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Items: 36


Closing five Emergency Departments in England between 2009 and 2011: the closED controlled interrupted time-series analysis.

Knowles E, Shephard N, Stone T, Bishop-Edwards L, Hirst E, Abouzeid L, Mason S, Nicholl J.

Southampton (UK): NIHR Journals Library; 2018 Jul.


The DiPEP study: an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum.

Goodacre S, Horspool K, Nelson-Piercy C, Knight M, Shephard N, Lecky F, Thomas S, Hunt BJ, Fuller G; DiPEP research group.

BJOG. 2018 May 21. doi: 10.1111/1471-0528.15286. [Epub ahead of print]


The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium.

Hunt BJ, Parmar K, Horspool K, Shephard N, Nelson-Piercy C, Goodacre S; DiPEP research group.

Br J Haematol. 2018 Mar;180(5):694-704. doi: 10.1111/bjh.15102. Epub 2018 Jan 23.


PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.

Julious SA, Horspool MJ, Davis S, Bradburn M, Norman P, Shephard N, Cooper CL, Smithson WH, Boote J, Elphick H, Loban A, Franklin M, Kua WS, May R, Campbell J, Williams R, Rex S, Bortolami O.

Health Technol Assess. 2016 Dec;20(93):1-154. doi: 10.3310/hta20930.


The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation.

Brown S, Tiernan J, Biggs K, Hind D, Shephard N, Bradburn M, Wailoo A, Alshreef A, Swaby L, Watson A, Radley S, Jones O, Skaife P, Agarwal A, Giordano P, Lamah M, Cartmell M, Davies J, Faiz O, Nugent K, Clarke A, MacDonald A, Conaghan P, Ziprin P, Makhija R.

Health Technol Assess. 2016 Nov;20(88):1-150.


Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial.

Brown SR, Tiernan JP, Watson AJM, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Alshreef A, Hind D; HubBLe Study team.

Lancet. 2016 Jul 23;388(10042):356-364. doi: 10.1016/S0140-6736(16)30584-0. Epub 2016 May 25. Erratum in: Lancet. 2016 Jul 23;388(10042):342.


Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study.

Teare MD, Dimairo M, Shephard N, Hayman A, Whitehead A, Walters SJ.

Trials. 2014 Jul 3;15:264. doi: 10.1186/1745-6215-15-264.


The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids.

Tiernan J, Hind D, Watson A, Wailoo AJ, Bradburn M, Shephard N, Biggs K, Brown S.

BMC Gastroenterol. 2012 Oct 25;12:153. doi: 10.1186/1471-230X-12-153.


Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis.

Glossop AJ, Shephard N, Bryden DC, Mills GH.

Br J Anaesth. 2012 Sep;109(3):305-14. doi: 10.1093/bja/aes270. Review. Erratum in: Br J Anaesth. 2013 Jan;110(1):164. Shepherd, N [corrected to Shephard, N].


Headgroup effect on silane structures at buried polymer/silane and polymer/polymer interfaces and their relations to adhesion.

Zhang C, Shephard NE, Rhodes SM, Chen Z.

Langmuir. 2012 Apr 10;28(14):6052-9. doi: 10.1021/la300004x. Epub 2012 Mar 28.


Pure-tone auditory thresholds are not chronically elevated in multiple sclerosis.

Doty RL, Tourbier I, Davis S, Rotz J, Cuzzocreo JL, Treem J, Shephard N, Pham DL.

Behav Neurosci. 2012 Apr;126(2):314-24. doi: 10.1037/a0027046. Epub 2012 Feb 6.


Phenolic resin surface restructuring upon exposure to humid air: a sum frequency generation vibrational spectroscopic study.

Lu X, Han J, Shephard N, Rhodes S, Martin AD, Li D, Xue G, Chen Z.

J Phys Chem B. 2009 Oct 1;113(39):12944-51. doi: 10.1021/jp9058092.


A breast cancer risk haplotype in the caspase-8 gene.

Shephard ND, Abo R, Rigas SH, Frank B, Lin WY, Brock IW, Shippen A, Balasubramanian SP, Reed MW, Bartram CR, Meindl A, Schmutzler RK, Engel C, Burwinkel B, Cannon-Albright LA, Allen-Brady K, Camp NJ, Cox A.

Cancer Res. 2009 Apr 1;69(7):2724-8. doi: 10.1158/0008-5472.CAN-08-4266. Epub 2009 Mar 24.


Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

Hinks A, Barton A, Shephard N, Eyre S, Bowes J, Cargill M, Wang E, Ke X, Kennedy GC, John S, Worthington J, Thomson W; British Society of Paediatric and Adolescent Rheumatology Study Group.

Arthritis Rheum. 2009 Jan;60(1):258-63. doi: 10.1002/art.24179.


Understanding molecular structures of silanes at buried polymer interfaces using sum frequency generation vibrational spectroscopy and relating interfacial structures to polymer adhesion.

Vázquez AV, Shephard NE, Steinecker CL, Ahn D, Spanninga S, Chen Z.

J Colloid Interface Sci. 2009 Mar 15;331(2):408-16. doi: 10.1016/j.jcis.2008.11.065. Epub 2008 Dec 6.


Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits.

