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The Liverpool duodenum-and spleen-preserving near-total pancreatectomy can provide long-term pain relief in patients with end-stage chronic pancreatitis.

Sheel ARG, Baron RD, Dickerson LD, Ghaneh P, Campbell F, Raraty MGT, Yip V, Halloran CM, Neoptolemos JP.

Langenbecks Arch Surg. 2019 Nov 20. doi: 10.1007/s00423-019-01837-3. [Epub ahead of print]


Perfusion of Intrapulmonary Arteriovenous Anastomoses Is Not Related to VO2max in Hypoxia and Is Unchanged by Oral Sildenafil.

Carter EA, Koch S, O'Donovan JP, Sheel AW, Milsom WK, Koehle MS.

High Alt Med Biol. 2019 Oct 16. doi: 10.1089/ham.2019.0051. [Epub ahead of print]


Analysis of maximal expiratory flow-volume curves in adult survivors of preterm birth.

Molgat-Seon Y, Dominelli PB, Peters CM, Guenette JA, Sheel AW, Gladstone IM, Lovering AT, Duke JW.

Am J Physiol Regul Integr Comp Physiol. 2019 Oct 1;317(4):R588-R596. doi: 10.1152/ajpregu.00114.2019. Epub 2019 Aug 21.


Pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis: New insights on an old topic.

Olesen SS, Krarup H, Poulsen JL, Christensen JH, Sheel ARG, Sutton R, Greenhalf W, Halloran C, Drewes AM.

United European Gastroenterol J. 2019 Aug;7(7):955-964. doi: 10.1177/2050640619846011. Epub 2019 Apr 16.


Modelling the effects of age and sex on the resistive and viscoelastic components of the work of breathing during exercise.

Molgat-Seon Y, Dominelli PB, Guenette JA, Sheel AW.

Exp Physiol. 2019 Nov;104(11):1737-1745. doi: 10.1113/EP087956. Epub 2019 Aug 27.


Diaphragm fatigue and inspiratory muscle metaboreflex in men and women matched for absolute diaphragmatic work during pressure-threshold loading.

Geary CM, Welch JF, McDonald MR, Peters CM, Leahy MG, Reinhard PA, Sheel AW.

J Physiol. 2019 Sep;597(18):4797-4808. doi: 10.1113/JP278380. Epub 2019 Aug 18.


Breathing during exercise: There is no such thing as a free lunch.

Sheel AW, Dominelli PB.

Exp Physiol. 2019 Sep;104(9):1333-1334. doi: 10.1113/EP087922. Epub 2019 Jul 30. No abstract available.


Real-time imaging of integrin β4 dynamics using a reporter cell line generated by Crispr/Cas9 genome editing.

Elaimy AL, Wang M, Sheel A, Brown CW, Walker MR, Amante JJ, Xue W, Chan A, Baer CE, Goel HL, Mercurio AM.

J Cell Sci. 2019 Jul 31;132(15). pii: jcs231241. doi: 10.1242/jcs.231241.


Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes.

Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W.

Hepatology. 2019 Jun 12. doi: 10.1002/hep.30807. [Epub ahead of print]


Respiratory muscle training in athletes with cervical spinal cord injury: effects on cardiopulmonary function and exercise capacity.

Gee CM, Williams AM, Sheel AW, Eves ND, West CR.

J Physiol. 2019 Jul;597(14):3673-3685. doi: 10.1113/JP277943. Epub 2019 Jun 11.


CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling.

Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W.

Genome Med. 2019 Apr 16;11(1):21. doi: 10.1186/s13073-019-0627-9.


Qualitative dimensions of exertional dyspnea in fibrotic interstitial lung disease.

Schaeffer MR, Guenette JA, Ramsook AH, Molgat-Seon Y, Mitchell RA, Wilkie SS, Dhillon SS, Sheel AW, Ryerson CJ.

