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Items: 1 to 50 of 115

1.

Bifidobacterium animalis subspecies lactis modulates the local immune response and glucose uptake in the small intestine of juvenile pigs infected with the parasitic nematode Ascaris suum.

Solano-Aguilar G, Shea-Donohue T, Madden KB, Quinoñes A, Beshah E, Lakshman S, Xie Y, Dawson H, Urban JF.

Gut Microbes. 2018;9(5):422-436. doi: 10.1080/19490976.2018.1460014. Epub 2018 Jul 19.

2.

Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice.

Ma EL, Smith AD, Desai N, Cheung L, Hanscom M, Stoica BA, Loane DJ, Shea-Donohue T, Faden AI.

Brain Behav Immun. 2017 Nov;66:56-69. doi: 10.1016/j.bbi.2017.06.018. Epub 2017 Jul 1.

3.

Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.

Buzza MS, Johnson TA, Conway GD, Martin EW, Mukhopadhyay S, Shea-Donohue T, Antalis TM.

J Biol Chem. 2017 Jun 30;292(26):10801-10812. doi: 10.1074/jbc.M116.771469. Epub 2017 May 10.

4.

Parasites, nutrition, immune responses and biology of metabolic tissues.

Shea-Donohue T, Qin B, Smith A.

Parasite Immunol. 2017 May;39(5). doi: 10.1111/pim.12422. Epub 2017 Mar 22. Review.

5.

Development of A Novel Murine Model of Combined Radiation and Peripheral Tissue Trauma Injuries.

Antonic V, Jackson IL, Ganga G, Shea-Donohue T, Vujaskovic Z.

Radiat Res. 2017 Feb;187(2):241-250. doi: 10.1667/RR14557.1. Epub 2017 Jan 24.

6.

Neuroimmune Modulation of Gut Function.

Shea-Donohue T, Urban JF Jr.

Handb Exp Pharmacol. 2017;239:247-267. doi: 10.1007/164_2016_109. Review.

PMID:
28035531
7.

The synthesis of OspD3 (ShET2) in Shigella flexneri is independent of OspC1.

Faherty CS, Wu T, Morris CR, Grassel CL, Rasko DA, Harper JM, Shea-Donohue T, Fasano A, Barry EM.

Gut Microbes. 2016 Nov;7(6):486-502. Epub 2016 Sep 22.

8.

Critical Role for Interleukin-25 in Host Protective Th2 Memory Response against Heligmosomoides polygyrus bakeri.

Pei C, Zhao C, Wang AJ, Fan AX, Grinchuk V, Smith A, Sun R, Xie Y, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A, Yang Z.

Infect Immun. 2016 Nov 18;84(12):3328-3337. Print 2016 Dec.

9.

Mechanisms Involved in the Development of the Chronic Gastrointestinal Syndrome in Nonhuman Primates after Total-Body Irradiation with Bone Marrow Shielding.

Shea-Donohue T, Fasano A, Zhao A, Notari L, Yan S, Sun R, Bohl JA, Desai N, Tudor G, Morimoto M, Booth C, Bennett A, Farese AM, MacVittie TJ.

Radiat Res. 2016 Jun;185(6):591-603. doi: 10.1667/RR14024.1. Epub 2016 May 25.

10.

Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines.

McLean LP, Smith A, Cheung L, Urban JF Jr, Sun R, Grinchuk V, Desai N, Zhao A, Raufman JP, Shea-Donohue T.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G130-41. doi: 10.1152/ajpgi.00461.2014. Epub 2016 May 12.

11.

Fundamentals of Neurogastroenterology: Basic Science.

Vanner S, Greenwood-Van Meerveld B, Mawe G, Shea-Donohue T, Verdu EF, Wood J, Grundy D.

Gastroenterology. 2016 Feb 18. pii: S0016-5085(16)00184-0. doi: 10.1053/j.gastro.2016.02.018. [Epub ahead of print]

12.

Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance.

Sun R, Urban JF Jr, Notari L, Vanuytsel T, Madden KB, Bohl JA, Ramalingam TR, Wynn TA, Zhao A, Shea-Donohue T.

Infect Immun. 2016 Mar 24;84(4):1032-1044. doi: 10.1128/IAI.00990-15. Print 2016 Apr.

13.

Erratum to: Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis.

Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Pei C, Ma B, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A.

