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Items: 17


ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK.

J Exp Med. 2019 Oct 3. pii: jem.20180610. doi: 10.1084/jem.20180610. [Epub ahead of print]


Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses.

Shaw TN, Inkson CA, Villegas-Mendez A, Pattinson DJ, Strangward P, Else KJ, Draper SJ, Zeef LAH, Couper KN.

Front Immunol. 2019 Feb 19;10:248. doi: 10.3389/fimmu.2019.00248. eCollection 2019.


Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression.

Shaw TN, Houston SA, Wemyss K, Bridgeman HM, Barbera TA, Zangerle-Murray T, Strangward P, Ridley AJL, Wang P, Tamoutounour S, Allen JE, Konkel JE, Grainger JR.

J Exp Med. 2018 Jun 4;215(6):1507-1518. doi: 10.1084/jem.20180019. Epub 2018 May 22.


Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments.

Villegas-Mendez A, Strangward P, Shaw TN, Rajkovic I, Tosevski V, Forman R, Muller W, Couper KN.

Infect Immun. 2017 Oct 18;85(11). pii: e01035-16. doi: 10.1128/IAI.01035-16. Print 2017 Nov.


Macrophages in gastrointestinal homeostasis and inflammation.

Grainger JR, Konkel JE, Zangerle-Murray T, Shaw TN.

Pflugers Arch. 2017 Apr;469(3-4):527-539. doi: 10.1007/s00424-017-1958-2. Epub 2017 Mar 10. Review.


A quantitative brain map of experimental cerebral malaria pathology.

Strangward P, Haley MJ, Shaw TN, Schwartz JM, Greig R, Mironov A, de Souza JB, Cruickshank SM, Craig AG, Milner DA Jr, Allan SM, Couper KN.

PLoS Pathog. 2017 Mar 8;13(3):e1006267. doi: 10.1371/journal.ppat.1006267. eCollection 2017 Mar.


Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

Shaw TN, Stewart-Hutchinson PJ, Strangward P, Dandamudi DB, Coles JA, Villegas-Mendez A, Gallego-Delgado J, van Rooijen N, Zindy E, Rodriguez A, Brewer JM, Couper KN, Dustin ML.

PLoS Pathog. 2015 Nov 12;11(11):e1005210. doi: 10.1371/journal.ppat.1005210. eCollection 2015.


Parasite-Specific CD4+ IFN-γ+ IL-10+ T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection.

Villegas-Mendez A, Shaw TN, Inkson CA, Strangward P, de Souza JB, Couper KN.

Infect Immun. 2015 Oct 12;84(1):34-46. doi: 10.1128/IAI.01100-15. Print 2016 Jan.


IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.

Besnard AG, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw TN, Couper KN, Ryffel B, Liew FY.

PLoS Pathog. 2015 Feb 6;11(2):e1004607. doi: 10.1371/journal.ppat.1004607. eCollection 2015 Feb.


The subcellular location of ovalbumin in Plasmodium berghei blood stages influences the magnitude of T-cell responses.

Lin JW, Shaw TN, Annoura T, Fougère A, Bouchier P, Chevalley-Maurel S, Kroeze H, Franke-Fayard B, Janse CJ, Couper KN, Khan SM.

Infect Immun. 2014 Nov;82(11):4654-65. doi: 10.1128/IAI.01940-14. Epub 2014 Aug 25.


IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.

Villegas-Mendez A, de Souza JB, Lavelle SW, Gwyer Findlay E, Shaw TN, van Rooijen N, Saris CJ, Hunter CA, Riley EM, Couper KN.

PLoS Pathog. 2013;9(4):e1003293. doi: 10.1371/journal.ppat.1003293. Epub 2013 Apr 11.


IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.

Gwyer Findlay E, Villegas-Mendez A, de Souza JB, Inkson CA, Shaw TN, Saris CJ, Hunter CA, Riley EM, Couper KN.

J Immunol. 2013 May 1;190(9):4553-61. doi: 10.4049/jimmunol.1202916. Epub 2013 Mar 27.


IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, Hafalla JC, Blount DG, Hunter CA, Riley EM, Couper KN.

J Immunol. 2012 Jul 15;189(2):968-79. doi: 10.4049/jimmunol.1200688. Epub 2012 Jun 20.


Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

Villegas-Mendez A, de Souza JB, Murungi L, Hafalla JC, Shaw TN, Greig R, Riley EM, Couper KN.

J Immunol. 2011 Sep 15;187(6):2885-97. doi: 10.4049/jimmunol.1100241. Epub 2011 Aug 31.


Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.

Duffy KJ, Darcy MG, Delorme E, Dillon SB, Eppley DF, Erickson-Miller C, Giampa L, Hopson CB, Huang Y, Keenan RM, Lamb P, Leong L, Liu N, Miller SG, Price AT, Rosen J, Shah R, Shaw TN, Smith H, Stark KC, Tian SS, Tyree C, Wiggall KJ, Zhang L, Luengo JI.

J Med Chem. 2001 Oct 25;44(22):3730-45.


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