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Items: 1 to 50 of 117

1.

A single KH domain in Bicaudal-C links mRNA binding and translational repression functions to maternal development.

Dowdle ME, Park S, Blaser Imboden S, Fox CA, Houston DW, Sheets MD.

Development. 2019 May 15;146(10). pii: dev172486. doi: 10.1242/dev.172486.

PMID:
31023875
2.

Assaying NanoLuc Luciferase Activity from mRNA-Injected Xenopus Embryos.

Sheets MD.

Methods Mol Biol. 2019;1920:33-39. doi: 10.1007/978-1-4939-9009-2_3.

PMID:
30737684
3.

Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation.

Slosarek EL, Schuh AL, Pustova I, Johnson A, Bird J, Johnson M, Frankel EB, Bhattacharya N, Hanna MG, Burke JE, Ruhl DA, Quinney K, Block S, Peotter JL, Chapman ER, Sheets MD, Butcher SE, Stagg SM, Audhya A.

Cell Rep. 2018 Aug 28;24(9):2248-2260. doi: 10.1016/j.celrep.2018.07.081.

4.

Precision Targeted Therapy with BLU-667 for RET-Driven Cancers.

Subbiah V, Gainor JF, Rahal R, Brubaker JD, Kim JL, Maynard M, Hu W, Cao Q, Sheets MP, Wilson D, Wilson KJ, DiPietro L, Fleming P, Palmer M, Hu MI, Wirth L, Brose MS, Ou SI, Taylor M, Garralda E, Miller S, Wolf B, Lengauer C, Guzi T, Evans EK.

Cancer Discov. 2018 Jul;8(7):836-849. doi: 10.1158/2159-8290.CD-18-0338. Epub 2018 Apr 15.

5.

Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway.

Fink DM, Sun MR, Heyne GW, Everson JL, Chung HM, Park S, Sheets MD, Lipinski RJ.

Cell Signal. 2018 Apr;44:1-9. doi: 10.1016/j.cellsig.2017.12.007. Epub 2017 Dec 26.

6.

Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes.

Dowdle ME, Imboden SB, Park S, Ryder SP, Sheets MD.

J Vis Exp. 2017 Jul 28;(125). doi: 10.3791/56031.

7.

Controlling the Messenger: Regulated Translation of Maternal mRNAs in Xenopus laevis Development.

Sheets MD, Fox CA, Dowdle ME, Blaser SI, Chung A, Park S.

Adv Exp Med Biol. 2017;953:49-82. Review.

8.

A gradient of maternal Bicaudal-C controls vertebrate embryogenesis via translational repression of mRNAs encoding cell fate regulators.

Park S, Blaser S, Marchal MA, Houston DW, Sheets MD.

Development. 2016 Mar 1;143(5):864-71. doi: 10.1242/dev.131359. Epub 2016 Jan 25.

9.

Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels.

Sheets MF, Fozzard HA, Hanck DA.

Biophys J. 2015 Dec 1;109(11):2277-86. doi: 10.1016/j.bpj.2015.10.012.

10.

Building the Future: Post-transcriptional Regulation of Cell Fate Decisions Prior to the Xenopus Midblastula Transition.

Sheets MD.

Curr Top Dev Biol. 2015;113:233-70. doi: 10.1016/bs.ctdb.2015.06.008. Epub 2015 Aug 13. Review.

PMID:
26358875
11.

First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.

Hagel M, Miduturu C, Sheets M, Rubin N, Weng W, Stransky N, Bifulco N, Kim JL, Hodous B, Brooijmans N, Shutes A, Winter C, Lengauer C, Kohl NE, Guzi T.

Cancer Discov. 2015 Apr;5(4):424-37. doi: 10.1158/2159-8290.CD-14-1029. Epub 2015 Mar 16.

12.

In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing.

