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Items: 27


Effects of Klotho supplementation on hyperoxia-induced renal injury in a rodent model of postnatal nephrogenesis.

Ali MF, Venkatarayappa SKB, Benny M, Rojas C, Yousefi K, Shehadeh LA, Kulandavelu S, Sharma M, Da Silva N, Freundlich M, Abitbol CL, DeFreitas MJ, Young KC.

Pediatr Res. 2020 Feb 14. doi: 10.1038/s41390-020-0803-z. [Epub ahead of print]


Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats.

Benny M, Hernandez DR, Sharma M, Yousefi K, Kulandavelu S, Batlahally S, Zambrano R, Chen P, Martinez EC, Schmidt AF, Shehadeh LA, Vasquez-Padron RI, Wu S, Velazquez OC, Young KC.

Physiol Rep. 2020 Jan;8(1):e14334. doi: 10.14814/phy2.14334.


A preclinical model for phenogroup 3 HFpEF.

Yousefi K, Dunkley JC, Shehadeh LA.

Aging (Albany NY). 2019 Jul 15;11(13):4305-4307. doi: 10.18632/aging.102102. No abstract available.


Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway.

Yousefi K, Irion CI, Takeuchi LM, Ding W, Lambert G, Eisenberg T, Sukkar S, Granzier HL, Methawasin M, Lee DI, Hahn VS, Kass DA, Hatzistergos KE, Hare JM, Webster KA, Shehadeh LA.

J Am Coll Cardiol. 2019 Jun 4;73(21):2705-2718. doi: 10.1016/j.jacc.2019.02.074.


Deletion of Osteopontin Enhances β₂-Adrenergic Receptor-Dependent Anti-Fibrotic Signaling in Cardiomyocytes.

Pollard CM, Desimine VL, Wertz SL, Perez A, Parker BM, Maning J, McCrink KA, Shehadeh LA, Lymperopoulos A.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1396. doi: 10.3390/ijms20061396.


Osteopontin Expression in Cardiomyocytes Is Increased in Pediatric Patients With Sepsis or Pneumonia.

Irion CI, Parrish K, John-Williams K, Gultekin SH, Shehadeh LA.

Front Physiol. 2018 Dec 10;9:1779. doi: 10.3389/fphys.2018.01779. eCollection 2018.


LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring.

Ritter P, Yousefi K, Ramirez J, Dykxhoorn DM, Mendez AJ, Shehadeh LA.

J Vis Exp. 2018 Nov 17;(141). doi: 10.3791/58564.


Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits.

Ding W, Yousefi K, Goncalves S, Goldstein BJ, Sabater AL, Kloosterboer A, Ritter P, Lambert G, Mendez AJ, Shehadeh LA.

JCI Insight. 2018 Mar 22;3(6). pii: 94818. doi: 10.1172/jci.insight.94818.


Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium.

Kurtenbach S, Ding W, Goss GM, Hare JM, Goldstein BJ, Shehadeh LA.

PLoS One. 2017 Nov 6;12(11):e0187576. doi: 10.1371/journal.pone.0187576. eCollection 2017.


New incriminating evidence against IGF2.

Ding W, Shehadeh LA.

Transl Cancer Res. 2017 Aug;6(Suppl 6):S949-S952. doi: 10.21037/tcr.2017.06.07. No abstract available.


Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure.

Li J, Yousefi K, Ding W, Singh J, Shehadeh LA.

Cardiovasc Res. 2017 May 1;113(6):633-643. doi: 10.1093/cvr/cvx016.


Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.

Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, Li J, Shehadeh LA, Hare JM, David V, Martin A, Fornoni A, Di Marco GS, Kentrup D, Reuter S, Mayer AB, Pavenstädt H, Stypmann J, Kuhn C, Hille S, Frey N, Leifheit-Nestler M, Richter B, Haffner D, Abraham R, Bange J, Sperl B, Ullrich A, Brand M, Wolf M, Faul C.

Cell Metab. 2015 Dec 1;22(6):1020-32. doi: 10.1016/j.cmet.2015.09.002. Epub 2015 Oct 1.


miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice.

