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Items: 1 to 50 of 114

1.

Glucosamine reduces the inhibition of proteoglycan metabolism caused by local anaesthetic solution in human articular cartilage: an in vitro study.

Gulihar A, Shaunak S, Novak PL, Vinayakam P, Dhinsa B, Taylor G.

J Exp Orthop. 2017 Nov 13;4(1):37. doi: 10.1186/s40634-017-0106-4.

2.

Advances in 3D Modeling: Preoperative Templating for Revision Wrist Surgery.

Osagie L, Shaunak S, Murtaza A, Cerovac S, Umarji S.

Hand (N Y). 2017 Sep;12(5):NP68-NP72. doi: 10.1177/1558944716681973. Epub 2016 Nov 29.

PMID:
28832216
3.

Cytotoxicity of polycations: Relationship of molecular weight and the hydrolytic theory of the mechanism of toxicity.

Monnery BD, Wright M, Cavill R, Hoogenboom R, Shaunak S, Steinke JH, Thanou M.

Int J Pharm. 2017 Apr 15;521(1-2):249-258. doi: 10.1016/j.ijpharm.2017.02.048. Epub 2017 Feb 21.

PMID:
28232268
4.

Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus during Macrophage Cell Death.

Shah A, Kannambath S, Herbst S, Rogers A, Soresi S, Carby M, Reed A, Mostowy S, Fisher MC, Shaunak S, Armstrong-James DP.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1127-1139.

5.

The Role of 3D Modelling and Printing in Orthopaedic Tissue Engineering: A Review of the Current Literature.

Shaunak S, Dhinsa BS, Khan WS.

Curr Stem Cell Res Ther. 2017;12(3):225-232. doi: 10.2174/1574888X11666160429122238. Review.

PMID:
27133084
6.

Alternatives to antibiotics-a pipeline portfolio review.

Czaplewski L, Bax R, Clokie M, Dawson M, Fairhead H, Fischetti VA, Foster S, Gilmore BF, Hancock RE, Harper D, Henderson IR, Hilpert K, Jones BV, Kadioglu A, Knowles D, Ólafsdóttir S, Payne D, Projan S, Shaunak S, Silverman J, Thomas CM, Trust TJ, Warn P, Rex JH.

Lancet Infect Dis. 2016 Feb;16(2):239-51. doi: 10.1016/S1473-3099(15)00466-1. Epub 2016 Jan 13. Review.

PMID:
26795692
7.

Controlling the cytokine storm in severe bacterial diarrhoea with an oral Toll-like receptor 4 antagonist.

Islam D, Lombardini E, Ruamsap N, Imerbsin R, Khantapura P, Teo I, Neesanant P, Gonwong S, Yongvanitchit K, Swierczewski BE, Mason CJ, Shaunak S.

Immunology. 2016 Feb;147(2):178-89. doi: 10.1111/imm.12549. Epub 2015 Nov 24.

8.

Three-dimensional printing in surgery: a review of current surgical applications.

Malik HH, Darwood AR, Shaunak S, Kulatilake P, El-Hilly AA, Mulki O, Baskaradas A.

J Surg Res. 2015 Dec;199(2):512-22. doi: 10.1016/j.jss.2015.06.051. Epub 2015 Jun 26. Review.

PMID:
26255224
9.

Perspective: Dendrimer drugs for infection and inflammation.

Shaunak S.

Biochem Biophys Res Commun. 2015 Dec 18;468(3):435-41. doi: 10.1016/j.bbrc.2015.07.033. Epub 2015 Jul 10. Review.

PMID:
26168733
10.

Nebulised amphotericin B-polymethacrylic acid nanoparticle prophylaxis prevents invasive aspergillosis.

Shirkhani K, Teo I, Armstrong-James D, Shaunak S.

Nanomedicine. 2015 Jul;11(5):1217-26. doi: 10.1016/j.nano.2015.02.012. Epub 2015 Mar 16.

11.

Systemic cytokine storm in severe eosinophilic dermatitis.

Singanayagam A, Lamb L, Makinde JE, Teo I, Shaunak S.

QJM. 2015 Nov;108(11):907-8. doi: 10.1093/qjmed/hcv056. Epub 2015 Feb 28. No abstract available.

