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Items: 15


Contribution of Host Immune Responses Against Influenza D Virus Infection Toward Secondary Bacterial Infection in a Mouse Model.

Skelton RM, Shepardson KM, Hatton A, Wilson PT, Sreenivasan C, Yu J, Wang D, Huber VC, Rynda-Apple A.

Viruses. 2019 Oct 29;11(11). pii: E994. doi: 10.3390/v11110994.


IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections.

Shepardson KM, Larson K, Johns LL, Stanek K, Cho H, Wellham J, Henderson H, Rynda-Apple A.

Front Immunol. 2018 Nov 9;9:2589. doi: 10.3389/fimmu.2018.02589. eCollection 2018.


Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis.

Caffrey-Carr AK, Hilmer KM, Kowalski CH, Shepardson KM, Temple RM, Cramer RA, Obar JJ.

Front Immunol. 2018 Jan 11;8:1984. doi: 10.3389/fimmu.2017.01984. eCollection 2017.


Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent.

Shepardson KM, Schwarz B, Larson K, Morton RV, Avera J, McCoy K, Caffrey A, Harmsen A, Douglas T, Rynda-Apple A.

mBio. 2017 Nov 14;8(6). pii: e01356-17. doi: 10.1128/mBio.01356-17.


Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.

Shepardson KM, Larson K, Morton RV, Prigge JR, Schmidt EE, Huber VC, Rynda-Apple A.

mBio. 2016 May 3;7(3). pii: e00506-16. doi: 10.1128/mBio.00506-16.


IL-1α signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge.

Caffrey AK, Lehmann MM, Zickovich JM, Espinosa V, Shepardson KM, Watschke CP, Hilmer KM, Thammahong A, Barker BM, Rivera A, Cramer RA, Obar JJ.

PLoS Pathog. 2015 Jan 28;11(1):e1004625. doi: 10.1371/journal.ppat.1004625. eCollection 2015 Jan.


Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection.

Jhingran A, Kasahara S, Shepardson KM, Junecko BA, Heung LJ, Kumasaka DK, Knoblaugh SE, Lin X, Kazmierczak BI, Reinhart TA, Cramer RA, Hohl TM.

PLoS Pathog. 2015 Jan 26;11(1):e1004589. doi: 10.1371/journal.ppat.1004589. eCollection 2015 Jan.


mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG.

Science. 2014 Sep 26;345(6204):1250684. doi: 10.1126/science.1250684. Erratum in: Science. 2014 Nov 7;346(6210):aaa1503. van der Meer, Brian M J W [corrected to van der Veer, Brian M J W].


Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection.

Shepardson KM, Jhingran A, Caffrey A, Obar JJ, Suratt BT, Berwin BL, Hohl TM, Cramer RA.

PLoS Pathog. 2014 Sep 25;10(9):e1004378. doi: 10.1371/journal.ppat.1004378. eCollection 2014 Sep.


Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus.

Chung D, Thammahong A, Shepardson KM, Blosser SJ, Cramer RA.

Mol Microbiol. 2014 Jun;92(6):1279-98. doi: 10.1111/mmi.12626. Epub 2014 May 9.


Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.

Marakalala MJ, Vautier S, Potrykus J, Walker LA, Shepardson KM, Hopke A, Mora-Montes HM, Kerrigan A, Netea MG, Murray GI, Maccallum DM, Wheeler R, Munro CA, Gow NA, Cramer RA, Brown AJ, Brown GD.

PLoS Pathog. 2013;9(4):e1003315. doi: 10.1371/journal.ppat.1003315. Epub 2013 Apr 18.


Fungal cell wall dynamics and infection site microenvironments: signal integration and infection outcome.

Shepardson KM, Cramer RA.

Curr Opin Microbiol. 2013 Aug;16(4):385-90. doi: 10.1016/j.mib.2013.03.003. Epub 2013 Apr 15.


Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation.

Shepardson KM, Ngo LY, Aimanianda V, Latgé JP, Barker BM, Blosser SJ, Iwakura Y, Hohl TM, Cramer RA.

Microbes Infect. 2013 Apr;15(4):259-69. doi: 10.1016/j.micinf.2012.11.010. Epub 2012 Dec 4.


Candida albicans induces arginine biosynthetic genes in response to host-derived reactive oxygen species.

Jiménez-López C, Collette JR, Brothers KM, Shepardson KM, Cramer RA, Wheeler RT, Lorenz MC.

Eukaryot Cell. 2013 Jan;12(1):91-100. doi: 10.1128/EC.00290-12. Epub 2012 Nov 9.


Hypoxia and fungal pathogenesis: to air or not to air?

Grahl N, Shepardson KM, Chung D, Cramer RA.

Eukaryot Cell. 2012 May;11(5):560-70. doi: 10.1128/EC.00031-12. Epub 2012 Mar 23. Review.

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