Respir Physiol Neurobiol. 2019 Aug;266:1-8. doi: 10.1016/j.resp.2019.04.004. Epub 2019 Apr 12.


Sex Differences in the Pulmonary System Influence the Integrative Response to Exercise.

Dominelli PB, Molgat-Seon Y, Sheel AW.

Exerc Sport Sci Rev. 2019 Jul;47(3):142-150. doi: 10.1249/JES.0000000000000188.


Sildenafil does not improve performance in 16.1 km cycle exercise time-trial in acute hypoxia.

Carter EA, Sheel AW, Milsom WK, Koehle MS.

PLoS One. 2019 Jan 17;14(1):e0210841. doi: 10.1371/journal.pone.0210841. eCollection 2019.


The Mechanics of Breathing during Swimming.

Leahy MG, Summers MN, Peters CM, Molgat-Seon Y, Geary CM, Sheel AW.

Med Sci Sports Exerc. 2019 Jul;51(7):1467-1476. doi: 10.1249/MSS.0000000000001902.


Manipulation of mechanical ventilatory constraint during moderate intensity exercise does not influence dyspnoea in healthy older men and women.

Molgat-Seon Y, Ramsook AH, Peters CM, Schaeffer MR, Dominelli PB, Romer LM, Road JD, Guenette JA, Sheel AW.

J Physiol. 2019 Mar;597(5):1383-1399. doi: 10.1113/JP277476. Epub 2019 Jan 18.


Effect of increased inspiratory muscle work on blood flow to inactive and active limbs during submaximal dynamic exercise.

Katayama K, Goto K, Shimizu K, Saito M, Ishida K, Zhang L, Shiozawa K, Sheel AW.

Exp Physiol. 2019 Feb;104(2):180-188. doi: 10.1113/EP087380. Epub 2018 Dec 9.


Exercise-induced arterial hypoxemia; some answers, more questions.

Dominelli PB, Sheel AW.

Appl Physiol Nutr Metab. 2019 Jun;44(6):571-579. doi: 10.1139/apnm-2018-0468. Epub 2018 Nov 9. Review.


Work of breathing influences muscle sympathetic nerve activity during semi-recumbent cycle exercise.

Dominelli PB, Katayama K, Vermeulen TD, Stuckless TJR, Brown CV, Foster GE, Sheel AW.

Acta Physiol (Oxf). 2019 Apr;225(4):e13212. doi: 10.1111/apha.13212. Epub 2018 Nov 25.


Identification of Cystic Lesions by Secondary Screening of Familial Pancreatic Cancer (FPC) Kindreds Is Not Associated with the Stratified Risk of Cancer.

Sheel ARG, Harrison S, Sarantitis I, Nicholson JA, Hanna T, Grocock C, Raraty M, Ramesh J, Farooq A, Costello E, Jackson R, Chapman M, Smith A, Carter R, Mckay C, Hamady Z, Aithal GP, Mountford R, Ghaneh P, Hammel P, Lerch MM, Halloran C, Pereira SP, Greenhalf W.

Am J Gastroenterol. 2019 Jan;114(1):155-164. doi: 10.1038/s41395-018-0395-y.


Effect of diaphragm fatigue on subsequent exercise tolerance in healthy men and women.

Welch JF, Archiza B, Guenette JA, West CR, Sheel AW.

J Appl Physiol (1985). 2018 Dec 1;125(6):1987-1996. doi: 10.1152/japplphysiol.00630.2018. Epub 2018 Oct 11.


Guidelines for the Diagnostic Cross Sectional Imaging and Severity Scoring of Chronic Pancreatitis.

Frøkjær JB, Akisik F, Farooq A, Akpinar B, Dasyam A, Drewes AM, Haldorsen IS, Morana G, Neoptolemos JP, Olesen SS, Petrone MC, Sheel A, Shimosoegawa T, Whitcomb DC; Working group for the International (IAP – APA – JPS – EPC) Consensus Guidelines for Chronic Pancreatitis.

