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Items: 28


A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.

Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK.

Nat Biotechnol. 2018 Oct;36(9):865-874. doi: 10.1038/nbt.4226. Epub 2018 Aug 20.


Traction force microscopy of engineered cardiac tissues.

Pasqualini FS, Agarwal A, O'Connor BB, Liu Q, Sheehy SP, Parker KK.

PLoS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706. eCollection 2018.


Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model.

Chantre CO, Campbell PH, Golecki HM, Buganza AT, Capulli AK, Deravi LF, Dauth S, Sheehy SP, Paten JA, Gledhill K, Doucet YS, Abaci HE, Ahn S, Pope BD, Ruberti JW, Hoerstrup SP, Christiano AM, Parker KK.

Biomaterials. 2018 Jun;166:96-108. doi: 10.1016/j.biomaterials.2018.03.006. Epub 2018 Mar 5.


Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications.

Nawroth JC, Scudder LL, Halvorson RT, Tresback J, Ferrier JP, Sheehy SP, Cho A, Kannan S, Sunyovszki I, Goss JA, Campbell PH, Parker KK.

Biofabrication. 2018 Jan 16;10(2):025004. doi: 10.1088/1758-5090/aa96de.


JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement.

Capulli AK, Emmert MY, Pasqualini FS, Kehl D, Caliskan E, Lind JU, Sheehy SP, Park SJ, Ahn S, Weber B, Goss JA, Hoerstrup SP, Parker KK.

Biomaterials. 2017 Jul;133:229-241. doi: 10.1016/j.biomaterials.2017.04.033. Epub 2017 Apr 18.


Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes.

Sheehy SP, Grosberg A, Qin P, Behm DJ, Ferrier JP, Eagleson MA, Nesmith AP, Krull D, Falls JG, Campbell PH, McCain ML, Willette RN, Hu E, Parker KK.

Exp Biol Med (Maywood). 2017 Nov;242(17):1643-1656. doi: 10.1177/1535370217701006. Epub 2017 Mar 26.


Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction - From cardioprotection to functional repair in a translational pig infarction model.

Emmert MY, Wolint P, Jakab A, Sheehy SP, Pasqualini FS, Nguyen TDL, Hilbe M, Seifert B, Weber B, Brokopp CE, Macejovska D, Caliskan E, von Eckardstein A, Schwartlander R, Vogel V, Falk V, Parker KK, Gyöngyösi M, Hoerstrup SP.

Biomaterials. 2017 Apr;122:48-62. doi: 10.1016/j.biomaterials.2016.11.029. Epub 2016 Nov 23.


Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.

Pasqualini FS, Nesmith AP, Horton RE, Sheehy SP, Parker KK.

Biomed Res Int. 2016;2016:4081638. doi: 10.1155/2016/4081638. Epub 2016 Dec 4. Review.


Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip.

Dauth S, Maoz BM, Sheehy SP, Hemphill MA, Murty T, Macedonia MK, Greer AM, Budnik B, Parker KK.

J Neurophysiol. 2017 Mar 1;117(3):1320-1341. doi: 10.1152/jn.00575.2016. Epub 2016 Dec 28.


Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy.

Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KK.

J Cell Biol. 2016 Feb 15;212(4):389-97. doi: 10.1083/jcb.201508026. Epub 2016 Feb 8.


Angiotensin II Induced Cardiac Dysfunction on a Chip.

Horton RE, Yadid M, McCain ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK.

PLoS One. 2016 Jan 25;11(1):e0146415. doi: 10.1371/journal.pone.0146415. eCollection 2016.


Fibrous scaffolds for building hearts and heart parts.

Capulli AK, MacQueen LA, Sheehy SP, Parker KK.

Adv Drug Deliv Rev. 2016 Jan 15;96:83-102. doi: 10.1016/j.addr.2015.11.020. Epub 2015 Dec 4. Review.


Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes.

Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK.

Exp Biol Med (Maywood). 2015 Nov;240(11):1543-54. doi: 10.1177/1535370215583799. Epub 2015 Apr 23.


Structural phenotyping of stem cell-derived cardiomyocytes.

Pasqualini FS, Sheehy SP, Agarwal A, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2015 Mar 10;4(3):340-7. doi: 10.1016/j.stemcr.2015.01.020. Epub 2015 Feb 26.


