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Predicting the effects of supplemental EPA and DHA on the omega-3 index.

Walker RE, Jackson KH, Tintle NL, Shearer GC, Bernasconi A, Masson S, Latini R, Heydari B, Kwong RY, Flock M, Kris-Etherton PM, Hedengran A, Carney RM, Skulas-Ray A, Gidding SS, Dewell A, Gardner CD, Grenon SM, Sarter B, Newman JW, Pedersen TL, Larson MK, Harris WS.

Am J Clin Nutr. 2019 Aug 8. pii: nqz161. doi: 10.1093/ajcn/nqz161. [Epub ahead of print]


Dyadic Decision-Making in Advanced Parkinson's Disease: A Mixed Methods Study.

Habermann B, Shin JY, Shearer G.

West J Nurs Res. 2019 Jul 13:193945919864429. doi: 10.1177/0193945919864429. [Epub ahead of print]


Predicting Risk for Incident Heart Failure With Omega-3 Fatty Acids: From MESA.

Block RC, Liu L, Herrington DM, Huang S, Tsai MY, O'Connell TD, Shearer GC.

JACC Heart Fail. 2019 Aug;7(8):651-661. doi: 10.1016/j.jchf.2019.03.008. Epub 2019 Jul 10.


Walnuts change lipoprotein composition suppressing TNFα-stimulated cytokine production by diabetic adipocyte.

Borkowski K, Yim SJ, Holt RR, Hackman RM, Keen CL, Newman JW, Shearer GC.

J Nutr Biochem. 2019 Jun;68:51-58. doi: 10.1016/j.jnutbio.2019.03.004. Epub 2019 Mar 28.


Two nights of recovery sleep restores the dynamic lipemic response, but not the reduction of insulin sensitivity, induced by five nights of sleep restriction.

Ness KM, Strayer SM, Nahmod NG, Chang AM, Buxton OM, Shearer GC.

Am J Physiol Regul Integr Comp Physiol. 2019 Jun 1;316(6):R697-R703. doi: 10.1152/ajpregu.00336.2018. Epub 2019 Mar 20.


Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation.

Singh V, Yeoh BS, Walker RE, Xiao X, Saha P, Golonka RM, Cai J, Bretin ACA, Cheng X, Liu Q, Flythe MD, Chassaing B, Shearer GC, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Gut. 2019 Jan 22. pii: gutjnl-2018-316250. doi: 10.1136/gutjnl-2018-316250. [Epub ahead of print]


Tree Nut Consumption and Adipose Tissue Mass: Mechanisms of Action.

Tindall AM, Petersen KS, Lamendella R, Shearer GC, Murray-Kolb LE, Proctor DN, Kris-Etherton PM.

Curr Dev Nutr. 2018 Aug 3;2(11):nzy069. doi: 10.1093/cdn/nzy069. eCollection 2018 Nov. Review.


An overview of the biologic effects of omega-6 oxylipins in humans.

Shearer GC, Walker RE.

Prostaglandins Leukot Essent Fatty Acids. 2018 Oct;137:26-38. doi: 10.1016/j.plefa.2018.06.005. Epub 2018 Jun 30. Review.


Tea Consumption and Longitudinal Change in High-Density Lipoprotein Cholesterol Concentration in Chinese Adults.

Huang S, Li J, Wu Y, Ranjbar S, Xing A, Zhao H, Wang Y, Shearer GC, Bao L, Lichtenstein AH, Wu S, Gao X.

J Am Heart Assoc. 2018 Jun 25;7(13). pii: e008814. doi: 10.1161/JAHA.118.008814.


The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients.

Sthoeger Z, Sharabi A, Asher I, Zinger H, Segal R, Shearer G, Elkayam O, Mozes E.

Clin Immunol. 2018 Jul;192:85-91. doi: 10.1016/j.clim.2018.05.001. Epub 2018 May 4.


A genome-wide association study of red-blood cell fatty acids and ratios incorporating dietary covariates: Framingham Heart Study Offspring Cohort.

Kalsbeek A, Veenstra J, Westra J, Disselkoen C, Koch K, McKenzie KA, O'Bott J, Vander Woude J, Fischer K, Shearer GC, Harris WS, Tintle NL.

PLoS One. 2018 Apr 13;13(4):e0194882. doi: 10.1371/journal.pone.0194882. eCollection 2018.


Subcellular compartmentalization of proximal Gαq-receptor signaling produces unique hypertrophic phenotypes in adult cardiac myocytes.

