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Digital eye strain: prevalence, measurement and amelioration.

Sheppard AL, Wolffsohn JS.

BMJ Open Ophthalmol. 2018 Apr 16;3(1):e000146. doi: 10.1136/bmjophth-2018-000146. eCollection 2018. Review.


Adverse birth outcomes in relation to maternal marital and cohabitation status in Canada.

Shapiro GD, Bushnik T, Wilkins R, Kramer MS, Kaufman JS, Sheppard AJ, Yang S.

Ann Epidemiol. 2018 Aug;28(8):503-509.e11. doi: 10.1016/j.annepidem.2018.05.001. Epub 2018 May 22.


Dietary Micronutrients Promote Neuronal Differentiation by Modulating the Mitochondrial-Nuclear Dialogue.

Xie K, Sheppard A.

Bioessays. 2018 Jul;40(7):e1800051. doi: 10.1002/bies.201800051. Epub 2018 Jun 7. Review.


Streptococcus agalactiae that caused meningitis in healthy adults in 1998 are ST283, the same type that caused a food-borne outbreak of invasive sepsis in 2015: an observational molecular epidemiology study.

Barkham T, Sheppard A, Jones N, Chen SL.

Clin Microbiol Infect. 2018 Aug;24(8):923-925. doi: 10.1016/j.cmi.2018.04.006. Epub 2018 Apr 12. No abstract available.


New Weapons in the Toad Toolkit: A Review of Methods to Control and Mitigate the Biodiversity Impacts of Invasive Cane Toads (Rhinella Marina).

Tingley R, Ward-Fear G, Schwarzkopf L, Greenlees MJ, Phillips BL, Brown G, Clulow S, Webb J, Capon R, Sheppard A, Strive T, Tizard M, Shine R.

Q Rev Biol. 2017 Jun;92(2):123-49. Review.


Tailoring and field-testing the use of a knowledge translation peer support shared decision making strategy with First Nations, Inuit and Métis people making decisions about their cancer care: a study protocol.

Jull J, Mazereeuw M, Sheppard A, Kewayosh A, Steiner R, Graham ID.

Res Involv Engagem. 2018 Mar 1;4:6. doi: 10.1186/s40900-018-0085-3. eCollection 2018.


Is Noise in the MR Imager a Significant Risk Factor for Hearing Loss?

Salvi R, Sheppard A.

Radiology. 2018 Feb;286(2):609-610. doi: 10.1148/radiol.2017172221. No abstract available.


Linear iterative near-field phase retrieval (LIPR) for dual-energy x-ray imaging and material discrimination.

Li HT, Kingston AM, Myers GR, Beeching L, Sheppard AP.

J Opt Soc Am A Opt Image Sci Vis. 2018 Jan 1;35(1):A30-A39. doi: 10.1364/JOSAA.35.000A30.


Severe infections emerge from commensal bacteria by adaptive evolution.

Young BC, Wu CH, Gordon NC, Cole K, Price JR, Liu E, Sheppard AE, Perera S, Charlesworth J, Golubchik T, Iqbal Z, Bowden R, Massey RC, Paul J, Crook DW, Peto TE, Walker AS, Llewelyn MJ, Wyllie DH, Wilson DJ.

Elife. 2017 Dec 19;6. pii: e30637. doi: 10.7554/eLife.30637.


Birth outcomes among First Nations, Inuit and Métis populations.

Sheppard AJ, Shapiro GD, Bushnik T, Wilkins R, Perry S, Kaufman JS, Kramer MS, Yang S.

Health Rep. 2017 Nov 15;28(11):11-16.


Comparison of DNA quality in raw and reconstituted milk during sterilization.

Liao J, Yang L, Sheppard AM, Liu YF.

J Dairy Sci. 2018 Jan;101(1):147-153. doi: 10.3168/jds.2017-13461. Epub 2017 Nov 2.


High Rates of Human Fecal Carriage of mcr-1-Positive Multidrug-Resistant Enterobacteriaceae Emerge in China in Association With Successful Plasmid Families.

Zhong LL, Phan HTT, Shen C, Vihta KD, Sheppard AE, Huang X, Zeng KJ, Li HY, Zhang XF, Patil S, Crook DW, Walker AS, Xing Y, Lin JL, Feng LQ, Doi Y, Xia Y, Stoesser N, Tian GB.

Clin Infect Dis. 2018 Feb 10;66(5):676-685. doi: 10.1093/cid/cix885.


Resolving plasmid structures in Enterobacteriaceae using the MinION nanopore sequencer: assessment of MinION and MinION/Illumina hybrid data assembly approaches.