Amos CI, Chen WV, Remmers E, Siminovitch KA, Seldin MF, Criswell LA, Lee AT, John S, Shephard ND, Worthington J, Cornelis F, Plenge RM, Begovich AB, Dyer TD, Kastner DL, Gregersen PK.

BMC Proc. 2007;1 Suppl 1:S3. Epub 2007 Dec 18.


Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus.

Gallego PH, Shephard N, Bulsara MK, van Bockxmeer FM, Powell BL, Beilby JP, Arscott G, Le Page M, Palmer LJ, Davis EA, Jones TW, Choong CS.

J Diabetes Complications. 2008 May-Jun;22(3):191-8. doi: 10.1016/j.jdiacomp.2007.03.003. Epub 2008 Apr 16.


Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes.

Sims AM, Shephard N, Carter K, Doan T, Dowling A, Duncan EL, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Thomas G, Wass JA, Brown MA.

J Bone Miner Res. 2008 Apr;23(4):499-506.


Association between osteopontin and human abdominal aortic aneurysm.

Golledge J, Muller J, Shephard N, Clancy P, Smallwood L, Moran C, Dear AE, Palmer LJ, Norman PE.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):655-60. Epub 2006 Dec 14.


Fine mapping of genes within the IDDM8 region in rheumatoid arthritis.

Hinks A, Barton A, John S, Shephard N, Worthington J.

Arthritis Res Ther. 2006;8(5):R145.


Linkage analysis of rheumatoid arthritis in US and UK families reveals interactions between HLA-DRB1 and loci on chromosomes 6q and 16p.

John S, Amos C, Shephard N, Chen W, Butterworth A, Etzel C, Jawaheer D, Seldin M, Silman A, Gregersen P, Worthington J.

Arthritis Rheum. 2006 May;54(5):1482-90.


In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype.

Chinoy H, Salway F, Fertig N, Shephard N, Tait BD, Thomson W, Isenberg DA, Oddis CV, Silman AJ, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC).

Arthritis Res Ther. 2006;8(1):R13.


Will the real disease gene please stand up?

Shephard N, John S, Cardon L, McCarthy MI, Zeggini E.

BMC Genet. 2005 Dec 30;6 Suppl 1:S66.


Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites.

John S, Shephard N, Liu G, Zeggini E, Cao M, Chen W, Vasavda N, Mills T, Barton A, Hinks A, Eyre S, Jones KW, Ollier W, Silman A, Gibson N, Worthington J, Kennedy GC.

Am J Hum Genet. 2004 Jul;75(1):54-64. Epub 2004 May 20.


Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.

Eyre S, Barton A, Shephard N, Hinks A, Brintnell W, MacKay K, Silman A, Ollier W, Wordsworth P, John S, Worthington J.

Arthritis Rheum. 2004 Mar;50(3):729-35.


Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure.

Shephard N, Falcaro M, Zeggini E, Chapman P, Hinks A, Barton A, Worthington J, Pickles A, John S.

BMC Genet. 2003 Dec 31;4 Suppl 1:S26.


Computationally intensive econometrics using a distributed matrix-programming language.

Doornik JA, Hendry DF, Shephard N.

Philos Trans A Math Phys Eng Sci. 2002 Jun 15;360(1795):1245-66.


Repeated dose study of sucralose tolerance in human subjects.

Baird IM, Shephard NW, Merritt RJ, Hildick-Smith G.

Food Chem Toxicol. 2000;38 Suppl 2:S123-9.


Interlaboratory variability of rotational chair test results II: analysis of simulated data.

Furman JM, Goebel JA, Hamid MA, Hanson J, Honrubia V, Peterka R, Schumann T, Shephard NT, Stockwell CW, Wall C.

Otolaryngol Head Neck Surg. 2000 Jan;122(1):23-30. Erratum in: Otolaryngol Head Neck Surg 2001 Nov;125(5):580.


Clinicopathological evidence that neovascularisation is a cause of recurrent varicose veins.

Nyamekye I, Shephard NA, Davies B, Heather BP, Earnshaw JJ.

Eur J Vasc Endovasc Surg. 1998 May;15(5):412-5.


Interlaboratory variability of rotational chair test results. Interlaboratory Rotational Chair Study Group.

Furman JM, Goebel JA, Hamid MA, Hanson J, Honrubia V, Peterka R, Schumann T, Shephard NT, Stockwell CW, Wall C.

Otolaryngol Head Neck Surg. 1994 Apr;110(4):400-5. Erratum in: Otolaryngol Head Neck Surg 2001 Nov;125(5):580.


Triglyceride lowering effect of MaxEPA fish lipid concentrate: a multicentre placebo controlled double blind study.

Miller JP, Heath ID, Choraria SK, Shephard NW, Gajendragadkar RV, Harcus AW, Batson GA, Smith DW, Saynor R.

Clin Chim Acta. 1988 Dec 30;178(3):251-9.


Consumption of quinine hydrochloride in tonic water.

Worden AN, Frape DL, Shephard NW.

Lancet. 1987 Jan 31;1(8527):271-2. No abstract available.


Comparison of tolmetin sodium with indomethacin in osteoarthritis.

Shephard NW, Steele CE.

Practitioner. 1981 Nov;225(1361):1696-7. No abstract available.


Bioavailability of potassium from controlled-release tablets with and without water loading.

Bechgaard H, Shephard NW.

Eur J Clin Pharmacol. 1981;21(2):143-7.


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