Dahl EF, Wu SC, Healy CL, Harsch BA, Shearer GC, O'Connell TD.

J Biol Chem. 2018 Jun 8;293(23):8734-8749. doi: 10.1074/jbc.RA118.002283. Epub 2018 Apr 2.


Induction and Measurement of Cytotoxic T Lymphocyte Activity.

Wonderlich J, Shearer G, Livingstone A, Brooks A, Soloski MJ, Presby MM.

Curr Protoc Immunol. 2018 Feb 21;120:3.11.1-3.11.29. doi: 10.1002/cpim.38.


Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids.

Shearer GC, Borkowski K, Puumala SL, Harris WS, Pedersen TL, Newman JW.

Prostaglandins Leukot Essent Fatty Acids. 2018 Jan;128:1-10. doi: 10.1016/j.plefa.2017.10.006. Epub 2017 Nov 11.


A bio-based pro-antimicrobial polymer network via degradable acetal linkages.

Amato DV, Amato DN, Blancett LT, Mavrodi OV, Martin WB, Swilley SN, Sandoz MJ, Shearer G, Mavrodi DV, Patton DL.

Acta Biomater. 2018 Feb;67:196-205. doi: 10.1016/j.actbio.2017.12.016. Epub 2017 Dec 18.


Analyzing metabolomics data for association with genotypes using two-component Gaussian mixture distributions.

Westra J, Hartman N, Lake B, Shearer G, Tintle N.

Pac Symp Biocomput. 2018;23:496-506.


Apolipoprotein A-I exchange is impaired in metabolic syndrome patients asymptomatic for diabetes and cardiovascular disease.

Borja MS, Hammerson B, Tang C, Savinova OV, Shearer GC, Oda MN.

PLoS One. 2017 Aug 2;12(8):e0182217. doi: 10.1371/journal.pone.0182217. eCollection 2017.


Pitfalls in metal-organic framework crystallography: towards more accurate crystal structures.

Øien-Ødegaard S, Shearer GC, Wragg DS, Lillerud KP.

Chem Soc Rev. 2017 Aug 14;46(16):4867-4876. doi: 10.1039/c6cs00533k.


Smell and Taste Dysfunction Is Associated with Higher Serum Total Cholesterol Concentrations in Chinese Adults.

Huang Z, Huang S, Cong H, Li Z, Li J, Keller KL, Shearer GC, Kris-Etherton PM, Wu S, Gao X.

J Nutr. 2017 Aug;147(8):1546-1551. doi: 10.3945/jn.117.250480. Epub 2017 Jun 14.


Oleic acid-derived oleoylethanolamide: A nutritional science perspective.

Bowen KJ, Kris-Etherton PM, Shearer GC, West SG, Reddivari L, Jones PJH.

Prog Lipid Res. 2017 Jul;67:1-15. doi: 10.1016/j.plipres.2017.04.001. Epub 2017 Apr 5. Review.


Longitudinal study of alcohol consumption and HDL concentrations: a community-based study.

Huang S, Li J, Shearer GC, Lichtenstein AH, Zheng X, Wu Y, Jin C, Wu S, Gao X.

Am J Clin Nutr. 2017 Apr;105(4):905-912. doi: 10.3945/ajcn.116.144832. Epub 2017 Mar 1.


ω3-Polyunsaturated fatty acids for heart failure: Effects of dose on efficacy and novel signaling through free fatty acid receptor 4.

O'Connell TD, Block RC, Huang SP, Shearer GC.

J Mol Cell Cardiol. 2017 Feb;103:74-92. doi: 10.1016/j.yjmcc.2016.12.003. Epub 2016 Dec 14. Review.


The Mould-specific M46 gene is not essential for yeast-mould dimorphism in the pathogenic fungus Histoplasma capsulatum.

Crossley D, Naraharisetty V, Shearer G Jr.

Med Mycol. 2016 Nov 1;54(8):876-84. doi: 10.1093/mmy/myw040. Epub 2016 Jun 22.


Curing HIV/AIDS beyond hematopoietic stem cell transplant.

Shearer GM, Clerici M, Graham DR, Boasso A.

AIDS. 2015 Nov;29(17):2364-6. doi: 10.1097/QAD.0000000000000861. No abstract available.


Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.

