Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46

1.

Removal of heavy oil using rhinoceros beetle, Oryctes rhinoceros.

Shen MW, Yan CY, Chen HC, Chen ST.

J Environ Manage. 2019 Aug 20;249:109418. doi: 10.1016/j.jenvman.2019.109418. [Epub ahead of print]

PMID:
31442910
2.

Suppression of WNK1-SPAK/OSR1 Attenuates Bone Cancer Pain by Regulating NKCC1 and KCC2.

Gao JL, Peng K, Shen MW, Hou YH, Qian XB, Meng XW, Ji FH, Wang LN, Yang JP.

J Pain. 2019 May 11. pii: S1526-5900(18)30703-X. doi: 10.1016/j.jpain.2019.05.005. [Epub ahead of print]

PMID:
31085334
3.

Author Correction: Predictable and precise template-free CRISPR editing of pathogenic variants.

Shen MW, Arbab M, Hsu JY, Worstell D, Culbertson SJ, Krabbe O, Cassa CA, Liu DR, Gifford DK, Sherwood RI.

Nature. 2019 Mar;567(7746):E1-E2. doi: 10.1038/s41586-019-0938-4.

PMID:
30765887
4.

Predictable and precise template-free CRISPR editing of pathogenic variants.

Shen MW, Arbab M, Hsu JY, Worstell D, Culbertson SJ, Krabbe O, Cassa CA, Liu DR, Gifford DK, Sherwood RI.

Nature. 2018 Nov;563(7733):646-651. doi: 10.1038/s41586-018-0686-x. Epub 2018 Nov 7. Erratum in: Nature. 2019 Mar;567(7746):E1-E2.

5.

Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.

Lee KL, Ambler CM, Anderson DR, Boscoe BP, Bree AG, Brodfuehrer JI, Chang JS, Choi C, Chung S, Curran KJ, Day JE, Dehnhardt CM, Dower K, Drozda SE, Frisbie RK, Gavrin LK, Goldberg JA, Han S, Hegen M, Hepworth D, Hope HR, Kamtekar S, Kilty IC, Lee A, Lin LL, Lovering FE, Lowe MD, Mathias JP, Morgan HM, Murphy EA, Papaioannou N, Patny A, Pierce BS, Rao VR, Saiah E, Samardjiev IJ, Samas BM, Shen MWH, Shin JH, Soutter HH, Strohbach JW, Symanowicz PT, Thomason JR, Trzupek JD, Vargas R, Vincent F, Yan J, Zapf CW, Wright SW.

J Med Chem. 2017 Jul 13;60(13):5521-5542. doi: 10.1021/acs.jmedchem.7b00231. Epub 2017 Jun 14.

PMID:
28498658
6.

Assembly of long error-prone reads using de Bruijn graphs.

Lin Y, Yuan J, Kolmogorov M, Shen MW, Chaisson M, Pevzner PA.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8396-E8405. doi: 10.1073/pnas.1604560113. Epub 2016 Dec 12.

7.

Urinary Imaging Findings in Young Infants With Bacteremic Urinary Tract Infection.

Chang PW, Abidari JM, Shen MW, Greenhow TL, Bendel-Stenzel M, Roman HK, Biondi EA, Schroeder AR; PRIS Bacteremic UTI Investigators.

Hosp Pediatr. 2016 Nov;6(11):647-652. Epub 2016 Oct 5.

8.

Measuring Handoffs: Can We Improve the Transition of Hospitalized Children?

Quinonez RA, Shen MW.

Pediatrics. 2016 Aug;138(2). pii: e20161546. doi: 10.1542/peds.2016-1546. No abstract available.

9.

Look Who's Talking: Comparing Perceptions Versus Direct Observations in Family-Centered Rounds.

Pickel S, Shen MW, Hovinga C.

Hosp Pediatr. 2016 Jul;6(7):387-93. doi: 10.1542/hpeds.2015-0136. Epub 2016 Jun 9.

