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Items: 6


Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion.

Pradhan A, Avelar GM, Bain JM, Childers D, Pelletier C, Larcombe DE, Shekhova E, Netea MG, Brown GD, Erwig L, Gow NAR, Brown AJP.

Nat Commun. 2019 Nov 22;10(1):5315. doi: 10.1038/s41467-019-13298-9.


Redox Proteomic Analysis Reveals Oxidative Modifications of Proteins by Increased Levels of Intracellular Reactive Oxygen Species during Hypoxia Adaptation of Aspergillus fumigatus.

Shekhova E, Ivanova L, Krüger T, Stroe MC, Macheleidt J, Kniemeyer O, Brakhage AA.

Proteomics. 2019 Mar;19(5):e1800339. doi: 10.1002/pmic.201800339. Epub 2019 Feb 13.


Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling.

Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, Gow NAR, Brown AJP.

MBio. 2018 Nov 6;9(6). pii: e01318-18. doi: 10.1128/mBio.01318-18.


Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus.

Shekhova E, Kniemeyer O, Brakhage AA.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00978-17. doi: 10.1128/AAC.00978-17. Print 2017 Nov.


The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus.

Kroll K, Shekhova E, Mattern DJ, Thywissen A, Jacobsen ID, Strassburger M, Heinekamp T, Shelest E, Brakhage AA, Kniemeyer O.

Mol Microbiol. 2016 Jul;101(1):92-108. doi: 10.1111/mmi.13377. Epub 2016 May 3.


Insights into the cellular responses to hypoxia in filamentous fungi.

Hillmann F, Shekhova E, Kniemeyer O.

Curr Genet. 2015 Aug;61(3):441-55. doi: 10.1007/s00294-015-0487-9. Epub 2015 Apr 25. Review.


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