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Items: 14


Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations.

Pino MF, Kim KA, Shelton KD, Lindner J, Odili S, Li C, Collins HW, Shiota M, Matschinsky FM, Magnuson MA.

J Biol Chem. 2007 May 4;282(18):13906-16. Epub 2007 Mar 12.


Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.

Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA.

Dev Cell. 2006 Oct;11(4):583-9. Epub 2006 Sep 7.


Strategies for the use of site-specific recombinases in genome engineering.

Jones JR, Shelton KD, Magnuson MA.

Methods Mol Med. 2005;103:245-57.


Efficient DNA cassette exchange in mouse embryonic stem cells by staggered positive-negative selection.

Long Q, Shelton KD, Lindner J, Jones JR, Magnuson MA.

Genesis. 2004 Aug;39(4):256-62.


Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.

Shiota C, Larsson O, Shelton KD, Shiota M, Efanov AM, Hoy M, Lindner J, Kooptiwut S, Juntti-Berggren L, Gromada J, Berggren PO, Magnuson MA.

J Biol Chem. 2002 Oct 4;277(40):37176-83. Epub 2002 Jul 30.


Generation and functional confirmation of a conditional null PPARgamma allele in mice.

Jones JR, Shelton KD, Guan Y, Breyer MD, Magnuson MA.

Genesis. 2002 Feb;32(2):134-7. No abstract available.


Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism.

She P, Shiota M, Shelton KD, Chalkley R, Postic C, Magnuson MA.

Mol Cell Biol. 2000 Sep;20(17):6508-17.


Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.

Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA.

J Biol Chem. 1999 Jan 1;274(1):305-15.


Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites.

Postic C, Niswender KD, Decaux JF, Parsa R, Shelton KD, Gouhot B, Pettepher CC, Granner DK, Girard J, Magnuson MA.

Genomics. 1995 Oct 10;29(3):740-50.


BZP, a novel serum-responsive zinc finger protein that inhibits gene transcription.

Franklin AJ, Jetton TL, Shelton KD, Magnuson MA.

Mol Cell Biol. 1994 Oct;14(10):6773-88.


Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells.

Shelton KD, Franklin AJ, Khoor A, Beechem J, Magnuson MA.

Mol Cell Biol. 1992 Oct;12(10):4578-89.


An alternate promoter in the glucokinase gene is active in the pancreatic beta cell.

Magnuson MA, Shelton KD.

J Biol Chem. 1989 Sep 25;264(27):15936-42.

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