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Performance of next-generation sequencing in the detection of large exon deletion in patients of haemophilia A.

He X, Xiong Z, Shen N, Lu Y, Wang X.

Haemophilia. 2018 Jul 13. doi: 10.1111/hae.13584. [Epub ahead of print] No abstract available.


Allelic phenotype values: a model for genotype-based phenotype prediction in phenylketonuria.

Garbade SF, Shen N, Himmelreich N, Haas D, Trefz FK, Hoffmann GF, Burgard P, Blau N.

Genet Med. 2018 Jul 12. doi: 10.1038/s41436-018-0081-x. [Epub ahead of print]


Enhanced Bone Metastases in Skeletally Immature Mice.

Haley HR, Shen N, Qyli T, Buschhaus JM, Pirone M, Luker KE, Luker GD.

Tomography. 2018 Jun;4(2):84-93. doi: 10.18383/j.tom.2018.00010.


Hepatology highlights.

Russo N, Brown RS Jr, Shen NT, Pisa JF, Mukewar S, Tafesh ZH, Rosenblatt R, Schwartz RE, Gupta V, Novikov A, Cohen-Mekelburg S.

Hepatology. 2018 Jul;68(1):1-3. doi: 10.1002/hep.30117. No abstract available.


Geranylgeranyl diphosphate synthase (GGPPS) regulates NAFLD/fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat-diet conditions.

Liu J, Jiang S, Zhao Y, Sun Q, Zhang J, Shen D, Wu J, Shen N, Fu X, Sun X, Yu D, Chen J, He J, Shi T, Ding Y, Fang L, Xue B, Li C.

J Pathol. 2018 Jul 3. doi: 10.1002/path.5131. [Epub ahead of print]


Severe Obstructive Sleep Apnea is Associated with Alterations in the Nasal Microbiome and Increase in Inflammation.

Wu BG, Sulaiman I, Wang J, Shen N, Clemente JC, Li Y, Laumbach RJ, Lu SE, Udasin I, Le-Hoang O, Perez A, Alimokhtari S, Black K, Plietz M, Twumasi A, Sanders H, Melacha P, Kapoor B, Scaglione BD, Wang A, Blazoski C, Weiden MD, Rapoport DM, Harrison D, Chitkara N, Vicente E, Marin JM, Sunderram J, Ayappa I, Segal LN.

Am J Respir Crit Care Med. 2018 Jul 3. doi: 10.1164/rccm.201801-0119OC. [Epub ahead of print]


Identification of pathways and genes associated with synovitis in osteoarthritis using bioinformatics analyses.

Huang H, Zheng J, Shen N, Wang G, Zhou G, Fang Y, Lin J, Zhao J.

Sci Rep. 2018 Jul 3;8(1):10050. doi: 10.1038/s41598-018-28280-6.


Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production.

Wang Z, Yin W, Zhu L, Li J, Yao Y, Chen F, Sun M, Zhang J, Shen N, Song Y, Chang X.

Immunity. 2018 Jun 21. pii: S1074-7613(18)30244-9. doi: 10.1016/j.immuni.2018.05.008. [Epub ahead of print]


Reducing the toxicity of amphotericin B by encapsulation using methoxy poly(ethylene glycol)-b-poly(l-glutamic acid-co-l-phenylalanine).

Yang C, Xue B, Song W, Kan B, Zhang D, Yu H, Shen N, Li X, Tang Z, Chen X.

Biomater Sci. 2018 Jun 27. doi: 10.1039/c8bm00506k. [Epub ahead of print]


Responses of the native species Sparganium angustifolium and the invasive species Egeria densa to warming and interspecific competition.

Yu H, Shen N, Yu S, Yu D, Liu C.

PLoS One. 2018 Jun 20;13(6):e0199478. doi: 10.1371/journal.pone.0199478. eCollection 2018.


A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Patel Z, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Martin J, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA, Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA, Alarcón-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, Harley JB, Kottyan LC.

Hum Mol Genet. 2018 Apr 18. doi: 10.1093/hmg/ddy140. [Epub ahead of print]


Controlling optical polarization conversion with Ge2Sb2Te5-based phase-change dielectric metamaterials.

Zhu W, Yang R, Fan Y, Fu Q, Wu H, Zhang P, Shen NH, Zhang F.

Nanoscale. 2018 Jul 5;10(25):12054-12061. doi: 10.1039/c8nr02587h.


Molecular characterization and allergenicity potential of triosephosphate isomerase from Sarcoptes scabiei.