George S, Pankhurst L, Hubbard A, Votintseva A, Stoesser N, Sheppard AE, Mathers A, Norris R, Navickaite I, Eaton C, Iqbal Z, Crook DW, Phan HTT.

Microb Genom. 2017 Jun 9;3(8):e000118. doi: 10.1099/mgen.0.000118. eCollection 2017 Aug.


Complete genome sequence of the nematicidal Bacillus thuringiensis MYBT18247.

Hollensteiner J, Poehlein A, Spröer C, Bunk B, Sheppard AE, Rosenstiel P, Schulenburg H, Liesegang H.

J Biotechnol. 2017 Oct 20;260:48-52. doi: 10.1016/j.jbiotec.2017.09.003. Epub 2017 Sep 9.


Complete Genome sequence of the nematicidal Bacillus thuringiensis MYBT18246.

Hollensteiner J, Poehlein A, Spröer C, Bunk B, Sheppard AE, Rosentstiel P, Schulenburg H, Liesegang H.

Stand Genomic Sci. 2017 Aug 24;12:48. doi: 10.1186/s40793-017-0259-x. eCollection 2017.


Safe and effective biocontrol of common carp.

McColl KA, Sheppard AW, Barwick M.

Nat Ecol Evol. 2017 Apr 3;1(5):134. doi: 10.1038/s41559-017-0134. No abstract available.


DNA methylation of Th2 lineage determination genes at birth is associated with allergic outcomes in childhood.

Barton SJ, Ngo S, Costello P, Garratt E, El-Heis S, Antoun E, Clarke-Harris R, Murray R, Bhatt T, Burdge G, Cooper C, Inskip H, van der Beek EM, Sheppard A, Godfrey KM, Lillycrop KA; EpiGen Consortium.

Clin Exp Allergy. 2017 Dec;47(12):1599-1608. doi: 10.1111/cea.12988. Epub 2017 Aug 31.


Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli.

Stoesser N, Sheppard AE, Peirano G, Anson LW, Pankhurst L, Sebra R, Phan HTT, Kasarskis A, Mathers AJ, Peto TEA, Bradford P, Motyl MR, Walker AS, Crook DW, Pitout JD.

Sci Rep. 2017 Jul 19;7(1):5917. doi: 10.1038/s41598-017-06256-2.


Prolonged low-level noise-induced plasticity in the peripheral and central auditory system of rats.

Sheppard AM, Chen GD, Manohar S, Ding D, Hu BH, Sun W, Zhao J, Salvi R.

Neuroscience. 2017 Sep 17;359:159-171. doi: 10.1016/j.neuroscience.2017.07.005. Epub 2017 Jul 13.


Development of a rapid mitochondrial DNA extraction method for species identification in milk and milk products.

Liao J, Liu YF, Yang L, Li FP, Sheppard AM.

J Dairy Sci. 2017 Sep;100(9):7035-7040. doi: 10.3168/jds.2017-12653. Epub 2017 Jun 28.


Light manipulation of mosquito behaviour: acute and sustained photic suppression of biting activity in the Anopheles gambiae malaria mosquito.

Sheppard AD, Rund SSC, George GF, Clark E, Acri DJ, Duffield GE.

Parasit Vectors. 2017 Jun 16;10(1):255. doi: 10.1186/s13071-017-2196-3.


Refraction during incipient presbyopia: The Aston Longitudinal Assessment of Presbyopia (ALAP) study.

Laughton DS, Sheppard AL, Davies LN.

J Optom. 2018 Jan - Mar;11(1):49-56. doi: 10.1016/j.optom.2017.02.001. Epub 2017 Jun 7.


A curated dataset of complete Enterobacteriaceae plasmids compiled from the NCBI nucleotide database.

Orlek A, Phan H, Sheppard AE, Doumith M, Ellington M, Peto T, Crook D, Walker AS, Woodford N, Anjum MF, Stoesser N.

Data Brief. 2017 Apr 23;12:423-426. doi: 10.1016/j.dib.2017.04.024. eCollection 2017 Jun.


Enhanced Klebsiella pneumoniae Carbapenemase Expression from a Novel Tn4401 Deletion.

Cheruvanky A, Stoesser N, Sheppard AE, Crook DW, Hoffman PS, Weddle E, Carroll J, Sifri CD, Chai W, Barry K, Ramakrishnan G, Mathers AJ.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00025-17. doi: 10.1128/AAC.00025-17. Print 2017 Jun.


Molecular Evidence for Differential Long-term Outcomes of Early Life Severe Acute Malnutrition.

