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Items: 41

1.

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

Maurizio PL, Ferris MT, Keele GR, Miller DR, Shaw GD, Whitmore AC, West A, Morrison CR, Noll KE, Plante KS, Cockrell AS, Threadgill DW, Pardo-Manuel de Villena F, Baric RS, Heise MT, Valdar W.

G3 (Bethesda). 2018 Feb 2;8(2):427-445. doi: 10.1534/g3.117.300438.

2.

Glycoprotein IbĪ± inhibitor (CCP-224) prevents neutrophil-platelet aggregation in Sickle Cell Disease.

Jimenez MA, Novelli E, Shaw GD, Sundd P.

Blood Adv. 2017 Sep 12;1(20):1712-1716. doi: 10.1182/bloodadvances.2017006742. No abstract available.

3.

Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross.

Shorter JR, Odet F, Aylor DL, Pan W, Kao CY, Fu CP, Morgan AP, Greenstein S, Bell TA, Stevans AM, Feathers RW, Patel S, Cates SE, Shaw GD, Miller DR, Chesler EJ, McMillian L, O'Brien DA, Villena FP.

Genetics. 2017 Jun;206(2):557-572. doi: 10.1534/genetics.116.199596.

4.

A Soluble Form of P Selectin Glycoprotein Ligand 1 Requires Signaling by Nuclear Factor Erythroid 2-Related Factor 2 to Protect Liver Transplant Endothelial Cells Against Ischemia-Reperfusion Injury.

Zhang C, Zhang Y, Liu Y, Liu Y, Kageyama S, Shen XD, Gao F, Zheng S, Busuttil RW, Shaw GD, Ji H, Kupiec-Weglinski JW.

Am J Transplant. 2017 Jun;17(6):1462-1475. doi: 10.1111/ajt.14159. Epub 2017 Feb 6.

5.

IsoDOT Detects Differential RNA-isoform Expression/Usage with respect to a Categorical or Continuous Covariate with High Sensitivity and Specificity.

Sun W, Liu Y, Crowley JJ, Chen TH, Zhou H, Chu H, Huang S, Kuan PF, Li Y, Miller DR, Shaw GD, Wu Y, Zhabotynsky V, McMillan L, Zou F, Sullivan PF, de Villena FP.

J Am Stat Assoc. 2015;110(511):975-986. Epub 2015 Nov 7.

6.

Corrigendum: analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, Gooch TJ, Hansen SD, Robinson NN, Shaw GD, Spence JS, Quackenbush CR, Barrick CJ, Nonneman RJ, Kim K, Xenakis J, Xie Y, Valdar W, Lenarcic AB, Wang W, Welsh CE, Fu CP, Zhang Z, Holt J, Guo Z, Threadgill DW, Tarantino LM, Miller DR, Zou F, McMillan L, Sullivan PF, de Villena FP.

Nat Genet. 2015 Jun;47(6):690. doi: 10.1038/ng0615-690a. No abstract available.

PMID:
26018903
7.

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, Gooch TJ, Hansen SD, Robinson NN, Shaw GD, Spence JS, Quackenbush CR, Barrick CJ, Nonneman RJ, Kim K, Xenakis J, Xie Y, Valdar W, Lenarcic AB, Wang W, Welsh CE, Fu CP, Zhang Z, Holt J, Guo Z, Threadgill DW, Tarantino LM, Miller DR, Zou F, McMillan L, Sullivan PF, Pardo-Manuel de Villena F.

Nat Genet. 2015 Apr;47(4):353-60. doi: 10.1038/ng.3222. Epub 2015 Mar 2. Erratum in: Nat Genet. 2015 Jun;47(6):690.

8.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.

9.

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG.

Science. 2014 Nov 21;346(6212):987-91. doi: 10.1126/science.1259595. Epub 2014 Oct 30.

10.

Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.

Huang A, Moretto A, Janz K, Lowe M, Bedard PW, Tam S, Di L, Clerin V, Sushkova N, Tchernychev B, Tsao DH, Keith JC, Shaw GD, Schaub RG, Wang Q, Kaila N.

J Med Chem. 2010 Aug 26;53(16):6003-17. doi: 10.1021/jm9013696.

PMID:
20718494
11.

Identification of peptide antagonists to glycoprotein Ibalpha that selectively inhibit von Willebrand factor dependent platelet aggregation.

Benard SA, Smith TM, Cunningham K, Jacob J, DeSilva T, Lin L, Shaw GD, Kriz R, Kelleher KS.

Biochemistry. 2008 Apr 22;47(16):4674-82. doi: 10.1021/bi702428q. Epub 2008 Mar 26.

PMID:
18363340
12.

SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1.

Schaff UY, Shih HH, Lorenz M, Sako D, Kriz R, Milarski K, Bates B, Tchernychev B, Shaw GD, Simon SI.

Eur J Immunol. 2008 Feb;38(2):550-64. doi: 10.1002/eji.200737777.

13.

Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis.