Tjin Tham Sjin R, Lee K, Walter AO, Dubrovskiy A, Sheets M, Martin TS, Labenski MT, Zhu Z, Tester R, Karp R, Medikonda A, Chaturvedi P, Ren Y, Haringsma H, Etter J, Raponi M, Simmons AD, Harding TC, Niu D, Nacht M, Westlin WF, Petter RC, Allen A, Singh J.

Mol Cancer Ther. 2014 Jun;13(6):1468-79. doi: 10.1158/1535-7163.MCT-13-0966. Epub 2014 Apr 10.

13.

Determinants of RNA binding and translational repression by the Bicaudal-C regulatory protein.

Zhang Y, Park S, Blaser S, Sheets MD.

J Biol Chem. 2014 Mar 14;289(11):7497-504. doi: 10.1074/jbc.M113.526426. Epub 2014 Jan 29.

14.

Women's responses to changes in U.S. Preventive Task Force's mammography screening guidelines: results of focus groups with ethnically diverse women.

Allen JD, Bluethmann SM, Sheets M, Opdyke KM, Gates-Ferris K, Hurlbert M, Harden E.

BMC Public Health. 2013 Dec 12;13:1169. doi: 10.1186/1471-2458-13-1169.

15.

Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC.

Walter AO, Sjin RT, Haringsma HJ, Ohashi K, Sun J, Lee K, Dubrovskiy A, Labenski M, Zhu Z, Wang Z, Sheets M, St Martin T, Karp R, van Kalken D, Chaturvedi P, Niu D, Nacht M, Petter RC, Westlin W, Lin K, Jaw-Tsai S, Raponi M, Van Dyke T, Etter J, Weaver Z, Pao W, Singh J, Simmons AD, Harding TC, Allen A.

Cancer Discov. 2013 Dec;3(12):1404-15. doi: 10.1158/2159-8290.CD-13-0314. Epub 2013 Sep 24.

16.

Bicaudal-C spatially controls translation of vertebrate maternal mRNAs.

Zhang Y, Cooke A, Park S, Dewey CN, Wickens M, Sheets MD.

RNA. 2013 Nov;19(11):1575-82. doi: 10.1261/rna.041665.113. Epub 2013 Sep 23.

17.

Outward stabilization of the voltage sensor in domain II but not domain I speeds inactivation of voltage-gated sodium channels.

Sheets MF, Chen T, Hanck DA.

Am J Physiol Heart Circ Physiol. 2013 Oct 15;305(8):H1213-21. doi: 10.1152/ajpheart.00225.2013. Epub 2013 Jul 26.

18.

Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans.

Evans EK, Tester R, Aslanian S, Karp R, Sheets M, Labenski MT, Witowski SR, Lounsbury H, Chaturvedi P, Mazdiyasni H, Zhu Z, Nacht M, Freed MI, Petter RC, Dubrovskiy A, Singh J, Westlin WF.

J Pharmacol Exp Ther. 2013 Aug;346(2):219-28. doi: 10.1124/jpet.113.203489. Epub 2013 May 24.

PMID:
23709115
19.

Health beliefs, attitudes and service utilization among Haitians.

Allen JD, Mars DR, Tom L, Apollon G, Hilaire D, Iralien G, Cloutier LB, Sheets MM, Zamor R.

J Health Care Poor Underserved. 2013 Feb;24(1):106-19. doi: 10.1353/hpu.2013.0015.

PMID:
23377722
20.

Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kα.

Nacht M, Qiao L, Sheets MP, St Martin T, Labenski M, Mazdiyasni H, Karp R, Zhu Z, Chaturvedi P, Bhavsar D, Niu D, Westlin W, Petter RC, Medikonda AP, Singh J.

J Med Chem. 2013 Feb 14;56(3):712-21. doi: 10.1021/jm3008745. Epub 2013 Feb 5.

PMID:
23360348
21.

CNLs make a difference!

Sheets M, Bonnah B, Kareivis J, Abraham P, Sweeney M, Strauss J.

Nursing. 2012 Aug;42(8):54-8. doi: 10.1097/01.NURSE.0000415837.20995.e2. No abstract available.