Sheppard A, Ngo S, Li X, Boyne M, Thompson D, Pleasants A, Gluckman P, Forrester T.

EBioMedicine. 2017 Apr;18:274-280. doi: 10.1016/j.ebiom.2017.03.001. Epub 2017 Mar 8.


Does transient increase in axial length during accommodation attenuate with age?

Laughton DS, Sheppard AL, Mallen EAH, Read SA, Davies LN.

Clin Exp Optom. 2017 Nov;100(6):676-682. doi: 10.1111/cxo.12533. Epub 2017 Mar 12.


Ordering the mob: Insights into replicon and MOB typing schemes from analysis of a curated dataset of publicly available plasmids.

Orlek A, Phan H, Sheppard AE, Doumith M, Ellington M, Peto T, Crook D, Walker AS, Woodford N, Anjum MF, Stoesser N.

Plasmid. 2017 May;91:42-52. doi: 10.1016/j.plasmid.2017.03.002. Epub 2017 Mar 9.


Plasmid Classification in an Era of Whole-Genome Sequencing: Application in Studies of Antibiotic Resistance Epidemiology.

Orlek A, Stoesser N, Anjum MF, Doumith M, Ellington MJ, Peto T, Crook D, Woodford N, Walker AS, Phan H, Sheppard AE.

Front Microbiol. 2017 Feb 9;8:182. doi: 10.3389/fmicb.2017.00182. eCollection 2017.


Both canonical and noncanonical Wnt signalling may be required for detoxification following ETP class mycotoxin exposure.

Zhang J, Pan Z, Sheppard A.

Toxicol Lett. 2017 Apr 5;271:12-19. doi: 10.1016/j.toxlet.2017.02.006. Epub 2017 Feb 11.


Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare.

Mathers AJ, Stoesser N, Chai W, Carroll J, Barry K, Cherunvanky A, Sebra R, Kasarskis A, Peto TE, Walker AS, Sifri CD, Crook DW, Sheppard AE.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01823-16. doi: 10.1128/AAC.01823-16. Print 2017 Mar.


Missing paternal data and adverse birth outcomes in Canada.

Shapiro GD, Bushnik T, Sheppard AJ, Kramer MS, Kaufman JS, Yang S.

Health Rep. 2016 Dec 21;27(12):3-9.


Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

Stoesser N, Sheppard AE, Peirano G, Sebra R, Lynch T, Anson L, Kasarskis A, Motyl MR, Crook DW, Pitout JD.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6948-6951. doi: 10.1128/AAC.01130-16. Print 2016 Nov.


Maternal colonization with Streptococcus agalactiae and associated stillbirth and neonatal disease in coastal Kenya.

Seale AC, Koech AC, Sheppard AE, Barsosio HC, Langat J, Anyango E, Mwakio S, Mwarumba S, Morpeth SC, Anampiu K, Vaughan A, Giess A, Mogeni P, Walusuna L, Mwangudzah H, Mwanzui D, Salim M, Kemp B, Jones C, Mturi N, Tsofa B, Mumbo E, Mulewa D, Bandika V, Soita M, Owiti M, Onzere N, Walker AS, Schrag SJ, Kennedy SH, Fegan G, Crook DW, Berkley JA.

Nat Microbiol. 2016 May 23;1(7):16067. doi: 10.1038/nmicrobiol.2016.67.


Genome-wide profiling of 24 hr diel rhythmicity in the water flea, Daphnia pulex: network analysis reveals rhythmic gene expression and enhances functional gene annotation.

Rund SS, Yoo B, Alam C, Green T, Stephens MT, Zeng E, George GF, Sheppard AD, Duffield GE, Milenković T, Pfrender ME.

BMC Genomics. 2016 Aug 18;17:653. doi: 10.1186/s12864-016-2998-2.


Paternal education and adverse birth outcomes in Canada.

Shapiro GD, Bushnik T, Sheppard AJ, Kramer MS, Kaufman JS, Yang S.

J Epidemiol Community Health. 2017 Jan;71(1):67-72. doi: 10.1136/jech-2015-206894. Epub 2016 Jun 24.


Global threat to agriculture from invasive species.

Paini DR, Sheppard AW, Cook DC, De Barro PJ, Worner SP, Thomas MB.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7575-9. doi: 10.1073/pnas.1602205113. Epub 2016 Jun 20.


Horizontal Transfer of Carbapenemase-Encoding Plasmids and Comparison with Hospital Epidemiology Data.

Hardiman CA, Weingarten RA, Conlan S, Khil P, Dekker JP, Mathers AJ, Sheppard AE, Segre JA, Frank KM.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4910-9. doi: 10.1128/AAC.00014-16. Print 2016 Aug.


