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Fractional Deletion of Compound Kushen Injection Indicates Cytokine Signaling Pathways are Critical for its Perturbation of the Cell Cycle.

Aung TN, Nourmohammadi S, Qu Z, Harata-Lee Y, Cui J, Shen HY, Yool AJ, Pukala T, Du H, Kortschak RD, Wei W, Adelson DL.

Sci Rep. 2019 Oct 2;9(1):14200. doi: 10.1038/s41598-019-50271-4.


Analysis of 72 patients with colorectal high-grade neuroendocrine neoplasms from three Chinese hospitals.

Wang ZJ, An K, Li R, Shen W, Bao MD, Tao JH, Chen JN, Mei SW, Shen HY, Ma YB, Zhao FQ, Wei FZ, Liu Q.

World J Gastroenterol. 2019 Sep 14;25(34):5197-5209. doi: 10.3748/wjg.v25.i34.5197.


Intraoperative intraperitoneal chemotherapy increases the incidence of anastomotic leakage after anterior resection of rectal tumors.

Wang ZJ, Tao JH, Chen JN, Mei SW, Shen HY, Zhao FQ, Liu Q.

World J Gastrointest Oncol. 2019 Jul 15;11(7):538-550. doi: 10.4251/wjgo.v11.i7.538.


Microfluidic Chip for Multiplex Detection of Trace Chemical Contaminants Based on Magnetic Encoded Aptamer Probes and Multibranched DNA Nanostructures as Signal Tags.

Chen X, Wang J, Shen HY, Su X, Cao Y, Li T, Gan N.

ACS Sens. 2019 Aug 23;4(8):2131-2139. doi: 10.1021/acssensors.9b00963. Epub 2019 Aug 14.


Cerebrospinal fluid light and heavy neurofilament level increased in anti-N-methyl-d-aspartate receptor encephalitis.

Li J, Gu Y, An H, Zhou Z, Zheng D, Wang Z, Wen Z, Shen HY, Wang Q, Wang H.

Brain Behav. 2019 Aug;9(8):e01354. doi: 10.1002/brb3.1354. Epub 2019 Jul 17.


Higher CSF Levels of NLRP3 Inflammasome Is Associated With Poor Prognosis of Anti-N-methyl-D-Aspartate Receptor Encephalitis.

Peng Y, Liu B, Pei S, Zheng D, Wang Z, Ji T, Pan S, Shen HY, Wang H.

Front Immunol. 2019 May 31;10:905. doi: 10.3389/fimmu.2019.00905. eCollection 2019.


Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).

Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H.

J Autoimmun. 2019 Aug;102:77-88. doi: 10.1016/j.jaut.2019.04.020. Epub 2019 Apr 26.


Long non-coding RNA: The functional regulator of mesenchymal stem cells.

Xie ZY, Wang P, Wu YF, Shen HY.

World J Stem Cells. 2019 Mar 26;11(3):167-179. doi: 10.4252/wjsc.v11.i3.167. Review.


Cell-Free Mitochondrial DNA in the CSF: A Potential Prognostic Biomarker of Anti-NMDAR Encephalitis.

Peng Y, Zheng D, Zhang X, Pan S, Ji T, Zhang J, Shen HY, Wang HH.

Front Immunol. 2019 Feb 6;10:103. doi: 10.3389/fimmu.2019.00103. eCollection 2019.


Adenosine Actions on Oligodendroglia and Myelination in Autism Spectrum Disorder.

Shen HY, Huang N, Reemmer J, Xiao L.

Front Cell Neurosci. 2018 Dec 7;12:482. doi: 10.3389/fncel.2018.00482. eCollection 2018. Review.


Application of contrast enhanced ultrasound in gallbladder lesion: is it helpful to improve the diagnostic capabilities?

Kong WT, Shen HY, Qiu YD, Han H, Wen BJ, Wu M.

Med Ultrason. 2018 Dec 8;20(4):420-426. doi: 10.11152/mu-1626.


Overexpression of Nemo-like kinase promotes the proliferation and invasion of lung cancer cells and indicates poor prognosis.

Lei L, Wang Y, Zheng YW, Fei LR, Shen HY, Li ZH, Huang WJ, Yu JH, Xu HT.

