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BMI is a Better Predictor of Periprosthetic Joint Infection Risk Than Local Measures of Adipose Tissue After TKA.

Shearer J, Agius L, Burke N, Rahardja R, Young SW.

J Arthroplasty. 2020 Jan 24. pii: S0883-5403(20)30085-1. doi: 10.1016/j.arth.2020.01.048. [Epub ahead of print]


Perturbed mitochondrial dynamics, an emerging aspect of epithelial-microbe interactions.

McKay DM, Mancini NL, Shearer J, Shutt TE.

Am J Physiol Gastrointest Liver Physiol. 2020 Mar 2. doi: 10.1152/ajpgi.00031.2020. [Epub ahead of print]


Evaluation of Blast Overpressure Exposure Effects on Concentration of Antibiotics in Mice.

Antonic V, Sajja V, Sousa J, Nguyen K, Alamneh Y, Garry B, Medina-Rojas M, Wilder D, Vuong C, Potter B, Zurawski D, Shearer J, Black C, Demons S, Long J, Tyner S.

Mil Med. 2020 Jan 7;185(Suppl 1):256-262. doi: 10.1093/milmed/usz212.


Development of a guinea pig inhalational anthrax model for evaluation of post-exposure prophylaxis efficacy of anthrax vaccines.

Perry MR, Ionin B, Barnewall RE, Vassar ML, Reece JJ, Park S, Lemiale L, Skiadopoulos MH, Shearer JD, Savransky V.

Vaccine. 2020 Feb 28;38(10):2307-2314. doi: 10.1016/j.vaccine.2020.01.068. Epub 2020 Feb 3.


Maternal low-dose aspartame and stevia consumption with an obesogenic diet alters metabolism, gut microbiota and mesolimbic reward system in rat dams and their offspring.

Nettleton JE, Cho NA, Klancic T, Nicolucci AC, Shearer J, Borgland SL, Johnston LA, Ramay HR, Noye Tuplin E, Chleilat F, Thomson C, Mayengbam S, McCoy KD, Reimer RA.

Gut. 2020 Jan 29. pii: gutjnl-2018-317505. doi: 10.1136/gutjnl-2018-317505. [Epub ahead of print]


Efficacy of non-antibiotic treatment options for digital dermatitis on an organic dairy farm.

Paudyal S, Manriquez D, Velasquez A, Shearer JK, Plummer PJ, Melendez P, Callan RJ, Sorge US, Bothe H, Velez J, Pinedo PJ.

Vet J. 2020 Jan;255:105417. doi: 10.1016/j.tvjl.2019.105417. Epub 2019 Nov 29.


Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling.

Kumar M, Leon Coria A, Cornick S, Petri B, Mayengbam S, Jijon HB, Moreau F, Shearer J, Chadee K.

Nat Commun. 2020 Jan 24;11(1):483. doi: 10.1038/s41467-019-14182-2.


Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness.

Metrebian N, Weaver T, Pilling S, Goldsmith K, Carr E, Shearer J, Woolston-Thomas K, Tas B, Getty CA, Cooper C, van der Waal R, Kelleher M, Finch E, Bijral P, Taylor D, Scott J, Strang J.

Contemp Clin Trials Commun. 2019 Dec 10;17:100506. doi: 10.1016/j.conctc.2019.100506. eCollection 2020 Mar.


Reactivity of a biomimetic W(iv) bis-dithiolene complex with CO2 leading to formate production and structural rearrangement.

Seo J, Shearer J, Williard PG, Kim E.

Dalton Trans. 2019 Dec 3;48(47):17441-17444. doi: 10.1039/c9dt03906f.


Exercise and Dairy Protein have Distinct Effects on Indices of Liver and Systemic Lipid Metabolism.

Townsend LK, Gandhi S, Shamshoum H, Trottier SK, Mutch DM, Reimer RA, Shearer J, LeBlanc PJ, Wright DC.