Microbiome. 2015 Dec 21;3:77. doi: 10.1186/s40168-015-0142-1. No abstract available.

14.

IL-25 or IL-17E Protects against High-Fat Diet-Induced Hepatic Steatosis in Mice Dependent upon IL-13 Activation of STAT6.

Wang AJ, Yang Z, Grinchuk V, Smith A, Qin B, Lu N, Wang D, Wang H, Ramalingam TR, Wynn TA, Urban JF Jr, Shea-Donohue T, Zhao A.

J Immunol. 2015 Nov 15;195(10):4771-80. doi: 10.4049/jimmunol.1500337. Epub 2015 Sep 30.

15.

Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis.

Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Mongodin E, Pei C, Ma B, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A.

Microbiome. 2015 Sep 17;3:40. doi: 10.1186/s40168-015-0103-8. Erratum in: Microbiome. 2015;3:77. Mongodin, Emmanuel [Added].

16.

Enteric nematodes and the path to up-regulation of type 2 cytokines IL-4 and IL-13.

Shea-Donohue T, Sun R, Bohl JA, McLean LP, Zhao A.

Cytokine. 2015 Sep;75(1):62-7. doi: 10.1016/j.cyto.2015.06.007. Epub 2015 Jul 15. Review.

PMID:
26188364
17.

Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium.

McLean LP, Smith A, Cheung L, Sun R, Grinchuk V, Vanuytsel T, Desai N, Urban JF Jr, Zhao A, Raufman JP, Shea-Donohue T.

Inflamm Bowel Dis. 2015 Aug;21(8):1860-71. doi: 10.1097/MIB.0000000000000408.

18.

Changes in Epithelial Barrier Function in Response to Parasitic Infection: Implications for IBD Pathogenesis.

Fernández-Blanco JA, Estévez J, Shea-Donohue T, Martínez V, Vergara P.

J Crohns Colitis. 2015 Jun;9(6):463-76. doi: 10.1093/ecco-jcc/jjv056. Epub 2015 Mar 28.

19.

An unsuspected cause of diarrhoea and gastrointestinal bleeding during corticosteroid therapy.

Vanuytsel T, Sagaert X, Van Dijck H, Vandepitte K, Shea-Donohue T, Tack J, Van den Brande P.

Acta Gastroenterol Belg. 2014 Jun;77(2):259-61.

PMID:
25090826
20.

SerpinB2 mediated regulation of macrophage function during enteric infection.

Shea-Donohue T, Zhao A, Antalis TM.

Gut Microbes. 2014 Mar-Apr;5(2):254-8. doi: 10.4161/gmic.28093. Epub 2014 Feb 5.

21.

Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection.

Notari L, Riera DC, Sun R, Bohl JA, McLean LP, Madden KB, van Rooijen N, Vanuytsel T, Urban JF Jr, Zhao A, Shea-Donohue T.

PLoS One. 2014 Jan 23;9(1):e84763. doi: 10.1371/journal.pone.0084763. eCollection 2014.

22.

Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice.

Wang AJ, Smith A, Li Y, Urban JF Jr, Ramalingam TR, Wynn TA, Lu N, Shea-Donohue T, Yang Z, Zhao A.

Cell Biosci. 2014 Nov 26;4:72. doi: 10.1186/2045-3701-4-72. eCollection 2014.

23.

Combined blockade of IL-17A and IL-17F may prevent the development of experimental colitis.

McLean LP, Cross RK, Shea-Donohue T.

Immunotherapy. 2013 Sep;5(9):923-5. doi: 10.2217/imt.13.87.

24.

Selenium status alters the immune response and expulsion of adult Heligmosomoides bakeri worms in mice.

Smith AD, Cheung L, Beshah E, Shea-Donohue T, Urban JF Jr.

Infect Immun. 2013 Jul;81(7):2546-53. doi: 10.1128/IAI.01047-12. Epub 2013 May 6.

25.

SerpinB2 is critical to Th2 immunity against enteric nematode infection.

Zhao A, Yang Z, Sun R, Grinchuk V, Netzel-Arnett S, Anglin IE, Driesbaugh KH, Notari L, Bohl JA, Madden KB, Urban JF Jr, Antalis TM, Shea-Donohue T.

J Immunol. 2013 Jun 1;190(11):5779-87. doi: 10.4049/jimmunol.1200293. Epub 2013 Apr 29.