Curr Cancer Drug Targets. 2018 Nov 19. doi: 10.2174/1568009618666181119150521. [Epub ahead of print]


Elevated Soluble Fas and FasL in Cerebrospinal Fluid and Serum of Patients With Anti-N-methyl-D-aspartate Receptor Encephalitis.

Ding YW, Pan SY, Xie W, Shen HY, Wang HH.

Front Neurol. 2018 Oct 25;9:904. doi: 10.3389/fneur.2018.00904. eCollection 2018.


Elevation of YKL-40 in the CSF of Anti-NMDAR Encephalitis Patients Is Associated With Poor Prognosis.

Chen J, Ding Y, Zheng D, Wang Z, Pan S, Ji T, Shen HY, Wang H.

Front Neurol. 2018 Oct 12;9:727. doi: 10.3389/fneur.2018.00727. eCollection 2018.


Oleanolic Acid Inhibits Liver X Receptor Alpha and Pregnane X Receptor to Attenuate Ligand-Induced Lipogenesis.

Lin YN, Chang HY, Wang CCN, Chu FY, Shen HY, Chen CJ, Lim YP.

J Agric Food Chem. 2018 Oct 24;66(42):10964-10976. doi: 10.1021/acs.jafc.8b03372. Epub 2018 Oct 15.


Developmental role of adenosine kinase for the expression of sex-dependent neuropsychiatric behavior.

Osborne DM, Sandau US, Jones AT, Vander Velden JW, Weingarten AM, Etesami N, Huo Y, Shen HY, Boison D.

Neuropharmacology. 2018 Oct;141:89-97. doi: 10.1016/j.neuropharm.2018.08.025. Epub 2018 Aug 23.


Hypoxia Exacerbates Inflammatory Acute Lung Injury via the Toll-Like Receptor 4 Signaling Pathway.

Wu G, Xu G, Chen DW, Gao WX, Xiong JQ, Shen HY, Gao YQ.

Front Immunol. 2018 Jul 23;9:1667. doi: 10.3389/fimmu.2018.01667. eCollection 2018.


Effects of antiepileptic drugs on lipogenic gene regulation and hyperlipidemia risk in Taiwan: a nationwide population-based cohort study and supporting in vitro studies.

Li YW, Wang CH, Chen CJ, Wang CCN, Lin CL, Cheng WK, Shen HY, Lim YP.

Arch Toxicol. 2018 Sep;92(9):2829-2844. doi: 10.1007/s00204-018-2263-3. Epub 2018 Jul 13.


Antifungal activity of the bioactive substance from Bacillus atrophaeus strain HAB-5 and its toxicity assessment on Danio rerio.

Rajaofera MJN, Jin PF, Fan YM, Sun QQ, Huang WK, Wang WB, Shen HY, Zhang S, Lin CH, Liu WB, Zheng FC, Miao WG.

Pestic Biochem Physiol. 2018 May;147:153-161. doi: 10.1016/j.pestbp.2017.06.006. Epub 2017 Jun 7.


An Attempt at Matching Waking Events Into Dream Reports by Independent Judges.

Wang JX, Shen HY.

Front Psychol. 2018 Apr 6;9:465. doi: 10.3389/fpsyg.2018.00465. eCollection 2018.


Odd-skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and β-catenin.

Wang Y, Lei L, Zheng YW, Zhang L, Li ZH, Shen HY, Jiang GY, Zhang XP, Wang EH, Xu HT.

Cancer Sci. 2018 Jun;109(6):1799-1810. doi: 10.1111/cas.13614. Epub 2018 May 23.


CO Adsorption on Metal-Decorated Phosphorene.

Lei SY, Yu ZY, Shen HY, Sun XL, Wan N, Yu H.

ACS Omega. 2018 Apr 9;3(4):3957-3965. doi: 10.1021/acsomega.8b00133. eCollection 2018 Apr 30.


Urinary Metabolomic Study of Chlorogenic Acid in a Rat Model of Chronic Sleep Deprivation Using Gas Chromatography-Mass Spectrometry.

Ma WN, Zhou MM, Gou XJ, Zhao L, Cen F, Xu Y, Shen HY.

Int J Genomics. 2018 Feb 11;2018:1361402. doi: 10.1155/2018/1361402. eCollection 2018.


Neurotrophin-3 released from implant of tissue-engineered fibroin scaffolds inhibits inflammation, enhances nerve fiber regeneration, and improves motor function in canine spinal cord injury.