Pancreatology. 2018 Oct;18(7):764-773. doi: 10.1016/j.pan.2018.08.012. Epub 2018 Aug 28.


The diagnostic value of Rosemont and Japanese diagnostic criteria for 'indeterminate', 'suggestive', 'possible' and 'early' chronic pancreatitis.

Sheel ARG, Baron RD, Sarantitis I, Ramesh J, Ghaneh P, Raraty MGT, Yip V, Sutton R, Goulden MR, Campbell F, Farooq A, Healey P, Jackson R, Halloran CM, Neoptolemos JP.

Pancreatology. 2018 Oct;18(7):774-784. doi: 10.1016/j.pan.2018.08.002. Epub 2018 Aug 7.


Does competitive swimming affect lung growth?

Bovard JM, Welch JF, Houghton KM, McKenzie DC, Potts JE, Sheel AW.

Physiol Rep. 2018 Aug;6(15):e13816. doi: 10.14814/phy2.13816.


Competition for blood flow distribution between respiratory and locomotor muscles: implications for muscle fatigue.

Sheel AW, Boushel R, Dempsey JA.

J Appl Physiol (1985). 2018 Sep 1;125(3):820-831. doi: 10.1152/japplphysiol.00189.2018. Epub 2018 Jun 7. Review.


International consensus statements on early chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with The International Association of Pancreatology, American Pancreatic Association, Japan Pancreas Society, PancreasFest Working Group and European Pancreatic Club.

Whitcomb DC, Shimosegawa T, Chari ST, Forsmark CE, Frulloni L, Garg P, Hegyi P, Hirooka Y, Irisawa A, Ishikawa T, Isaji S, Lerch MM, Levy P, Masamune A, Wilcox CM, Windsor J, Yadav D, Sheel A, Neoptolemos JP; Working Group for the International (IAP – APA – JPS – EPC) Consensus Guidelines for Chronic Pancreatitis.

Pancreatology. 2018 May 21. pii: S1424-3903(18)30113-3. doi: 10.1016/j.pan.2018.05.008. [Epub ahead of print]


Cardiopulmonary Demand of 16-kg Kettlebell Snatches in Simulated Girevoy Sport.

Chan M, MacInnis MJ, Koch S, MacLeod KE, Lohse KR, Gallo ME, Sheel AW, Koehle MS.

J Strength Cond Res. 2018 May 17. doi: 10.1519/JSC.0000000000002588. [Epub ahead of print]


Sex differences in diaphragmatic fatigue: the cardiovascular response to inspiratory resistance.

Welch JF, Archiza B, Guenette JA, West CR, Sheel AW.

J Physiol. 2018 Sep;596(17):4017-4032. doi: 10.1113/JP275794. Epub 2018 Jun 12.


Group-based physical activity for older adults (GOAL) randomized controlled trial: Exercise adherence outcomes.

Beauchamp MR, Ruissen GR, Dunlop WL, Estabrooks PA, Harden SM, Wolf SA, Liu Y, Schmader T, Puterman E, Sheel AW, Rhodes RE.

Health Psychol. 2018 May;37(5):451-461. doi: 10.1037/hea0000615.


Effects of Age and Sex on Inspiratory Muscle Activation Patterns during Exercise.

Molgat-Seon Y, Dominelli PB, Ramsook AH, Schaeffer MR, Romer LM, Road JD, Guenette JA, Sheel AW.

Med Sci Sports Exerc. 2018 Sep;50(9):1882-1891. doi: 10.1249/MSS.0000000000001648.


Myocardial Infarction Injury in Patients with Chronic Lung Disease Entering Pulmonary Rehabilitation: Frequency and Association with Heart Rate Parameters.

Sima CA, Lau BC, Taylor CM, van Eeden SF, Reid WD, Sheel AW, Kirkham AR, Camp PG.

