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Items: 1 to 50 of 63

1.

Autonomous early detection of eye disease in childhood photographs.

Munson MC, Plewman DL, Baumer KM, Henning R, Zahler CT, Kietzman AT, Beard AA, Mukai S, Diller L, Hamerly G, Shaw BF.

Sci Adv. 2019 Oct 2;5(10):eaax6363. doi: 10.1126/sciadv.aax6363. eCollection 2019 Oct.

2.

What Are We Missing by Not Measuring the Net Charge of Proteins?

Zahler CT, Shaw BF.

Chemistry. 2019 Jun 7;25(32):7581-7590. doi: 10.1002/chem.201900178. Epub 2019 Apr 10. Review.

PMID:
30779227
3.

Glycerolipid Headgroups Control Rate and Mechanism of Superoxide Dismutase-1 Aggregation and Accelerate Fibrillization of Slowly Aggregating Amyotrophic Lateral Sclerosis Mutants.

Rasouli S, Abdolvahabi A, Croom CM, Plewman DL, Shi Y, Shaw BF.

ACS Chem Neurosci. 2018 Jul 18;9(7):1743-1756. doi: 10.1021/acschemneuro.8b00086. Epub 2018 Apr 20.

PMID:
29649360
4.

Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer.

Zahler CT, Zhou H, Abdolvahabi A, Holden RL, Rasouli S, Tao P, Shaw BF.

Angew Chem Int Ed Engl. 2018 May 4;57(19):5364-5368. doi: 10.1002/anie.201712306. Epub 2018 Mar 25.

5.

Lysine acylation in superoxide dismutase-1 electrostatically inhibits formation of fibrils with prion-like seeding.

Rasouli S, Abdolvahabi A, Croom CM, Plewman DL, Shi Y, Ayers JI, Shaw BF.

J Biol Chem. 2017 Nov 24;292(47):19366-19380. doi: 10.1074/jbc.M117.805283. Epub 2017 Oct 3.

6.

Kaplan-Meier Meets Chemical Kinetics: Intrinsic Rate of SOD1 Amyloidogenesis Decreased by Subset of ALS Mutations and Cannot Fully Explain Age of Disease Onset.

Abdolvahabi A, Shi Y, Rasouli S, Croom CM, Aliyan A, Martí AA, Shaw BF.

ACS Chem Neurosci. 2017 Jun 21;8(6):1378-1389. doi: 10.1021/acschemneuro.7b00029. Epub 2017 Mar 23.

PMID:
28290665
7.

How Do Gyrating Beads Accelerate Amyloid Fibrillization?

Abdolvahabi A, Shi Y, Rasouli S, Croom CM, Chuprin A, Shaw BF.

Biophys J. 2017 Jan 24;112(2):250-264. doi: 10.1016/j.bpj.2016.12.004.

8.

Gibbs Energy of Superoxide Dismutase Heterodimerization Accounts for Variable Survival in Amyotrophic Lateral Sclerosis.

Shi Y, Acerson MJ, Abdolvahabi A, Mowery RA, Shaw BF.

J Am Chem Soc. 2016 Apr 27;138(16):5351-62. doi: 10.1021/jacs.6b01742. Epub 2016 Apr 18.

PMID:
27054659
9.

Stochastic Formation of Fibrillar and Amorphous Superoxide Dismutase Oligomers Linked to Amyotrophic Lateral Sclerosis.

Abdolvahabi A, Shi Y, Chuprin A, Rasouli S, Shaw BF.

ACS Chem Neurosci. 2016 Jun 15;7(6):799-810. doi: 10.1021/acschemneuro.6b00048. Epub 2016 Mar 31.

PMID:
26979728
10.

Voltage-Induced Misfolding of Zinc-Replete ALS Mutant Superoxide Dismutase-1.

Shi Y, Acerson MJ, Shuford KL, Shaw BF.

