Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 73

1.

Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery.

Demers DH, Knestrick MA, Fleeman R, Tawfik R, Azhari A, Souza A, Vesely B, Netherton M, Gupta R, Colon BL, Rice CA, Rodríguez-Pérez MA, Rohde KH, Kyle DE, Shaw LN, Baker BJ.

Mar Drugs. 2018 Oct 10;16(10). pii: E376. doi: 10.3390/md16100376.

2.

Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens.

Fleeman RM, Debevec G, Antonen K, Adams JL, Santos RG, Welmaker GS, Houghten RA, Giulianotti MA, Shaw LN.

Front Microbiol. 2018 Jun 14;9:1301. doi: 10.3389/fmicb.2018.01301. eCollection 2018.

3.

Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine β-Lactamases.

Pemberton OA, Zhang X, Nichols DA, DeFrees K, Jaishankar P, Bonnet R, Adams J, Shaw LN, Renslo AR, Chen Y.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02563-17. doi: 10.1128/AAC.02563-17. Print 2018 Aug.

PMID:
29844038
4.

Identification of a unique transcriptional architecture for the sigS operon in Staphylococcus aureus.

Miller HK, Burda WN, Carroll RK, Shaw LN.

FEMS Microbiol Lett. 2018 Jun 1;365(12). doi: 10.1093/femsle/fny108.

PMID:
29688345
5.

Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates Targeting Mycobacterium tuberculosis and Mycobacterium abscessus.

Gupta R, Rodrigues Felix C, Akerman MP, Akerman KJ, Slabber CA, Wang W, Adams J, Shaw LN, Tse-Dinh YC, Munro OQ, Rohde KH.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01696-17. doi: 10.1128/AAC.01696-17. Print 2018 May.

6.

Towards the complete proteinaceous regulome of Acinetobacter baumannii.

Casella LG, Weiss A, Pérez-Rueda E, Ibarra JA, Shaw LN.

Microb Genom. 2017 Mar 23;3(3):mgen000107. doi: 10.1099/mgen.0.000107. eCollection 2017 Mar.

7.

Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus.

Elmwall J, Kwiecinski J, Na M, Ali AA, Osla V, Shaw LN, Wang W, Sävman K, Josefsson E, Bylund J, Jin T, Welin A, Karlsson A.

Infect Immun. 2017 Jun 20;85(7). pii: e00177-17. doi: 10.1128/IAI.00177-17. Print 2017 Jul.

8.

Complete Eradication of Biofilm From Orthopedic Materials.

Leary JT, Werger MM, Broach WH, Shaw LN, Santoni BG, Bernasek TL, Lyons ST.

J Arthroplasty. 2017 Aug;32(8):2513-2518. doi: 10.1016/j.arth.2017.03.050. Epub 2017 Mar 29.

PMID:
28434696
9.

Staphylococcus aureus nitric oxide synthase (saNOS) modulates aerobic respiratory metabolism and cell physiology.

Mogen AB, Carroll RK, James KL, Lima G, Silva D, Culver JA, Petucci C, Shaw LN, Rice KC.

Mol Microbiol. 2017 Jul;105(1):139-157. doi: 10.1111/mmi.13693. Epub 2017 May 10.

10.

Transcriptomic analysis of staphylococcal sRNAs: insights into species-specific adaption and the evolution of pathogenesis.

Broach WH, Weiss A, Shaw LN.

Microb Genom. 2016 Jul 26;2(7):e000065. doi: 10.1099/mgen.0.000065. eCollection 2016 Jul.

11.

Towards the complete small RNome of Acinetobacter baumannii.

Weiss A, Broach WH, Lee MC, Shaw LN.

Microb Genom. 2016 Mar 2;2(3):e000045. doi: 10.1099/mgen.0.000045. eCollection 2016 Mar.

12.

Characterizing the Antimicrobial Activity of N2,N4-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii.

Fleeman R, Van Horn KS, Barber MM, Burda WN, Flanigan DL, Manetsch R, Shaw LN.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00059-17. doi: 10.1128/AAC.00059-17. Print 2017 Jun.

13.

The "PepSAVI-MS" Pipeline for Natural Product Bioactive Peptide Discovery.