10.

Authors' Response.

Schroeder AR, Chang PW, Shen MW, Biondi EA, Greenhow TL.

Pediatrics. 2015 Oct;136(4):e1167-8. doi: 10.1542/peds.2015-2606B. No abstract available.

11.

Bacteraemic urinary tract infection: management and outcomes in young infants.

Schroeder AR, Shen MW, Biondi EA, Bendel-Stenzel M, Chen CN, French J, Lee V, Evans RC, Jerardi KE, Mischler M, Wood KE, Chang PW, Roman HK, Greenhow TL.

Arch Dis Child. 2016 Feb;101(2):125-30. doi: 10.1136/archdischild-2014-307997. Epub 2015 Jul 15.

PMID:
26177657
12.

Diagnostic accuracy of the urinalysis for urinary tract infection in infants <3 months of age.

Schroeder AR, Chang PW, Shen MW, Biondi EA, Greenhow TL.

Pediatrics. 2015 Jun;135(6):965-71. doi: 10.1542/peds.2015-0012.

13.

Antibiotic and Diagnostic Discordance Between ED Physicians and Hospitalists for Pediatric Respiratory Illness.

Coon ER, Maloney CG, Shen MW.

Hosp Pediatr. 2015 Mar;5(3):111-8. doi: 10.1542/hpeds.2014-0110.

14.

Summary of STARNet: Seamless Transitions and (Re)admissions Network.

Auger KA, Simon TD, Cooperberg D, Gay J, Kuo DZ, Saysana M, Stille CJ, Fisher ES, Wallace S, Berry J, Coghlin D, Jhaveri V, Kairys S, Logsdon T, Shaikh U, Srivastava R, Starmer AJ, Wilkins V, Shen MW.

Pediatrics. 2015 Jan;135(1):164-75. doi: 10.1542/peds.2014-1887. Epub 2014 Dec 8.

15.

Pediatric hospitalists collaborate to improve timeliness of discharge communication.

Shen MW, Hershey D, Bergert L, Mallory L, Fisher ES, Cooperberg D.

Hosp Pediatr. 2013 Jul;3(3):258-65.

16.

Quality improvement research in pediatric hospital medicine and the role of the Pediatric Research in Inpatient Settings (PRIS) network.

Simon TD, Starmer AJ, Conway PH, Landrigan CP, Shah SS, Shen MW, Sectish TC, Spector ND, Tieder JS, Srivastava R, Willis LE, Wilson KM.

Acad Pediatr. 2013 Nov-Dec;13(6 Suppl):S54-60. doi: 10.1016/j.acap.2013.04.006. Review.

PMID:
24268086
17.

Development and characterization of a vector set with regulated promoters for systematic metabolic engineering in Saccharomyces cerevisiae.

Shen MW, Fang F, Sandmeyer S, Da Silva NA.

Yeast. 2012 Dec;29(12):495-503. doi: 10.1002/yea.2930. Epub 2012 Nov 19.

18.

Quality measures in pediatric hospital medicine: Moneyball or looking for Fabio?

Shen MW, Percelay J.

Hosp Pediatr. 2012 Jul;2(3):121-5. No abstract available.

19.

Enhanced arsenate uptake in Saccharomyces cerevisiae overexpressing the Pho84 phosphate transporter.

Shen MW, Shah D, Chen W, Da Silva N.

Biotechnol Prog. 2012 May-Jun;28(3):654-61. doi: 10.1002/btpr.1531. Epub 2012 May 25.

PMID:
22628173
20.

The cPLA2α inhibitor efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid.

Nickerson-Nutter CL, Goodwin D, Shen MW, Damphousse C, Duan W, Samad TA, McKew JC, Lee KL, Zaleska MM, Mollova N, Clark JD.

Neuropharmacology. 2011 Mar;60(4):633-41. doi: 10.1016/j.neuropharm.2010.11.025. Epub 2010 Dec 10.

