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Items: 43


Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.

Meegan JE, Shaver CM, Putz ND, Jesse JJ, Landstreet SR, Lee HNR, Sidorova TN, McNeil JB, Wynn JL, Cheung-Flynn J, Komalavilas P, Brophy CM, Ware LB, Bastarache JA.

PLoS One. 2020 Feb 3;15(2):e0228727. doi: 10.1371/journal.pone.0228727. eCollection 2020.


Haptoglobin genotype predicts severe acute vaso-occlusive pain episodes in children with sickle cell anemia.

Willen SM, McNeil JB, Rodeghier M, Kerchberger VE, Shaver CM, Bastarache JA, Steinberg MH, DeBaun MR, Ware LB.

Am J Hematol. 2020 Jan 9. doi: 10.1002/ajh.25728. [Epub ahead of print] No abstract available.


Clinical and Genetic Contributors to New-Onset Atrial Fibrillation in Critically Ill Adults.

Kerchberger VE, Huang Y, Koyama T, Shoemaker MB, Darbar D, Bastarache JA, Ware LB, Shaver CM.

Crit Care Med. 2020 Jan;48(1):22-30. doi: 10.1097/CCM.0000000000004034.


Haptoglobin-2 variant increases susceptibility to acute respiratory distress syndrome during sepsis.

Kerchberger VE, Bastarache JA, Shaver CM, Nagata H, McNeil JB, Landstreet SR, Putz ND, Yu WK, Jesse J, Wickersham NE, Sidorova TN, Janz DR, Parikh CR, Siew ED, Ware LB.

JCI Insight. 2019 Nov 1;4(21). pii: 131206. doi: 10.1172/jci.insight.131206.


Cell-free hemoglobin augments acute kidney injury during experimental sepsis.

Shaver CM, Paul MG, Putz ND, Landstreet SR, Kuck JL, Scarfe L, Skrypnyk N, Yang H, Harrison FE, de Caestecker MP, Bastarache JA, Ware LB.

Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F922-F929. doi: 10.1152/ajprenal.00375.2018. Epub 2019 Jul 31.


Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury.

Yu WK, McNeil JB, Wickersham NE, Shaver CM, Bastarache JA, Ware LB.

Crit Care. 2019 Jan 18;23(1):18. doi: 10.1186/s13054-019-2315-y.


Melanoma Within Basal Cell Carcinoma Nests Discovered During Mohs Micrographic Surgery.

Shaver CM, Kolker SE, Bennett RG.

Dermatol Surg. 2019 Nov;45(11):1419-1421. doi: 10.1097/DSS.0000000000001762. No abstract available.


Large pseudoencapsulated subcutaneous angiomyxoma: Surgical management.

Shaver CM, Kolker SE, Bennett RG.

JAAD Case Rep. 2018 Sep 22;4(8):845-847. doi: 10.1016/j.jdcr.2018.07.006. eCollection 2018 Sep. No abstract available.


Long-Term Physical HRQOL Decreases After Single Lung as Compared With Double Lung Transplantation.

Gilmore DM, Grogan EL, Feurer ID, Hoy H, Rega SA, Barnes J, Park R, Staykov M, Via M, Shaver CM, Pinson CW, Lambright ES.

Ann Thorac Surg. 2018 Dec;106(6):1633-1639. doi: 10.1016/j.athoracsur.2018.06.072. Epub 2018 Aug 16.


Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS.

Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB.

Thorax. 2018 Sep;73(9):840-846. doi: 10.1136/thoraxjnl-2017-211280. Epub 2018 Jun 14.


Optimization of oxygenation during ex vivo lung perfusion-Best basic science article in 2017.

Shaver CM, Diamond JM, Schrepfer S, Cantu E.

J Heart Lung Transplant. 2018 Jun;37(6):800-802. doi: 10.1016/j.healun.2018.02.010. Epub 2018 Feb 21. No abstract available.


Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Miller A, Landstreet SR, Kuck JL, Diamond JM, Lederer DJ, Kawut SM, Palmer SM, Wille KM, Weinacker A, Lama VN, Crespo MM, Orens JB, Shah PD, Hage CA, Cantu E 3rd, Porteous MK, Dhillon G, McDyer J, Bastarache JA, Christie JD, Ware LB; Lung Transplant Outcomes Group (LTOG).

JCI Insight. 2018 Jan 25;3(2). pii: 98546. doi: 10.1172/jci.insight.98546. eCollection 2018 Jan 25.


Red patches on a newborn.

Shaver CM, Cusack CA.