Obesity (Silver Spring). 2020 Jan;28(1):97-105. doi: 10.1002/oby.22621. Epub 2019 Nov 15.


The impact of an integrated electronic immunization registry and logistics management information system (EIR-eLMIS) on vaccine availability in three regions in Tanzania: A pre-post and time-series analysis.

Gilbert SS, Bulula N, Yohana E, Thompson J, Beylerian E, Werner L, Shearer JC.

Vaccine. 2020 Jan 16;38(3):562-569. doi: 10.1016/j.vaccine.2019.10.059. Epub 2019 Nov 7.


Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study.

Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, Miyamoto R, Rho JM, Mickiewicz B, Dowlatabadi R, Vogel HJ, Korchemagin Y, Shearer J.

J Proteome Res. 2020 Jan 3;19(1):382-390. doi: 10.1021/acs.jproteome.9b00581. Epub 2019 Nov 22.


Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring.

Cleal JK, Bruce KD, Shearer JL, Thomas H, Plume J, Gregory L, Shepard JN, Spiers-Fitzgerald KL, Mani R, Lewis RM, Lillycrop KA, Hanson MA, Byrne CD, Cagampang FR.

Int J Mol Sci. 2019 Oct 30;20(21). pii: E5408. doi: 10.3390/ijms20215408.


GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Shearer JD, Saylor ML, Butler CM, Treston AM, Heine HS, Chirakul S, Schweizer HP, Louie A, Drusano GL, Zumbrun SD, Warfield KL.

Antimicrob Agents Chemother. 2019 Sep 23. pii: AAC.00834-19. doi: 10.1128/AAC.00834-19. [Epub ahead of print]


Distinct Gut Microbiota and Serum Metabolites in Response to Weight Loss Induced by Either Dairy or Exercise in a Rodent Model of Obesity.

Mayengbam S, Mickiewicz B, Trottier SK, Mu C, Wright DC, Reimer RA, Vogel HJ, Shearer J.

J Proteome Res. 2019 Nov 1;18(11):3867-3875. doi: 10.1021/acs.jproteome.9b00304. Epub 2019 Sep 27.


Comparative immunogenicity and efficacy of thermostable (lyophilized) and liquid formulation of anthrax vaccine candidate AV7909.

Autumn Smiley M, Sanford DC, Triplett CA, Callahan D, Frolov V, Look J, Ruiz C, Reece JJ, Miles A, Ruiz E, Ionin B, Shearer JD, Savransky V.

Vaccine. 2019 Oct 8;37(43):6356-6361. doi: 10.1016/j.vaccine.2019.09.015. Epub 2019 Sep 14.


Implications of Tennessee's Opioid Legislation for Neonatal Abstinence Syndrome.

Shearer JN, Erwin PC, Davis SK, Anderson JG, Lindley LC.

Policy Polit Nurs Pract. 2019 Aug;20(3):153-162. doi: 10.1177/1527154419864540. Epub 2019 Aug 7.


Dietary and Supplement-Based Complementary and Alternative Medicine Use in Pediatric Autism Spectrum Disorder.

Trudeau MS, Madden RF, Parnell JA, Gibbard WB, Shearer J.

Nutrients. 2019 Aug 1;11(8). pii: E1783. doi: 10.3390/nu11081783.


Clinical and cost implications of using immediate MRI in the management of patients with a suspected scaphoid fracture and negative radiographs results from the SMaRT trial.

Rua T, Malhotra B, Vijayanathan S, Hunter L, Peacock J, Shearer J, Goh V, McCrone P, Gidwani S.

Bone Joint J. 2019 Aug;101-B(8):984-994. doi: 10.1302/0301-620X.101B8.BJJ-2018-1590.R1.


Taking on pet obesity.

Angliss G, Ebers KL, Landis-Hanna A, Vale A, Stomack K, Niino T, O'Connell J, Janezcko S, Shearer JP, Lyle LT.

J Am Vet Med Assoc. 2019 Aug 15;255(4):421-422. doi: 10.2460/javma.255.4.421. No abstract available.