PMID:
22832631
22.

Transcriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer.

Reid CD, Zhang Y, Sheets MD, Kessler DS.

Dev Biol. 2012 Aug 15;368(2):231-41. doi: 10.1016/j.ydbio.2012.05.018. Epub 2012 May 22.

23.

Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation.

Friend K, Brook M, Bezirci FB, Sheets MD, Gray NK, Seli E.

Biochem J. 2012 Jul 1;445(1):93-100. doi: 10.1042/BJ20120304.

24.

Ethics: Put education ahead of new limitations.

Sheets M.

Am J Orthod Dentofacial Orthop. 2012 Mar;141(3):256-7. doi: 10.1016/j.ajodo.2012.01.007. No abstract available.

PMID:
22381480
25.

The sodium channel as a target for local anesthetic drugs.

Fozzard HA, Sheets MF, Hanck DA.

Front Pharmacol. 2011 Nov 1;2:68. doi: 10.3389/fphar.2011.00068. eCollection 2011.

26.

Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis.

Lund E, Sheets MD, Imboden SB, Dahlberg JE.

Genes Dev. 2011 Jun 1;25(11):1121-31. doi: 10.1101/gad.2038811. Epub 2011 May 16.

27.

Superacid-promoted additions involving vinyl-substituted pyrimidines, quinoxalines, and quinazolines: mechanisms correlated to charge distributions.

Zhang Y, Sheets MR, Raja EK, Boblak KN, Klumpp DA.

J Am Chem Soc. 2011 Jun 8;133(22):8467-9. doi: 10.1021/ja202557z. Epub 2011 May 12.

28.

Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development.

Gorgoni B, Richardson WA, Burgess HM, Anderson RC, Wilkie GS, Gautier P, Martins JP, Brook M, Sheets MD, Gray NK.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7844-9. doi: 10.1073/pnas.1017664108. Epub 2011 Apr 25.

29.

Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine.

Hagel M, Niu D, St Martin T, Sheets MP, Qiao L, Bernard H, Karp RM, Zhu Z, Labenski MT, Chaturvedi P, Nacht M, Westlin WF, Petter RC, Singh J.

Nat Chem Biol. 2011 Jan;7(1):22-4. doi: 10.1038/nchembio.492. Epub 2010 Nov 28.

PMID:
21113170
30.

Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel.

Sheets MF, Chen T, Hanck DA.

Pflugers Arch. 2011 Jan;461(1):91-7. doi: 10.1007/s00424-010-0894-1. Epub 2010 Oct 28.

31.

The tetrodotoxin receptor of voltage-gated sodium channels--perspectives from interactions with micro-conotoxins.

French RJ, Yoshikami D, Sheets MF, Olivera BM.

Mar Drugs. 2010 Jul 13;8(7):2153-61. doi: 10.3390/md8072153. Review.

32.

Sodium channel molecular conformations and antiarrhythmic drug affinity.

Sheets MF, Fozzard HA, Lipkind GM, Hanck DA.

Trends Cardiovasc Med. 2010 Jan;20(1):16-21. doi: 10.1016/j.tcm.2010.03.002. Review.

33.

Polyribosome analysis for investigating mRNA translation in Xenopus oocytes, eggs and embryos.

Sheets MD, Fritz B, Hartley RS, Zhang Y.

Methods. 2010 May;51(1):152-6. doi: 10.1016/j.ymeth.2010.01.023. Epub 2010 Jan 22.

34.

Nonanticoagulant heparin reduces myocyte Na+ and Ca2+ loading during simulated ischemia and decreases reperfusion injury.

Barry WH, Zhang XQ, Halkos ME, Vinten-Johansen J, Saegusa N, Spitzer KW, Matsuoka N, Sheets M, Rao NV, Kennedy TP.

Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H102-11. doi: 10.1152/ajpheart.00316.2009. Epub 2009 Oct 23.

35.

