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A population-based case-control study of the association between weather-related extreme heat events and orofacial clefts.

Soim A, Sheridan SC, Hwang SA, Hsu WH, Fisher SC, Shaw GM, Feldkamp ML, Romitti PA, Reefhuis J, Langlois PH, Browne ML, Lin S; National Birth Defects Prevention Study.

Birth Defects Res. 2018 Oct 19:e1385. doi: 10.1002/bdr2.1385. [Epub ahead of print]


A virtual patient model for mechanical ventilation.

Morton SE, Dickson J, Chase JG, Docherty P, Desaive T, Howe SL, Shaw GM, Tawhai M.

Comput Methods Programs Biomed. 2018 Oct;165:77-87. doi: 10.1016/j.cmpb.2018.08.004. Epub 2018 Aug 10.


Congenital heart disease complexity and childhood cancer risk.

Collins RT 2nd, Von Behren J, Yang W, Carmichael SL, Reynolds P, Fisher PG, Shaw GM.

Birth Defects Res. 2018 Oct 16. doi: 10.1002/bdr2.1390. [Epub ahead of print]


An application of data mining to identify potential risk factors for anophthalmia and microphthalmia.

Weber KA, Yang W, Carmichael SL, Lupo PJ, Dukhovny S, Yazdy MM, Lin AE, Van Bennekom CM, Mitchell AA, Shaw GM; National Birth Defects Prevention Study.

Paediatr Perinat Epidemiol. 2018 Oct 9. doi: 10.1111/ppe.12509. [Epub ahead of print]


The Authors Respond.

Francis SS, Shaw GM.

Epidemiology. 2018 Oct 1. doi: 10.1097/EDE.0000000000000935. [Epub ahead of print] No abstract available.


Copy number variants in hypoplastic right heart syndrome.

Giannakou A, Sicko RJ, Kay DM, Zhang W, Romitti PA, Caggana M, Shaw GM, Jelliffe-Pawlowski LL, Mills JL.

Am J Med Genet A. 2018 Oct 5. doi: 10.1002/ajmg.a.40527. [Epub ahead of print]


Dominant negative GPR161 rare variants are risk factors of human spina bifida.

Kim SE, Lei Y, Hwang SH, Wlodarczyk BJ, Mukhopadhyay S, Shaw GM, Elizabeth Ross M, Finnell RH.

Hum Mol Genet. 2018 Sep 25. doi: 10.1093/hmg/ddy339. [Epub ahead of print]


Application of machine-learning to predict early spontaneous preterm birth among nulliparous non-Hispanic black and white women.

Weber A, Darmstadt GL, Gruber S, Foeller ME, Carmichael SL, Stevenson DK, Shaw GM.

Ann Epidemiol. 2018 Aug 24. pii: S1047-2797(18)30494-0. doi: 10.1016/j.annepidem.2018.08.008. [Epub ahead of print]


Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome.

Goltsman DSA, Sun CL, Proctor DM, DiGiulio DB, Robaczewska A, Thomas BC, Shaw GM, Stevenson DK, Holmes SP, Banfield JF, Relman DA.

Genome Res. 2018 Oct;28(10):1467-1480. doi: 10.1101/gr.236000.118. Epub 2018 Sep 19.


Stillbirth and Live Birth at Periviable Gestational Age: A Comparison of Prevalence and Risk Factors.

Carmichael SL, Blumenfeld YJ, Mayo JA, Profit J, Shaw GM, Hintz SR, Stevenson DK.

Am J Perinatol. 2018 Sep 12. doi: 10.1055/s-0038-1670633. [Epub ahead of print]


Pre-ejection period, the reason why the electrocardiogram Q-wave is an unreliable indicator of pulse wave initialization.

Balmer J, Pretty C, Davidson S, Desaive T, Kamoi S, Pironet A, Morimont P, Janssen N, Lambermont B, Shaw GM, Chase JG.

Physiol Meas. 2018 Sep 24;39(9):095005. doi: 10.1088/1361-6579/aada72.