ACS Chem Neurosci. 2015 Oct 21;6(10):1696-707. doi: 10.1021/acschemneuro.5b00146. Epub 2015 Aug 5.

PMID:
26207449
11.

Arresting amyloid with coulomb's law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation.

Abdolvahabi A, Shi Y, Rhodes NR, Cook NP, Martí AA, Shaw BF.

Biophys J. 2015 Mar 10;108(5):1199-212. doi: 10.1016/j.bpj.2015.01.014.

12.

Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.

Sea K, Sohn SH, Durazo A, Sheng Y, Shaw BF, Cao X, Taylor AB, Whitson LJ, Holloway SP, Hart PJ, Cabelli DE, Gralla EB, Valentine JS.

J Biol Chem. 2015 Jan 23;290(4):2405-18. doi: 10.1074/jbc.M114.588798. Epub 2014 Nov 28.

13.

Metal-ion-specific screening of charge effects in protein amide H/D exchange and the Hofmeister series.

Abdolvahabi A, Gober JL, Mowery RA, Shi Y, Shaw BF.

Anal Chem. 2014 Oct 21;86(20):10303-10. doi: 10.1021/ac502714v. Epub 2014 Sep 29.

PMID:
25207790
14.

Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings.

Rivas-Perea P, Baker E, Hamerly G, Shaw BF.

BMC Ophthalmol. 2014 Sep 9;14:110. doi: 10.1186/1471-2415-14-110.

15.

Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values.

Shi Y, Abdolvahabi A, Shaw BF.

Protein Sci. 2014 Oct;23(10):1417-33. doi: 10.1002/pro.2526. Epub 2014 Aug 7.

16.

Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma.

Abdolvahabi A, Taylor BW, Holden RL, Shaw EV, Kentsis A, Rodriguez-Galindo C, Mukai S, Shaw BF.

PLoS One. 2013 Oct 30;8(10):e76677. doi: 10.1371/journal.pone.0076677. eCollection 2013.

17.

Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations.

Shi Y, Rhodes NR, Abdolvahabi A, Kohn T, Cook NP, Marti AA, Shaw BF.

J Am Chem Soc. 2013 Oct 23;135(42):15897-908. doi: 10.1021/ja407801x. Epub 2013 Oct 10.

PMID:
24066782
18.

Effect of metal loading and subcellular pH on net charge of superoxide dismutase-1.

Shi Y, Mowery RA, Shaw BF.

J Mol Biol. 2013 Nov 15;425(22):4388-404. doi: 10.1016/j.jmb.2013.07.018. Epub 2013 Jul 17.

PMID:
23871896
19.

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site.

Alves NJ, Champion MM, Stefanick JF, Handlogten MW, Moustakas DT, Shi Y, Shaw BF, Navari RM, Kiziltepe T, Bilgicer B.

Biomaterials. 2013 Jul;34(22):5700-10. doi: 10.1016/j.biomaterials.2013.03.082. Epub 2013 Apr 16.

PMID:
23601661
20.

Ligand-induced protein mobility in complexes of carbonic anhydrase II and benzenesulfonamides with oligoglycine chains.

Krishnamurthy VM, Raman VS, Mowery RA, Hentz M, Baleja JD, Shaw BF, Kumar K.

PLoS One. 2013;8(3):e57629. doi: 10.1371/journal.pone.0057629. Epub 2013 Mar 5.

21.

Effect of surfactant hydrophobicity on the pathway for unfolding of ubiquitin.

Shaw BF, Schneider GF, Whitesides GM.

J Am Chem Soc. 2012 Nov 14;134(45):18739-45. doi: 10.1021/ja3079863. Epub 2012 Oct 31.

22.

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding.

Shi Y, Mowery RA, Ashley J, Hentz M, Ramirez AJ, Bilgicer B, Slunt-Brown H, Borchelt DR, Shaw BF.

