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Items: 1 to 50 of 128

1.

NSD2 is a conserved driver of metastatic prostate cancer progression.

Aytes A, Giacobbe A, Mitrofanova A, Ruggero K, Cyrta J, Arriaga J, Palomero L, Farran-Matas S, Rubin MA, Shen MM, Califano A, Abate-Shen C.

Nat Commun. 2018 Dec 5;9(1):5201. doi: 10.1038/s41467-018-07511-4.

2.

Prostate Cancer Research at the Crossroads.

Shen MM, Rubin MA.

Cold Spring Harb Perspect Med. 2018 Oct 22. pii: a036277. doi: 10.1101/cshperspect.a036277. [Epub ahead of print] No abstract available.

PMID:
30348836
3.

Prostate Stem Cells and Cancer Stem Cells.

Li JJ, Shen MM.

Cold Spring Harb Perspect Med. 2018 Oct 5. pii: a030395. doi: 10.1101/cshperspect.a030395. [Epub ahead of print]

PMID:
30291148
4.

Comparison of dynamic change of egg selenium deposition after feeding sodium selenite or selenium-enriched yeast.

Lu J, Qu L, Shen MM, Hu YP, Guo J, Dou TC, Wang KH.

Poult Sci. 2018 Sep 1;97(9):3102-3108. doi: 10.3382/ps/pey161.

PMID:
29788509
5.

Lineage Plasticity in Cancer Progression and Treatment.

Le Magnen C, Shen MM, Abate-Shen C.

Annu Rev Cancer Biol. 2018 Mar;2:271-289. doi: 10.1146/annurev-cancerbio-030617-050224. Epub 2017 Dec 1.

PMID:
29756093
6.

Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.

Lee SH, Hu W, Matulay JT, Silva MV, Owczarek TB, Kim K, Chua CW, Barlow LJ, Kandoth C, Williams AB, Bergren SK, Pietzak EJ, Anderson CB, Benson MC, Coleman JA, Taylor BS, Abate-Shen C, McKiernan JM, Al-Ahmadie H, Solit DB, Shen MM.

Cell. 2018 Apr 5;173(2):515-528.e17. doi: 10.1016/j.cell.2018.03.017.

PMID:
29625057
7.

Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation.

Chua CW, Epsi NJ, Leung EY, Xuan S, Lei M, Li BI, Bergren SK, Hibshoosh H, Mitrofanova A, Shen MM.

Elife. 2018 Jan 15;7. pii: e28768. doi: 10.7554/eLife.28768.

8.

Safety evaluation of daidzein in laying hens: Effects on laying performance, hatchability, egg quality, clinical blood parameters, and organ development.

Lu J, Qu L, Shen MM, Li SM, Dou TC, Hu YP, Wang KH.

Poult Sci. 2017 Jul 1;96(7):2098-2103. doi: 10.3382/ps/pew483.

PMID:
28520935
9.

A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue.

Talos F, Mitrofanova A, Bergren SK, Califano A, Shen MM.

Nat Commun. 2017 Apr 21;8:14662. doi: 10.1038/ncomms14662.

10.

Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer.

Zou M, Toivanen R, Mitrofanova A, Floch N, Hayati S, Sun Y, Le Magnen C, Chester D, Mostaghel EA, Califano A, Rubin MA, Shen MM, Abate-Shen C.

Cancer Discov. 2017 Jul;7(7):736-749. doi: 10.1158/2159-8290.CD-16-1174. Epub 2017 Apr 14.

11.

Prostate organogenesis: tissue induction, hormonal regulation and cell type specification.

Toivanen R, Shen MM.

Development. 2017 Apr 15;144(8):1382-1398. doi: 10.1242/dev.148270. Review.

12.

Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks.

Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM, Califano A.

Cell. 2016 Aug 11;166(4):1055. doi: 10.1016/j.cell.2016.07.036. No abstract available.

13.

Comparative lineage tracing reveals cellular preferences for prostate cancer initiation.

Wang ZA, Shen MM.

Mol Cell Oncol. 2015 Feb 25;2(3):e985548. doi: 10.4161/23723556.2014.985548. eCollection 2015 Jul-Sep.

14.

Basal Progenitors Contribute to Repair of the Prostate Epithelium Following Induced Luminal Anoikis.

Toivanen R, Mohan A, Shen MM.

Stem Cell Reports. 2016 May 10;6(5):660-667. doi: 10.1016/j.stemcr.2016.03.007. Epub 2016 Apr 21.

15.

Atg7 cooperates with Pten loss to drive prostate cancer tumor growth.

Santanam U, Banach-Petrosky W, Abate-Shen C, Shen MM, White E, DiPaola RS.

Genes Dev. 2016 Feb 15;30(4):399-407. doi: 10.1101/gad.274134.115.

16.

Illuminating the Properties of Prostate Luminal Progenitors.

Shen MM.

Cell Stem Cell. 2015 Dec 3;17(6):644-646. doi: 10.1016/j.stem.2015.11.018.

17.