Epidemiology of anophthalmia and microphthalmia: Prevalence and patterns in Texas, 1999-2009.

Chambers TM, Agopian AJ, Lewis RA, Langlois PH, Danysh HE, Weber KA, Shaw GM, Mitchell LE, Lupo PJ.

Am J Med Genet A. 2018 Sep;176(9):1810-1818. doi: 10.1002/ajmg.a.40352. Epub 2018 Aug 2.


Change in Prevalence of Orofacial Clefts in California between 1987 and 2010.

Andrew T, Yang W, Bernstein JA, Shaw GM.

Am J Med Genet A. 2018 Sep;176(9):1910-1916. doi: 10.1002/ajmg.a.40384. Epub 2018 Jul 31.


Interpretation of Retrospective BG Measurements.

Stewart KW, Pretty CG, Shaw GM, Chase JG.

J Diabetes Sci Technol. 2018 Sep;12(5):967-975. doi: 10.1177/1932296818786518. Epub 2018 Jul 12.


Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence.

Ke R, Li H, Wang S, Ding W, Ribeiro RM, Giorgi EE, Bhattacharya T, Barnard RJO, Hahn BH, Shaw GM, Perelson AS.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7139-E7148. doi: 10.1073/pnas.1805267115. Epub 2018 Jul 9.


The uncertain fate of the National Institutes of Health (NIH) pediatric research portfolio: In support of an investment strategy to improve the public health of the nation through perinatal research.

Stevenson DK, Shaw GM, Katz M.

Pediatr Res. 2018 Jul 6. doi: 10.1038/s41390-018-0036-6. [Epub ahead of print] No abstract available.


Correction: Prediction of preterm birth with and without preeclampsia using mid-pregnancy immune and growth-related molecular factors and maternal characteristics.

Jelliffe-Pawlowski LL, Rand L, Bedell B, Baer RJ, Oltman SP, Norton ME, Shaw GM, Stevenson DK, Murray JC, Ryckman KK.

J Perinatol. 2018 Jul;38(7):946. doi: 10.1038/s41372-018-0158-z.


Natural Selection Has Differentiated the Progesterone Receptor among Human Populations.

Li J, Hong X, Mesiano S, Muglia LJ, Wang X, Snyder M, Stevenson DK, Shaw GM.

Am J Hum Genet. 2018 Jul 5;103(1):45-57. doi: 10.1016/j.ajhg.2018.05.009. Epub 2018 Jun 21.


Safe and effective glycaemic control in premature infants: observational clinical results from the computerised STAR-GRYPHON protocol.

Knopp JL, Lynn AM, Shaw GM, Chase JG.

Arch Dis Child Fetal Neonatal Ed. 2018 Jun 21. pii: fetalneonatal-2017-314072. doi: 10.1136/archdischild-2017-314072. [Epub ahead of print]


Maternal ambient heat exposure during early pregnancy in summer and spring and congenital heart defects - A large US population-based, case-control study.

Lin S, Lin Z, Ou Y, Soim A, Shrestha S, Lu Y, Sheridan S, Luben TJ, Fitzgerald E, Bell E, Shaw GM, Reefhuis J, Langlois PH, Romitti P, Feldkamp ML, Malik S, Pantea C, Nayak S, Hwang SA, Browne M; National Birth Defects Prevention Study.

Environ Int. 2018 Sep;118:211-221. doi: 10.1016/j.envint.2018.04.043. Epub 2018 Jun 8.


Noninvasive blood tests for fetal development predict gestational age and preterm delivery.

Ngo TTM, Moufarrej MN, Rasmussen MH, Camunas-Soler J, Pan W, Okamoto J, Neff NF, Liu K, Wong RJ, Downes K, Tibshirani R, Shaw GM, Skotte L, Stevenson DK, Biggio JR, Elovitz MA, Melbye M, Quake SR.

Science. 2018 Jun 8;360(6393):1133-1136. doi: 10.1126/science.aar3819.


