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Items: 16


Reduced Anti-Histone Antibodies and Increased Risk of Rheumatoid Arthritis Associated with a Single Nucleotide Polymorphism in PADI4 in North Americans.

Mergaert AM, Bawadekar M, Nguyen TQ, Massarenti L, Holmes CL, Rebernick R, Schrodi SJ, Shelef MA.

Int J Mol Sci. 2019 Jun 25;20(12). pii: E3093. doi: 10.3390/ijms20123093.


Reduced IgG titers against pertussis in rheumatoid arthritis: Evidence for a citrulline-biased immune response and medication effects.

Holmes CL, Peyton CG, Bier AM, Donlon TZ, Osman F, Bartels CM, Shelef MA.

PLoS One. 2019 May 28;14(5):e0217221. doi: 10.1371/journal.pone.0217221. eCollection 2019.


Insight into Neutrophil Extracellular Traps through Systematic Evaluation of Citrullination and Peptidylarginine Deiminases.

Holmes CL, Shim D, Kernien J, Johnson CJ, Nett JE, Shelef MA.

J Immunol Res. 2019 Mar 12;2019:2160192. doi: 10.1155/2019/2160192. eCollection 2019.


New relationships for old autoantibodies in rheumatoid arthritis.

Shelef MA.

Arthritis Rheumatol. 2019 Mar 12. doi: 10.1002/art.40879. [Epub ahead of print]


Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3.

Damgaard D, Bawadekar M, Senolt L, Stensballe A, Shelef MA, Nielsen CH.

PLoS One. 2018 Aug 30;13(8):e0203214. doi: 10.1371/journal.pone.0203214. eCollection 2018.


DNA Area and NETosis Analysis (DANA): a High-Throughput Method to Quantify Neutrophil Extracellular Traps in Fluorescent Microscope Images.

Rebernick R, Fahmy L, Glover C, Bawadekar M, Shim D, Holmes CL, Rademacher N, Potluri H, Bartels CM, Shelef MA.

Biol Proced Online. 2018 Apr 1;20:7. doi: 10.1186/s12575-018-0072-y. eCollection 2018.


Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.

Sun B, Dwivedi N, Bechtel TJ, Paulsen JL, Muth A, Bawadekar M, Li G, Thompson PR, Shelef MA, Schiffer CA, Weerapana E, Ho IC.

Sci Immunol. 2017 Jun 9;2(12). pii: eaal3062. doi: 10.1126/sciimmunol.aal3062.


Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation.

Bawadekar M, Shim D, Johnson CJ, Warner TF, Rebernick R, Damgaard D, Nielsen CH, Pruijn GJM, Nett JE, Shelef MA.

J Autoimmun. 2017 Jun;80:39-47. doi: 10.1016/j.jaut.2017.01.006. Epub 2017 Feb 7.


Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation.

Bawadekar M, Gendron-Fitzpatrick A, Rebernick R, Shim D, Warner TF, Nicholas AP, Lundblad LK, Thompson PR, Shelef MA.

Arthritis Res Ther. 2016 Jul 22;18(1):173. doi: 10.1186/s13075-016-1068-0.


Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species.

Moussavi-Harami SF, Mladinich KM, Sackmann EK, Shelef MA, Starnes TW, Guckenberger DJ, Huttenlocher A, Beebe DJ.

Integr Biol (Camb). 2016 Feb;8(2):243-52. doi: 10.1039/c5ib00225g. Epub 2016 Jan 25.


Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis.

Shelef MA, Bennin DA, Yasmin N, Warner TF, Ludwig T, Beggs HE, Huttenlocher A.

Arthritis Res Ther. 2014 Oct 4;16(5):464. doi: 10.1186/s13075-014-0464-6.


Reply: To PMID 24497204.

Shelef MA, Sokolove J, Robinson WH, Huttenlocher A.

Arthritis Rheumatol. 2014 Sep;66(9):2644-5. doi: 10.1002/art.38722. No abstract available.


Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis.

Shelef MA, Sokolove J, Lahey LJ, Wagner CA, Sackmann EK, Warner TF, Wang Y, Beebe DJ, Robinson WH, Huttenlocher A.

Arthritis Rheumatol. 2014 Jun;66(6):1482-91. doi: 10.1002/art.38393.


Neutrophil migration: moving from zebrafish models to human autoimmunity.

Shelef MA, Tauzin S, Huttenlocher A.

Immunol Rev. 2013 Nov;256(1):269-81. doi: 10.1111/imr.12124. Review.


Citrullination of fibronectin modulates synovial fibroblast behavior.

Shelef MA, Bennin DA, Mosher DF, Huttenlocher A.

Arthritis Res Ther. 2012 Nov 5;14(6):R240. doi: 10.1186/ar4083.


Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays.

Sackmann EK, Berthier E, Young EW, Shelef MA, Wernimont SA, Huttenlocher A, Beebe DJ.

Blood. 2012 Oct 4;120(14):e45-53. doi: 10.1182/blood-2012-03-416453. Epub 2012 Aug 22.

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