Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30

1.

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Shearer JD, Saylor ML, Butler CM, Treston AM, Heine HS, Chirakul S, Schweizer HP, Louie A, Drusano GL, Zumbrun SD, Warfield KL.

Antimicrob Agents Chemother. 2019 Sep 23. pii: AAC.00834-19. doi: 10.1128/AAC.00834-19. [Epub ahead of print]

2.

Comparative immunogenicity and efficacy of thermostable (lyophilized) and liquid formulation of anthrax vaccine candidate AV7909.

Autumn Smiley M, Sanford DC, Triplett CA, Callahan D, Frolov V, Look J, Ruiz C, Reece JJ, Miles A, Ruiz E, Ionin B, Shearer JD, Savransky V.

Vaccine. 2019 Oct 8;37(43):6356-6361. doi: 10.1016/j.vaccine.2019.09.015. Epub 2019 Sep 14.

PMID:
31530467
3.

Efficacy of atropine sulfate/obidoxime chloride co-formulation against sarin exposure in guinea pigs.

Joosen MJA, Klaassen SD, Verheij E, van Groningen T, Cornelissen AS, Skiadopoulos MH, Cochrane L, Shearer JD.

Chem Biol Interact. 2018 Dec 25;296:34-42. doi: 10.1016/j.cbi.2018.09.004. Epub 2018 Sep 12.

PMID:
30217478
4.

Correlation between anthrax lethal toxin neutralizing antibody levels and survival in guinea pigs and nonhuman primates vaccinated with the AV7909 anthrax vaccine candidate.

Savransky V, Shearer JD, Gainey MR, Sanford DC, Sivko GS, Stark GV, Li N, Ionin B, Lacy MJ, Skiadopoulos MH.

Vaccine. 2017 Sep 5;35(37):4952-4959. doi: 10.1016/j.vaccine.2017.07.076. Epub 2017 Jul 31.

5.

Preclinical safety assessment of a recombinant plague vaccine (rF1V).

Price JL, Manetz TS, Shearer JD, House RV.

Int J Toxicol. 2013 Sep-Oct;32(5):327-35. doi: 10.1177/1091581813497405. Epub 2013 Aug 1.

PMID:
23908395
6.

Preclinical safety assessment of recombinant botulinum vaccine A/B (rBV A/B).

Shearer JD, Manetz TS, House RV.

Vaccine. 2012 Mar 2;30(11):1917-26. doi: 10.1016/j.vaccine.2012.01.035. Epub 2012 Jan 23.

PMID:
22269871
7.

Quantification of botulinum neurotoxin serotypes A and B from serum using mass spectrometry.

Parks BA, Shearer JD, Baudys J, Kalb SR, Sanford DC, Pirkle JL, Barr JR.

Anal Chem. 2011 Dec 1;83(23):9047-53. doi: 10.1021/ac201910q. Epub 2011 Nov 4.

PMID:
22017298
8.

Botulinum neurotoxin neutralizing activity of immune globulin (IG) purified from clinical volunteers vaccinated with recombinant botulinum vaccine (rBV A/B).

Shearer JD, Vassar ML, Swiderski W, Metcalfe K, Niemuth N, Henderson I.

Vaccine. 2010 Oct 21;28(45):7313-8. doi: 10.1016/j.vaccine.2010.08.076. Epub 2010 Sep 1.

PMID:
20816903
9.

Inhalational botulism in rhesus macaques exposed to botulinum neurotoxin complex serotypes A1 and B1.

Sanford DC, Barnewall RE, Vassar ML, Niemuth N, Metcalfe K, House RV, Henderson I, Shearer JD.

Clin Vaccine Immunol. 2010 Sep;17(9):1293-304. doi: 10.1128/CVI.00080-10. Epub 2010 Jul 21.

10.

An improved Francisella tularensis live vaccine strain (LVS) is well tolerated and highly immunogenic when administered to rabbits in escalating doses using various immunization routes.

Pasetti MF, Cuberos L, Horn TL, Shearer JD, Matthews SJ, House RV, Sztein MB.

Vaccine. 2008 Mar 25;26(14):1773-85. doi: 10.1016/j.vaccine.2008.01.005. Epub 2008 Jan 29.

11.

Biological activity of an intravenous preparation of human vaccinia immune globulin in mouse models of vaccinia virus infection.

Shearer JD, Siemann L, Gerkovich M, House RV.

Antimicrob Agents Chemother. 2005 Jul;49(7):2634-41.

12.

Portal donor-specific blood transfusion and mycophenolate mofetil allow steroid avoidance and tacrolimus dose reduction with sustained levels of chimerism in a pig model of intestinal transplantation.

Gruessner RW, Levay-Young BK, Nakhleh RE, Shearer JD, Dunning M, Nelson CM, Gruessner AC.

Transplantation. 2004 May 27;77(10):1500-6.

PMID:
15239611
13.