He R, Zhang H, Shen N, Guo C, Ren Y, Xie Y, Gu X, Lai W, Peng X, Yang G.

Vet Parasitol. 2018 Jun 15;257:40-47. doi: 10.1016/j.vetpar.2018.05.016. Epub 2018 May 28.


Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery.

Cui J, Li Q, Luo M, Zhong Z, Zhou S, Jiang L, Shen N, Geng Z, Cheng H, Meng L, Yi S, Sun H, Wu F, Zhu Z, Zou P, You Y, Guo AY, Zhu X.

Oncoimmunology. 2018 Mar 26;7(7):e1448330. doi: 10.1080/2162402X.2018.1448330. eCollection 2018.


Serodiagnostic Potential of Alpha-Enolase From Sarcoptes scabiei and Its Possible Role in Host-Mite Interactions.

Xu J, Huang X, Dong X, Ren Y, Wu M, Shen N, Xie Y, Gu X, Lai W, Jing B, Peng X, Yang G.

Front Microbiol. 2018 May 25;9:1024. doi: 10.3389/fmicb.2018.01024. eCollection 2018.


Airway Microbiota Is Associated with Up-Regulation of the PI3K Pathway in Lung Cancer.

Tsay JJ, Wu BG, Badri MH, Clemente JC, Shen N, Meyn P, Li Y, Yie TA, Lhakhang T, Olsen E, Murthy V, Michaud G, Sulaiman I, Tsirigos A, Heguy A, Pass H, Weiden MD, Rom WN, Sterman DH, Bonneau R, Blaser MJ, Segal LN.

Am J Respir Crit Care Med. 2018 Jun 4. doi: 10.1164/rccm.201710-2118OC. [Epub ahead of print]


Elevated IFIT3 Contributes to Abnormal Overactive cGAS-STING Signaling in Human Systemic Lupus Erythematosus Monocytes.

Wang J, Dai M, Cui Y, Hou G, Deng J, Gao X, Liao Z, Liu Y, Meng Y, Wu L, Yao C, Wang Y, Qian J, Guo Q, Ding H, Qu B, Shen N.

Arthritis Rheumatol. 2018 May 27. doi: 10.1002/art.40576. [Epub ahead of print]


Cost Effectiveness of Gastric Cancer Screening According to Race and Ethnicity.

Saumoy M, Schneider Y, Shen N, Kahaleh M, Sharaiha RZ, Shah SC.

Gastroenterology. 2018 May 17. pii: S0016-5085(18)34546-3. doi: 10.1053/j.gastro.2018.05.026. [Epub ahead of print]


FVIII p.Arg1800His mutation is associated with mild/moderate hemophilia A in Chinese population.

Wang X, Lyu Y, Shen N, Hu Q, Lu Y.

Int J Lab Hematol. 2018 May 13. doi: 10.1111/ijlh.12851. [Epub ahead of print] No abstract available.


TRIM24 siRNA induced cell apoptosis and reduced cell viability in human nasopharyngeal carcinoma cells.

Wang P, Shen N, Liu D, Ning X, Wu D, Huang X.

Mol Med Rep. 2018 Jul;18(1):369-376. doi: 10.3892/mmr.2018.8946. Epub 2018 May 2.


Hydrogen production from a thermophilic alkaline waste activated sludge fermenter: Effects of solid retention time (SRT).

Chen Y, Xiao K, Shen N, Zeng RJ, Zhou Y.

Chemosphere. 2018 Sep;206:101-106. doi: 10.1016/j.chemosphere.2018.04.170. Epub 2018 May 1.


Supramolecular Organization of [TeCl6]2- with Ionic Liquid Cations: Studies on the Electrical Conductivity and Luminescent Properties.

Shen NN, Cai ML, Song Y, Wang ZP, Huang FQ, Li JR, Huang XY.

Inorg Chem. 2018 May 7;57(9):5282-5291. doi: 10.1021/acs.inorgchem.8b00297. Epub 2018 Apr 24.


Hepatology Highlights.

Cohen-Mekelburg S, Schwartz RE, Rosenblatt R, Brown RS Jr, Tafesh ZH, Tow C, Russo N, Schneider Y, Gupta V, Mukewar S, Shen NT, Novikov A.

Hepatology. 2018 May;67(5):1647-1650. doi: 10.1002/hep.29894. No abstract available.


HDL-AuNPs-BMS Nanoparticle Conjugates as Molecularly Targeted Therapy for Leukemia.