Reproductive suppression, birth defects, and periviable birth.

Catalano R, Bruckner TA, Karasek D, Yang W, Shaw GM.

Evol Appl. 2018 Jan 10;11(5):762-767. doi: 10.1111/eva.12585. eCollection 2018 Jun.


Prediction of preterm birth with and without preeclampsia using mid-pregnancy immune and growth-related molecular factors and maternal characteristics.

Jelliffe-Pawlowski LL, Rand L, Bedell B, Baer RJ, Oltman SP, Norton ME, Shaw GM, Stevenson DK, Murray JC, Ryckman KK.

J Perinatol. 2018 Aug;38(8):963-972. doi: 10.1038/s41372-018-0112-0. Epub 2018 May 24. Erratum in: J Perinatol. 2018 Jul;38(7):946.


Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection.

Song H, Giorgi EE, Ganusov VV, Cai F, Athreya G, Yoon H, Carja O, Hora B, Hraber P, Romero-Severson E, Jiang C, Li X, Wang S, Li H, Salazar-Gonzalez JF, Salazar MG, Goonetilleke N, Keele BF, Montefiori DC, Cohen MS, Shaw GM, Hahn BH, McMichael AJ, Haynes BF, Korber B, Bhattacharya T, Gao F.

Nat Commun. 2018 May 15;9(1):1928. doi: 10.1038/s41467-018-04217-5.


Women's periconceptional diet and risk of biliary atresia in offspring.

Carmichael SL, Ma C, Van Zutphen AR, Moore CA, Shaw GM; National Birth Defects Prevention Study.

Birth Defects Res. 2018 Jul 17;110(12):994-1000. doi: 10.1002/bdr2.1340. Epub 2018 May 15.


Failed umbilical artery catheterization and adverse outcomes in extremely low birth weight infants.

Wallenstein MB, Shaw GM, Yang W, Stevenson DK.

J Matern Fetal Neonatal Med. 2018 May 2:1-5. doi: 10.1080/14767058.2018.1468430. [Epub ahead of print]


Genetic variation in biotransformation enzymes, air pollution exposures, and risk of spina bifida.

Padula AM, Yang W, Schultz K, Lurmann F, Hammond SK, Shaw GM.

Am J Med Genet A. 2018 May;176(5):1055-1090. doi: 10.1002/ajmg.a.38661.


Herpesvirus Infection in Infants with Gastroschisis.

Francis SS, Wiemels JL, Yang W, Shaw GM.

Epidemiology. 2018 Jul;29(4):571-573. doi: 10.1097/EDE.0000000000000844.


Residential agricultural pesticide exposures and risks of preeclampsia.

Shaw GM, Yang W, Roberts EM, Aghaeepour N, Mayo JA, Weber KA, Maric I, Carmichael SL, Winn VD, Stevenson DK, English PB.

Environ Res. 2018 Jul;164:546-555. doi: 10.1016/j.envres.2018.03.020. Epub 2018 Mar 31.


Nutrient intake in women before conception and risks of anophthalmia and microphthalmia in their offspring.

Weber KA, Yang W, Carmichael SL, Shaw GM; National Birth Defects Prevention Study.

Birth Defects Res. 2018 Jun 1;110(10):863-870. doi: 10.1002/bdr2.1201. Epub 2018 Mar 5.


Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them.

Chase JG, Preiser JC, Dickson JL, Pironet A, Chiew YS, Pretty CG, Shaw GM, Benyo B, Moeller K, Safaei S, Tawhai M, Hunter P, Desaive T.

Biomed Eng Online. 2018 Feb 20;17(1):24. doi: 10.1186/s12938-018-0455-y. Review.


Nutrition delivery of a model-based ICU glycaemic control system.

Stewart KW, Chase JG, Pretty CG, Shaw GM.

Ann Intensive Care. 2018 Jan 10;8(1):4. doi: 10.1186/s13613-017-0351-9.


A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth.