Refractory depression - cost-effectiveness of radically open dialectical behaviour therapy: findings of economic evaluation of RefraMED trial.

Shearer J, Lynch TR, Chamba R, Clarke S, Hempel RJ, Kingdon DG, O'Mahen H, Remington B, Rushbrook SC, Russell IT, Stanton M, Swales M, Watkins A, Whalley B, Byford S.

BJPsych Open. 2019 Sep;5(5):e64. doi: 10.1192/bjo.2019.57.


Refractory depression - mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms.

Lynch TR, Hempel RJ, Whalley B, Byford S, Chamba R, Clarke P, Clarke S, Kingdon DG, O'Mahen H, Remington B, Rushbrook SC, Shearer J, Stanton M, Swales M, Watkins A, Russell IT.

Br J Psychiatry. 2019 Jul 18:1-9. doi: 10.1192/bjp.2019.53. [Epub ahead of print]


Validation of an algorithm using inpatient electronic health records to determine the presence and severity of cirrhosis in patients with hepatocellular carcinoma in England: an observational study.

Driver RJ, Balachandrakumar V, Burton A, Shearer J, Downing A, Cross T, Morris E, Rowe IA.

BMJ Open. 2019 Jul 9;9(7):e028571. doi: 10.1136/bmjopen-2018-028571.


Hybrid gel electrophoresis using skin fibroblasts to aid in diagnosing mitochondrial disease.

Newell C, Khan A, Sinasac D, Shoffner J, Friederich MW, Van Hove JLK, Hume S, Shearer J, Sosova I.

Neurol Genet. 2019 May 1;5(3):e336. doi: 10.1212/NXG.0000000000000336. eCollection 2019 Jun.


Repeat-Dose Toxicity Study of a Lyophilized Recombinant Protective Antigen-Based Anthrax Vaccine Adjuvanted With CpG 7909.

Savransky V, Lacy M, Ionin B, Skiadopoulos MH, Shearer J.

Int J Toxicol. 2019 May/Jun;38(3):163-172. doi: 10.1177/1091581819848722.


Low-Dose Stevia (Rebaudioside A) Consumption Perturbs Gut Microbiota and the Mesolimbic Dopamine Reward System.

Nettleton JE, Klancic T, Schick A, Choo AC, Shearer J, Borgland SL, Chleilat F, Mayengbam S, Reimer RA.

Nutrients. 2019 May 31;11(6). pii: E1248. doi: 10.3390/nu11061248.


Role of O-Antigen in Response to Mechanical Stress of the E. coli Outer Membrane: Insights from Coarse-Grained MD Simulations.

Jefferies D, Shearer J, Khalid S.

J Phys Chem B. 2019 May 2;123(17):3567-3575. doi: 10.1021/acs.jpcb.8b12168. Epub 2019 Apr 23.


Longitudinal investigation of haematological alterations among permethrin-exposed pesticide applicators in the Biomarkers of Exposure and Effect in Agriculture study.

Shearer JJ, Beane Freeman LE, Liu D, Andreotti G, Hamilton J, Happel J, Lynch CF, Alavanja MC, Hofmann JN.

Occup Environ Med. 2019 Jul;76(7):467-470. doi: 10.1136/oemed-2018-105559. Epub 2019 Apr 8.


Effects of Caffeine on Exertion, Skill Performance, and Physicality in Ice Hockey.

Madden RF, Erdman KA, Shearer J, Spriet LL, Ferber R, Kolstad AT, Bigg JL, Gamble ASD, Benson LC.

Int J Sports Physiol Perform. 2019 Oct 8:1-8. doi: 10.1123/ijspp.2019-0130. [Epub ahead of print]


Efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy: a pragmatic, open-label, randomised controlled trial.

Marsden J, Stillwell G, James K, Shearer J, Byford S, Hellier J, Kelleher M, Kelly J, Murphy C, Mitcheson L.

