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Items: 16

1.

Reinforcing mitochondrial functions in aging brain: An insight into Parkinson's disease therapeutics.

Chandra G, Shenoi RA, Anand R, Rajamma U, Mohanakumar KP.

J Chem Neuroanat. 2019 Jan;95:29-42. doi: 10.1016/j.jchemneu.2017.12.004. Epub 2017 Dec 18. Review.

PMID:
29269015
2.

A Polymer Therapeutic Having Universal Heparin Reversal Activity: Molecular Design and Functional Mechanism.

Kalathottukaren MT, Abbina S, Yu K, Shenoi RA, Creagh AL, Haynes C, Kizhakkedathu JN.

Biomacromolecules. 2017 Oct 9;18(10):3343-3358. doi: 10.1021/acs.biomac.7b00994. Epub 2017 Sep 19.

PMID:
28880550
3.

Nontransformed and Cancer Cells Can Utilize Different Endocytic Pathways To Internalize Dendritic Nanoparticle Variants: Implications on Nanocarrier Design.

Wong NKY, Shenoi RA, Abbina S, Chafeeva I, Kizhakkedathu JN, Khan MK.

Biomacromolecules. 2017 Aug 14;18(8):2427-2438. doi: 10.1021/acs.biomac.7b00590. Epub 2017 Jul 17.

PMID:
28655275
4.

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA.

Kalathottukaren MT, Abraham L, Kapopara PR, Lai BF, Shenoi RA, Rosell FI, Conway EM, Pryzdial EL, Morrissey JH, Haynes CA, Kizhakkedathu JN.

Blood. 2017 Mar 9;129(10):1368-1379. doi: 10.1182/blood-2016-10-747915. Epub 2016 Dec 29.

5.

In Vivo Biological Evaluation of High Molecular Weight Multifunctional Acid-Degradable Polymeric Drug Carriers with Structurally Different Ketals.

Shenoi RA, Abbina S, Kizhakkedathu JN.

Biomacromolecules. 2016 Nov 14;17(11):3683-3693. Epub 2016 Oct 27.

PMID:
27750017
6.

Design Considerations for Developing Hyperbranched Polyglycerol Nanoparticles as Systemic Drug Carriers.

Wong NK, Misri R, Shenoi RA, Chafeeva I, Kizhakkedathu JN, Khan MK.

J Biomed Nanotechnol. 2016 May;12(5):1089-100.

PMID:
27305828
7.

Investigation of hydrophobically derivatized hyperbranched polyglycerol with PEGylated shell as a nanocarrier for systemic delivery of chemotherapeutics.

Misri R, Wong NK, Shenoi RA, Lum CM, Chafeeva I, Toth K, Rustum Y, Kizhakkedathu JN, Khan MK.

Nanomedicine. 2015 Oct;11(7):1785-95. doi: 10.1016/j.nano.2015.04.016. Epub 2015 May 14.

PMID:
25981338
8.

Conjugation of aurein 2.2 to HPG yields an antimicrobial with better properties.

Kumar P, Shenoi RA, Lai BF, Nguyen M, Kizhakkedathu JN, Straus SK.

Biomacromolecules. 2015 Mar 9;16(3):913-23. doi: 10.1021/bm5018244. Epub 2015 Feb 20.

PMID:
25664972
9.

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.

Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN.

Sci Transl Med. 2014 Oct 29;6(260):260ra150. doi: 10.1126/scitranslmed.3009427. Epub 2014 Oct 29.

10.

Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis.

Travers RJ, Shenoi RA, Kalathottukaren MT, Kizhakkedathu JN, Morrissey JH.

Blood. 2014 Nov 20;124(22):3183-90. doi: 10.1182/blood-2014-05-577932. Epub 2014 Sep 8.

11.

Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo.

Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN.

ACS Nano. 2013 Dec 23;7(12):10704-16. doi: 10.1021/nn4035074. Epub 2013 Nov 25.

PMID:
24256569
12.

Biodegradable polyglycerols with randomly distributed ketal groups as multi-functional drug delivery systems.

Shenoi RA, Lai BF, Imran ul-haq M, Brooks DE, Kizhakkedathu JN.

Biomaterials. 2013 Aug;34(25):6068-81. doi: 10.1016/j.biomaterials.2013.04.043. Epub 2013 May 17.

PMID:
23688604
13.

Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators.

Shenoi RA, Lai BF, Kizhakkedathu JN.

Biomacromolecules. 2012 Oct 8;13(10):3018-30. doi: 10.1021/bm300959h. Epub 2012 Sep 5.

PMID:
22920950
14.

Branched multifunctional polyether polyketals: variation of ketal group structure enables unprecedented control over polymer degradation in solution and within cells.

Shenoi RA, Narayanannair JK, Hamilton JL, Lai BF, Horte S, Kainthan RK, Varghese JP, Rajeev KG, Manoharan M, Kizhakkedathu JN.

J Am Chem Soc. 2012 Sep 12;134(36):14945-57. doi: 10.1021/ja305080f. Epub 2012 Aug 30.

PMID:
22906064
15.

Development of soluble ester-linked aldehyde polymers for proteomics.

Beaudette P, Rossi NA, Huesgen PF, Yu X, Shenoi RA, Doucet A, Overall CM, Kizhakkedathu JN.

Anal Chem. 2011 Sep 1;83(17):6500-10. doi: 10.1021/ac200419p. Epub 2011 Aug 11.

PMID:
21774540
16.

High molecular weight polyglycerol-based multivalent mannose conjugates.

Kizhakkedathu JN, Creagh AL, Shenoi RA, Rossi NA, Brooks DE, Chan T, Lam J, Dandepally SR, Haynes CA.

Biomacromolecules. 2010 Oct 11;11(10):2567-75. doi: 10.1021/bm1004788.

PMID:
20804173

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