Quality metrics for stem cell-derived cardiac myocytes.

Sheehy SP, Pasqualini F, Grosberg A, Park SJ, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2014 Mar 6;2(3):282-94. doi: 10.1016/j.stemcr.2014.01.015. eCollection 2014 Mar 11.


The structure-function relationships of a natural nanoscale photonic device in cuttlefish chromatophores.

Deravi LF, Magyar AP, Sheehy SP, Bell GR, Mäthger LM, Senft SL, Wardill TJ, Lane WS, Kuzirian AM, Hanlon RT, Hu EL, Parker KK.

J R Soc Interface. 2014 Jan 29;11(93):20130942. doi: 10.1098/rsif.2013.0942. Print 2014 Apr 6.


Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes.

Feinberg AW, Ripplinger CM, van der Meer P, Sheehy SP, Domian I, Chien KR, Parker KK.

Stem Cell Reports. 2013 Nov 7;1(5):387-96. doi: 10.1016/j.stemcr.2013.10.004. eCollection 2013.


Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip.

McCain ML, Sheehy SP, Grosberg A, Goss JA, Parker KK.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9770-5. doi: 10.1073/pnas.1304913110. Epub 2013 May 28.


Myocyte shape regulates lateral registry of sarcomeres and contractility.

Kuo PL, Lee H, Bray MA, Geisse NA, Huang YT, Adams WJ, Sheehy SP, Parker KK.

Am J Pathol. 2012 Dec;181(6):2030-7. doi: 10.1016/j.ajpath.2012.08.045.


The contribution of cellular mechanotransduction to cardiomyocyte form and function.

Sheehy SP, Grosberg A, Parker KK.

Biomech Model Mechanobiol. 2012 Nov;11(8):1227-39. doi: 10.1007/s10237-012-0419-2. Epub 2012 Jul 7.


Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture.

Feinberg AW, Alford PW, Jin H, Ripplinger CM, Werdich AA, Sheehy SP, Grosberg A, Parker KK.

Biomaterials. 2012 Aug;33(23):5732-41. doi: 10.1016/j.biomaterials.2012.04.043. Epub 2012 May 15.


Self-organization of muscle cell structure and function.

Grosberg A, Kuo PL, Guo CL, Geisse NA, Bray MA, Adams WJ, Sheehy SP, Parker KK.

PLoS Comput Biol. 2011 Feb;7(2):e1001088. doi: 10.1371/journal.pcbi.1001088. Epub 2011 Feb 24.


Hierarchical architecture influences calcium dynamics in engineered cardiac muscle.

Pong T, Adams WJ, Bray MA, Feinberg AW, Sheehy SP, Werdich AA, Parker KK.

Exp Biol Med (Maywood). 2011 Mar;236(3):366-73. doi: 10.1258/ebm.2010.010239. Epub 2011 Feb 17.


Nuclear morphology and deformation in engineered cardiac myocytes and tissues.

Bray MA, Adams WJ, Geisse NA, Feinberg AW, Sheehy SP, Parker KK.

Biomaterials. 2010 Jul;31(19):5143-50. doi: 10.1016/j.biomaterials.2010.03.028. Epub 2010 Apr 10.


Biohybrid thin films for measuring contractility in engineered cardiovascular muscle.

Alford PW, Feinberg AW, Sheehy SP, Parker KK.

Biomaterials. 2010 May;31(13):3613-21. doi: 10.1016/j.biomaterials.2010.01.079. Epub 2010 Feb 9.


Time-warped comparison of gene expression in adaptive and maladaptive cardiac hypertrophy.

Sheehy SP, Huang S, Parker KK.

Circ Cardiovasc Genet. 2009 Apr;2(2):116-24. doi: 10.1161/CIRCGENETICS.108.806935. Epub 2009 Feb 18.


Control of myocyte remodeling in vitro with engineered substrates.

Geisse NA, Sheehy SP, Parker KK.

In Vitro Cell Dev Biol Anim. 2009 Jul-Aug;45(7):343-50. doi: 10.1007/s11626-009-9182-9. Epub 2009 Feb 28.


Sarcomere alignment is regulated by myocyte shape.

Bray MA, Sheehy SP, Parker KK.

Cell Motil Cytoskeleton. 2008 Aug;65(8):641-51. doi: 10.1002/cm.20290.

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