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Items: 1 to 50 of 125

1.

Effect of an Energy-Restricted, Nutritionally Complete, Higher Protein Meal Plan on Body Composition and Mobility in Older Adults With Obesity: A Randomized Controlled Trial.

Beavers KM, Nesbit BA, Kiel JR, Sheedy JL, Arterburn LM, Collins AE, Ford SA, Henderson RM, Coleman CD, Beavers DP.

J Gerontol A Biol Sci Med Sci. 2018 Jun 21. doi: 10.1093/gerona/gly146. [Epub ahead of print]

PMID:
30629126
2.

The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.

Friesen WJ, Johnson B, Sierra J, Zhuo J, Vazirani P, Xue X, Tomizawa Y, Baiazitov R, Morrill C, Ren H, Babu S, Moon YC, Branstrom A, Mollin A, Hedrick J, Sheedy J, Elfring G, Weetall M, Colacino JM, Welch EM, Peltz SW.

PLoS One. 2018 Oct 25;13(10):e0206158. doi: 10.1371/journal.pone.0206158. eCollection 2018.

3.

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties.

Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W, Du J, Sheedy J, Hedrick J, Risher N, Yeh S, Qi H, Arasu T, Hwang S, Lennox W, Kong R, Petruska J, Moon YC, Babiak J, Davis TW, Jacobson A, Almstead NG, Branstrom A, Colacino JM, Peltz SW.

Mol Cancer Ther. 2019 Jan;18(1):3-16. doi: 10.1158/1535-7163.MCT-18-0863. Epub 2018 Oct 23.

PMID:
30352802
4.

Correction to Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria.

Gerasyuto AI, Arnold MA, Wang J, Chen G, Zhang X, Smith S, Woll MG, Baird J, Zhang N, Almstead NG, Narasimhan J, Peddi S, Dumble M, Sheedy J, Weetall M, Branstrom AA, Prasad JVN, Karp GM.

J Med Chem. 2018 Oct 25;61(20):9394. doi: 10.1021/acs.jmedchem.8b01538. Epub 2018 Oct 16. No abstract available.

5.

BMI1 is a therapeutic target in recurrent medulloblastoma.

Bakhshinyan D, Venugopal C, Adile AA, Garg N, Manoranjan B, Hallett R, Wang X, Mahendram S, Vora P, Vijayakumar T, Subapanditha M, Singh M, Kameda-Smith MM, Qazi M, McFarlane N, Mann A, Ajani OA, Yarascavitch B, Ramaswamy V, Farooq H, Morrissy S, Cao L, Sydorenko N, Baiazitov R, Du W, Sheedy J, Weetall M, Moon YC, Lee CS, Kwiecien JM, Delaney KH, Doble B, Cho YJ, Mitra S, Kaplan D, Taylor MD, Davis TW, Singh SK.

Oncogene. 2018 Oct 22. doi: 10.1038/s41388-018-0549-9. [Epub ahead of print]

PMID:
30348991
6.

Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria.

Gerasyuto AI, Arnold MA, Wang J, Chen G, Zhang X, Smith S, Woll MG, Baird J, Zhang N, Almstead NG, Narasimhan J, Peddi S, Dumble M, Sheedy J, Weetall M, Branstrom AA, Prasad JVN, Karp GM.

J Med Chem. 2018 May 24;61(10):4456-4475. doi: 10.1021/acs.jmedchem.8b00114. Epub 2018 May 14. Erratum in: J Med Chem. 2018 Oct 25;61(20):9394.

7.

Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells.

Harvey AJ, O'Brien C, Lambshead J, Sheedy JR, Rathjen J, Laslett AL, Gardner DK.

PLoS One. 2018 Mar 15;13(3):e0193949. doi: 10.1371/journal.pone.0193949. eCollection 2018.

8.

Effect of Exercise Type During Intentional Weight Loss on Body Composition in Older Adults with Obesity.

