Billis K, Cummins C, Gall A, Girón CG, Gil L, Gordon L, Haggerty L, Haskell E, Hourlier T, Izuogu OG, Janacek SH, Juettemann T, To JK, Laird MR, Lavidas I, Liu Z, Loveland JE, Maurel T, McLaren W, Moore B, Mudge J, Murphy DN, Newman V, Nuhn M, Ogeh D, Ong CK, Parker A, Patricio M, Riat HS, Schuilenburg H, Sheppard D, Sparrow H, Taylor K, Thormann A, Vullo A, Walts B, Zadissa A, Frankish A, Hunt SE, Kostadima M, Langridge N, Martin FJ, Muffato M, Perry E, Ruffier M, Staines DM, Trevanion SJ, Aken BL, Cunningham F, Yates A, Flicek P.

Nucleic Acids Res. 2018 Jan 4;46(D1):D754-D761. doi: 10.1093/nar/gkx1098.

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