Lancet Psychiatry. 2019 May;6(5):391-402. doi: 10.1016/S2215-0366(19)30097-5. Epub 2019 Apr 2.


Diving behaviour of Cuvier's beaked whales (Ziphius cavirostris) off Cape Hatteras, North Carolina.

Shearer JM, Quick NJ, Cioffi WR, Baird RW, Webster DL, Foley HJ, Swaim ZT, Waples DM, Bell JT, Read AJ.

R Soc Open Sci. 2019 Feb 6;6(2):181728. doi: 10.1098/rsos.181728. eCollection 2019 Feb.


Outer Membrane Proteins OmpA, FhuA, OmpF, EstA, BtuB, and OmpX Have Unique Lipopolysaccharide Fingerprints.

Shearer J, Jefferies D, Khalid S.

J Chem Theory Comput. 2019 Apr 9;15(4):2608-2619. doi: 10.1021/acs.jctc.8b01059. Epub 2019 Mar 21.


Redefining vaccination coverage and timeliness measures using electronic immunization registry data in low- and middle-income countries.

Dolan SB, Carnahan E, Shearer JC, Beylerian EN, Thompson J, Gilbert SS, Werner L, Ryman TK.

Vaccine. 2019 Mar 22;37(13):1859-1867. doi: 10.1016/j.vaccine.2019.02.017. Epub 2019 Feb 23.


Skin and Soft Tissue Models for Acinetobacter baumannii Infection.

Zurawski DV, Banerjee J, Alamneh YA, Shearer JP, Demons ST.

Methods Mol Biol. 2019;1946:271-287. doi: 10.1007/978-1-4939-9118-1_25.


A Biochemical Nickel(I) State Supports Nucleophilic Alkyl Addition: A Roadmap for Methyl Reactivity in Acetyl Coenzyme A Synthase.

Manesis AC, Musselman BW, Keegan BC, Shearer J, Lehnert N, Shafaat HS.

Inorg Chem. 2019 Jul 15;58(14):8969-8982. doi: 10.1021/acs.inorgchem.8b03546. Epub 2019 Feb 21.


Reduction of CO2 by a masked two-coordinate cobalt(i) complex and characterization of a proposed oxodicobalt(ii) intermediate.

Roy L, Al-Afyouni MH, DeRosha DE, Mondal B, DiMucci IM, Lancaster KM, Shearer J, Bill E, Brennessel WW, Neese F, Ye S, Holland PL.

Chem Sci. 2018 Nov 9;10(3):918-929. doi: 10.1039/c8sc02599a. eCollection 2019 Jan 21.


Cost-effectiveness analysis of telephone cognitive-behaviour therapy for adolescents with obsessive-compulsive disorder.

Tie H, Krebs G, Lang K, Shearer J, Turner C, Mataix-Cols D, Lovell K, Heyman I, Byford S.

BJPsych Open. 2019 Jan;5(1):e7. doi: 10.1192/bjo.2018.73.


A Porcine Wound Model of Acinetobacter baumannii Infection.

Zurawski DV, Black CC, Alamneh YA, Biggemann L, Banerjee J, Thompson MG, Wise MC, Honnold CL, Kim RK, Paranavitana C, Shearer JP, Tyner SD, Demons ST.

Adv Wound Care (New Rochelle). 2019 Jan 1;8(1):14-27. doi: 10.1089/wound.2018.0786. Epub 2019 Jan 5.


Extended-release naltrexone versus standard oral naltrexone versus placebo for opioid use disorder: the NEAT three-arm RCT.

Strang J, Kelleher M, Mayet S, Day E, Hellier J, Byford S, Murphy C, McLennan B, Shearer J, Ryan E, Marsden J.

Health Technol Assess. 2019 Jan;23(3):1-72. doi: 10.3310/hta23030.


Metabolic consequences of discretionary fortified beverage consumption containing excessive vitamin B levels in adolescents.