Beavers KM, Ambrosius WT, Rejeski WJ, Burdette JH, Walkup MP, Sheedy JL, Nesbit BA, Gaukstern JE, Nicklas BJ, Marsh AP.

Obesity (Silver Spring). 2017 Nov;25(11):1823-1829. doi: 10.1002/oby.21977.

9.

4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis.

Arnold MA, Gerasyuto AI, Wang J, Du W, Gorske YJK, Arasu T, Baird J, Almstead NG, Narasimhan J, Peddi S, Ginzburg O, Lue SW, Hedrick J, Sheedy J, Lagaud G, Branstrom AA, Weetall M, Prasad JVNV, Karp GM.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5014-5021. doi: 10.1016/j.bmcl.2017.10.006. Epub 2017 Oct 5.

PMID:
29032026
10.

The nucleoside analog clitocine is a potent and efficacious readthrough agent.

Friesen WJ, Trotta CR, Tomizawa Y, Zhuo J, Johnson B, Sierra J, Roy B, Weetall M, Hedrick J, Sheedy J, Takasugi J, Moon YC, Babu S, Baiazitov R, Leszyk JD, Davis TW, Colacino JM, Peltz SW, Welch EM.

RNA. 2017 Apr;23(4):567-577. doi: 10.1261/rna.060236.116. Epub 2017 Jan 17.

11.

Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform.

Cao L, Weetall M, Bombard J, Qi H, Arasu T, Lennox W, Hedrick J, Sheedy J, Risher N, Brooks PC, Trifillis P, Trotta C, Moon YC, Babiak J, Almstead NG, Colacino JM, Davis TW, Peltz SW.

PLoS One. 2016 Dec 16;11(12):e0168366. doi: 10.1371/journal.pone.0168366. eCollection 2016.

12.

Discovery and Optimization of Small Molecule Splicing Modifiers of Survival Motor Neuron 2 as a Treatment for Spinal Muscular Atrophy.

Woll MG, Qi H, Turpoff A, Zhang N, Zhang X, Chen G, Li C, Huang S, Yang T, Moon YC, Lee CS, Choi S, Almstead NG, Naryshkin NA, Dakka A, Narasimhan J, Gabbeta V, Welch E, Zhao X, Risher N, Sheedy J, Weetall M, Karp GM.

J Med Chem. 2016 Jul 14;59(13):6070-85. doi: 10.1021/acs.jmedchem.6b00460. Epub 2016 Jul 6.

PMID:
27299569
13.

Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy.

Zhao X, Feng Z, Ling KK, Mollin A, Sheedy J, Yeh S, Petruska J, Narasimhan J, Dakka A, Welch EM, Karp G, Chen KS, Metzger F, Ratni H, Lotti F, Tisdale S, Naryshkin NA, Pellizzoni L, Paushkin S, Ko CP, Weetall M.

Hum Mol Genet. 2016 May 15;25(10):1885-1899. Epub 2016 Feb 29.

14.

Computer vision syndrome: A review.

Gowrisankaran S, Sheedy JE.

Work. 2015;52(2):303-14. doi: 10.3233/WOR-152162. Review.

PMID:
26519133
15.

Expert Views on Innovative Future Uses for Contact Lenses.

Jones LW, Chauhan A, Di Girolamo N, Sheedy J, Smith E 3rd.

Optom Vis Sci. 2016 Apr;93(4):328-35. doi: 10.1097/OPX.0000000000000700. Review.

PMID:
26390344
16.

Assessing Walking Activity in Older Adults: Development and Validation of a Novel Computer-Animated Assessment Tool.

Marsh AP, Janssen JA, Ip EH, Barnard RT, Ambrosius WT, Brubaker PR, Burdette JH, Sheedy JL, Rejeski WJ.

J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1555-61. doi: 10.1093/gerona/glv101. Epub 2015 Aug 10.

17.

Distinct profiles of human embryonic stem cell metabolism and mitochondria identified by oxygen.