Cutis. 2017 Dec;100(6):E11-E12. No abstract available.


GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury.

Putz ND, Shaver CM, Dufu K, Li CM, Xu Q, Hutchaleelaha A, Lehrer-Graiwer J, Majka SM, Ware LB, Bastarache JA.

J Appl Physiol (1985). 2018 Apr 1;124(4):899-905. doi: 10.1152/japplphysiol.00079.2017. Epub 2017 Dec 14.


Novel Method for Noninvasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome.

McNeil JB, Shaver CM, Kerchberger VE, Russell DW, Grove BS, Warren MA, Wickersham NE, Ware LB, McDonald WH, Bastarache JA.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1027-1035. doi: 10.1164/rccm.201707-1474OC.


Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin.

Kuck JL, Bastarache JA, Shaver CM, Fessel JP, Dikalov SI, May JM, Ware LB.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):433-437. doi: 10.1016/j.bbrc.2017.11.058. Epub 2017 Nov 9.


Endothelial glycocalyx degradation is more severe in patients with non-pulmonary sepsis compared to pulmonary sepsis and associates with risk of ARDS and other organ dysfunction.

Murphy LS, Wickersham N, McNeil JB, Shaver CM, May AK, Bastarache JA, Ware LB.

Ann Intensive Care. 2017 Oct 6;7(1):102. doi: 10.1186/s13613-017-0325-y.


Cell-Free Hemoglobin-mediated Increases in Vascular Permeability. A Novel Mechanism of Primary Graft Dysfunction and a New Therapeutic Target.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Sills G, Kuck JL, Janz DR, Bastarache JA, Ware LB.

Ann Am Thorac Soc. 2017 Sep;14(Supplement_3):S251-S252. doi: 10.1513/AnnalsATS.201609-693MG.


Oxygenation Saturation Index Predicts Clinical Outcomes in ARDS.

DesPrez K, McNeil JB, Wang C, Bastarache JA, Shaver CM, Ware LB.

Chest. 2017 Dec;152(6):1151-1158. doi: 10.1016/j.chest.2017.08.002. Epub 2017 Aug 16. Erratum in: Chest. 2018 Mar;153(3):768.


Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part III: Mechanisms: A 2016 Consensus Group Statement of the International Society for Heart and Lung Transplantation.

Gelman AE, Fisher AJ, Huang HJ, Baz MA, Shaver CM, Egan TM, Mulligan MS.

J Heart Lung Transplant. 2017 Oct;36(10):1114-1120. doi: 10.1016/j.healun.2017.07.014. Epub 2017 Jul 24. Review. No abstract available.


Circulating microparticle levels are reduced in patients with ARDS.

Shaver CM, Woods J, Clune JK, Grove BS, Wickersham NE, McNeil JB, Shemancik G, Ware LB, Bastarache JA.

Crit Care. 2017 May 25;21(1):120. doi: 10.1186/s13054-017-1700-7.


Comparison of Posttransplant Dermatologic Diseases by Race.

Chung CL, Nadhan KS, Shaver CM, Ogrich LM, Abdelmalek M, Cusack CA, Malat GE, Pritchett EN, Doyle A.

JAMA Dermatol. 2017 Jun 1;153(6):552-558. doi: 10.1001/jamadermatol.2017.0045. Erratum in: JAMA Dermatol. 2017 Jun 1;153(6):613.


Primary graft dysfunction: pathophysiology to guide new preventive therapies.

Shaver CM, Ware LB.

Expert Rev Respir Med. 2017 Feb;11(2):119-128. doi: 10.1080/17476348.2017.1280398. Epub 2017 Jan 20. Review.


Randomized Trial of Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults.

Janz DR, Semler MW, Lentz RJ, Matthews DT, Assad TR, Norman BC, Keriwala RD, Ferrell BA, Noto MJ, Shaver CM, Richmond BW, Zinggeler Berg J, Rice TW; Facilitating EndotracheaL intubation by Laryngoscopy technique and apneic Oxygenation Within the ICU Investigators and the Pragmatic Critical Care Research Group.

Crit Care Med. 2016 Nov;44(11):1980-1987.


Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS.

Luo L, Shaver CM, Zhao Z, Koyama T, Calfee CS, Bastarache JA, Ware LB.

Chest. 2017 Apr;151(4):755-763. doi: 10.1016/j.chest.2016.09.004. Epub 2016 Sep 20.


Nonmelanoma Skin Cancer in Nonwhite Organ Transplant Recipients.

