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Clinical and Diffusion Tensor MRI Findings in Congenital Homonymous Hemianopia.

Rispoli J, Seay M, Sum M, Rucker JC, Shepherd TM.

J Neuroophthalmol. 2019 Mar 7. doi: 10.1097/WNO.0000000000000770. [Epub ahead of print] No abstract available.


n → π* Interactions in N-Acyl Homoserine Lactone (AHL) Derivatives and Their Effects on Hydrolysis Rates.

Schmucker DJ, Dunbar SR, Shepherd TD, Bertucci MA.

J Phys Chem A. 2019 Mar 11. doi: 10.1021/acs.jpca.8b12266. [Epub ahead of print]


Role of temperature on the development of hypoxia in blackwater from grass.

Vithana CL, Sullivan LA, Shepherd T.

Sci Total Environ. 2019 Feb 26;667:152-159. doi: 10.1016/j.scitotenv.2019.02.386. [Epub ahead of print]


Spatial distribution of multiple sclerosis lesions in the cervical spinal cord.

Eden D, Gros C, Badji A, Dupont SM, De Leener B, Maranzano J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Stawiarz L, Hillert J, Talbott J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith SA, Andrada Treaba C, Mainero C, Lefeuvre J, Reich DS, Nair G, Shepherd TM, Charlson E, Tachibana Y, Hori M, Kamiya K, Chougar L, Narayanan S, Cohen-Adad J.

Brain. 2019 Mar 1;142(3):633-646. doi: 10.1093/brain/awy352.


3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 1: Brain Stem.

Hoch MJ, Bruno MT, Faustin A, Cruz N, Crandall L, Wisniewski T, Devinsky O, Shepherd TM.

AJNR Am J Neuroradiol. 2019 Mar;40(3):401-407. doi: 10.3174/ajnr.A5956. Epub 2019 Jan 31.


Toward greater involvement of youth with complex communication needs in the selection of augmentative and alternative communication devices.

Swett C, Surins H, Welton C, Shepherd TA, Renzoni AM, Ryan SE.

Disabil Rehabil Assist Technol. 2019 Jan 17:1-9. doi: 10.1080/17483107.2018.1534997. [Epub ahead of print]


Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target.

Fernandez ML, Dawson A, Hoenisch J, Kim H, Bamford S, Salamanca C, DiMattia G, Shepherd T, Cremona M, Hennessy B, Anderson S, Volik S, Collins CC, Huntsman DG, Carey MS.

Cancer Cell Int. 2019 Jan 8;19:10. doi: 10.1186/s12935-019-0725-1. eCollection 2019.


Autonomously designed free-form 2D DNA origami.

Jun H, Zhang F, Shepherd T, Ratanalert S, Qi X, Yan H, Bathe M.

Sci Adv. 2019 Jan 4;5(1):eaav0655. doi: 10.1126/sciadv.aav0655. eCollection 2019 Jan.


Automated Sequence Design of 3D Polyhedral Wireframe DNA Origami with Honeycomb Edges.

Jun H, Shepherd TR, Zhang K, Bricker WP, Li S, Chiu W, Bathe M.

ACS Nano. 2019 Feb 26;13(2):2083-2093. doi: 10.1021/acsnano.8b08671. Epub 2019 Jan 24.


Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

Kessler DS, MacNeill SJ, Tallon D, Lewis G, Peters TJ, Hollingworth W, Round J, Burns A, Chew-Graham CA, Anderson IM, Shepherd T, Campbell J, Dickens CM, Carter M, Jenkinson C, Macleod U, Gibson H, Davies S, Wiles NJ.

BMJ. 2018 Oct 31;363:k4218. doi: 10.1136/bmj.k4218.


Could Mesophases Play a Role in the Nucleation and Polymorph Selection of Zeolites?

Kumar A, Nguyen AH, Okumu R, Shepherd TD, Molinero V.

J Am Chem Soc. 2018 Nov 28;140(47):16071-16086. doi: 10.1021/jacs.8b06664. Epub 2018 Nov 13.


Responsiveness of a parent-reported outcome measure to evaluate AAC interventions for children and youth with complex communication needs.

Ryan SE, Shepherd TA, Renzoni AM, Servais M, Kingsnorth S, Laskey C, Ward K, Bradley K.

Augment Altern Commun. 2018 Dec;34(4):348-358. doi: 10.1080/07434618.2018.1520296. Epub 2018 Oct 29.


Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG.

Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4.


Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks.

Gros C, De Leener B, Badji A, Maranzano J, Eden D, Dupont SM, Talbott J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Tachibana Y, Hori M, Kamiya K, Chougar L, Stawiarz L, Hillert J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith S, Treaba CA, Mainero C, Lefeuvre J, Reich DS, Nair G, Auclair V, McLaren DG, Martin AR, Fehlings MG, Vahdat S, Khatibi A, Doyon J, Shepherd T, Charlson E, Narayanan S, Cohen-Adad J.

Neuroimage. 2019 Jan 1;184:901-915. doi: 10.1016/j.neuroimage.2018.09.081. Epub 2018 Oct 6.


Visual detection of regional brain hypometabolism in cognitively impaired patients is independent of positron emission tomography-magnetic resonance attenuation correction method.

Franceschi AM, Abballe V, Raad RA, Nelson A, Jackson K, Babb J, Vahle T, Fenchel M, Zhan Y, Valadez GH, Shepherd TM, Friedman KP.

World J Nucl Med. 2018 Jul-Sep;17(3):188-194. doi: 10.4103/wjnm.WJNM_61_17.


Accelerated Internal Auditory Canal Screening Magnetic Resonance Imaging Protocol With Compressed Sensing 3-Dimensional T2-Weighted Sequence.

Yuhasz M, Hoch MJ, Hagiwara M, Bruno MT, Babb JS, Raithel E, Forman C, Anwar A, Thomas Roland J Jr, Shepherd TM.

Invest Radiol. 2018 Dec;53(12):742-747. doi: 10.1097/RLI.0000000000000499.


A Rare Case of Composite Dural Extranodal Marginal Zone Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Bustoros M, Liechty B, Zagzag D, Liu C, Shepherd T, Gruber D, Raphael B, Placantonakis DG.

Front Neurol. 2018 Apr 24;9:267. doi: 10.3389/fneur.2018.00267. eCollection 2018. Review.


In vitro synthesis of gene-length single-stranded DNA.

Veneziano R, Shepherd TR, Ratanalert S, Bellou L, Tao C, Bathe M.

Sci Rep. 2018 Apr 25;8(1):6548. doi: 10.1038/s41598-018-24677-5.


Multimodel Evidence for an Atmospheric Circulation Response to Arctic Sea Ice Loss in the CMIP5 Future Projections.

Zappa G, Pithan F, Shepherd TG.

Geophys Res Lett. 2018 Jan 28;45(2):1011-1019. doi: 10.1002/2017GL076096. Epub 2018 Jan 24.


Post-depositional behaviour of mercury and arsenic in submarine mine tailings deposited in Buyat Bay, North Sulawesi, Indonesia.

Shepherd T, Rumengan I, Sahami A.

Mar Environ Res. 2018 Jun;137:88-97. doi: 10.1016/j.marenvres.2018.02.028. Epub 2018 Feb 26.


A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: The NOTEPAD study Protocol.

Burroughs H, Bartlam B, Ray M, Kingstone T, Shepherd T, Ogollah R, Proctor J, Waheed W, Bower P, Bullock P, Lovell K, Gilbody S, Bailey D, Butler-Whalley S, Chew-Graham C.

Trials. 2018 Mar 7;19(1):172. doi: 10.1186/s13063-018-2550-6.


Twins as Participants in Randomized Controlled Trials: A Review of Published Literature.

Sumathipala A, Yelland L, Green D, Shepherd T, Jayaweera K, Ferreira P, Craig JM.

Twin Res Hum Genet. 2018 Feb;21(1):51-56. doi: 10.1017/thg.2017.67. Epub 2017 Dec 28. Review.


Osimertinib Dose Escalation Induces Regression of Progressive EGFR T790M-Mutant Leptomeningeal Lung Adenocarcinoma.

Cordova C, Chi AS, Chachoua A, Kondziolka D, Silverman JS, Shepherd TM, Jain R, Snuderl M.

J Thorac Oncol. 2017 Nov;12(11):e188-e190. doi: 10.1016/j.jtho.2017.07.029. No abstract available.


Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.

Fales KR, Njoroge FG, Brooks HB, Thibodeaux S, Torrado A, Si C, Toth JL, Mc Cowan JR, Roth KD, Thrasher KJ, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Margolis BJ, Wu Z, Wang Y, Atwell S, Wang J, Hui YH, Meier TI, Konicek SA, Geeganage S.