Lees JG, Rathjen J, Sheedy JR, Gardner DK, Harvey AJ.

Reproduction. 2015 Oct;150(4):367-82. doi: 10.1530/REP-14-0633. Epub 2015 Jul 9.

PMID:
26159831
18.

Fathers that are born small program alterations in the next-generation preimplantation rat embryos.

Master JS, Thouas GA, Harvey AJ, Sheedy JR, Hannan NJ, Gardner DK, Wlodek ME.

J Nutr. 2015 May;145(5):876-83. doi: 10.3945/jn.114.205724. Epub 2015 Mar 25.

PMID:
25809684
19.

Male obesity is associated with changed spermatozoa Cox4i1 mRNA level and altered seminal vesicle fluid composition in a mouse model.

Binder NK, Sheedy JR, Hannan NJ, Gardner DK.

Mol Hum Reprod. 2015 May;21(5):424-34. doi: 10.1093/molehr/gav010. Epub 2015 Mar 2.

PMID:
25731709
20.

Low female birth weight and advanced maternal age programme alterations in next-generation blastocyst development.

Master JS, Thouas GA, Harvey AJ, Sheedy JR, Hannan NJ, Gardner DK, Wlodek ME.

Reproduction. 2015 May;149(5):497-510. doi: 10.1530/REP-14-0619. Epub 2015 Feb 9.

PMID:
25667431
21.

(1)H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium-vitamin-D3 supplementation in older men.

Sheedy JR, Gooley PR, Nahid A, Tull DL, McConville MJ, Kukuljan S, Nowson CA, Daly RM, Ebeling PR.

Appl Physiol Nutr Metab. 2014 Nov;39(11):1294-304. doi: 10.1139/apnm-2014-0060. Epub 2014 Jul 23.

PMID:
25198310
22.

Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.

Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, Furia B, Risher N, Sheedy J, Kong R, Ma J, Turpoff A, Lee CS, Zhang X, Moon YC, Trifillis P, Welch EM, Colacino JM, Babiak J, Almstead NG, Peltz SW, Eng LA, Chen KS, Mull JL, Lynes MS, Rubin LL, Fontoura P, Santarelli L, Haehnke D, McCarthy KD, Schmucki R, Ebeling M, Sivaramakrishnan M, Ko CP, Paushkin SV, Ratni H, Gerlach I, Ghosh A, Metzger F.

Science. 2014 Aug 8;345(6197):688-93. doi: 10.1126/science.1250127.

23.

Effect of font size and glare on computer tasks in young and older adults.

Ko P, Mohapatra A, Bailey IL, Sheedy J, Rempel DM.

Optom Vis Sci. 2014 Jun;91(6):682-9. doi: 10.1097/OPX.0000000000000274.

PMID:
24830373
24.

Structure-activity relationship (SAR) optimization of 6-(indol-2-yl)pyridine-3-sulfonamides: identification of potent, selective, and orally bioavailable small molecules targeting hepatitis C (HCV) NS4B.

Zhang N, Zhang X, Zhu J, Turpoff A, Chen G, Morrill C, Huang S, Lennox W, Kakarla R, Liu R, Li C, Ren H, Almstead N, Venkatraman S, Njoroge FG, Gu Z, Clausen V, Graci J, Jung SP, Zheng Y, Colacino JM, Lahser F, Sheedy J, Mollin A, Weetall M, Nomeir A, Karp GM.

J Med Chem. 2014 Mar 13;57(5):2121-35. doi: 10.1021/jm401621g. Epub 2013 Dec 4.

PMID:
24266880
25.

Impact of oxygen concentration on adult murine pre-antral follicle development in vitro and the corresponding metabolic profile.

Gook DA, Edgar DH, Lewis K, Sheedy JR, Gardner DK.

Mol Hum Reprod. 2014 Jan;20(1):31-41. doi: 10.1093/molehr/gat062. Epub 2013 Sep 6.