Deadenylation of maternal mRNAs mediated by miR-427 in Xenopus laevis embryos.

Lund E, Liu M, Hartley RS, Sheets MD, Dahlberg JE.

RNA. 2009 Dec;15(12):2351-63. doi: 10.1261/rna.1882009. Epub 2009 Oct 23.

36.

Alternate pathway of infection with Hepatozoon americanum and the epidemiologic importance of predation.

Johnson EM, Panciera RJ, Allen KE, Sheets ME, Beal JD, Ewing SA, Little SE.

J Vet Intern Med. 2009 Nov-Dec;23(6):1315-8. doi: 10.1111/j.1939-1676.2009.0375.x. Epub 2009 Aug 26.

37.

Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity.

Hanck DA, Nikitina E, McNulty MM, Fozzard HA, Lipkind GM, Sheets MF.

Circ Res. 2009 Aug 28;105(5):492-9. doi: 10.1161/CIRCRESAHA.109.198572. Epub 2009 Aug 6.

38.

Toward defining the phosphoproteome of Xenopus laevis embryos.

McGivern JV, Swaney DL, Coon JJ, Sheets MD.

Dev Dyn. 2009 Jun;238(6):1433-43. doi: 10.1002/dvdy.21941.

39.

Spatially restricted translation of the xCR1 mRNA in Xenopus embryos.

Zhang Y, Forinash KD, McGivern J, Fritz B, Dorey K, Sheets MD.

Mol Cell Biol. 2009 Jul;29(13):3791-802. doi: 10.1128/MCB.01865-08. Epub 2009 Apr 13.

40.

Superelectrophilic chemistry of imidazoles.

Sheets MR, Li A, Bower EA, Weigel AR, Abbott MP, Gallo RM, Mitton AA, Klumpp DA.

J Org Chem. 2009 Mar 20;74(6):2502-7. doi: 10.1021/jo802798x.

PMID:
19215114
42.

Structural basis for RNA recognition by a type II poly(A)-binding protein.

Song J, McGivern JV, Nichols KW, Markley JL, Sheets MD.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15317-22. doi: 10.1073/pnas.0801274105. Epub 2008 Sep 29.

43.

Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.

Sheets MF, Hanck DA.

J Physiol. 2007 Jul 1;582(Pt 1):317-34. Epub 2007 May 17.

44.

Predictors of aggression on the psychiatric inpatient service: self-esteem, narcissism, and theory of mind deficits.

Goldberg BR, Serper MR, Sheets M, Beech D, Dill C, Duffy KG.

J Nerv Ment Dis. 2007 May;195(5):436-42.

PMID:
17502810
45.

Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.

Chen YW, Smith ML, Sheets M, Ballaron S, Trevillyan JM, Burke SE, Rosenberg T, Henry C, Wagner R, Bauch J, Marsh K, Fey TA, Hsieh G, Gauvin D, Mollison KW, Carter GW, Djuric SW.

J Cardiovasc Pharmacol. 2007 Apr;49(4):228-35.

PMID:
17438408
46.

Chordin affects pronephros development in Xenopus embryos by anteriorizing presomitic mesoderm.

Mitchell T, Jones EA, Weeks DL, Sheets MD.

Dev Dyn. 2007 Jan;236(1):251-61.

47.

Site-3 toxins and cardiac sodium channels.

Hanck DA, Sheets MF.

Toxicon. 2007 Feb;49(2):181-93. Epub 2006 Sep 27. Review.

48.
49.

Heading in a new direction: implications of the revised fate map for understanding Xenopus laevis development.

Lane MC, Sheets MD.

Dev Biol. 2006 Aug 1;296(1):12-28. Epub 2006 Apr 21. Review.

50.

Reduced voltage dependence of inactivation in the SCN5A sodium channel mutation delF1617.

Chen T, Inoue M, Sheets MF.

Am J Physiol Heart Circ Physiol. 2005 Jun;288(6):H2666-76. Epub 2005 Jan 21.

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