Kirkpatrick CL, Broberg CA, McCool EN, Lee WJ, Chao A, McConnell EW, Pritchard DA, Hebert M, Fleeman R, Adams J, Jamil A, Madera L, Strömstedt AA, Göransson U, Liu Y, Hoskin DW, Shaw LN, Hicks LM.

Anal Chem. 2017 Jan 17;89(2):1194-1201. doi: 10.1021/acs.analchem.6b03625. Epub 2017 Jan 4.

PMID:
27991763
14.

Exposing the Unique Connection between Metabolism and Virulence in Staphylococcus aureus.

Weiss A, Fleeman RM, Shaw LN.

Cell Chem Biol. 2016 Nov 17;23(11):1317-1319. doi: 10.1016/j.chembiol.2016.11.003.

15.

The ω Subunit Governs RNA Polymerase Stability and Transcriptional Specificity in Staphylococcus aureus.

Weiss A, Moore BD, Tremblay MH, Chaput D, Kremer A, Shaw LN.

J Bacteriol. 2016 Dec 28;199(2). pii: e00459-16. doi: 10.1128/JB.00459-16. Print 2017 Jan 15.

16.

An Intracellular Peptidyl-Prolyl cis/trans Isomerase Is Required for Folding and Activity of the Staphylococcus aureus Secreted Virulence Factor Nuclease.

Wiemels RE, Cech SM, Meyer NM, Burke CA, Weiss A, Parks AR, Shaw LN, Carroll RK.

J Bacteriol. 2016 Dec 13;199(1). pii: e00453-16. Print 2017 Jan 1.

17.

A family of genus-specific RNAs in tandem with DNA-binding proteins control expression of the badA major virulence factor gene in Bartonella henselae.

Tu N, Carroll RK, Weiss A, Shaw LN, Nicolas G, Thomas S, Lima A, Okaro U, Anderson B.

Microbiologyopen. 2017 Apr;6(2). doi: 10.1002/mbo3.420. Epub 2016 Oct 28.

18.

Staphylococcus aureus SufT: an essential iron-sulphur cluster assembly factor in cells experiencing a high-demand for lipoic acid.

Mashruwala AA, Roberts CA, Bhatt S, May KL, Carroll RK, Shaw LN, Boyd JM.

Mol Microbiol. 2016 Dec;102(6):1099-1119. doi: 10.1111/mmi.13539. Epub 2016 Oct 21.

19.

Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc.

Balasubramanian D, Ohneck EA, Chapman J, Weiss A, Kim MK, Reyes-Robles T, Zhong J, Shaw LN, Lun DS, Ueberheide B, Shopsin B, Torres VJ.

MBio. 2016 Jun 21;7(3). pii: e00818-16. doi: 10.1128/mBio.00818-16.

20.

Regulatory Requirements for Staphylococcus aureus Nitric Oxide Resistance.

Grosser MR, Weiss A, Shaw LN, Richardson AR.

J Bacteriol. 2016 Jul 13;198(15):2043-55. doi: 10.1128/JB.00229-16. Print 2016 Aug 1.

21.

Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa.

von Salm JL, Witowski CG, Fleeman RM, McClintock JB, Amsler CD, Shaw LN, Baker BJ.

Org Lett. 2016 Jun 3;18(11):2596-9. doi: 10.1021/acs.orglett.6b00979. Epub 2016 May 13.

22.

Characterizing the transcriptional adaptation of Staphylococcus aureus to stationary phase growth.

Weiss A, Broach WH, Shaw LN.

Pathog Dis. 2016 Jul;74(5). pii: ftw046. doi: 10.1093/femspd/ftw046. Epub 2016 May 8.

23.

Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus.

Carroll RK, Weiss A, Broach WH, Wiemels RE, Mogen AB, Rice KC, Shaw LN.

MBio. 2016 Feb 9;7(1):e01990-15. doi: 10.1128/mBio.01990-15.

24.

Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities.

Bionda N, Fleeman RM, de la Fuente-Núñez C, Rodriguez MC, Reffuveille F, Shaw LN, Pastar I, Davis SC, Hancock REW, Cudic P.

Eur J Med Chem. 2016 Jan 27;108:354-363. doi: 10.1016/j.ejmech.2015.11.032. Epub 2015 Nov 30.

25.

