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Items: 12


Severity and properties of cardiac damage caused by Streptococcus pneumoniae are strain dependent.

Shenoy AT, Beno SM, Brissac T, Bell JW, Novak L, Orihuela CJ.

PLoS One. 2018 Sep 14;13(9):e0204032. doi: 10.1371/journal.pone.0204032. eCollection 2018.


Cell Invasion and Pyruvate Oxidase-Derived H2O2 Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing.

Brissac T, Shenoy AT, Patterson LA, Orihuela CJ.

Infect Immun. 2017 Dec 19;86(1). pii: e00569-17. doi: 10.1128/IAI.00569-17. Print 2018 Jan.


Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing.

Shenoy AT, Brissac T, Gilley RP, Kumar N, Wang Y, Gonzalez-Juarbe N, Hinkle WS, Daugherty SC, Shetty AC, Ott S, Tallon LJ, Deshane J, Tettelin H, Orihuela CJ.

PLoS Pathog. 2017 Aug 25;13(8):e1006582. doi: 10.1371/journal.ppat.1006582. eCollection 2017 Aug.


The Pneumococcal Serotype 15C Capsule Is Partially O-Acetylated and Allows for Limited Evasion of 23-Valent Pneumococcal Polysaccharide Vaccine-Elicited Anti-Serotype 15B Antibodies.

Spencer BL, Shenoy AT, Orihuela CJ, Nahm MH.

Clin Vaccine Immunol. 2017 Aug 4;24(8). pii: e00099-17. doi: 10.1128/CVI.00099-17. Print 2017 Aug.


Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F.

Spencer BL, Saad JS, Shenoy AT, Orihuela CJ, Nahm MH.

Infect Immun. 2017 Jun 20;85(7). pii: e00132-17. doi: 10.1128/IAI.00132-17. Print 2017 Jul.


Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties.

Lizcano A, Akula Suresh Babu R, Shenoy AT, Saville AM, Kumar N, D'Mello A, Hinojosa CA, Gilley RP, Segovia J, Mitchell TJ, Tettelin H, Orihuela CJ.

Microbes Infect. 2017 Jun;19(6):323-333. doi: 10.1016/j.micinf.2017.04.001. Epub 2017 Apr 10.


Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia.

González-Juarbe N, Bradley KM, Shenoy AT, Gilley RP, Reyes LF, Hinojosa CA, Restrepo MI, Dube PH, Bergman MA, Orihuela CJ.

Cell Death Differ. 2017 May;24(5):917-928. doi: 10.1038/cdd.2017.49. Epub 2017 Apr 7.


Killing of Serratia marcescens biofilms with chloramphenicol.

Ray C, Shenoy AT, Orihuela CJ, González-Juarbe N.

Ann Clin Microbiol Antimicrob. 2017 Mar 29;16(1):19. doi: 10.1186/s12941-017-0192-2.


A Non-Human Primate Model of Severe Pneumococcal Pneumonia.

Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto A, Orihuela CJ.

PLoS One. 2016 Nov 17;11(11):e0166092. doi: 10.1371/journal.pone.0166092. eCollection 2016.


Anatomical site-specific contributions of pneumococcal virulence determinants.

Shenoy AT, Orihuela CJ.

Pneumonia (Nathan). 2016;8. pii: 7. Epub 2016 Jun 3.


Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization.

Blanchette KA, Shenoy AT, Milner J 2nd, Gilley RP, McClure E, Hinojosa CA, Kumar N, Daugherty SC, Tallon LJ, Ott S, King SJ, Ferreira DM, Gordon SB, Tettelin H, Orihuela CJ.

Infect Immun. 2016 Sep 19;84(10):2922-32. doi: 10.1128/IAI.00277-16. Print 2016 Oct.


Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion.

Gilley RP, González-Juarbe N, Shenoy AT, Reyes LF, Dube PH, Restrepo MI, Orihuela CJ.

Infect Immun. 2016 Apr 22;84(5):1457-69. doi: 10.1128/IAI.00007-16. Print 2016 May.

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