PM R. 2018 Sep;10(9):917-925. doi: 10.1016/j.pmrj.2018.03.005. Epub 2018 Mar 14.


The effects of age and sex on mechanical ventilatory constraint and dyspnea during exercise in healthy humans.

Molgat-Seon Y, Dominelli PB, Ramsook AH, Schaeffer MR, Molgat Sereacki S, Foster GE, Romer LM, Road JD, Guenette JA, Sheel AW.

J Appl Physiol (1985). 2018 Apr 1;124(4):1092-1106. doi: 10.1152/japplphysiol.00608.2017. Epub 2017 Dec 14.


Temporal characteristics of exercise-induced diaphragmatic fatigue.

Archiza B, Welch JF, Geary CM, Allen GP, Borghi-Silva A, Sheel AW.

J Appl Physiol (1985). 2018 Apr 1;124(4):906-914. doi: 10.1152/japplphysiol.00942.2017. Epub 2017 Dec 28.


Neurophysiological mechanisms of exertional dyspnoea in fibrotic interstitial lung disease.

Schaeffer MR, Ryerson CJ, Ramsook AH, Molgat-Seon Y, Wilkie SS, Dhillon SS, Mitchell RA, Sheel AW, Khalil N, Camp PG, Guenette JA.

Eur Respir J. 2018 Jan 18;51(1). pii: 1701726. doi: 10.1183/13993003.01726-2017. Print 2018 Jan.


Oral contraceptives modulate the muscle metaboreflex in healthy young women.

Parmar HR, Sears J, Molgat-Seon Y, McCulloch CL, McCracken LA, Brown CV, Sheel AW, Dominelli PB.

Appl Physiol Nutr Metab. 2018 May;43(5):460-466. doi: 10.1139/apnm-2017-0482. Epub 2017 Dec 5.


Premature birth affects the degree of airway dysanapsis and mechanical ventilatory constraints.

Duke JW, Gladstone IM, Sheel AW, Lovering AT.

Exp Physiol. 2018 Feb 1;103(2):261-275. doi: 10.1113/EP086588. Epub 2017 Dec 20.


Treatment and prognostic factors of patients with thymic epithelial tumors at first recurrence or progression.

Banna GL, Sheel A, Sheel V, Bille A, Routledge T, Fernando S, Nair A, Lal R.

Future Oncol. 2017 Nov;13(27):2429-2439. doi: 10.2217/fon-2017-0236. Epub 2017 Nov 10.


Recovery of gold from electronic waste using chemical assisted microbial biosorption (hybrid) technique.

Sheel A, Pant D.

Bioresour Technol. 2018 Jan;247:1189-1192. doi: 10.1016/j.biortech.2017.08.212. Epub 2017 Sep 2.


Effects of respiratory muscle work on respiratory and locomotor blood flow during exercise.

Dominelli PB, Archiza B, Ramsook AH, Mitchell RA, Peters CM, Molgat-Seon Y, Henderson WR, Koehle MS, Boushel R, Sheel AW.

Exp Physiol. 2017 Nov 1;102(11):1535-1547. doi: 10.1113/EP086566. Epub 2017 Sep 24.


Classical experiments in whole-body metabolism: closed-circuit respirometry.

Archiza B, Welch JF, Sheel AW.

Eur J Appl Physiol. 2017 Oct;117(10):1929-1937. doi: 10.1007/s00421-017-3681-2. Epub 2017 Jul 26. Review.


Guidelines for the understanding and management of pain in chronic pancreatitis.

Drewes AM, Bouwense SAW, Campbell CM, Ceyhan GO, Delhaye M, Demir IE, Garg PK, van Goor H, Halloran C, Isaji S, Neoptolemos JP, Olesen SS, Palermo T, Pasricha PJ, Sheel A, Shimosegawa T, Szigethy E, Whitcomb DC, Yadav D; Working group for the International (IAP – APA – JPS – EPC) Consensus Guidelines for Chronic Pancreatitis.