J Med Chem. 2017 Dec 14;60(23):9599-9616. doi: 10.1021/acs.jmedchem.7b01046. Epub 2017 Nov 9.


Husk to caryopsis adhesion in barley is influenced by pre- and post-anthesis temperatures through changes in a cuticular cementing layer on the caryopsis.

Brennan M, Shepherd T, Mitchell S, Topp CFE, Hoad SP.

BMC Plant Biol. 2017 Oct 23;17(1):169. doi: 10.1186/s12870-017-1113-4.


De novo design and synthesis of a 30-cistron translation-factor module.

Shepherd TR, Du L, Liljeruhm J, Samudyata, Wang J, Sjödin MOD, Wetterhall M, Yomo T, Forster AC.

Nucleic Acids Res. 2017 Oct 13;45(18):10895-10905. doi: 10.1093/nar/gkx753.


Digoxin Is Associated With Increased Shock Events and Electrical Storms in Patients With Implantable Cardioverter Defibrillators.

Mina GS, Acharya M, Shepherd T, Gobrial G, Tekeste M, Watti H, Bhandari R, Saini A, Reddy P, Dominic P.

J Cardiovasc Pharmacol Ther. 2018 Mar;23(2):142-148. doi: 10.1177/1074248417732416. Epub 2017 Sep 22.


Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential.

Tong JG, Valdes YR, Sivapragasam M, Barrett JW, Bell JC, Stojdl D, DiMattia GE, Shepherd TG.

BMC Cancer. 2017 Aug 30;17(1):594. doi: 10.1186/s12885-017-3600-2.


Orthodontic braces come back to bite: a novel presentation of a small bowel volvulus.

Shepherd T, Teo A, Naunton-Morgan R.

BMJ Case Rep. 2017 Aug 7;2017. pii: bcr-2017-221152. doi: 10.1136/bcr-2017-221152. No abstract available.


Effect of schwertmannite and jarosite on the formation of hypoxic blackwater during inundation of grass material.

Vithana CL, Sullivan LA, Shepherd T.

Water Res. 2017 Nov 1;124:1-10. doi: 10.1016/j.watres.2017.07.039. Epub 2017 Jul 17.


Developing a community-based psycho-social intervention with older people and third sector workers for anxiety and depression: a qualitative study.

Kingstone T, Burroughs H, Bartlam B, Ray M, Proctor J, Shepherd T, Bullock P, Chew-Graham CA.

BMC Fam Pract. 2017 Jul 12;18(1):77. doi: 10.1186/s12875-017-0648-7.


Clinical utility for diffusion MRI sequence in emergency and inpatient spine protocols.

Hoch MJ, Rispoli J, Bruno M, Wauchope M, Lui YW, Shepherd TM.

Clin Imaging. 2017 Sep - Oct;45:37-50. doi: 10.1016/j.clinimag.2017.05.021. Epub 2017 Jun 6.


Toward a standard for the evaluation of PET-Auto-Segmentation methods following the recommendations of AAPM task group No. 211: Requirements and implementation.

Berthon B, Spezi E, Galavis P, Shepherd T, Apte A, Hatt M, Fayad H, De Bernardi E, Soffientini CD, Ross Schmidtlein C, El Naqa I, Jeraj R, Lu W, Das S, Zaidi H, Mawlawi OR, Visvikis D, Lee JA, Kirov AS.

Med Phys. 2017 Aug;44(8):4098-4111. doi: 10.1002/mp.12312. Epub 2017 Jul 2.


Advanced MRI of the Optic Nerve.

Hoch MJ, Bruno MT, Shepherd TM.

J Neuroophthalmol. 2017 Jun;37(2):187-196. doi: 10.1097/WNO.0000000000000511. Review.


Patient Outcomes at Urban and Suburban Level I Versus Level II Trauma Centers.

Kaji AH, Bosson N, Gausche-Hill M, Dawes AJ, Putnam B, Shepherd T, Lewis RJ.

Ann Emerg Med. 2017 Aug;70(2):161-168. doi: 10.1016/j.annemergmed.2017.01.040. Epub 2017 Feb 28.


New rapid, accurate T2 quantification detects pathology in normal-appearing brain regions of relapsing-remitting MS patients.