Rappoport N, Toung J, Hadley D, Wong RJ, Fujioka K, Reuter J, Abbott CW, Oh S, Hu D, Eng C, Huntsman S, Bodian DL, Niederhuber JE, Hong X, Zhang G, Sikora-Wohfeld W, Gignoux CR, Wang H, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Darmstadt GL, Wang X, Bustamante CD, Snyder MP, Ziv E, Patsopoulos NA, Muglia LJ, Burchard E, Shaw GM, O'Brodovich HM, Stevenson DK, Butte AJ, Sirota M.

Sci Rep. 2018 Jan 9;8(1):226. doi: 10.1038/s41598-017-18246-5.


A proteomic clock of human pregnancy.

Aghaeepour N, Lehallier B, Baca Q, Ganio EA, Wong RJ, Ghaemi MS, Culos A, El-Sayed YY, Blumenfeld YJ, Druzin ML, Winn VD, Gibbs RS, Tibshirani R, Shaw GM, Stevenson DK, Gaudilliere B, Angst MS.

Am J Obstet Gynecol. 2018 Mar;218(3):347.e1-347.e14. doi: 10.1016/j.ajog.2017.12.208. Epub 2017 Dec 24.


First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring.

Helle EIT, Biegley P, Knowles JW, Leader JB, Pendergrass S, Yang W, Reaven GR, Shaw GM, Ritchie M, Priest JR.

J Pediatr. 2018 Apr;195:275-278. doi: 10.1016/j.jpeds.2017.10.046. Epub 2017 Dec 15.


Divergent Patterns of Mitochondrial and Nuclear Ancestry Are Associated with the Risk for Preterm Birth.

Crawford N, Prendergast D, Oehlert JW, Shaw GM, Stevenson DK, Rappaport N, Sirota M, Tishkoff SA, Sondheimer N.

J Pediatr. 2018 Mar;194:40-46.e4. doi: 10.1016/j.jpeds.2017.10.052. Epub 2017 Dec 14.


Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes.

Carr AC, Rosengrave PC, Bayer S, Chambers S, Mehrtens J, Shaw GM.

Crit Care. 2017 Dec 11;21(1):300. doi: 10.1186/s13054-017-1891-y.


Copy number variants in Ebstein anomaly.

Giannakou A, Sicko RJ, Zhang W, Romitti P, Browne ML, Caggana M, Brody LC, Jelliffe-Pawlowski L, Shaw GM, Kay DM, Mills JL.

PLoS One. 2017 Dec 7;12(12):e0188168. doi: 10.1371/journal.pone.0188168. eCollection 2017.


Risky Business: Meeting the Structural Needs of Transdisciplinary Science.

Wise PH, Shaw GM, Druzin ML, Darmstadt GL, Quaintance C, Mäkinen E, Relman DA, Quake SR, Butte AJ, Angst MS, Muglia LJ, Macones G, Driscoll D, Ober C, Simpson JL, Katz M, Howse J, Stevenson DK.

J Pediatr. 2017 Dec;191:255-258. doi: 10.1016/j.jpeds.2017.08.072. No abstract available.


Wild bonobos host geographically restricted malaria parasites including a putative new Laverania species.

Liu W, Sherrill-Mix S, Learn GH, Scully EJ, Li Y, Avitto AN, Loy DE, Lauder AP, Sundararaman SA, Plenderleith LJ, Ndjango JN, Georgiev AV, Ahuka-Mundeke S, Peeters M, Bertolani P, Dupain J, Garai C, Hart JA, Hart TB, Shaw GM, Sharp PM, Hahn BH.

Nat Commun. 2017 Nov 21;8(1):1635. doi: 10.1038/s41467-017-01798-5.


Out-of-hospital births in California 1991-2011.

Girsen AI, Mayo JA, Lyell DJ, Blumenfeld YJ, Stevenson DK, El-Sayed YY, Shaw GM, Druzin ML.