Pancreatology. 2017 Sep - Oct;17(5):720-731. doi: 10.1016/j.pan.2017.07.006. Epub 2017 Jul 13. Review.


The reliability of short-term measurement of heart rate variability during spontaneous breathing in people with chronic obstructive pulmonary disease.

Sima CA, Inskip JA, Sheel AW, van Eeden SF, Reid WD, Camp PG.

Rev Port Pneumol (2006). 2017 Nov - Dec;23(6):338-342. doi: 10.1016/j.rppnen.2017.06.001. Epub 2017 Jul 8.


Influence of inspiratory resistive loading on expiratory muscle fatigue in healthy humans.

Peters CM, Welch JF, Dominelli PB, Molgat-Seon Y, Romer LM, McKenzie DC, Sheel AW.

Exp Physiol. 2017 Sep 1;102(9):1221-1233. doi: 10.1113/EP086346. Epub 2017 Jul 22.


CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.

Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W.

Genome Biol. 2017 Jun 14;18(1):108. doi: 10.1186/s13059-017-1237-8.


Reliability of the diaphragmatic compound muscle action potential evoked by cervical magnetic stimulation and recorded via chest wall surface EMG.

Welch JF, Mildren RL, Zaback M, Archiza B, Allen GP, Sheel AW.

Respir Physiol Neurobiol. 2017 Sep;243:101-106. doi: 10.1016/j.resp.2017.05.011. Epub 2017 May 29.


Effects of hyperoxia on dyspnoea and exercise endurance in fibrotic interstitial lung disease.

Schaeffer MR, Ryerson CJ, Ramsook AH, Molgat-Seon Y, Wilkie SS, Dhillon SS, Mitchell RA, Sheel AW, Khalil N, Camp PG, Guenette JA.

Eur Respir J. 2017 May 25;49(5). pii: 1602494. doi: 10.1183/13993003.02494-2016. Print 2017 May. No abstract available.


Exercise-induced quadriceps muscle fatigue in men and women: effects of arterial oxygen content and respiratory muscle work.

Dominelli PB, Molgat-Seon Y, Griesdale DEG, Peters CM, Blouin JS, Sekhon M, Dominelli GS, Henderson WR, Foster GE, Romer LM, Koehle MS, Sheel AW.

J Physiol. 2017 Aug 1;595(15):5227-5244. doi: 10.1113/JP274068. Epub 2017 Jun 19.


Lung volume recruitment acutely increases respiratory system compliance in individuals with severe respiratory muscle weakness.

Molgat-Seon Y, Hannan LM, Dominelli PB, Peters CM, Fougere RJ, McKim DA, Sheel AW, Road JD.

ERJ Open Res. 2017 Mar 14;3(1). pii: 00135-2016. doi: 10.1183/23120541.00135-2016. eCollection 2017 Jan.


Cerebral blood flow, frontal lobe oxygenation and intra-arterial blood pressure during sprint exercise in normoxia and severe acute hypoxia in humans.

Curtelin D, Morales-Alamo D, Torres-Peralta R, Rasmussen P, Martin-Rincon M, Perez-Valera M, Siebenmann C, Pérez-Suárez I, Cherouveim E, Sheel AW, Lundby C, Calbet JA.

J Cereb Blood Flow Metab. 2018 Jan;38(1):136-150. doi: 10.1177/0271678X17691986. Epub 2017 Feb 10.


Functional respiratory imaging, regional strain, and expiratory time constants at three levels of positive end expiratory pressure in an ex vivo pig model.

Henderson WR, Molgat-Seon Y, Vos W, Lipson R, Ferreira F, Kirby M, Holsbeke CV, Dominelli PB, Griesdale DE, Sekhon M, Coxson HO, Mayo J, Sheel AW.

Physiol Rep. 2016 Dec;4(23). pii: e13059.

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