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Items: 1 to 50 of 147

1.

Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABABR Trafficking.

Corona C, Pasini S, Liu J, Amar F, Greene LA, Shelanski ML.

J Neurosci. 2018 Jul 4;38(27):6102-6113. doi: 10.1523/JNEUROSCI.3350-17.2018. Epub 2018 Jun 6.

PMID:
29875265
2.

Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of Sesn2.

Liu J, Amar F, Corona C, So RWL, Andrews SJ, Nagy PL, Shelanski ML, Greene LA.

Front Mol Neurosci. 2018 Mar 1;11:62. doi: 10.3389/fnmol.2018.00062. eCollection 2018.

3.

Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity.

Qu X, Yuan FN, Corona C, Pasini S, Pero ME, Gundersen GG, Shelanski ML, Bartolini F.

J Cell Biol. 2017 Oct 2;216(10):3161-3178. doi: 10.1083/jcb.201701045. Epub 2017 Sep 6.

4.

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR.

Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19.

PMID:
28631094
5.

Caspase-2 and tau-a toxic partnership?

Troy CM, Shelanski ML.

Nat Med. 2016 Nov 8;22(11):1207-1208. doi: 10.1038/nm.4227. No abstract available.

PMID:
27824824
6.

Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory.

Pasini S, Corona C, Liu J, Greene LA, Shelanski ML.

Cell Rep. 2015 Apr 14;11(2):183-91.

7.

Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.

Aubry S, Shin W, Crary JF, Lefort R, Qureshi YH, Lefebvre C, Califano A, Shelanski ML.

PLoS One. 2015 Mar 17;10(3):e0120352. doi: 10.1371/journal.pone.0120352. eCollection 2015.

8.

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau.

Santa-Maria I, Alaniz ME, Renwick N, Cela C, Fulga TA, Van Vactor D, Tuschl T, Clark LN, Shelanski ML, McCabe BD, Crary JF.

J Clin Invest. 2015 Feb;125(2):681-6. doi: 10.1172/JCI78421. Epub 2015 Jan 9.

9.

Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.

Padmanabhan J, Brown KR, Padilla A, Shelanski ML.

J Biol Chem. 2015 Feb 27;290(9):5267-79. doi: 10.1074/jbc.M114.575225. Epub 2015 Jan 7.

10.

Primary age-related tauopathy (PART): a common pathology associated with human aging.

Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL 3rd, Wisniewski T, Woltjer RL, Yamada M, Nelson PT.

Acta Neuropathol. 2014 Dec;128(6):755-66. doi: 10.1007/s00401-014-1349-0. Epub 2014 Oct 28.

11.

Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology.

Liu J, Pasini S, Shelanski ML, Greene LA.

Front Cell Neurosci. 2014 Jun 30;8:177. doi: 10.3389/fncel.2014.00177. eCollection 2014.

12.

Generation of iPSC lines from archived non-cryoprotected biobanked dura mater.

Sproul AA, Vensand LB, Dusenberry CR, Jacob S, Vonsattel JP, Paull DJ, Shelanski ML, Crary JF, Noggle SA.

Acta Neuropathol Commun. 2014 Jan 7;2:4. doi: 10.1186/2051-5960-2-4.

13.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N; Alzheimer's Disease Genetics Consortium (ADGC), Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL.

Neurology. 2012 Jul 17;79(3):221-8. doi: 10.1212/WNL.0b013e3182605801. Epub 2012 Jun 20.

14.

Synaptic changes in Alzheimer's disease and its models.

Pozueta J, Lefort R, Shelanski ML.

Neuroscience. 2013 Oct 22;251:51-65. doi: 10.1016/j.neuroscience.2012.05.050. Epub 2012 Jun 9. Review.

PMID:
22687952
15.

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD.

Nat Genet. 2011 May;43(5):436-41. doi: 10.1038/ng.801. Epub 2011 Apr 3.

16.

RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.

Malagelada C, López-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA.

J Neurosci. 2011 Mar 2;31(9):3186-96. doi: 10.1523/JNEUROSCI.4011-10.2011.

17.

Increased neurogenesis in young transgenic mice overexpressing human APP(Sw, Ind).

López-Toledano MA, Shelanski ML.

J Alzheimers Dis. 2007 Nov;12(3):229-40.

PMID:
18057556
18.
19.

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

Davidson TJ, Harel S, Arboleda VA, Prunell GF, Shelanski ML, Greene LA, Troy CM.

J Neurosci. 2004 Nov 10;24(45):10040-6. Erratum in: J Neurosci. 2005 Feb 2;25(5):1311.

20.

Dendrite and dendritic spine alterations in Alzheimer models.

Moolman DL, Vitolo OV, Vonsattel JP, Shelanski ML.

J Neurocytol. 2004 May;33(3):377-87.

PMID:
15475691
21.

Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein.

Rabacchi SA, Friedman WJ, Shelanski ML, Troy CM.

Neurobiol Aging. 2004 Sep;25(8):1057-66.

PMID:
15212831
22.