Singh V, Chassaing B, Zhang L, San Yeoh B, Xiao X, Kumar M, Baker MT, Cai J, Walker R, Borkowski K, Harvatine KJ, Singh N, Shearer GC, Ntambi JM, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Cell Metab. 2015 Dec 1;22(6):983-96. doi: 10.1016/j.cmet.2015.09.028. Epub 2015 Oct 29.


EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4.

Eclov JA, Qian Q, Redetzke R, Chen Q, Wu SC, Healy CL, Ortmeier SB, Harmon E, Shearer GC, O'Connell TD.

J Lipid Res. 2015 Dec;56(12):2297-308. doi: 10.1194/jlr.M062034. Epub 2015 Oct 4.


Effects of short-term walnut consumption on human microvascular function and its relationship to plasma epoxide content.

Holt RR, Yim SJ, Shearer GC, Hackman RM, Djurica D, Newman JW, Shindel AW, Keen CL.

J Nutr Biochem. 2015 Dec;26(12):1458-66. doi: 10.1016/j.jnutbio.2015.07.012. Epub 2015 Aug 1.


Effects of niacin and omega-3 fatty acids on the apolipoproteins in overweight patients with elevated triglycerides and reduced HDL cholesterol.

Savinova OV, Fillaus K, Harris WS, Shearer GC.

Atherosclerosis. 2015 Jun;240(2):520-5. doi: 10.1016/j.atherosclerosis.2015.04.793. Epub 2015 Apr 22.


A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.

Tintle NL, Pottala JV, Lacey S, Ramachandran V, Westra J, Rogers A, Clark J, Olthoff B, Larson M, Harris W, Shearer GC.

Prostaglandins Leukot Essent Fatty Acids. 2015 Mar;94:65-72. doi: 10.1016/j.plefa.2014.11.007. Epub 2014 Dec 2.


Effect of omega-3 fatty acid ethyl esters on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects.

Newman JW, Pedersen TL, Brandenburg VR, Harris WS, Shearer GC.

PLoS One. 2014 Nov 13;9(11):e111471. doi: 10.1371/journal.pone.0111471. eCollection 2014.


Carbon dioxide adsorption in amine-functionalized mixed-ligand metal-organic frameworks of UiO-66 topology.

Ethiraj J, Albanese E, Civalleri B, Vitillo JG, Bonino F, Chavan S, Shearer GC, Lillerud KP, Bordiga S.

ChemSusChem. 2014 Dec;7(12):3382-8. doi: 10.1002/cssc.201402694. Epub 2014 Oct 10.


Omega-6 fatty acids and cardiovascular disease: friend, not foe?

Harris WS, Shearer GC.

Circulation. 2014 Oct 28;130(18):1562-4. doi: 10.1161/CIRCULATIONAHA.114.012534. Epub 2014 Aug 26. No abstract available.


Synthesis and characterization of amine-functionalized mixed-ligand metal-organic frameworks of UiO-66 topology.

Chavan SM, Shearer GC, Svelle S, Olsbye U, Bonino F, Ethiraj J, Lillerud KP, Bordiga S.

Inorg Chem. 2014 Sep 15;53(18):9509-15. doi: 10.1021/ic500607a. Epub 2014 Aug 22.


Reduced apolipoprotein glycosylation in patients with the metabolic syndrome.

Savinova OV, Fillaus K, Jing L, Harris WS, Shearer GC.

PLoS One. 2014 Aug 12;9(8):e104833. doi: 10.1371/journal.pone.0104833. eCollection 2014.


Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline.

Drewes JL, Szeto GL, Engle EL, Liao Z, Shearer GM, Zink MC, Graham DR.

PLoS One. 2014 Apr 14;9(4):e94375. doi: 10.1371/journal.pone.0094375. eCollection 2014.


Treatment with omega-3 fatty acid ethyl-ester alters fatty acid composition of lipoproteins in overweight or obese adults with insulin resistance.

Augustine AH, Lowenstein LM, Harris WS, Shearer GC, Block RC.

Prostaglandins Leukot Essent Fatty Acids. 2014 Feb-Mar;90(2-3):69-75. doi: 10.1016/j.plefa.2013.12.003. Epub 2013 Dec 18.


Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.

Vaccari M, Fenizia C, Ma ZM, Hryniewicz A, Boasso A, Doster MN, Miller CJ, Lindegardh N, Tarning J, Landay AL, Shearer GM, Franchini G.

AIDS Res Hum Retroviruses. 2014 Apr;30(4):355-62. doi: 10.1089/AID.2013.0218. Epub 2013 Dec 24.


