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Items: 24

1.

Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.

Bradford EM, Ryu SH, Singh AP, Lee G, Goretsky T, Sinh P, Williams DB, Cloud AL, Gounaris E, Patel V, Lamping OF, Lynch EB, Moyer MP, De Plaen IG, Shealy DJ, Yang GY, Barrett TA.

J Immunol. 2017 Sep 1;199(5):1886-1897. doi: 10.4049/jimmunol.1601066. Epub 2017 Jul 26.

2.

Discovery and mechanism of ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders.

Benson JM, Peritt D, Scallon BJ, Heavner GA, Shealy DJ, Giles-Komar JM, Mascelli MA.

MAbs. 2011 Nov-Dec;3(6):535-45. doi: 10.4161/mabs.3.6.17815. Epub 2011 Nov 1. Review.

3.

Evaluation of an anti-tumor necrosis factor therapeutic in a mouse model of Niemann-Pick C liver disease.

Vincent M, Sayre NL, Graham MJ, Crooke RM, Shealy DJ, Liscum L.

PLoS One. 2010 Sep 23;5(9):e12941. doi: 10.1371/journal.pone.0012941.

4.

Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α.

Shealy DJ, Cai A, Staquet K, Baker A, Lacy ER, Johns L, Vafa O, Gunn G 3rd, Tam S, Sague S, Wang D, Brigham-Burke M, Dalmonte P, Emmell E, Pikounis B, Bugelski PJ, Zhou H, Scallon BJ, Giles-Komar J.

MAbs. 2010 Jul-Aug;2(4):428-39. Epub 2010 Jul 1.

5.

TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice.

Baluk P, Yao LC, Feng J, Romano T, Jung SS, Schreiter JL, Yan L, Shealy DJ, McDonald DM.

J Clin Invest. 2009 Oct;119(10):2954-64. doi: 10.1172/JCI37626. Epub 2009 Sep 14.

6.

Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice.

Warren MA, Shoemaker SF, Shealy DJ, Bshar W, Ip MM.

Mol Cancer Ther. 2009 Sep;8(9):2655-63. doi: 10.1158/1535-7163.MCT-09-0358. Epub 2009 Sep 15.

7.

Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging.

Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Calvi LM, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM.

Arthritis Rheum. 2008 Jul;58(7):2019-29. doi: 10.1002/art.23546.

8.

Anti-TNF antibodies: lessons from the past, roadmap for the future.

Shealy DJ, Visvanathan S.

Handb Exp Pharmacol. 2008;(181):101-29. Review.

PMID:
18071943
9.

Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography.

Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM.

Arthritis Rheum. 2007 Dec;56(12):4024-37.

10.

MRI and quantification of draining lymph node function in inflammatory arthritis.

Proulx ST, Kwok E, You Z, Beck CA, Shealy DJ, Ritchlin CT, Boyce BF, Xing L, Schwarz EM.

Ann N Y Acad Sci. 2007 Nov;1117:106-23. Epub 2007 Jul 23.

PMID:
17646265
11.

Induction of dendritic cell maturation by IL-18.

Li J, Mbow ML, Sun L, Li L, Yang G, Griswold DE, Schantz A, Shealy DJ, Goletz TJ, Wan J, Peritt D.

Cell Immunol. 2004 Feb;227(2):103-8.

PMID:
15135292
12.

An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors.

Scott KA, Moore RJ, Arnott CH, East N, Thompson RG, Scallon BJ, Shealy DJ, Balkwill FR.

Mol Cancer Ther. 2003 May;2(5):445-51.

13.

Anti-TNF-alpha antibody allows healing of joint damage in polyarthritic transgenic mice.

Shealy DJ, Wooley PH, Emmell E, Volk A, Rosenberg A, Treacy G, Wagner CL, Mayton L, Griswold DE, Song XY.

Arthritis Res. 2002;4(5):R7. Epub 2002 Jun 28.

14.
15.

The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo.

Siegel SA, Shealy DJ, Nakada MT, Le J, Woulfe DS, Probert L, Kollias G, Ghrayeb J, Vilcek J, Daddona PE.

Cytokine. 1995 Jan;7(1):15-25.

PMID:
7538333
16.

Human monoclonal antibody HA-1A binds to endotoxin via an epitope in the lipid A domain of lipopolysaccharide.

Bogard WC Jr, Siegel SA, Leone AO, Damiano E, Shealy DJ, Ely TM, Frederick B, Mascelli MA, Siegel RC, Machielse B, et al.

J Immunol. 1993 May 15;150(10):4438-49.

PMID:
7683319
17.

Reactivity of the human antiendotoxin immunoglobulin M monoclonal antibody HA-1A with lipopolysaccharides from rough and smooth gram-negative organisms.

Mascelli MA, Frederick B, Ely T, Neblock DS, Shealy DJ, Pak KY, Daddona PE.

Infect Immun. 1993 May;61(5):1756-63.

18.

Rapid infarct imaging with a technetium-99m-labeled antimyosin recombinant single-chain Fv: evaluation in a canine model of acute myocardial infarction.

Nedelman MA, Shealy DJ, Boulin R, Brunt E, Seasholtz JI, Allen IE, McCartney JE, Warren FD, Oppermann H, Pang RH, et al.

J Nucl Med. 1993 Feb;34(2):234-41.

19.

Evaluation of indium-111-labeled anti-fibrin antibody for imaging vascular thrombi.

Knight LC, Maurer AH, Ammar IA, Shealy DJ, Mattis JA.

J Nucl Med. 1988 Apr;29(4):494-502.

20.

Radiosensitizer conjugation to the carcinoma 19-9 monoclonal antibody.

Borlinghaus KP, Fitzpatrick DA, Heindel ND, Mattis JA, Mease BA, Schray KJ, Shealy DJ, Walton HL Jr, Woo DV.

Cancer Res. 1987 Aug 1;47(15):4071-5.

22.

Human cells contain two forms of pp60c-src.

Shealy DJ, Erikson RL.

Nature. 1981 Oct 22;293(5834):666-9. No abstract available.

PMID:
6169996
23.

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