26.

Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity.

Yang Z, Grinchuk V, Urban JF Jr, Bohl J, Sun R, Notari L, Yan S, Ramalingam T, Keegan AD, Wynn TA, Shea-Donohue T, Zhao A.

PLoS One. 2013;8(3):e59441. doi: 10.1371/journal.pone.0059441. Epub 2013 Mar 25.

27.

Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity.

Yang Z, Grinchuk V, Smith A, Qin B, Bohl JA, Sun R, Notari L, Zhang Z, Sesaki H, Urban JF Jr, Shea-Donohue T, Zhao A.

Infect Immun. 2013 Jun;81(6):1905-14. doi: 10.1128/IAI.00053-13. Epub 2013 Mar 18.

28.

Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice.

Ramesh D, Gamage TF, Vanuytsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH.

Neuropsychopharmacology. 2013 May;38(6):1039-49. doi: 10.1038/npp.2012.269. Epub 2013 Jan 3.

29.

IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent.

Yang Z, Sun R, Grinchuk V, Fernández-Blanco JA, Notari L, Bohl JA, McLean LP, Ramalingam TR, Wynn TA, Urban JF Jr, Vogel SN, Shea-Donohue T, Zhao A.

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G381-9. doi: 10.1152/ajpgi.00357.2012. Epub 2012 Dec 20. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15;304(12):G1137. Blanco, Joan Antoni Fernandez [corrected to Fernández-Blanco, Joan Antoni].

30.

Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo.

Faherty CS, Harper JM, Shea-Donohue T, Barry EM, Kaper JB, Fasano A, Nataro JP.

PLoS One. 2012;7(11):e49980. doi: 10.1371/journal.pone.0049980. Epub 2012 Nov 16. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/44400281-2456-4853-a89b-4dea4f9aa27b. Faherty, Christina [corrected to Faherty, Christina S].

31.

Evidence of delayed gastrointestinal syndrome in high-dose irradiated mice.

Booth C, Tudor G, Tonge N, Shea-Donohue T, MacVittie TJ.

Health Phys. 2012 Oct;103(4):400-10.

32.

Vedolizumab for the treatment of ulcerative colitis and Crohn's disease.

McLean LP, Shea-Donohue T, Cross RK.

Immunotherapy. 2012 Sep;4(9):883-98. doi: 10.2217/imt.12.85. Review.

33.

The prolonged gastrointestinal syndrome in rhesus macaques: the relationship between gastrointestinal, hematopoietic, and delayed multi-organ sequelae following acute, potentially lethal, partial-body irradiation.

MacVittie TJ, Bennett A, Booth C, Garofalo M, Tudor G, Ward A, Shea-Donohue T, Gelfond D, McFarland E, Jackson W 3rd, Lu W, Farese AM.

Health Phys. 2012 Oct;103(4):427-53. doi: 10.1097/HP.0b013e318266eb4c.

34.

The acute gastrointestinal subsyndrome of the acute radiation syndrome: a rhesus macaque model.

MacVittie TJ, Farese AM, Bennett A, Gelfond D, Shea-Donohue T, Tudor G, Booth C, McFarland E, Jackson W 3rd.

Health Phys. 2012 Oct;103(4):411-26. doi: 10.1097/HP.0b013e31826525f0.

PMID:
22929470
35.

Major signaling pathways in intestinal stem cells.

Vanuytsel T, Senger S, Fasano A, Shea-Donohue T.

Biochim Biophys Acta. 2013 Feb;1830(2):2410-26. doi: 10.1016/j.bbagen.2012.08.006. Epub 2012 Aug 16. Review.

36.

Mechanisms of smooth muscle responses to inflammation.

Shea-Donohue T, Notari L, Sun R, Zhao A.

Neurogastroenterol Motil. 2012 Sep;24(9):802-11. doi: 10.1111/j.1365-2982.2012.01986.x. Review.

37.

Regulation of inflammation by interleukin-4: a review of "alternatives".

Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP.

J Leukoc Biol. 2012 Oct;92(4):753-64. doi: 10.1189/jlb.0412214. Epub 2012 Jul 10. Review.

38.

Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vitro and In Vivo.

Yang Z, Grinchuk V, Ip SP, Che CT, Fong HH, Lao L, Wu JC, Sung JJ, Berman B, Shea-Donohue T, Zhao A.