PMID:
24013158
26.

The Cooperative Lifestyle Intervention Program-II (CLIP-II): design and methods.

Marsh AP, Janssen JA, Ambrosius WT, Burdette JH, Gaukstern JE, Morgan AR, Nesbit BA, Paolini JB, Sheedy JL, Rejeski WJ.

Contemp Clin Trials. 2013 Nov;36(2):382-93. doi: 10.1016/j.cct.2013.08.006. Epub 2013 Aug 23.

27.

Metabolite analysis of biological fluids and tissues by proton nuclear magnetic resonance spectroscopy.

Sheedy JR.

Methods Mol Biol. 2013;1055:81-97. doi: 10.1007/978-1-62703-577-4_7.

PMID:
23963905
28.

Comparison of three techniques in measuring progressive addition lenses.

Huang CY, Raasch TW, Yi AY, Sheedy JE, Andre B, Bullimore MA.

Optom Vis Sci. 2012 Nov;89(11):1564-73. doi: 10.1097/OPX.0b013e31826ca26b.

PMID:
23069724
29.

Vision and IT displays: a whole new visual world.

Rosenfield M, Howarth PA, Sheedy JE, Crossland MD.

Ophthalmic Physiol Opt. 2012 Sep;32(5):363-6. doi: 10.1111/j.1475-1313.2012.00936.x. No abstract available.

PMID:
22882149
30.

Comparative effect of lens care solutions on blink rate, ocular discomfort and visual performance.

Yang SN, Tai YC, Sheedy JE, Kinoshita B, Lampa M, Kern JR.

Ophthalmic Physiol Opt. 2012 Sep;32(5):412-20. doi: 10.1111/j.1475-1313.2012.00922.x. Epub 2012 Jul 7.

PMID:
22775005
31.

Stereoscopic viewing and reported perceived immersion and symptoms.

Yang SN, Schlieski T, Selmins B, Cooper SC, Doherty RA, Corriveau PJ, Sheedy JE.

Optom Vis Sci. 2012 Jul;89(7):1068-80. doi: 10.1097/OPX.0b013e31825da430.

PMID:
22733100
32.

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome.

Armstrong CW, McGregor NR, Sheedy JR, Buttfield I, Butt HL, Gooley PR.

Clin Chim Acta. 2012 Oct 9;413(19-20):1525-31. doi: 10.1016/j.cca.2012.06.022. Epub 2012 Jun 21.

PMID:
22728138
33.

Asthenopia and blink rate under visual and cognitive loads.

Gowrisankaran S, Nahar NK, Hayes JR, Sheedy JE.

Optom Vis Sci. 2012 Jan;89(1):97-104. doi: 10.1097/OPX.0b013e318236dd88.

PMID:
22051780
34.

Effects of ocular transverse chromatic aberration on peripheral word identification.

Yang SN, Tai YC, Laukkanen H, Sheedy JE.

Vision Res. 2011 Nov;51(21-22):2273-81. doi: 10.1016/j.visres.2011.08.022. Epub 2011 Sep 10.

35.

Interactions of visual and cognitive stress.

Nahar NK, Gowrisankaran S, Hayes JR, Sheedy JE.

Optometry. 2011 Nov;82(11):689-96. doi: 10.1016/j.optm.2011.07.003. Epub 2011 Aug 31.

PMID:
21885351
36.

BMI1 as a novel target for drug discovery in cancer.

Cao L, Bombard J, Cintron K, Sheedy J, Weetall ML, Davis TW.

J Cell Biochem. 2011 Oct;112(10):2729-41. doi: 10.1002/jcb.23234. Review.

PMID:
21678481
37.

Emergency department prediction of post-concussive syndrome following mild traumatic brain injury--an international cross-validation study.

Faux S, Sheedy J, Delaney R, Riopelle R.

Brain Inj. 2011;25(1):14-22. doi: 10.3109/02699052.2010.531686.

PMID:
21142827
38.