First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

Stoesser N, Sheppard AE, Peirano G, Sebra RP, Lynch T, Anson LW, Kasarskis A, Motyl MR, Crook DW, Pitout JD.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5068-71. doi: 10.1128/AAC.00840-16. Print 2016 Aug.


Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC.

Sheppard AE, Stoesser N, Wilson DJ, Sebra R, Kasarskis A, Anson LW, Giess A, Pankhurst LJ, Vaughan A, Grim CJ, Cox HL, Yeh AJ; Modernising Medical Microbiology (MMM) Informatics Group, Sifri CD, Walker AS, Peto TE, Crook DW, Mathers AJ.

Antimicrob Agents Chemother. 2016 May 23;60(6):3767-78. doi: 10.1128/AAC.00464-16. Print 2016 Jun.


Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131.

Stoesser N, Sheppard AE, Pankhurst L, De Maio N, Moore CE, Sebra R, Turner P, Anson LW, Kasarskis A, Batty EM, Kos V, Wilson DJ, Phetsouvanh R, Wyllie D, Sokurenko E, Manges AR, Johnson TJ, Price LB, Peto TE, Johnson JR, Didelot X, Walker AS, Crook DW; Modernizing Medical Microbiology Informatics Group (MMMIG).

MBio. 2016 Mar 22;7(2):e02162. doi: 10.1128/mBio.02162-15.


N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

Ding D, Jiang H, Chen GD, Longo-Guess C, Muthaiah VP, Tian C, Sheppard A, Salvi R, Johnson KR.

Aging (Albany NY). 2016 Apr;8(4):730-50. doi: 10.18632/aging.100927.


Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.

Sheppard AE, Vaughan A, Jones N, Turner P, Turner C, Efstratiou A, Patel D; Modernising Medical Microbiology Informatics Group, Walker AS, Berkley JA, Crook DW, Seale AC.

J Clin Microbiol. 2016 May;54(5):1388-90. doi: 10.1128/JCM.03142-15. Epub 2016 Mar 9.


ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs.

Lee MH, Goralczyk AG, Kriszt R, Ang XM, Badowski C, Li Y, Summers SA, Toh SA, Yassin MS, Shabbir A, Sheppard A, Raghunath M.

Sci Rep. 2016 Feb 17;6:21173. doi: 10.1038/srep21173.


Gestational diabetic transcriptomic profiling of microdissected human trophoblast.

Bari MF, Ngo S, Bastie CC, Sheppard AM, Vatish M.

J Endocrinol. 2016 Apr;229(1):47-59. doi: 10.1530/JOE-15-0424. Epub 2016 Feb 11.


Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae Strain CAV1193.

Sheppard AE, Stoesser N, Sebra R, Kasarskis A, Deikus G, Anson L, Walker AS, Peto TE, Crook DW, Mathers AJ.

Genome Announc. 2016 Jan 28;4(1). pii: e01649-15. doi: 10.1128/genomeA.01649-15.


The 2006 Canadian Birth-Census Cohort.

Bushnik T, Yang S, Kramer MS, Kaufman JS, Sheppard AJ, Wilkins R.

Health Rep. 2016 Jan 20;27(1):11-9.


The Stealthy Superbug: the Role of Asymptomatic Enteric Carriage in Maintaining a Long-Term Hospital Outbreak of ST228 Methicillin-Resistant Staphylococcus aureus.

Senn L, Clerc O, Zanetti G, Basset P, Prod'hom G, Gordon NC, Sheppard AE, Crook DW, James R, Thorpe HA, Feil EJ, Blanc DS.

MBio. 2016 Jan 19;7(1):e02039-15. doi: 10.1128/mBio.02039-15.


Noise trauma induced plastic changes in brain regions outside the classical auditory pathway.

Chen GD, Sheppard A, Salvi R.

Neuroscience. 2016 Feb 19;315:228-45. doi: 10.1016/j.neuroscience.2015.12.005. Epub 2015 Dec 14.


High instability of a nematicidal Cry toxin plasmid in Bacillus thuringiensis.

Sheppard AE, Nakad R, Saebelfeld M, Masche AC, Dierking K, Schulenburg H.

J Invertebr Pathol. 2016 Jan;133:34-40. doi: 10.1016/j.jip.2015.11.009. Epub 2015 Nov 22.


MicroRNA Expression Relating to Dietary-Induced Liver Steatosis and NASH.

Zarfeshani A, Ngo S, Sheppard AM.

J Clin Med. 2015 Nov 16;4(11):1938-50. doi: 10.3390/jcm4111938. Review.

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