Li G, Che MT, Zeng X, Qiu XC, Feng B, Lai BQ, Shen HY, Ling EA, Zeng YS.

J Biomed Mater Res A. 2018 Aug;106(8):2158-2170. doi: 10.1002/jbm.a.36414. Epub 2018 Apr 25.


A novel luminescent ionic trinuclear Cu3I2 cluster cuprous complex supported by a P^N ligand: synthesis, structure characterization, properties and TD-DFT calculations.

Zhu QM, Song L, Chai WX, Shen HY, Wei QH, Qin LS.

Acta Crystallogr C Struct Chem. 2018 Jan 1;74(Pt 1):62-68. doi: 10.1107/S2053229617017314. Epub 2018 Jan 1.


Combination treatment with quercetin and resveratrol attenuates high fat diet-induced obesity and associated inflammation in rats via the AMPKα1/SIRT1 signaling pathway.

Zhao L, Cen F, Tian F, Li MJ, Zhang Q, Shen HY, Shen XC, Zhou MM, Du J.

Exp Ther Med. 2017 Dec;14(6):5942-5948. doi: 10.3892/etm.2017.5331. Epub 2017 Oct 18.


The intestinal absorption properties of flavonoids in Hippophaë rhamnoides extracts by an in situ single-pass intestinal perfusion model.

Xin L, Liu XH, Yang J, Shen HY, Ji G, Shi XF, Xie Y.

J Asian Nat Prod Res. 2019 Jan;21(1):62-75. doi: 10.1080/10286020.2017.1396976. Epub 2017 Nov 10.


Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016).

Zhang HY, Liu LG, Ye CY, Chen CH, Hang SX, Zhu Z, Shen HY, Huang ZY, Chen WY, Xue Y.

Virus Genes. 2018 Feb;54(1):41-47. doi: 10.1007/s11262-017-1518-z. Epub 2017 Nov 8.


Correlation between presence of primary iris- and cilliary body cysts and intraocular pressure.

Xue KC, Hu DD, Zhao L, Li N, Shen HY.

Eur Rev Med Pharmacol Sci. 2017 Sep;21(18):3985-3989.


MiR-577 inhibits papillary thyroid carcinoma cell proliferation, migration and invasion by targeting SphK2.

Xue KC, Hu DD, Zhao L, Li N, Shen HY.

Eur Rev Med Pharmacol Sci. 2017 Oct;21(17):3794-3800.


Detection of hereditary hearing loss gene by DNA microarray.

Han GY, Xu Z, Li QS, Shen HY, Zhang W, Liang J.

Eur Rev Med Pharmacol Sci. 2017 Aug;21(16):3538-3542.


Serum and Brain Metabolomic Variations Reveal Perturbation of Sleep Deprivation on Rats and Ameliorate Effect of Total Ginsenoside Treatment.

Gou XJ, Cen F, Fan ZQ, Xu Y, Shen HY, Zhou MM.

Int J Genomics. 2017;2017:5179271. doi: 10.1155/2017/5179271. Epub 2017 Aug 16.


Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer.

Chao TK, Huang TS, Liao YP, Huang RL, Su PH, Shen HY, Lai HC, Wang YC.

PLoS One. 2017 Jul 28;12(7):e0182166. doi: 10.1371/journal.pone.0182166. eCollection 2017.


Using primate neural stem cells cultured in self-assembling peptide nanofiber scaffolds to repair injured spinal cords in rats.

Ye JC, Qin Y, Wu YF, Wang P, Tang Y, Huang L, Ma MJ, Zeng YS, Shen HY.

Spinal Cord. 2018 Jan;56(1):90. doi: 10.1038/sc.2017.85. Epub 2017 Jul 18.


DEPDC1 promotes cell proliferation and tumor growth via activation of E2F signaling in prostate cancer.

Huang L, Chen K, Cai ZP, Chen FC, Shen HY, Zhao WH, Yang SJ, Chen XB, Tang GX, Lin X.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):707-712. doi: 10.1016/j.bbrc.2017.06.105. Epub 2017 Jun 19.


Intraoperative contrast-enhanced ultrasonography for microcirculatory evaluation in rhesus monkey with spinal cord injury.

Huang L, Chen K, Chen FC, Shen HY, Ye JC, Cai ZP, Lin X.