Global Regulator of Virulence A (GrvA) Coordinates Expression of Discrete Pathogenic Mechanisms in Enterohemorrhagic Escherichia coli through Interactions with GadW-GadE.

Morgan JK, Carroll RK, Harro CM, Vendura KW, Shaw LN, Riordan JT.

J Bacteriol. 2015 Nov 2;198(3):394-409. doi: 10.1128/JB.00556-15. Print 2016 Feb 1.

26.

Confirming Sterility of an Autoclaved Infected Femoral Component for Use in an Articulated Antibiotic Knee Spacer: A Pilot Study.

Lyons ST, Wright CA, Krute CN, Rivera FE, Carroll RK, Shaw LN.

J Arthroplasty. 2016 Jan;31(1):245-9. doi: 10.1016/j.arth.2015.06.068. Epub 2015 Jul 11.

PMID:
26282497
27.

Small things considered: the small accessory subunits of RNA polymerase in Gram-positive bacteria.

Weiss A, Shaw LN.

FEMS Microbiol Rev. 2015 Jul;39(4):541-54. doi: 10.1093/femsre/fuv005. Epub 2015 Apr 14. Review.

28.

Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens.

Fleeman R, LaVoi TM, Santos RG, Morales A, Nefzi A, Welmaker GS, Medina-Franco JL, Giulianotti MA, Houghten RA, Shaw LN.

J Med Chem. 2015 Apr 23;58(8):3340-55. doi: 10.1021/jm501628s. Epub 2015 Apr 1.

PMID:
25780985
29.

The membrane protein PrsS mimics σS in protecting Staphylococcus aureus against cell wall-targeting antibiotics and DNA-damaging agents.

Krute CN, Bell-Temin H, Miller HK, Rivera FE, Weiss A, Stevens SM, Shaw LN.

Microbiology. 2015 May;161(Pt 5):1136-48. doi: 10.1099/mic.0.000065. Epub 2015 Mar 4.

30.

RNA-Sequencing of Staphylococcus aureus Messenger RNA.

Carroll RK, Weiss A, Shaw LN.

Methods Mol Biol. 2016;1373:131-41. doi: 10.1007/7651_2014_192.

PMID:
25646612
31.

The disruption of prenylation leads to pleiotropic rearrangements in cellular behavior in Staphylococcus aureus.

Krute CN, Carroll RK, Rivera FE, Weiss A, Young RM, Shilling A, Botlani M, Varma S, Baker BJ, Shaw LN.

Mol Microbiol. 2015 Mar;95(5):819-32. doi: 10.1111/mmi.12900. Epub 2015 Jan 16.

32.

Investigating the genetic regulation of the ECF sigma factor σS in Staphylococcus aureus.

Burda WN, Miller HK, Krute CN, Leighton SL, Carroll RK, Shaw LN.

BMC Microbiol. 2014 Nov 30;14:280. doi: 10.1186/s12866-014-0280-9.

33.

The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages.

Koziel J, Chmiest D, Bryzek D, Kmiecik K, Mizgalska D, Maciag-Gudowska A, Shaw LN, Potempa J.

J Innate Immun. 2015;7(2):187-98. doi: 10.1159/000368048. Epub 2014 Oct 30.

34.

Contribution of the nos-pdt operon to virulence phenotypes in methicillin-sensitive Staphylococcus aureus.

Sapp AM, Mogen AB, Almand EA, Rivera FE, Shaw LN, Richardson AR, Rice KC.

PLoS One. 2014 Oct 2;9(9):e108868. doi: 10.1371/journal.pone.0108868. eCollection 2014.

35.
36.

The lone S41 family C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and contributes to virulence.

Carroll RK, Rivera FE, Cavaco CK, Johnson GM, Martin D, Shaw LN.

Microbiology. 2014 Aug;160(Pt 8):1737-48. doi: 10.1099/mic.0.079798-0. Epub 2014 Jun 13.

37.

Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines.

Van Horn KS, Burda WN, Fleeman R, Shaw LN, Manetsch R.

J Med Chem. 2014 Apr 10;57(7):3075-93. doi: 10.1021/jm500039e. Epub 2014 Mar 31.

PMID:
24625106
38.

The δ subunit of RNA polymerase guides promoter selectivity and virulence in Staphylococcus aureus.