Shen N, Yan F, Pang J, Gao Z, Al-Kali A, Haynes CL, Litzow MR, Liu S.

ACS Appl Mater Interfaces. 2018 May 2;10(17):14454-14462. doi: 10.1021/acsami.8b01696. Epub 2018 Apr 18.


Cost Effectiveness of Early Insertion of Transjugular Intrahepatic Portosystemic Shunts for Recurrent Ascites.

Shen NT, Schneider Y, Congly SE, Rosenblatt RE, Namn Y, Fortune BE, Jesudian A, Brown RS Jr.

Clin Gastroenterol Hepatol. 2018 Mar 30. pii: S1542-3565(18)30324-0. doi: 10.1016/j.cgh.2018.03.027. [Epub ahead of print]


Divergence in DNA Specificity among Paralogous Transcription Factors Contributes to Their Differential In Vivo Binding.

Shen N, Zhao J, Schipper JL, Zhang Y, Bepler T, Leehr D, Bradley J, Horton J, Lapp H, Gordan R.

Cell Syst. 2018 Apr 25;6(4):470-483.e8. doi: 10.1016/j.cels.2018.02.009. Epub 2018 Mar 28.


MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus.

Geng L, Tang X, Zhou K, Wang D, Wang S, Yao G, Chen W, Gao X, Chen W, Shi S, Shen N, Feng X, Sun L.

Cell Mol Immunol. 2018 Mar 26. doi: 10.1038/cmi.2018.1. [Epub ahead of print]


Inhibiting core fucosylation attenuates glucose-induced peritoneal fibrosis in rats.

Li L, Shen N, Wang N, Wang W, Tang Q, Du X, Carrero JJ, Wang K, Deng Y, Li Z, Lin H, Wu T.

Kidney Int. 2018 Jun;93(6):1384-1396. doi: 10.1016/j.kint.2017.12.023. Epub 2018 Mar 20.


Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients.

Liu M, Guo Q, Wu C, Sterlin D, Goswami S, Zhang Y, Li T, Bao C, Shen N, Fu Q, Zhang X.

Cell Mol Immunol. 2018 Mar 21. doi: 10.1038/s41423-018-0010-6. [Epub ahead of print]


Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.

Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, Zhang X, Yu T, Gan S, Dai D, Luo X, Lu Q, Mao C, Zhang Y, Shen N, Li B, Huang M, Zhu X, Jin J, Cheng X, Sun SC, Xiao Y.

Nat Commun. 2018 Mar 19;9(1):1136. doi: 10.1038/s41467-018-03530-3.


Targeting epigenetic pathway with gold nanoparticles for acute myeloid leukemia therapy.

Deng R, Shen N, Yang Y, Yu H, Xu S, Yang YW, Liu S, Meguellati K, Yan F.

Biomaterials. 2018 Jun;167:80-90. doi: 10.1016/j.biomaterials.2018.03.013. Epub 2018 Mar 14.


[Killing effect of Huaier combined with DC-CIK on nude mice bearing colon cancer HT29 stem cells in vivo].

Sun WW, Dou JX, Zhang L, Qiao LK, Shen N, Gao WY.

Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):168-173. doi: 10.19540/j.cnki.cjcmm.20161222.055. Chinese.


Gut microbiota dysbiosis is associated with Henoch-Schönlein Purpura in children.

Wang X, Zhang L, Wang Y, Liu X, Zhang H, Liu Y, Shen N, Yang J, Gai Z.

Int Immunopharmacol. 2018 May;58:1-8. doi: 10.1016/j.intimp.2018.03.003. Epub 2018 Mar 8.


Effects of ulinastatin on inflammatory response and cognitive function after hip arthroplasty for the elderly patients with femoral neck fracture.

Ren KW, Shen N, Tang JL, Nong LM, Gu YQ.

Eur Rev Med Pharmacol Sci. 2018 Feb;22(4):1126-1132. doi: 10.26355/eurrev_201802_14401.


Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity.

Ryan AJ, Kearney CJ, Shen N, Khan U, Kelly AG, Probst C, Brauchle E, Biccai S, Garciarena CD, Vega-Mayoral V, Loskill P, Kerrigan SW, Kelly DJ, Schenke-Layland K, Coleman JN, O'Brien FJ.

Adv Mater. 2018 Apr;30(15):e1706442. doi: 10.1002/adma.201706442. Epub 2018 Mar 5.


Mutation spectrum of hyperphenylalaninemia candidate genes and the genotype-phenotype correlation in the Chinese population.