Ding W, Li J, Singh J, Alif R, Vazquez-Padron RI, Gomes SA, Hare JM, Shehadeh LA.

Cardiovasc Res. 2015 Apr 1;106(1):131-42. doi: 10.1093/cvr/cvv030. Epub 2015 Feb 12. Erratum in: Cardiovasc Res. 2016 Mar 1;109(3):373.


Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells.

Hu X, Wu R, Shehadeh LA, Zhou Q, Jiang C, Huang X, Zhang L, Gao F, Liu X, Yu H, Webster KA, Wang J.

BMC Genomics. 2014 Apr 23;15:303. doi: 10.1186/1471-2164-15-303.


Ribonucleic acid biomarkers for heart failure is there a correlation between heart and blood transcriptomics?

Shehadeh LA, Hare JM.

JACC Heart Fail. 2013 Dec;1(6):477-9. No abstract available.


Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling.

Rodriguez-Menocal L, Faridi MH, Martinez L, Shehadeh LA, Duque JC, Wei Y, Mesa A, Pena A, Gupta V, Pham SM, Vazquez-Padron RI.

Am J Physiol Heart Circ Physiol. 2014 Mar 1;306(5):H641-53. doi: 10.1152/ajpheart.00641.2013. Epub 2014 Jan 10.


MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300.

Shehadeh LA, Sharma S, Pessanha M, Wei JQ, Liu J, Yuan H, Rodrigues CO, Scherr M, Tsinoremas NF, Bishopric NH.

PLoS One. 2013 Nov 13;8(11):e79133. doi: 10.1371/journal.pone.0079133. eCollection 2013.


MicroRNAs: a new piece in the paediatric cardiovascular disease puzzle.

Omran A, Elimam D, Webster KA, Shehadeh LA, Yin F.

Cardiol Young. 2013 Oct;23(5):642-55. doi: 10.1017/S1047951113000048. Epub 2013 Feb 26. Review.


Dynamic regulation of vascular myosin light chain (MYL9) with injury and aging.

Shehadeh LA, Webster KA, Hare JM, Vazquez-Padron RI.

PLoS One. 2011;6(10):e25855. doi: 10.1371/journal.pone.0025855. Epub 2011 Oct 7.


Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells.

Rodrigues CO, Shehadeh LA, Hoosien M, Otero V, Chopra I, Tsinoremas NF, Bishopric NH.

PLoS One. 2011;6(8):e24013. doi: 10.1371/journal.pone.0024013. Epub 2011 Aug 24.


Expression of the Argonaute protein PiwiL2 and piRNAs in adult mouse mesenchymal stem cells.

Wu Q, Ma Q, Shehadeh LA, Wilson A, Xia L, Yu H, Webster KA.

Biochem Biophys Res Commun. 2010 Jun 11;396(4):915-20. doi: 10.1016/j.bbrc.2010.05.022. Epub 2010 May 10.


Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells.

Wilson A, Shehadeh LA, Yu H, Webster KA.

BMC Genomics. 2010 Apr 7;11:229. doi: 10.1186/1471-2164-11-229.


SRRM2, a potential blood biomarker revealing high alternative splicing in Parkinson's disease.

Shehadeh LA, Yu K, Wang L, Guevara A, Singer C, Vance J, Papapetropoulos S.

PLoS One. 2010 Feb 8;5(2):e9104. doi: 10.1371/journal.pone.0009104.


Extracellular matrix-induced gene expression in human breast cancer cells.

Garamszegi N, Garamszegi SP, Shehadeh LA, Scully SP.

Mol Cancer Res. 2009 Mar;7(3):319-29. doi: 10.1158/1541-7786.MCR-08-0227. Epub 2009 Mar 10.


Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.

Wei JQ, Shehadeh LA, Mitrani JM, Pessanha M, Slepak TI, Webster KA, Bishopric NH.

Circulation. 2008 Aug 26;118(9):934-46. doi: 10.1161/CIRCULATIONAHA.107.760488. Epub 2008 Aug 12.


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