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Items: 10

1.

Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation.

Kim R, Sheaffer KL, Choi I, Won KJ, Kaestner KH.

Genes Dev. 2016 Nov 1;30(21):2433-2442. Epub 2016 Nov 17.

2.

DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation.

Sheaffer KL, Elliott EN, Kaestner KH.

Cancer Prev Res (Phila). 2016 Jul;9(7):534-46. doi: 10.1158/1940-6207.CAPR-15-0349. Epub 2016 Feb 16.

3.

The 'de novo' DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium.

Elliott EN, Sheaffer KL, Kaestner KH.

Elife. 2016 Jan 25;5. pii: e12975. doi: 10.7554/eLife.12975.

4.

ChIP-Seq: Library Preparation and Sequencing.

Sheaffer KL, Schug J.

Methods Mol Biol. 2016;1402:101-117. doi: 10.1007/978-1-4939-3378-5_9.

PMID:
26721486
5.

The BisPCR(2) method for targeted bisulfite sequencing.

Bernstein DL, Kameswaran V, Le Lay JE, Sheaffer KL, Kaestner KH.

Epigenetics Chromatin. 2015 Aug 1;8:27. doi: 10.1186/s13072-015-0020-x. eCollection 2015.

6.

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.

Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH.

Development. 2015 Jun 15;142(12):2163-72. doi: 10.1242/dev.117341. Epub 2015 May 28.

7.

DNA methylation is required for the control of stem cell differentiation in the small intestine.

Sheaffer KL, Kim R, Aoki R, Elliott EN, Schug J, Burger L, Schübeler D, Kaestner KH.

Genes Dev. 2014 Mar 15;28(6):652-64. doi: 10.1101/gad.230318.113.

8.

Transcriptional networks in liver and intestinal development.

Sheaffer KL, Kaestner KH.

Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a008284. doi: 10.1101/cshperspect.a008284. Review.

9.

Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response.

Zhong M, Niu W, Lu ZJ, Sarov M, Murray JI, Janette J, Raha D, Sheaffer KL, Lam HY, Preston E, Slightham C, Hillier LW, Brock T, Agarwal A, Auerbach R, Hyman AA, Gerstein M, Mango SE, Kim SK, Waterston RH, Reinke V, Snyder M.

PLoS Genet. 2010 Feb 19;6(2):e1000848. doi: 10.1371/journal.pgen.1000848.

10.

The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.

Sheaffer KL, Updike DL, Mango SE.

Curr Biol. 2008 Sep 23;18(18):1355-64. doi: 10.1016/j.cub.2008.07.097.

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