Intestinal graft versus native liver cytokine expression in a rat model of intestinal transplantation: effect of donor-specific cell augmentation.

Levay-Young B, Shearer JD, Gruessner AC, Kim SC, Nahkleh RE, Gruessner RW.

Transplant Proc. 2004 Mar;36(2):399-400.

PMID:
15050172
14.

Intestinal graft versus native liver cytokine expression in a rat model of intestinal transplantation with and without donor-specific cell augmentation.

Levay-Young B, Gruessner SE, Shearer JD, Cheol Kim S, Nahkleh RE, Gruessner RW.

J Surg Res. 2003 Sep;114(1):78-89.

PMID:
13678702
15.

Temporary treatment with sirolimus and low-trough cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated deferoxamine promotes islet engraftment in the preclinical pig model.

Shibata S, Matsumoto S, Sageshima J, Hiraoka K, Sutherland DE, Kirchhof N, Guo Z, Koyama K, Gilmore TR, Dunning M, Ansite JD, Shearer JD, Clemmings S, Hedlund BE, Sehgal SN, Hering BJ.

Transplant Proc. 2001 Feb-Mar;33(1-2):509. No abstract available.

PMID:
11266930
16.

Continuity between wound macrophage and fibroblast phenotype: analysis of wound fibroblast phagocytosis.

Arlein WJ, Shearer JD, Caldwell MD.

Am J Physiol. 1998 Oct;275(4):R1041-8. doi: 10.1152/ajpregu.1998.275.4.R1041.

PMID:
9756532
17.

Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56).

Shearer JD, Coulter CF, Engeland WC, Roth RA, Caldwell MD.

Am J Physiol. 1997 Oct;273(4):E657-64. doi: 10.1152/ajpendo.1997.273.4.E657.

PMID:
9357792
18.

Altered wound arginine metabolism by corticosterone and retinoic acid.

Ulland AE, Shearer JD, Coulter C, Caldwell MD.

J Surg Res. 1997 Jun;70(1):84-8.

PMID:
9228933
19.

Differential regulation of macrophage arginine metabolism: a proposed role in wound healing.

Shearer JD, Richards JR, Mills CD, Caldwell MD.

Am J Physiol. 1997 Feb;272(2 Pt 1):E181-90.

PMID:
9124321
20.

Wound fluid amino acid concentrations regulate the effect of epidermal growth factor on fibroblast replication.

Gartner MH, Shearer JD, Bereiter DF, Mills CD, Caldwell MD.

Surgery. 1991 Aug;110(2):448-55; discussion 455-6.

PMID:
1858053
21.

Glucose metabolism in injured tissue: a longitudinal study.

Daley JM, Shearer JD, Mastrofrancesco B, Caldwell MD.

Surgery. 1990 Feb;107(2):187-92.

PMID:
2405537
22.

Somatomedin-A inhibits glucagon-stimulated hepatic gluconeogenesis.

Amaral JF, O'Connor JA, Shearer JD, Hull SL, Caldwell MD.

J Trauma. 1989 Jun;29(6):842-6.

PMID:
2738982
23.

The effect of endotoxin on glucose metabolism in skeletal muscle requires the presence of plasma.

Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD.

Arch Surg. 1989 Jun;124(6):727-32.

PMID:
2658919
24.

Glucose uptake and flux through phosphofructokinase in wounded rat skeletal muscle.

Forster J, Morris AS, Shearer JD, Mastrofrancesco B, Inman KC, Lawler RG, Bowen W, Caldwell MD.

Am J Physiol. 1989 Jun;256(6 Pt 1):E788-97.

PMID:
2525343
25.

The temporal characteristics of the metabolic and endocrine response to injury.

Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD.

J Trauma. 1988 Sep;28(9):1335-52.

PMID:
2843656
26.

Glucose metabolism of injured skeletal muscle: the contribution of inflammatory cells.

Shearer JD, Amaral JF, Caldwell MD.

Circ Shock. 1988 Jul;25(3):131-8.

PMID:
3168170
27.

The relationship of purine metabolism to the macrophage-mediated increase of high energy phosphates in skeletal muscle.

Morris AS, Shearer JD, Forster J, Mastrofrancesco B, Henry W, Caldwell MD.

J Surg Res. 1986 Oct;41(4):339-46.

PMID:
3773494
28.

Can lactate be used as a fuel by wounded tissue?

Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD.

Surgery. 1986 Aug;100(2):252-61.

PMID:
3738754
29.

Alteration in pyruvate metabolism in the liver of tumor-bearing rats.

Shearer JD, Buzby GP, Mullen JL, Miller E, Caldwell MD.

Cancer Res. 1984 Oct;44(10):4443-6.

30.

The adolescent wheelchair athlete.

Shearer JD.

Pediatr Nurs. 1977 Sep-Oct;3(5):20-2. No abstract available.

PMID:
142957

Supplemental Content

Loading ...
Support Center