Protein Sci. 2012 Aug;21(8):1197-209. doi: 10.1002/pro.2107.

23.

Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants.

Shaw BF, Schneider GF, Arthanari H, Narovlyansky M, Moustakas D, Durazo A, Wagner G, Whitesides GM.

J Am Chem Soc. 2011 Nov 9;133(44):17681-95. doi: 10.1021/ja205735q. Epub 2011 Oct 13.

24.

Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.

Shaw BF, Arthanari H, Narovlyansky M, Durazo A, Frueh DP, Pollastri MP, Lee A, Bilgicer B, Gygi SP, Wagner G, Whitesides GM.

J Am Chem Soc. 2010 Dec 15;132(49):17411-25. doi: 10.1021/ja9067035. Epub 2010 Nov 19.

25.

Taking charge of proteins from neurodegeneration to industrial biotechnology.

Shaw BF, Moustakas DT, Whitelegge JP, Faull KF.

Adv Protein Chem Struct Biol. 2010;79:127-64. doi: 10.1016/S1876-1623(10)79004-0. Review.

PMID:
20621283
26.

Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature.

Durazo A, Shaw BF, Chattopadhyay M, Faull KF, Nersissian AM, Valentine JS, Whitelegge JP.

J Biol Chem. 2009 Dec 4;284(49):34382-9. doi: 10.1074/jbc.M109.052076. Epub 2009 Oct 5.

27.

Phase separation of 2D meso-scale Coulombic crystals from meso-scale polarizable "solvent"

Kaufman GK, Thomas SW, Reches M, Shaw BF, Feng J, Whitesides GM.

Soft Matter. 2009 Jan 1;5:1188-1191.

28.

A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids.

Bilgiçer B, Thomas SW 3rd, Shaw BF, Kaufman GK, Krishnamurthy VM, Estroff LA, Yang J, Whitesides GM.

J Am Chem Soc. 2009 Jul 8;131(26):9361-7. doi: 10.1021/ja9023836.

29.

Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.

Oztug Durer ZA, Cohlberg JA, Dinh P, Padua S, Ehrenclou K, Downes S, Tan JK, Nakano Y, Bowman CJ, Hoskins JL, Kwon C, Mason AZ, Rodriguez JA, Doucette PA, Shaw BF, Valentine JS.

PLoS One. 2009;4(3):e5004. doi: 10.1371/journal.pone.0005004. Epub 2009 Mar 27.

30.

Pathway for unfolding of ubiquitin in sodium dodecyl sulfate, studied by capillary electrophoresis.

Schneider GF, Shaw BF, Lee A, Carillho E, Whitesides GM.

J Am Chem Soc. 2008 Dec 24;130(51):17384-93. doi: 10.1021/ja804736t.

31.

Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation.

Shaw BF, Schneider GF, Bilgiçer B, Kaufman GK, Neveu JM, Lane WS, Whitelegge JP, Whitesides GM.

Protein Sci. 2008 Aug;17(8):1446-55. doi: 10.1110/ps.035154.108. Epub 2008 May 1.

32.

Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1.

Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari A, Hayward LJ, Borchelt DR, Valentine JS, Whitelegge JP.

J Biol Chem. 2008 Mar 28;283(13):8340-50. doi: 10.1074/jbc.M707751200. Epub 2008 Jan 11.

33.

Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein.

Potter SZ, Zhu H, Shaw BF, Rodriguez JA, Doucette PA, Sohn SH, Durazo A, Faull KF, Gralla EB, Nersissian AM, Valentine JS.

J Am Chem Soc. 2007 Apr 18;129(15):4575-83. Epub 2007 Mar 24.

PMID:
17381088
34.

How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein?

Shaw BF, Valentine JS.

Trends Biochem Sci. 2007 Feb;32(2):78-85. Epub 2007 Jan 5. Review.

PMID:
17208444
35.

Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry.