Shepherd TM, Kirov II, Charlson E, Bruno M, Babb J, Sodickson DK, Ben-Eliezer N.

Neuroimage Clin. 2017 Feb 3;14:363-370. doi: 10.1016/j.nicl.2017.01.029. eCollection 2017.


Medically unexplained symptoms: continuing challenges for primary care.

Chew-Graham CA, Heyland S, Kingstone T, Shepherd T, Buszewicz M, Burroughs H, Sumathipala A.

Br J Gen Pract. 2017 Mar;67(656):106-107. doi: 10.3399/bjgp17X689473. No abstract available.


Electrical stimulation and monitoring devices of the CNS: An imaging review.

Patel SH, Halpern CH, Shepherd TM, Timpone VM.

J Neuroradiol. 2017 Jun;44(3):175-184. doi: 10.1016/j.neurad.2016.12.005. Epub 2017 Feb 7. Review.


Classification and evaluation strategies of auto-segmentation approaches for PET: Report of AAPM task group No. 211.

Hatt M, Lee JA, Schmidtlein CR, Naqa IE, Caldwell C, De Bernardi E, Lu W, Das S, Geets X, Gregoire V, Jeraj R, MacManus MP, Mawlawi OR, Nestle U, Pugachev AB, Schöder H, Shepherd T, Spezi E, Visvikis D, Zaidi H, Kirov AS.

Med Phys. 2017 Jun;44(6):e1-e42. doi: 10.1002/mp.12124. Epub 2017 May 18.


Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.

Liu X, Speckhard DC, Shepherd TR, Sun YJ, Hengel SR, Yu L, Fowler CA, Gakhar L, Fuentes EJ.

Structure. 2016 Dec 6;24(12):2053-2066. doi: 10.1016/j.str.2016.08.019. Epub 2016 Oct 27.


Differences in MEK inhibitor efficacy in molecularly characterized low-grade serous ovarian cancer cell lines.

Fernández ML, DiMattia GE, Dawson A, Bamford S, Anderson S, Hennessy BT, Anglesio MS, Shepherd TG, Salamanca C, Hoenisch J, Tinker A, Huntsman DG, Carey MS.

Am J Cancer Res. 2016 Oct 1;6(10):2235-2251. eCollection 2016.


Palliative CT-Guided Cordotomy for Medically Intractable Pain in Patients with Cancer.

Shepherd TM, Hoch MJ, Cohen BA, Bruno MT, Fieremans E, Rosen G, Pacione D, Mogilner AY.

AJNR Am J Neuroradiol. 2017 Feb;38(2):387-390. doi: 10.3174/ajnr.A4981. Epub 2016 Nov 3.


Track density imaging of hypertrophic olivary degeneration from multiple sclerosis plaque.

Hoch MJ, Chung S, Fatterpekar GM, Kister I, Shepherd TM.

BJR Case Rep. 2016 Nov 2;2(4):20150299. doi: 10.1259/bjrcr.20150299. eCollection 2016.


Brain structural profile of multiple system atrophy patients with cognitive impairment.

Fiorenzato E, Weis L, Seppi K, Onofrj M, Cortelli P, Zanigni S, Tonon C, Kaufmann H, Shepherd TM, Poewe W, Krismer F, Wenning G, Antonini A, Biundo R; Movement Disorders Society MSA (MODIMSA) Neuropsychology and Imaging Study Groups.

J Neural Transm (Vienna). 2017 Mar;124(3):293-302. doi: 10.1007/s00702-016-1636-0. Epub 2016 Oct 24.


Field-based Evaluation of a Novel SPME-GC-MS Method for Investigation of Below-ground Interaction between Brassica Roots and Larvae of Cabbage Root Fly, Delia radicum L.

Deasy W, Shepherd T, Alexander CJ, Birch AN, Evans KA.

Phytochem Anal. 2016 Nov;27(6):343-353. doi: 10.1002/pca.2634. Epub 2016 Sep 30.


Effects of a warming Arctic.

Shepherd TG.

Science. 2016 Sep 2;353(6303):989-990. No abstract available.


Impacts of parameterized orographic drag on the Northern Hemisphere winter circulation.

Sandu I, Bechtold P, Beljaars A, Bozzo A, Pithan F, Shepherd TG, Zadra A.

J Adv Model Earth Syst. 2016 Mar;8(1):196-211. Epub 2016 Feb 5.

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