Cell types of origin for prostate cancer.

Lee SH, Shen MM.

Curr Opin Cell Biol. 2015 Dec;37:35-41. doi: 10.1016/j.ceb.2015.10.002. Epub 2015 Nov 11. Review.

PMID:
26506127
18.

Cripto-1 ablation disrupts alveolar development in the mouse mammary gland through a progesterone receptor-mediated pathway.

Klauzinska M, McCurdy D, Rangel MC, Vaidyanath A, Castro NP, Shen MM, Gonzales M, Bertolette D, Bianco C, Callahan R, Salomon DS, Raafat A.

Am J Pathol. 2015 Nov;185(11):2907-22. doi: 10.1016/j.ajpath.2015.07.023. Epub 2015 Oct 1.

19.

ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm.

Ellis PS, Burbridge S, Soubes S, Ohyama K, Ben-Haim N, Chen C, Dale K, Shen MM, Constam D, Placzek M.

Development. 2015 Nov 15;142(22):3821-32. doi: 10.1242/dev.119628. Epub 2015 Sep 28.

20.

Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models.

Mitrofanova A, Aytes A, Zou M, Shen MM, Abate-Shen C, Califano A.

Cell Rep. 2015 Sep 29;12(12):2060-71. doi: 10.1016/j.celrep.2015.08.051. Epub 2015 Sep 17.

21.

Stem cells in genetically-engineered mouse models of prostate cancer.

Shibata M, Shen MM.

Endocr Relat Cancer. 2015 Dec;22(6):T199-208. doi: 10.1530/ERC-15-0367. Epub 2015 Sep 4. Review.

22.

Cancer: The complex seeds of metastasis.

Shen MM.

Nature. 2015 Apr 16;520(7547):298-9. doi: 10.1038/nature14377. Epub 2015 Apr 1. No abstract available.

PMID:
25830892
23.

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation.

Hogan MS, Parfitt DE, Zepeda-Mendoza CJ, Shen MM, Spector DL.

Cell Stem Cell. 2015 Mar 5;16(3):275-88. doi: 10.1016/j.stem.2015.02.001.

24.

[Differential expression of microRNA in chronic hepatitis B patients of pi-wei dampness-heat syndrome and of gan depression Pi deficiency syndrome: a primary research].

Wang EC, Zhang L, Liu HW, Guo YL, Zhang F, He CW, Shen MM, Feng QS.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Nov;34(11):1324-8. Chinese.

PMID:
25566623
25.

Characteristics of the saliva flow rates of minor salivary glands in healthy people.

Wang Z, Shen MM, Liu XJ, Si Y, Yu GY.

Arch Oral Biol. 2015 Mar;60(3):385-92. doi: 10.1016/j.archoralbio.2014.11.016. Epub 2014 Nov 29.

PMID:
25526622
26.

From blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesis.

Parfitt DE, Shen MM.

Philos Trans R Soc Lond B Biol Sci. 2014 Dec 5;369(1657). pii: 20130542. doi: 10.1098/rstb.2013.0542. Review.

27.

Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.

Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM, Califano A.

Cell. 2014 Oct 9;159(2):402-14. doi: 10.1016/j.cell.2014.09.021. Erratum in: Cell. 2016 Aug 11;166(4):1055.

28.

Single luminal epithelial progenitors can generate prostate organoids in culture.

Chua CW, Shibata M, Lei M, Toivanen R, Barlow LJ, Bergren SK, Badani KK, McKiernan JM, Benson MC, Hibshoosh H, Shen MM.

Nat Cell Biol. 2014 Oct;16(10):951-61, 1-4. doi: 10.1038/ncb3047. Epub 2014 Sep 21.

29.

Luminal cells are favored as the cell of origin for prostate cancer.

Wang ZA, Toivanen R, Bergren SK, Chambon P, Shen MM.

Cell Rep. 2014 Sep 11;8(5):1339-46. doi: 10.1016/j.celrep.2014.08.002. Epub 2014 Aug 28.

30.

Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.

Aytes A, Mitrofanova A, Lefebvre C, Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A, Pienta KJ, Shen MM, Califano A, Abate-Shen C.

Cancer Cell. 2014 May 12;25(5):638-651. doi: 10.1016/j.ccr.2014.03.017.

31.

SnapShot: Prostate cancer.

Barlow LJ, Shen MM.

Cancer Cell. 2013 Sep 9;24(3):400.e1. doi: 10.1016/j.ccr.2013.08.033. Review. No abstract available.

32.

A molecular signature predictive of indolent prostate cancer.

Irshad S, Bansal M, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Le Magnen C, Guarnieri P, Sumazin P, Benson MC, Shen MM, Califano A, Abate-Shen C.

Sci Transl Med. 2013 Sep 11;5(202):202ra122. doi: 10.1126/scitranslmed.3006408. Erratum in: Sci Transl Med. 2013 Sep 18;5(203):203er9.

33.

ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, LeKaye HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):E3506-15. doi: 10.1073/pnas.1303558110. Epub 2013 Aug 5.