Shaw BF, Durazo A, Nersissian AM, Whitelegge JP, Faull KF, Valentine JS.

J Biol Chem. 2006 Jun 30;281(26):18167-76. Epub 2006 Apr 26.

36.

Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis.

Rodriguez JA, Shaw BF, Durazo A, Sohn SH, Doucette PA, Nersissian AM, Faull KF, Eggers DK, Tiwari A, Hayward LJ, Valentine JS.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10516-21. Epub 2005 Jul 14.

37.

Psychological responses to prenatal NTS counseling and the uptake of invasive testing in women of advanced maternal age.

Kaiser AS, Ferris LE, Katz R, Pastuszak A, Llewellyn-Thomas H, Johnson JA, Shaw BF.

Patient Educ Couns. 2004 Jul;54(1):45-53.

PMID:
15210259
39.

The patient's motivation in seeking complementary therapies.

Ritvo P, Irvine J, Katz J, Matthew A, Sacamano J, Shaw BF.

Patient Educ Couns. 1999 Oct;38(2):161-5. Review.

PMID:
14560712
40.

The effects of prenatal group genetic counselling on knowledge, anxiety and decisional conflict: issues for nuchal translucency screening.

Kaiser AS, Ferris LE, Pastuszak AL, Llewellyn-Thomas H, Johnson JA, Conacher S, Shaw BF.

J Obstet Gynaecol. 2002 May;22(3):246-55.

PMID:
12521493
41.

Therapist competence ratings in relation to clinical outcome in cognitive therapy of depression.

Shaw BF, Elkin I, Yamaguchi J, Olmsted M, Vallis TM, Dobson KS, Lowery A, Sotsky SM, Watkins JT, Imber SD.

J Consult Clin Psychol. 1999 Dec;67(6):837-46.

PMID:
10596506
42.

Cognitive-behavioral group treatments in childhood anxiety disorders: the role of parental involvement.

Mendlowitz SL, Manassis K, Bradley S, Scapillato D, Miezitis S, Shaw BF.

J Am Acad Child Adolesc Psychiatry. 1999 Oct;38(10):1223-9.

PMID:
10517054
43.

The East York Health Needs Study. I: Prevalence of DSM-III-R psychiatric disorder in a sample of Canadian women.

Katz R, Stephen J, Shaw BF, Matthew A, Newman F, Rosenbluth M.

Br J Psychiatry. 1995 Jan;166(1):100-6.

PMID:
7894856
44.

Preemptive analgesia. Clinical evidence of neuroplasticity contributing to postoperative pain.

Katz J, Kavanagh BP, Sandler AN, Nierenberg H, Boylan JF, Friedlander M, Shaw BF.

Anesthesiology. 1992 Sep;77(3):439-46.

PMID:
1519781
45.
46.

Value of the Fear Questionnaire in differentiating agoraphobia and social phobia.

Cox BJ, Swinson RP, Shaw BF.

Br J Psychiatry. 1991 Dec;159:842-5.

PMID:
1790455
47.

Biochemical aspects of bulimia nervosa.

Goldbloom DS, Garfinkel PE, Shaw BF.

J Psychosom Res. 1991;35 Suppl 1:11-22. Review. No abstract available.

PMID:
1674288
48.

Cognitive-behavior therapies for major depression: current status with an emphasis on prophylaxis.

Shaw BF.

Psychiatr J Univ Ott. 1989 Jun;14(2):403-8; discussion 409-12. Review.

PMID:
2668996
49.

The use of treatment manuals in cognitive therapy: experience and issues.

Dobson KS, Shaw BF.

J Consult Clin Psychol. 1988 Oct;56(5):673-80. Review. No abstract available.

PMID:
3057005
50.

Competency judgments in the training and evaluation of psychotherapists.

Shaw BF, Dobson KS.

J Consult Clin Psychol. 1988 Oct;56(5):666-72. Review. No abstract available.

PMID:
3057004

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