HDL-apoA-I exchange: rapid detection and association with atherosclerosis.

Borja MS, Zhao L, Hammerson B, Tang C, Yang R, Carson N, Fernando G, Liu X, Budamagunta MS, Genest J, Shearer GC, Duclos F, Oda MN.

PLoS One. 2013 Aug 28;8(8):e71541. doi: 10.1371/journal.pone.0071541. eCollection 2013.


Stability vs. reactivity: understanding the adsorption properties of Ni3(BTP)2 by experimental and computational methods.

Shearer GC, Colombo V, Chavan S, Albanese E, Civalleri B, Maspero A, Bordiga S.

Dalton Trans. 2013 May 14;42(18):6450-8. doi: 10.1039/c3dt32944e.


Effects of prescription niacin and omega-3 fatty acids on lipids and vascular function in metabolic syndrome: a randomized controlled trial.

Shearer GC, Pottala JV, Hansen SN, Brandenburg V, Harris WS.

J Lipid Res. 2012 Nov;53(11):2429-35. doi: 10.1194/jlr.P022392. Epub 2012 Aug 14.


Proteinuria decreases tissue lipoprotein receptor levels resulting in altered lipoprotein structure and increasing lipid levels.

Wang L, Shearer GC, Budamagunta MS, Voss JC, Molfino A, Kaysen GA.

Kidney Int. 2012 Nov;82(9):990-9. doi: 10.1038/ki.2012.244. Epub 2012 Jul 11. Retraction in: Kidney Int. 2013 Jun;83(6):1207.


Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers.

Keenan AH, Pedersen TL, Fillaus K, Larson MK, Shearer GC, Newman JW.

J Lipid Res. 2012 Aug;53(8):1662-9. doi: 10.1194/jlr.P025577. Epub 2012 May 24.


The Effects of EPA+DHA and Aspirin on Inflammatory Cytokines and Angiogenesis Factors.

Block RC, Dier U, Calderonartero P, Shearer GC, Kakinami L, Larson MK, Harris WS, Georas S, Mousa SA.

World J Cardiovasc Dis. 2012 Jan 1;2(1):14-19. Epub 2011 Dec 30.


Cis-vaccenic acid and the Framingham risk score predict chronic kidney disease: the multi-ethnic study of atherosclerosis (MESA).

Block R, Kakinami L, Liebman S, Shearer GC, Kramer H, Tsai M.

Prostaglandins Leukot Essent Fatty Acids. 2012 Apr;86(4-5):175-82. doi: 10.1016/j.plefa.2012.02.009. Epub 2012 Mar 13.


Acetylene adsorption on CPO-27-M metal-organic frameworks (M=Fe, Co and Ni).

Chavan SM, Shearer GC, Bloch E, Bordiga S.

Chemphyschem. 2012 Feb;13(2):445-8. doi: 10.1002/cphc.201100950. Epub 2012 Jan 11. No abstract available.


Fish oil -- how does it reduce plasma triglycerides?

Shearer GC, Savinova OV, Harris WS.

Biochim Biophys Acta. 2012 May;1821(5):843-51. doi: 10.1016/j.bbalip.2011.10.011. Epub 2011 Oct 25.


Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade.

Vaccari M, Boasso A, Fenizia C, Fuchs D, Hryniewicz A, Morgan T, Weiss D, Doster MN, Heraud JM, Shearer GM, Franchini G.

J Virol. 2012 Jan;86(1):108-13. doi: 10.1128/JVI.05609-11. Epub 2011 Oct 19.


Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis.

Boasso A, Royle CM, Doumazos S, Aquino VN, Biasin M, Piacentini L, Tavano B, Fuchs D, Mazzotta F, Lo Caputo S, Shearer GM, Clerici M, Graham DR.

Blood. 2011 Nov 10;118(19):5152-62. doi: 10.1182/blood-2011-03-344218. Epub 2011 Sep 19.


Alloantigen-based AIDS vaccine: revisiting a "rightfully" discarded promising strategy.

Shearer GM, Boasso A.

F1000 Med Rep. 2011;3:12. doi: 10.3410/M3-12. Epub 2011 Jun 1.


Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality.

Shearer GC, Carrero JJ, Heimbürger O, Barany P, Stenvinkel P.

J Ren Nutr. 2012 Mar;22(2):277-83. doi: 10.1053/j.jrn.2011.05.005. Epub 2011 Jul 20.


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