34.

Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis.

Kruithof-de Julio M, Shibata M, Desai N, Reynon M, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM.

Dev Dyn. 2013 Oct;242(10):1160-71. doi: 10.1002/dvdy.24008. Epub 2013 Jul 29.

35.

Chromoplexy: a new category of complex rearrangements in the cancer genome.

Shen MM.

Cancer Cell. 2013 May 13;23(5):567-9. doi: 10.1016/j.ccr.2013.04.025.

36.

Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity.

Wang ZA, Mitrofanova A, Bergren SK, Abate-Shen C, Cardiff RD, Califano A, Shen MM.

Nat Cell Biol. 2013 Mar;15(3):274-83. doi: 10.1038/ncb2697. Epub 2013 Feb 24.

37.

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.

Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, Bouché A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):E3231-40. doi: 10.1073/pnas.1204017109. Epub 2012 Nov 5.

38.

Mash1 expression is induced in neuroendocrine prostate cancer upon the loss of Foxa2.

Gupta A, Yu X, Case T, Paul M, Shen MM, Kaestner KH, Matusik RJ.

Prostate. 2013 May;73(6):582-9. doi: 10.1002/pros.22598. Epub 2012 Oct 11.

39.

The roots of cancer: stem cells and the basis for tumor heterogeneity.

Shibata M, Shen MM.

Bioessays. 2013 Mar;35(3):253-60. doi: 10.1002/bies.201200101. Epub 2012 Oct 2. Review.

40.

B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.

Wang J, Kobayashi T, Floc'h N, Kinkade CW, Aytes A, Dankort D, Lefebvre C, Mitrofanova A, Cardiff RD, McMahon M, Califano A, Shen MM, Abate-Shen C.

Cancer Res. 2012 Sep 15;72(18):4765-76. Epub 2012 Jul 25.

41.

Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.

Floc'h N, Kinkade CW, Kobayashi T, Aytes A, Lefebvre C, Mitrofanova A, Cardiff RD, Califano A, Shen MM, Abate-Shen C.

Cancer Res. 2012 Sep 1;72(17):4483-93. doi: 10.1158/0008-5472.CAN-12-0283. Epub 2012 Jul 19.

42.

Development and characterization of a novel CD19CherryLuciferase (CD19CL) transgenic mouse for the preclinical study of B-cell lymphomas.

Scotto L, Kruithof-de Julio M, Paoluzzi L, Kalac M, Marchi E, Buitrago JB, Amengual J, Shen MM, O'Connor OA.

Clin Cancer Res. 2012 Jul 15;18(14):3803-11. doi: 10.1158/1078-0432.CCR-11-2588. Epub 2012 May 15.

43.

Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression.

Vinall RL, Chen JQ, Hubbard NE, Sulaimon SS, Shen MM, Devere White RW, Borowsky AD.

Dis Model Mech. 2012 Nov;5(6):914-20. doi: 10.1242/dmm.008995. Epub 2012 Apr 12.

44.

Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.

Kruithof-de Julio M, Alvarez MJ, Galli A, Chu J, Price SM, Califano A, Shen MM.

Development. 2011 Sep;138(18):3885-95. doi: 10.1242/dev.065656.

45.

Effectiveness of mammography screening in reducing breast cancer mortality in women aged 39-49 years: a meta-analysis.

Magnus MC, Ping M, Shen MM, Bourgeois J, Magnus JH.

J Womens Health (Larchmt). 2011 Jun;20(6):845-52. doi: 10.1089/jwh.2010.2098. Epub 2011 Mar 17.

PMID:
21413892
46.

Revisiting the concept of cancer stem cells in prostate cancer.

Wang ZA, Shen MM.

Oncogene. 2011 Mar 17;30(11):1261-71. doi: 10.1038/onc.2010.530. Epub 2010 Nov 29. Review.

PMID:
21119602
47.

Molecular genetics of prostate cancer: new prospects for old challenges.

Shen MM, Abate-Shen C.

Genes Dev. 2010 Sep 15;24(18):1967-2000. doi: 10.1101/gad.1965810. Review.

48.

Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.

Chu J, Shen MM.

Dev Biol. 2010 Jun 1;342(1):63-73. doi: 10.1016/j.ydbio.2010.03.009. Epub 2010 Mar 24.

49.

A luminal epithelial stem cell that is a cell of origin for prostate cancer.

Wang X, Kruithof-de Julio M, Economides KD, Walker D, Yu H, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM.

Nature. 2009 Sep 24;461(7263):495-500. doi: 10.1038/nature08361. Epub 2009 Sep 9.

50.

Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway.

Leow CC, Wang BE, Ross J, Chan SM, Zha J, Carano RA, Frantz G, Shen MM, de Sauvage FJ, Gao WQ.

J Biol Chem. 2009 Jul 31;284(31):21057-65. doi: 10.1074/jbc.M109.001776. Epub 2009 Jun 3. Erratum in: J Biol Chem. 2011 Dec 16;286(50):43587.

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