Effects of postural and visual stressors on myofascial trigger point development and motor unit rotation during computer work.

Hoyle JA, Marras WS, Sheedy JE, Hart DE.

J Electromyogr Kinesiol. 2011 Feb;21(1):41-8. doi: 10.1016/j.jelekin.2010.04.006. Epub 2010 Jun 26.

PMID:
20580571
39.

A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine.

Sheedy JR, Ebeling PR, Gooley PR, McConville MJ.

Anal Biochem. 2010 Mar 15;398(2):263-5. doi: 10.1016/j.ab.2009.11.027. Epub 2009 Nov 23.

PMID:
19941831
40.

Emergency department assessment of mild traumatic brain injury and the prediction of postconcussive symptoms: a 3-month prospective study.

Sheedy J, Harvey E, Faux S, Geffen G, Shores EA.

J Head Trauma Rehabil. 2009 Sep-Oct;24(5):333-43. doi: 10.1097/HTR.0b013e3181aea51f.

PMID:
19858967
41.

Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.

Sheshgiri R, Gustafsson F, Sheedy J, Rao V, Ross HJ, Delgado DH.

J Heart Lung Transplant. 2009 Nov;28(11):1193-7. doi: 10.1016/j.healun.2009.07.009. Epub 2009 Sep 26.

PMID:
19783164
42.

Effects of ocular transverse chromatic aberration on near foveal letter recognition.

Yang SN, Tai YC, Laukkanen H, Sheedy J.

Vision Res. 2009 Nov;49(23):2881-90. doi: 10.1016/j.visres.2009.09.005. Epub 2009 Sep 15.

43.

Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome.

Sheedy JR, Wettenhall RE, Scanlon D, Gooley PR, Lewis DP, McGregor N, Stapleton DI, Butt HL, DE Meirleir KL.

In Vivo. 2009 Jul-Aug;23(4):621-8.

44.

The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients.

Gustafsson F, Barth D, Delgado DH, Nsouli M, Sheedy J, Ross HJ.

Eur J Clin Pharmacol. 2009 Jul;65(7):659-65. doi: 10.1007/s00228-009-0663-2. Epub 2009 May 21.

PMID:
19458944
45.

A prospective controlled study in the prevalence of posttraumatic headache following mild traumatic brain injury.

Faux S, Sheedy J.

Pain Med. 2008 Nov;9(8):1001-11. doi: 10.1111/j.1526-4637.2007.00404.x. Epub 2008 Feb 5.

PMID:
18266807
46.

The diagnostic accuracy of the Revised Westmead PTA Scale as an adjunct to the Glasgow Coma Scale in the early identification of cognitive impairment in patients with mild traumatic brain injury.

Shores EA, Lammél A, Hullick C, Sheedy J, Flynn M, Levick W, Batchelor J.

J Neurol Neurosurg Psychiatry. 2008 Oct;79(10):1100-6. doi: 10.1136/jnnp.2007.132571. Epub 2008 Jan 25.

PMID:
18223020
47.

The effects of visual display distance on eye accommodation, head posture, and vision and neck symptoms.

Rempel D, Willms K, Anshel J, Jaschinski W, Sheedy J.

Hum Factors. 2007 Oct;49(5):830-8.

PMID:
17915601
48.

Computer use, symptoms, and quality of life.

Hayes JR, Sheedy JE, Stelmack JA, Heaney CA.

Optom Vis Sci. 2007 Aug;84(8):738-44.

PMID:
17700327
49.

Objective measurements of lower-level visual stress.

Nahar NK, Sheedy JE, Hayes J, Tai YC.

Optom Vis Sci. 2007 Jul;84(7):620-9.

PMID:
17632311
50.

Eyelid squint response to asthenopia-inducing conditions.

Gowrisankaran S, Sheedy JE, Hayes JR.

Optom Vis Sci. 2007 Jul;84(7):611-9.

PMID:
17632310

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