Bedard PW, Clerin V, Sushkova N, Tchernychev B, Antrilli T, Resmini C, Keith JC Jr, Hennan JK, Kaila N, Debernardo S, Janz K, Wang Q, Crandall DL, Schaub RG, Shaw GD, Carter LL.

J Pharmacol Exp Ther. 2008 Feb;324(2):497-506. Epub 2007 Nov 16.

14.

The von Willebrand factor antagonist (GPG-290) prevents coronary thrombosis without prolongation of bleeding time.

Wadanoli M, Sako D, Shaw GD, Schaub RG, Wang Q, Tchernychev B, Xu J, Porter TJ, Huang Q.

Thromb Haemost. 2007 Aug;98(2):397-405.

PMID:
17721623
15.

Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation.

Myers DD Jr, Wrobleski SK, Longo C, Bedard PW, Kaila N, Shaw GD, Londy FJ, Rohrer SE, Fex BA, Zajkowski PJ, Meier TR, Hawley AE, Farris DM, Ballard NE, Henke PK, Schaub RG, Wakefield TW.

Thromb Haemost. 2007 Mar;97(3):400-7.

PMID:
17334507
16.

2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic acid (PSI-697): identification of a clinical candidate from the quinoline salicylic acid series of P-selectin antagonists.

Kaila N, Janz K, Huang A, Moretto A, DeBernardo S, Bedard PW, Tam S, Clerin V, Keith JC Jr, Tsao DH, Sushkova N, Shaw GD, Camphausen RT, Schaub RG, Wang Q.

J Med Chem. 2007 Jan 11;50(1):40-64.

PMID:
17201409
17.

Effect of von Willebrand factor on the pharmacokinetics of recombinant human platelet glycoprotein Ibalpha-immunoglobulin G1 chimeric proteins.

Wang Q, Shorten D, Xu X, Shaw GD, Schaub RG, Shea C, Brooks J, Sako D, Wiswall E, Xu J, Szklut P, Patel VS.

Pharm Res. 2006 Aug;23(8):1743-9.

PMID:
16850270
18.

Pharmacologic inhibition of platelet vWF-GPIb alpha interaction prevents coronary artery thrombosis.

Hennan JK, Swillo RE, Morgan GA, Leik CE, Brooks JM, Shaw GD, Schaub RG, Crandall DL, Vlasuk GP.

Thromb Haemost. 2006 Mar;95(3):469-75.

PMID:
16525575
19.

Molecular characterization of rat leukocyte P-selectin glycoprotein ligand-1 and effect of its blockade: protection from ischemia-reperfusion injury in liver transplantation.

Tsuchihashi S, Fondevila C, Shaw GD, Lorenz M, Marquette K, Benard S, Shen XD, Ke B, Busuttil RW, Kupiec-Weglinski JW.

J Immunol. 2006 Jan 1;176(1):616-24.

20.

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice.

Michaud EJ, Culiat CT, Klebig ML, Barker PE, Cain KT, Carpenter DJ, Easter LL, Foster CM, Gardner AW, Guo ZY, Houser KJ, Hughes LA, Kerley MK, Liu Z, Olszewski RE, Pinn I, Shaw GD, Shinpock SG, Wymore AM, Rinchik EM, Johnson DK.

BMC Genomics. 2005 Nov 21;6:164.

21.

Decreased venous thrombosis with an oral inhibitor of P selectin.

Myers DD Jr, Rectenwald JE, Bedard PW, Kaila N, Shaw GD, Schaub RG, Farris DM, Hawley AE, Wrobleski SK, Henke PK, Wakefield TW.

J Vasc Surg. 2005 Aug;42(2):329-36.

22.

Selectin blockade plus therapy with low-dose sirolimus and cyclosporin a prevent brain death-induced renal allograft dysfunction.

Gasser M, Waaga-Gasser AM, Grimm MW, Grimm MR, Lenhard MS, Kist-van Holthe JE, Laskowski I, Shaw GD, Thiede A, Hancock WW, Tilney NL.

Am J Transplant. 2005 Apr;5(4 Pt 1):662-70.

23.

CD62 blockade with P-Selectin glycoprotein ligand-immunoglobulin fusion protein reduces ischemia-reperfusion injury after rat intestinal transplantation.

Farmer DG, Shen XD, Amersi F, Anselmo D, Ma JP, Ke B, Gao F, Dry S, Fernandez S, Shaw GD, McDiarmid SV, Busuttil RW, Kupiec-Weglinski J.

Transplantation. 2005 Jan 15;79(1):44-51.

PMID:
15714168
24.

Improvements in early behaviour of kidney allografts after donor treatment.

Pratschke J, Kofla G, Wilhelm M, Vergopoulos A, Laskowski I, Shaw GD, Tullius SG, Volk HD, Neuhous P, Tilney NL.

Transplant Proc. 2002 Sep;34(6):2213-4. No abstract available.

PMID:
12270368
25.