PMID:
21146550
21.

A vector set for systematic metabolic engineering in Saccharomyces cerevisiae.

Fang F, Salmon K, Shen MW, Aeling KA, Ito E, Irwin B, Tran UP, Hatfield GW, Da Silva NA, Sandmeyer S.

Yeast. 2011 Feb;28(2):123-36. doi: 10.1002/yea.1824. Epub 2010 Oct 8.

22.

Enhanced arsenic accumulation in Saccharomyces cerevisiae overexpressing transporters Fps1p or Hxt7p.

Shah D, Shen MW, Chen W, Da Silva NA.

J Biotechnol. 2010 Oct 1;150(1):101-7. doi: 10.1016/j.jbiotec.2010.07.012. Epub 2010 Jul 16.

PMID:
20638426
23.

Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.

Kirincich SJ, Xiang J, Green N, Tam S, Yang HY, Shim J, Shen MW, Clark JD, McKew JC.

Bioorg Med Chem. 2009 Jul 1;17(13):4383-405. doi: 10.1016/j.bmc.2009.05.027. Epub 2009 May 18.

PMID:
19482480
24.

Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.

Chen L, Wang W, Lee KL, Shen MW, Murphy EA, Zhang W, Xu X, Tam S, Nickerson-Nutter C, Goodwin DG, Clark JD, McKew JC.

J Med Chem. 2009 Feb 26;52(4):1156-71. doi: 10.1021/jm8009876.

PMID:
19178292
25.

Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses.

Marusic S, Thakker P, Pelker JW, Stedman NL, Lee KL, McKew JC, Han L, Xu X, Wolf SF, Borey AJ, Cui J, Shen MW, Donahue F, Hassan-Zahraee M, Leach MW, Shimizu T, Clark JD.

J Neuroimmunol. 2008 Nov 15;204(1-2):29-37. doi: 10.1016/j.jneuroim.2008.08.012.

PMID:
18829119
26.

Thermodynamic characterization of cytosolic phospholipase A2 alpha inhibitors.

Ramarao MK, Shen MW, Murphy EA, Duan W, Zhao Y, McKew J, Lee KL, Thakker P, Behnke ML, Clark JD.

Anal Biochem. 2008 Dec 15;383(2):217-25. doi: 10.1016/j.ab.2008.08.025. Epub 2008 Aug 30.

PMID:
18801329
27.

Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.

McKew JC, Lee KL, Shen MW, Thakker P, Foley MA, Behnke ML, Hu B, Sum FW, Tam S, Hu Y, Chen L, Kirincich SJ, Michalak R, Thomason J, Ipek M, Wu K, Wooder L, Ramarao MK, Murphy EA, Goodwin DG, Albert L, Xu X, Donahue F, Ku MS, Keith J, Nickerson-Nutter CL, Abraham WM, Williams C, Hegen M, Clark JD.

J Med Chem. 2008 Jun 26;51(12):3388-413. doi: 10.1021/jm701467e. Epub 2008 May 23.

PMID:
18498150
28.

Diagnostic and therapeutic challenges of childhood brucellosis in a nonendemic country.

Shen MW.

Pediatrics. 2008 May;121(5):e1178-83. doi: 10.1542/peds.2007-1874. Erratum in: Pediatrics.2008 Jul;122(1): 228.

PMID:
18450861
29.

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy.

Lee KL, Behnke ML, Foley MA, Chen L, Wang W, Vargas R, Nunez J, Tam S, Mollova N, Xu X, Shen MW, Ramarao MK, Goodwin DG, Nickerson-Nutter CL, Abraham WM, Williams C, Clark JD, McKew JC.

Bioorg Med Chem. 2008 Feb 1;16(3):1345-58. Epub 2007 Oct 22.

PMID:
17998165
30.

Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha.