Evid Based Complement Alternat Med. 2012;2012:491496. doi: 10.1155/2012/491496. Epub 2012 Feb 22.

39.

Matriptase protects against experimental colitis and promotes intestinal barrier recovery.

Netzel-Arnett S, Buzza MS, Shea-Donohue T, Désilets A, Leduc R, Fasano A, Bugge TH, Antalis TM.

Inflamm Bowel Dis. 2012 Jul;18(7):1303-14. doi: 10.1002/ibd.21930. Epub 2011 Nov 13.

40.

Enteric pathogens and gut function: Role of cytokines and STATs.

Shea-Donohue T, Fasano A, Smith A, Zhao A.

Gut Microbes. 2010 Sep;1(5):316-324. Epub 2010 May 12.

41.

The pathogenicity of an enteric Citrobacter rodentium Infection is enhanced by deficiencies in the antioxidants selenium and vitamin E.

Smith AD, Botero S, Shea-Donohue T, Urban JF Jr.

Infect Immun. 2011 Apr;79(4):1471-8. doi: 10.1128/IAI.01017-10. Epub 2011 Jan 18.

42.

Critical role of IL-25 in nematode infection-induced alterations in intestinal function.

Zhao A, Urban JF Jr, Sun R, Stiltz J, Morimoto M, Notari L, Madden KB, Yang Z, Grinchuk V, Ramalingam TR, Wynn TA, Shea-Donohue T.

J Immunol. 2010 Dec 1;185(11):6921-9. doi: 10.4049/jimmunol.1000450. Epub 2010 Oct 25.

43.

Sphingosine-1-phosphate regulates the expression of adherens junction protein E-cadherin and enhances intestinal epithelial cell barrier function.

Greenspon J, Li R, Xiao L, Rao JN, Sun R, Strauch ED, Shea-Donohue T, Wang JY, Turner DJ.

Dig Dis Sci. 2011 May;56(5):1342-53. doi: 10.1007/s10620-010-1421-0. Epub 2010 Oct 9.

44.

Mast cells.

Shea-Donohue T, Stiltz J, Zhao A, Notari L.

Curr Gastroenterol Rep. 2010 Oct;12(5):349-57. doi: 10.1007/s11894-010-0132-1. Review.

45.

Role of enteric nerves in immune-mediated changes in protease-activated receptor 2 effects on gut function.

Shea-Donohue T, Notari L, Stiltz J, Sun R, Madden KB, Urban JF Jr, Zhao A.

Neurogastroenterol Motil. 2010 Oct;22(10):1138-e291. doi: 10.1111/j.1365-2982.2010.01557.x. Epub 2010 Jul 11.

46.

CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice.

Choi KM, Kashyap PC, Dutta N, Stoltz GJ, Ordog T, Shea Donohue T, Bauer AJ, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G.

Gastroenterology. 2010 Jun;138(7):2399-409, 2409.e1. doi: 10.1053/j.gastro.2010.02.014. Epub 2010 Feb 20.

47.

Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.

Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4200-5. doi: 10.1073/pnas.0903923107. Epub 2010 Feb 8.

48.

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2.

Tripathi A, Lammers KM, Goldblum S, Shea-Donohue T, Netzel-Arnett S, Buzza MS, Antalis TM, Vogel SN, Zhao A, Yang S, Arrietta MC, Meddings JB, Fasano A.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16799-804. doi: 10.1073/pnas.0906773106. Epub 2009 Sep 15.

49.

IL-13 receptor alpha2 regulates the immune and functional response to Nippostrongylus brasiliensis infection.

Morimoto M, Zhao A, Sun R, Stiltz J, Madden KB, Mentink-Kane M, Ramalingam T, Wynn TA, Urban JF Jr, Shea-Donohue T.

J Immunol. 2009 Aug 1;183(3):1934-9. doi: 10.4049/jimmunol.0804299. Epub 2009 Jul 8.

50.

Mice deficient in the CXCR2 ligand, CXCL1 (KC/GRO-alpha), exhibit increased susceptibility to dextran sodium sulfate (DSS)-induced colitis.

Shea-Donohue T, Thomas K, Cody MJ, Aiping Zhao, Detolla LJ, Kopydlowski KM, Fukata M, Lira SA, Vogel SN.

Innate Immun. 2008 Apr;14(2):117-24. doi: 10.1177/1753425908088724.

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