Weiss A, Ibarra JA, Paoletti J, Carroll RK, Shaw LN.

Infect Immun. 2014 Apr;82(4):1424-35. doi: 10.1128/IAI.01508-14. Epub 2014 Feb 3.

39.

Mannitol utilisation is required for protection of Staphylococcus aureus from human skin antimicrobial fatty acids.

Kenny JG, Moran J, Kolar SL, Ulanov A, Li Z, Shaw LN, Josefsson E, Horsburgh MJ.

PLoS One. 2013 Jul 4;8(7):e67698. doi: 10.1371/journal.pone.0067698. Print 2013.

40.

Draft Genome Sequence of Strain CBD-635, a Methicillin-Resistant Staphylococcus aureus USA100 Isolate.

Carroll RK, Burda WN, Roberts JC, Peak KK, Cannons AC, Shaw LN.

Genome Announc. 2013 Jul 11;1(4). pii: e00491-13. doi: 10.1128/genomeA.00491-13.

41.

Staphylococcal proteases aid in evasion of the human complement system.

Jusko M, Potempa J, Kantyka T, Bielecka E, Miller HK, Kalinska M, Dubin G, Garred P, Shaw LN, Blom AM.

J Innate Immun. 2014;6(1):31-46. doi: 10.1159/000351458. Epub 2013 Jul 3.

42.

Staphopains modulate Staphylococcus aureus biofilm integrity.

Mootz JM, Malone CL, Shaw LN, Horswill AR.

Infect Immun. 2013 Sep;81(9):3227-38. doi: 10.1128/IAI.00377-13. Epub 2013 Jun 24.

43.

Effect of ester to amide or N-methylamide substitution on bacterial membrane depolarization and antibacterial activity of novel cyclic lipopeptides.

Bionda N, Fleeman RM, Shaw LN, Cudic P.

ChemMedChem. 2013 Aug;8(8):1394-402. doi: 10.1002/cmdc.201300173. Epub 2013 Jun 18.

44.

Global analysis of transcriptional regulators in Staphylococcus aureus.

Ibarra JA, Pérez-Rueda E, Carroll RK, Shaw LN.

BMC Genomics. 2013 Feb 26;14:126. doi: 10.1186/1471-2164-14-126.

45.

The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine.

Carroll RK, Veillard F, Gagne DT, Lindenmuth JM, Poreba M, Drag M, Potempa J, Shaw LN.

Biol Chem. 2013 Jun;394(6):791-803. doi: 10.1515/hsz-2012-0308.

46.

Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability.

Kolar SL, Ibarra JA, Rivera FE, Mootz JM, Davenport JE, Stevens SM, Horswill AR, Shaw LN.

Microbiologyopen. 2013 Feb;2(1):18-34. doi: 10.1002/mbo3.55. Epub 2012 Dec 11.

47.

Studies on the antimicrobial properties of N-acylated ciprofloxacins.

Cormier R, Burda WN, Harrington L, Edlinger J, Kodigepalli KM, Thomas J, Kapolka R, Roma G, Anderson BE, Turos E, Shaw LN.

Bioorg Med Chem Lett. 2012 Oct 15;22(20):6513-20. doi: 10.1016/j.bmcl.2012.05.026. Epub 2012 Jul 1.

48.

Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.

Beau J, Mahid N, Burda WN, Harrington L, Shaw LN, Mutka T, Kyle DE, Barisic B, van Olphen A, Baker BJ.

Mar Drugs. 2012 Apr;10(4):762-74. doi: 10.3390/md10040762. Epub 2012 Mar 28.

49.

The extracytoplasmic function sigma factor σS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus.

Miller HK, Carroll RK, Burda WN, Krute CN, Davenport JE, Shaw LN.

J Bacteriol. 2012 Aug;194(16):4342-54. doi: 10.1128/JB.00484-12. Epub 2012 Jun 8.

50.

Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus.

Carroll RK, Robison TM, Rivera FE, Davenport JE, Jonsson IM, Florczyk D, Tarkowski A, Potempa J, Koziel J, Shaw LN.

Microbes Infect. 2012 Sep;14(11):989-99. doi: 10.1016/j.micinf.2012.04.013. Epub 2012 May 2.

Supplemental Content

Loading ...
Support Center