J Perinatol. 2018 Jan;38(1):41-45. doi: 10.1038/jp.2017.156. Epub 2017 Nov 9.


Continuous Glucose Monitoring Measures Can Be Used for Glycemic Control in the ICU: An In-Silico Study.

Zhou T, Dickson JL, Shaw GM, Chase JG.

J Diabetes Sci Technol. 2018 Jan;12(1):7-19. doi: 10.1177/1932296817738791. Epub 2017 Nov 6.


Occurrence of Selected Structural Birth Defects Among Women With Preeclampsia and Other Hypertensive Disorders.

Weber KA, Mayo JA, Carmichael SL, Stevenson DK, Winn VD, Shaw GM.

Am J Epidemiol. 2018 Apr 1;187(4):668-676. doi: 10.1093/aje/kwx269.


Residential Agricultural Pesticide Exposures and Risks of Spontaneous Preterm Birth.

Shaw GM, Yang W, Roberts EM, Kegley SE, Stevenson DK, Carmichael SL, English PB.

Epidemiology. 2018 Jan;29(1):8-21. doi: 10.1097/EDE.0000000000000757.


Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.

Kijak GH, Sanders-Buell E, Chenine AL, Eller MA, Goonetilleke N, Thomas R, Leviyang S, Harbolick EA, Bose M, Pham P, Oropeza C, Poltavee K, O'Sullivan AM, Billings E, Merbah M, Costanzo MC, Warren JA, Slike B, Li H, Peachman KK, Fischer W, Gao F, Cicala C, Arthos J, Eller LA, O'Connell RJ, Sinei S, Maganga L, Kibuuka H, Nitayaphan S, Rao M, Marovich MA, Krebs SJ, Rolland M, Korber BT, Shaw GM, Michael NL, Robb ML, Tovanabutra S, Kim JH.

PLoS Pathog. 2017 Sep 14;13(9):e1006620. doi: 10.1371/journal.ppat.1006620. eCollection 2017 Sep.


Simultaneously Monitoring Immune Response and Microbial Infections during Pregnancy through Plasma cfRNA Sequencing.

Pan W, Ngo TTM, Camunas-Soler J, Song CX, Kowarsky M, Blumenfeld YJ, Wong RJ, Shaw GM, Stevenson DK, Quake SR.

Clin Chem. 2017 Nov;63(11):1695-1704. doi: 10.1373/clinchem.2017.273888. Epub 2017 Sep 13.


A Multivariate Dynamic Spatial Factor Model for Speciated Pollutants and Adverse Birth Outcomes.

Kaufeld KA, Fuentes M, Reich BJ, Herring AH, Shaw GM, Terres MA.

Int J Environ Res Public Health. 2017 Sep 11;14(9). pii: E1046. doi: 10.3390/ijerph14091046.


Antioxidant Consumption is Associated with Decreased Odds of Congenital Limb Deficiencies.

Pace ND, Desrosiers TA, Carmichael SL, Shaw GM, Olshan AF, Siega-Riz AM; National Birth Defects Prevention Study.

Paediatr Perinat Epidemiol. 2018 Jan;32(1):90-99. doi: 10.1111/ppe.12403. Epub 2017 Sep 4.


An immune clock of human pregnancy.

Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, El-Sayed YY, Quaintance C, Gibbs R, Darmstadt GL, Shaw GM, Stevenson DK, Tibshirani R, Nolan GP, Lewis DB, Angst MS, Gaudilliere B.

Sci Immunol. 2017 Sep 1;2(15). pii: eaan2946. doi: 10.1126/sciimmunol.aan2946.


Replication and refinement of a vaginal microbial signature of preterm birth in two racially distinct cohorts of US women.

Callahan BJ, DiGiulio DB, Goltsman DSA, Sun CL, Costello EK, Jeganathan P, Biggio JR, Wong RJ, Druzin ML, Shaw GM, Stevenson DK, Holmes SP, Relman DA.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9966-9971. doi: 10.1073/pnas.1705899114. Epub 2017 Aug 28.

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