Wang R, Shen N, Ye J, Han L, Qiu W, Zhang H, Liang L, Sun Y, Fan Y, Wang L, Wang Y, Gong Z, Liu H, Wang J, Yan H, Blau N, Gu X, Yu Y.

Clin Chim Acta. 2018 Jun;481:132-138. doi: 10.1016/j.cca.2018.02.035. Epub 2018 Feb 28.


Endotracheal and Endobronchial Metastases of Small Cell Lung Cancer.

Lu M, Zhu X, Shen N.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1628-1629. doi: 10.1164/rccm.201708-1773IM. No abstract available.


Complete Genome Sequence of Actinobacillus succinogenes GXAS137, a Highly Efficient Producer of Succinic Acid.

Zhang H, Shen N, Qin Y, Zhu J, Li Y, Wu J, Jiang MG.

Genome Announc. 2018 Feb 22;6(8). pii: e01562-17. doi: 10.1128/genomeA.01562-17.


Novel hereditary spherocytosis-associated splice site mutation in the ANK1 gene caused by parental gonosomal mosaicism.

Wang X, Shen N, Huang M, Lu Y, Hu Q.

Haematologica. 2018 May;103(5):e219-e222. doi: 10.3324/haematol.2017.186551. Epub 2018 Feb 15. No abstract available.


Evaluating the diagnostic accuracy of the Xpert MTB/RIF assay on bronchoalveolar lavage fluid: A retrospective study.

Lu Y, Zhu Y, Shen N, Tian L, Sun Z.

Int J Infect Dis. 2018 Jun;71:14-19. doi: 10.1016/j.ijid.2018.01.030. Epub 2018 Feb 8.


Antihypoxic activities of constituents from Arenaria kansuensis.

Cui Y, Tao Y, Jiang L, Shen N, Wang S, Wen H, Liu Z.

Phytomedicine. 2018 Jan 1;38:175-182. doi: 10.1016/j.phymed.2017.12.008. Epub 2017 Dec 8.


Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway.

Chen M, Lu X, Lu C, Shen N, Jiang Y, Chen M, Wu H.

Arthritis Res Ther. 2018 Feb 7;20(1):20. doi: 10.1186/s13075-018-1512-4.


Efficient degradation of 2,4-dichlorophenol in aqueous solution by peroxymonosulfate activated with magnetic spinel FeCo2O4 nanoparticles.

Zhou R, Zhao J, Shen N, Ma T, Su Y, Ren H.

Chemosphere. 2018 Apr;197:670-679. doi: 10.1016/j.chemosphere.2018.01.079. Epub 2018 Jan 19.


Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.

Chang J, Zhong R, Tian J, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Zhu Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Wu T, Wu C, Miao X, Lin D.

Nat Genet. 2018 Mar;50(3):338-343. doi: 10.1038/s41588-018-0045-8. Epub 2018 Jan 29.


Genipin ameliorates diet-induced obesity via promoting lipid mobilization and browning of white adipose tissue in rats.

Guan L, Gong D, Yang S, Shen N, Zhang S, Li Y, Wu Q, Yuan B, Sun Y, Dai N, Zhu L, Zou Y.

Phytother Res. 2018 Apr;32(4):723-732. doi: 10.1002/ptr.6022. Epub 2018 Jan 29.


EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.

Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W.

Int J Ophthalmol. 2018 Jan 18;11(1):18-24. doi: 10.18240/ijo.2018.01.04. eCollection 2018.


An ANK1 IVS3-2A>C mutation causes exon 4 skipping in two patients from a Chinese family with hereditary spherocytosis.

Wang X, Mao L, Shen N, Peng J, Zhu Y, Hu Q, Lu Y.

Oncotarget. 2017 Dec 5;8(68):113282-113286. doi: 10.18632/oncotarget.22936. eCollection 2017 Dec 22.


MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms.

Do T, Tan R, Bennett M, Medvedovic M, Grom AA, Shen N, Thornton S, Schulert GS.

J Leukoc Biol. 2018 Jan;103(1):71-85. doi: 10.1002/JLB.2A0317-107R. Epub 2017 Dec 29.


Pterostilbene inhibits reactive oxygen species production and apoptosis in primary spinal cord neurons by activating autophagy via the mechanistic target of rapamycin signaling pathway.

He JL, Dong XH, Li ZH, Wang XY, Fu ZA, Shen N.

Mol Med Rep. 2018 Mar;17(3):4406-4414. doi: 10.3892/mmr.2018.8412. Epub 2018 Jan 9.

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