Oncotarget. 2017 Jun 20;8(25):40756-40764. doi: 10.18632/oncotarget.17252.


Antitumor activity of fucoidan in anaplastic thyroid cancer via apoptosis and anti-angiogenesis.

Shen HY, Li LZ, Xue KC, Hu DD, Gao YJ.

Mol Med Rep. 2017 May;15(5):2620-2624. doi: 10.3892/mmr.2017.6338. Epub 2017 Mar 16.


Study of recombinant human interleukin-12 for treatment of complications after radiotherapy for tumor patients.

Guo N, Wang WQ, Gong XJ, Gao L, Yang LR, Yu WN, Shen HY, Wan LQ, Jia XF, Wang YS, Zhao Y.

World J Clin Oncol. 2017 Apr 10;8(2):158-167. doi: 10.5306/wjco.v8.i2.158.


Predictive role of GSTP1-containing exosomes in chemotherapy-resistant breast cancer.

Yang SJ, Wang DD, Li J, Xu HZ, Shen HY, Chen X, Zhou SY, Zhong SL, Zhao JH, Tang JH.

Gene. 2017 Aug 5;623:5-14. doi: 10.1016/j.gene.2017.04.031. Epub 2017 Apr 21.


Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.

Wang Y, Huang N, Li H, Liu S, Chen X, Yu S, Wu N, Bian XW, Shen HY, Li C, Xiao L.

Oncotarget. 2017 Jun 6;8(23):37511-37524. doi: 10.18632/oncotarget.16400.


A new anthraquinone and a new naphthoquinone from the whole plant of Spermacoce latifolia.

Luo Y, Shen HY, Shen QX, Cao ZH, Zhang M, Long SY, Wang ZB, Tan JW.

J Asian Nat Prod Res. 2017 Sep;19(9):869-876. doi: 10.1080/10286020.2017.1279609. Epub 2017 Mar 30.


The miR-30 family: Versatile players in breast cancer.

Yang SJ, Yang SY, Wang DD, Chen X, Shen HY, Zhang XH, Zhong SL, Tang JH, Zhao JH.

Tumour Biol. 2017 Mar;39(3):1010428317692204. doi: 10.1177/1010428317692204. Review.


A Dy4 single-molecule magnet and its Gd(iii), Tb(iii), Ho(iii), and Er(iii) analogues encapsulated by an 8-hydroxyquinoline Schiff base derivative and β-diketonate coligand.

Gao HL, Zhou XP, Bi YX, Shen HY, Wang WM, Wang NN, Chang YX, Zhang RX, Cui JZ.

Dalton Trans. 2017 Apr 5;46(14):4669-4677. doi: 10.1039/c7dt00118e.


Characterizing the Existence of Fluorescence Quenching Agents Using EEM Fluorescence and UV Spectra: Taking the Interaction of Humic Acid and Fe(Ⅲ) as an Example.

Li WH, Wu G, Yao L, Huang XH, Wang JQ, Shen HY, Xue TZ.

Guang Pu Xue Yu Guang Pu Fen Xi. 2017 Mar;37(3):783-7. Chinese, English.


Comparison of bioactive components and pharmacological activities of ophiopogon japonicas extracts from different geographical origins.

Zhao M, Xu WF, Shen HY, Shen PQ, Zhang J, Wang DD, Xu H, Wang H, Yan TT, Wang L, Hao HP, Wang GJ, Cao LJ.

J Pharm Biomed Anal. 2017 May 10;138:134-141. doi: 10.1016/j.jpba.2017.02.013. Epub 2017 Feb 7.


Polyhedral Oligomeric Silsesquioxane Polymer-Caged Silver Nanoparticle as a Smart Colorimetric Probe for the Detection of Hydrogen Sulfide.

Zhang Y, Shen HY, Hai X, Chen XW, Wang JH.

Anal Chem. 2017 Jan 17;89(2):1346-1352. doi: 10.1021/acs.analchem.6b04407. Epub 2016 Dec 22.


Effectiveness of a BHV-1/BEFV bivalent vaccine against bovine herpesvirus type 1 infection in cattle.

Chung YC, Shen HY, Cheng LT, Liu SS, Chu CY.

Res Vet Sci. 2016 Dec;109:161-165. doi: 10.1016/j.rvsc.2016.10.004. Epub 2016 Oct 13.


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