Lee KL, Foley MA, Chen L, Behnke ML, Lovering FE, Kirincich SJ, Wang W, Shim J, Tam S, Shen MW, Khor S, Xu X, Goodwin DG, Ramarao MK, Nickerson-Nutter C, Donahue F, Ku MS, Clark JD, McKew JC.

J Med Chem. 2007 Mar 22;50(6):1380-400. Epub 2007 Feb 17.

PMID:
17305324
31.

Chiral N-salicylidene vanadyl carboxylate-catalyzed enantioselective aerobic oxidation of alpha-hydroxy esters and amides.

Weng SS, Shen MW, Kao JQ, Munot YS, Chen CT.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3522-7. Epub 2006 Feb 24.

32.

Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.

McKew JC, Foley MA, Thakker P, Behnke ML, Lovering FE, Sum FW, Tam S, Wu K, Shen MW, Zhang W, Gonzalez M, Liu S, Mahadevan A, Sard H, Khor SP, Clark JD.

J Med Chem. 2006 Jan 12;49(1):135-58.

PMID:
16392799
33.

Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.

Marusic S, Leach MW, Pelker JW, Azoitei ML, Uozumi N, Cui J, Shen MW, DeClercq CM, Miyashiro JS, Carito BA, Thakker P, Simmons DL, Leonard JP, Shimizu T, Clark JD.

J Exp Med. 2005 Sep 19;202(6):841-51.

34.

[Observation of the cognition and the velocities of blood in the brain in cerebral arteriosclerosis and infarct patients].

Guo ZJ, Shen MW, Jin LY.

Space Med Med Eng (Beijing). 2005 Jun;18(3):170-2. Chinese.

PMID:
16161271
35.

A fluorescence-based assay for fatty acid amide hydrolase compatible with high-throughput screening.

Ramarao MK, Murphy EA, Shen MW, Wang Y, Bushell KN, Huang N, Pan N, Williams C, Clark JD.

Anal Biochem. 2005 Aug 1;343(1):143-51.

PMID:
16018870
36.

[An event-related potential study the on information processing of binocular disparity in random-dot stereogram].

Shen MW, Wang R, Tang XW, Zhu HY.

Space Med Med Eng (Beijing). 2004 Apr;17(2):149-51. Chinese.

PMID:
15920836
37.

Estimation of apparent rate coefficients for phenanthrene and pentachlorophenol interacting with sediments.

Chen HL, Chen YX, Xu YT, Shen MW.

Environ Pollut. 2004 Sep;131(2):223-31.

PMID:
15234089
38.

Irreversible sorption of pentachlorophenol to sediments: experimental observations.

Chen YX, Chen HL, Xu YT, Shen MW.

Environ Int. 2004 Mar;30(1):31-7.

PMID:
14664862
39.

[Spatial and temporal characteristic of eye movement in human-computer interface design].

Shen MW, Feng CZ, Su H.

Space Med Med Eng (Beijing). 2003 Aug;16(4):304-6. Chinese.

PMID:
14594043
40.

[A study on visual search and selection of pull-down menu].

Shen MW, Tao R, Liu Y.

Space Med Med Eng (Beijing). 2003 Feb;16(1):72-4. Chinese.

PMID:
12728964
41.

[Study on sensitivity of event-related EEG sychronization and desychronization visual memory load].

Shen MW, Yi YJ, Xu Q.

Space Med Med Eng (Beijing). 2002 Dec;15(6):445-7. Chinese.

PMID:
12622087
42.

A flow cytometric comparison of DNA content and glutathione levels in hepatocytes of English sole (Parophyrs vetulus) from areas of differing water quality.

Jenner NK, Ostrander GK, Kavanagh TJ, Livesey JC, Shen MW, Kim SC, Holmes EH.

Arch Environ Contam Toxicol. 1990 Nov-Dec;19(6):807-15.

PMID:
2256702
45.
46.

Supplemental Content

Support Center