P-selectin glycoprotein ligand-1 (rPSGL-Ig)-mediated blockade of CD62 selectin molecules protects rat steatotic liver grafts from ischemia/reperfusion injury.

Amersi F, Farmer DG, Shaw GD, Kato H, Coito AJ, Kaldas F, Zhao D, Lassman CR, Melinek J, Ma J, Volk HD, Kupiec-Weglinski JW, Busuttil RW.

Am J Transplant. 2002 Aug;2(7):600-8.

26.

CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients.

Coito AJ, Shaw GD, Meng L, Moore C, Ma J, Busuttil RW, Kupiec-Weglinski JW.

Transplant Proc. 2002 Aug;34(5):1463-4. No abstract available.

PMID:
12176441
27.

Normalization of brain death-induced injury to rat renal allografts by recombinant soluble P-selectin glycoprotein ligand.

Gasser M, Waaga AM, Kist-Van Holthe JE, Lenhard SM, Laskowski I, Shaw GD, Hancock WW, Tilney NL.

J Am Soc Nephrol. 2002 Jul;13(7):1937-45.

28.

Selectin-mediated interactions regulate cytokine networks and macrophage heme oxygenase-1 induction in cardiac allograft recipients.

Coito AJ, Shaw GD, Li J, Ke B, Ma J, Busuttil RW, Kupiec-Weglinski JW.

Lab Invest. 2002 Jan;82(1):61-70.

PMID:
11796826
29.

Improvements in early behavior of rat kidney allografts after treatment of the brain-dead donor.

Pratschke J, Kofla G, Wilhelm MJ, Vergopoulos A, Laskowski I, Shaw GD, Tullius SG, Volk HD, Neuhaus P, Tilney NL.

Ann Surg. 2001 Dec;234(6):732-40.

30.

A novel iron chelator in combination with a P-selectin antagonist prevents ischemia/reperfusion injury in a rat liver model.

Amersi F, Dulkanchainun T, Nelson SK, Farmer DG, Kato H, Zaky J, Melinek J, Shaw GD, Kupiec-Weglinski JW, Horwitz LD, Horwitz MA, Busuttil RW.

Transplantation. 2001 Jan 15;71(1):112-8.

PMID:
11211175
31.

Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.

Somers WS, Tang J, Shaw GD, Camphausen RT.

Cell. 2000 Oct 27;103(3):467-79. Erratum in: Cell 2001 Jun 29;105(7):971.

33.

Effects of explosive brain death on cytokine activation of peripheral organs in the rat.

Takada M, Nadeau KC, Hancock WW, Mackenzie HS, Shaw GD, Waaga AM, Chandraker A, Sayegh MH, Tilney NL.

Transplantation. 1998 Jun 27;65(12):1533-42.

PMID:
9665067
34.

Reduction of hepatic ischemia/reperfusion injury by a soluble P-selectin glycoprotein ligand-1.

Dulkanchainun TS, Goss JA, Imagawa DK, Shaw GD, Anselmo DM, Kaldas F, Wang T, Zhao D, Busuttil AA, Kato H, Murray NG, Kupiec-Weglinski JW, Busuttil RW.

Ann Surg. 1998 Jun;227(6):832-40.

35.

Influence of initial antigen-independent events on acute allograft rejection: inhibition by a soluble P-selectin ligand and low-dose cyclosporine in combination.

Kusaka M, Nadeau KC, Takada M, Nagano H, Shaw GD, Tilney NL.

Transplant Proc. 1998 Jun;30(4):1027-8. No abstract available.

PMID:
9636414
36.

Prevention of late renal changes after initial ischemia/reperfusion injury by blocking early selectin binding.

Takada M, Nadeau KC, Shaw GD, Tilney NL.

Transplantation. 1997 Dec 15;64(11):1520-5.

PMID:
9415550
37.

The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand.

Takada M, Nadeau KC, Shaw GD, Marquette KA, Tilney NL.

J Clin Invest. 1997 Jun 1;99(11):2682-90.

38.

Early cellular and molecular changes in ischemia/reperfusion injury: inhibition by a selectin antagonist, P-selectin glycoprotein ligand-1.

Takada M, Nadeau KC, Shaw GD, Tilney NL.

Transplant Proc. 1997 Feb-Mar;29(1-2):1324-5. No abstract available.

PMID:
9123325
39.

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding.

Sako D, Comess KM, Barone KM, Camphausen RT, Cumming DA, Shaw GD.

Cell. 1995 Oct 20;83(2):323-31.

40.

Structure and expression of cloned murine IFN-alpha genes.

Shaw GD, Boll W, Taira H, Mantei N, Lengyel P, Weissmann C.

Nucleic Acids Res. 1983 Feb 11;11(3):555-73.

41.

Zambia: contagious bovine pleuro pneumonia 1970 outbreak: progress report April 1971.

Shaw GD.

Bull Epizoot Dis Afr. 1972 Jun;20:85-7. No abstract available.

PMID:
4658766

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