Neurogenic effect of beta-amyloid peptide in the development of neural stem cells.

López-Toledano MA, Shelanski ML.

J Neurosci. 2004 Jun 9;24(23):5439-44.

23.

Caspase-2 redux.

Troy CM, Shelanski ML.

Cell Death Differ. 2003 Jan;10(1):101-7. Review.

24.

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

Troy CM, Rabacchi SA, Hohl JB, Angelastro JM, Greene LA, Shelanski ML.

J Neurosci. 2001 Jul 15;21(14):5007-16. Erratum in: J Neurosci 2001 Aug 15;21(16):1b.

25.

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA.

J Neurochem. 2001 Apr;77(1):157-64.

26.

Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling.

Angelastro JM, Klimaschewski L, Tang S, Vitolo OV, Weissman TA, Donlin LT, Shelanski ML, Greene LA.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10424-9.

27.

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage.

Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA.

J Neurosci. 2000 May 1;20(9):3104-14.

28.

Caspase-2 mediates neuronal cell death induced by beta-amyloid.

Troy CM, Rabacchi SA, Friedman WJ, Frappier TF, Brown K, Shelanski ML.

J Neurosci. 2000 Feb 15;20(4):1386-92.

29.

Primary care outcomes in patients treated by nurse practitioners or physicians: a randomized trial.

Mundinger MO, Kane RL, Lenz ER, Totten AM, Tsai WY, Cleary PD, Friedewald WT, Siu AL, Shelanski ML.

JAMA. 2000 Jan 5;283(1):59-68.

PMID:
10632281
30.

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

Padmanabhan J, Park DS, Greene LA, Shelanski ML.

J Neurosci. 1999 Oct 15;19(20):8747-56.

31.

Abnormal microtubule packing in processes of SF9 cells expressing the FTDP-17 V337M tau mutation.

Frappier T, Liang NS, Brown K, Leung CL, Lynch T, Liem RK, Shelanski ML.

FEBS Lett. 1999 Jul 23;455(3):262-6.

33.
34.

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents.

Park DS, Morris EJ, Padmanabhan J, Shelanski ML, Geller HM, Greene LA.

J Cell Biol. 1998 Oct 19;143(2):457-67.

35.

Process formation in astrocytes: modulation of cytoskeletal proteins.

Padmanabhan J, Shelanski ML.

Neurochem Res. 1998 Mar;23(3):377-84.

PMID:
9482250
36.

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress.

Park DS, Morris EJ, Stefanis L, Troy CM, Shelanski ML, Geller HM, Greene LA.

J Neurosci. 1998 Feb 1;18(3):830-40.

38.

Mechanisms of neuronal degeneration: a final common pathway?

Troy CM, Stefanis L, Greene LA, Shelanski ML.

Adv Neurol. 1997;72:103-11. Review. No abstract available.

PMID:
8993689
39.

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis.

Stefanis L, Park DS, Yan CY, Farinelli SE, Troy CM, Shelanski ML, Greene LA.

J Biol Chem. 1996 Nov 29;271(48):30663-71.

40.
41.

Peripherin: a novel marker for the immunohistochemical study of malformations of the enteric nervous system.

Szabolcs MJ, Visser J, Shelanski ML, O'Toole K, Schullinger JN.

Pediatr Pathol Lab Med. 1996 Jan-Feb;16(1):51-70.

PMID:
8963631
42.

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway.

Troy CM, Derossi D, Prochiantz A, Greene LA, Shelanski ML.

J Neurosci. 1996 Jan;16(1):253-61.

43.

tau Regulation of microtubule-microtubule spacing and bundling.

Frappier TF, Georgieff IS, Brown K, Shelanski ML.

J Neurochem. 1994 Dec;63(6):2288-94.

PMID:
7964749
44.

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells.

Troy CM, Shelanski ML.

Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6384-7.

45.

Cytoskeletons of central and peripheral neurons.

Shelanski ML, Frappier T, Georgieff I, Troy C, Mellado W.

J Neurol Sci. 1994 Jul;124 Suppl:33-7. Review.

PMID:
7807139
46.
47.

Expression of high molecular weight tau in the central and peripheral nervous systems.

Georgieff IS, Liem RK, Couchie D, Mavilia C, Nunez J, Shelanski ML.

J Cell Sci. 1993 Jul;105 ( Pt 3):729-37.

48.

Neurite outgrowth in peripherin-depleted PC12 cells.

Troy CM, Greene LA, Shelanski ML.

J Cell Biol. 1992 Jun;117(5):1085-92.

49.

Primary structure of high molecular weight tau present in the peripheral nervous system.

Couchie D, Mavilia C, Georgieff IS, Liem RK, Shelanski ML, Nunez J.

Proc Natl Acad Sci U S A. 1992 May 15;89(10):4378-81.

50.

Astrocyte process growth induction by actin breakdown.

Baorto DM, Mellado W, Shelanski ML.

J Cell Biol. 1992 Apr;117(2):357-67.

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