Pritchett EN, Doyle A, Shaver CM, Miller B, Abdelmalek M, Cusack CA, Malat GE, Chung CL.

JAMA Dermatol. 2016 Dec 1;152(12):1348-1353. doi: 10.1001/jamadermatol.2016.3328.


The authors reply.

Shaver CM, Ware LB.

Crit Care Med. 2016 May;44(5):e307. doi: 10.1097/CCM.0000000000001579. No abstract available.


Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus-infected mice.

Antoniak S, Tatsumi K, Hisada Y, Milner JJ, Neidich SD, Shaver CM, Pawlinski R, Beck MA, Bastarache JA, Mackman N.

J Thromb Haemost. 2016 Jun;14(6):1238-48. doi: 10.1111/jth.13307. Epub 2016 Apr 5. Erratum in: J Thromb Haemost. 2016 Dec;14 (12 ):2565.


Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury.

Shaver CM, Grove BS, Clune JK, Mackman N, Ware LB, Bastarache JA.

Sci Rep. 2016 Feb 29;6:22249. doi: 10.1038/srep22249.


Cell-free hemoglobin: a novel mediator of acute lung injury.

Shaver CM, Upchurch CP, Janz DR, Grove BS, Putz ND, Wickersham NE, Dikalov SI, Ware LB, Bastarache JA.

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15;310(6):L532-41. doi: 10.1152/ajplung.00155.2015. Epub 2016 Jan 15.


Clinical Characteristics and Outcomes Are Similar in ARDS Diagnosed by Oxygen Saturation/Fio2 Ratio Compared With Pao2/Fio2 Ratio.

Chen W, Janz DR, Shaver CM, Bernard GR, Bastarache JA, Ware LB.

Chest. 2015 Dec;148(6):1477-1483. doi: 10.1378/chest.15-0169.


Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients.

Shaver CM, Chen W, Janz DR, May AK, Darbar D, Bernard GR, Bastarache JA, Ware LB.

Crit Care Med. 2015 Oct;43(10):2104-11. doi: 10.1097/CCM.0000000000001166.


Kinetics of lung tissue factor expression and procoagulant activity in bleomycin induced acute lung injury.

Ma L, Shaver CM, Grove BS, Mitchell DB, Wickersham NE, Carnahan RH, Cooper TL, Brake BE, Ware LB, Bastarache JA.

Clin Transl Med. 2015 Dec;4(1):63. doi: 10.1186/s40169-015-0063-4. Epub 2015 Jun 21.


Regulation of alveolar procoagulant activity and permeability in direct acute lung injury by lung epithelial tissue factor.

Shaver CM, Grove BS, Putz ND, Clune JK, Lawson WE, Carnahan RH, Mackman N, Ware LB, Bastarache JA.

Am J Respir Cell Mol Biol. 2015 Nov;53(5):719-27. doi: 10.1165/rcmb.2014-0179OC.


Clinical and biological heterogeneity in acute respiratory distress syndrome: direct versus indirect lung injury.

Shaver CM, Bastarache JA.

Clin Chest Med. 2014 Dec;35(4):639-53. doi: 10.1016/j.ccm.2014.08.004. Epub 2014 Sep 23. Review.


Fatal Scopulariopsis infection in a lung transplant recipient: lessons of organ procurement.

Shaver CM, Castilho JL, Cohen DN, Grogan EL, Miller GG, Dummer JS, Gray JN, Lambright ES, Loyd JE, Robbins IM.

Am J Transplant. 2014 Dec;14(12):2893-7. doi: 10.1111/ajt.12940. Epub 2014 Nov 6.


Doxycycline desensitization for a suspected case of ehrlichiosis.

Stollings JL, Chadha SN, Paul AM, Shaver CM, Hagaman D.

J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):103-4. doi: 10.1016/j.jaip.2013.08.002. Epub 2013 Sep 25. No abstract available.


Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.

Perentes JY, Kirkpatrick ND, Nagano S, Smith EY, Shaver CM, Sgroi D, Garkavtsev I, Munn LL, Jain RK, Boucher Y.

Cancer Res. 2011 Jul 1;71(13):4527-38. doi: 10.1158/0008-5472.CAN-10-4376. Epub 2011 May 13.


Pseudomonas aeruginosa induces localized immunosuppression during pneumonia.

Diaz MH, Shaver CM, King JD, Musunuri S, Kazzaz JA, Hauser AR.

Infect Immun. 2008 Oct;76(10):4414-21. doi: 10.1128/IAI.00012-08. Epub 2008 Jul 28.


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