Mayengbam S, Virtanen H, Hittel DS, Elliott C, Reimer RA, Vogel HJ, Shearer J.

PLoS One. 2019 Jan 17;14(1):e0209913. doi: 10.1371/journal.pone.0209913. eCollection 2019.


Researcher and policymaker dialogue: the Policy BUDDIES Project in Western Cape Province, South Africa.

Young T, Shearer JC, Naude C, Kredo T, Wiysonge CS, Garner P.

BMJ Glob Health. 2018 Dec 14;3(6):e001130. doi: 10.1136/bmjgh-2018-001130. eCollection 2018.


Impact of dietary fiber supplementation on modulating microbiota-host-metabolic axes in obesity.

Mayengbam S, Lambert JE, Parnell JA, Tunnicliffe JM, Nicolucci AC, Han J, Sturzenegger T, Shearer J, Mickiewicz B, Vogel HJ, Madsen KL, Reimer RA.

J Nutr Biochem. 2019 Feb;64:228-236. doi: 10.1016/j.jnutbio.2018.11.003. Epub 2018 Nov 26.


Radically open dialectical behaviour therapy for refractory depression: the RefraMED RCT.

Lynch TR, Hempel RJ, Whalley B, Byford S, Chamba R, Clarke P, Clarke S, Kingdon D, O’Mahen H, Remington B, Rushbrook SC, Shearer J, Stanton M, Swales M, Watkins A, Russell IT.

Southampton (UK): NIHR Journals Library; 2018 Dec.


Mesenchymal Stem Cells Shift Mitochondrial Dynamics and Enhance Oxidative Phosphorylation in Recipient Cells.

Newell C, Sabouny R, Hittel DS, Shutt TE, Khan A, Klein MS, Shearer J.

Front Physiol. 2018 Nov 13;9:1572. doi: 10.3389/fphys.2018.01572. eCollection 2018.


Evaluation of Dietary Supplement Use in Wheelchair Rugby Athletes.

Madden RF, Shearer J, Legg D, Parnell JA.

Nutrients. 2018 Dec 11;10(12). pii: E1958. doi: 10.3390/nu10121958.


Plasma-derived cell-free mitochondrial DNA: A novel non-invasive methodology to identify mitochondrial DNA haplogroups in humans.

Newell C, Hume S, Greenway SC, Podemski L, Shearer J, Khan A.

Mol Genet Metab. 2018 Dec;125(4):332-337. doi: 10.1016/j.ymgme.2018.10.002. Epub 2018 Oct 16.


Attributes and Actions Required to Advance Quality and Safety in Hospitals: Insights from Nurse Executives.

Jeffs L, Baker GR, Taggar R, Hubley P, Richards J, Merkley J, Shearer J, Webster H, Dizon M, Fong JH.

Nurs Leadersh (Tor Ont). 2018 Jun;31(2):20-31. doi: 10.12927/cjnl.2018.25606.


Association of physical activity and sedentary time with blood cell counts: National Health and Nutrition Survey 2003-2006.

Willis EA, Shearer JJ, Matthews CE, Hofmann JN.

PLoS One. 2018 Sep 25;13(9):e0204277. doi: 10.1371/journal.pone.0204277. eCollection 2018.


Efficacy of atropine sulfate/obidoxime chloride co-formulation against sarin exposure in guinea pigs.

Joosen MJA, Klaassen SD, Verheij E, van Groningen T, Cornelissen AS, Skiadopoulos MH, Cochrane L, Shearer JD.

Chem Biol Interact. 2018 Dec 25;296:34-42. doi: 10.1016/j.cbi.2018.09.004. Epub 2018 Sep 12.


Non-invasive prediction of oesophageal varices in patients with cirrhosis secondary to non-alcoholic fatty liver disease.

Shearer J, Chizhande D, Jones R, Rowe IA.

J Hepatol. 2018 Nov;69(5):1202-1203. doi: 10.1016/j.jhep.2018.08.003. Epub 2018 Sep 8. No abstract available.


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