PMID:
25725251
12.

Fulminant acephalgic giant cell arteritis with basal cerebral artery occlusion: A radiological and clinico-pathological study.

Chhetri SK, Bindman D, Joseph J, Mathur S, Shaunak S.

Cephalalgia. 2015 Oct;35(12):1133-6. doi: 10.1177/0333102415570345. Epub 2015 Feb 4. No abstract available.

PMID:
25653307
13.

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell MA, Saijo S, Mostowy S, Shaunak S, Armstrong-James D.

EMBO Mol Med. 2015 Mar;7(3):240-58. doi: 10.15252/emmm.201404556.

14.

Copper deficiency.

Chhetri SK, Mills RJ, Shaunak S, Emsley HC.

BMJ. 2014 Jun 17;348:g3691. doi: 10.1136/bmj.g3691. No abstract available.

PMID:
24938531
15.

Successful laparoscopic removal of an ingested toothbrush.

Jamal K, Shaunak S, Kalsi S, Nehra D.

J Surg Tech Case Rep. 2013 Jul;5(2):99-102. doi: 10.4103/2006-8808.128751.

16.

Clinical assessment of the sensory ataxias; diagnostic algorithm with illustrative cases.

Chhetri SK, Gow D, Shaunak S, Varma A.

Pract Neurol. 2014 Aug;14(4):242-51. doi: 10.1136/practneurol-2013-000764. Epub 2014 Feb 25. Review.

PMID:
24570476
17.

A novel technique for modified onlay incisional hernia repair with mesh incorporation into the fascial defect: a method for addressing suture line failure.

Jamal K, Ratnasingham K, Shaunak S, Ravindran K, Nehra D.

Hernia. 2015 Jun;19(3):473-7. doi: 10.1007/s10029-013-1195-3. Epub 2013 Dec 19.

PMID:
24352638
18.

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF; Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC), Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Søndergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelčić I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL.

Nat Genet. 2013 Nov;45(11):1353-60. doi: 10.1038/ng.2770. Epub 2013 Sep 29.

19.

Secondary aorto-enteric fistula presenting over a 2-month period with recurrent gastrointestinal bleeding.

Jamal K, Shaunak S, Kalsi S, Nehra D.

BMJ Case Rep. 2013 Apr 15;2013. pii: bcr2012008070. doi: 10.1136/bcr-2012-008070.

20.

A new and clinically relevant murine model of solid-organ transplant aspergillosis.

Herbst S, Shah A, Carby M, Chusney G, Kikkeri N, Dorling A, Bignell E, Shaunak S, Armstrong-James D.

Dis Model Mech. 2013 May;6(3):643-51. doi: 10.1242/dmm.010330. Epub 2012 Dec 20.

21.

Renal allograft recipients fail to increase interferon-γ during invasive fungal diseases.

Armstrong-James D, Teo I, Herbst S, Petrou M, Shiu KY, McLean A, Taube D, Dorling A, Shaunak S.

Am J Transplant. 2012 Dec;12(12):3437-40. doi: 10.1111/j.1600-6143.2012.04254.x. Epub 2012 Sep 13.

22.

The role of working memory and attentional disengagement on inhibitory control: effects of aging and Alzheimer's disease.

Crawford TJ, Higham S, Mayes J, Dale M, Shaunak S, Lekwuwa G.

Age (Dordr). 2013 Oct;35(5):1637-50. doi: 10.1007/s11357-012-9466-y. Epub 2012 Aug 18.

23.

Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers.

Teo I, Toms SM, Marteyn B, Barata TS, Simpson P, Johnston KA, Schnupf P, Puhar A, Bell T, Tang C, Zloh M, Matthews S, Rendle PM, Sansonetti PJ, Shaunak S.

EMBO Mol Med. 2012 Sep;4(9):866-81. doi: 10.1002/emmm.201201290. Epub 2012 Aug 6.

24.

Sporadic Creutzfeldt-Jakob disease presenting as progressive nonfluent aphasia with speech apraxia.

Kobylecki C, Thompson JC, Jones M, Mills SJ, Shaunak S, Ironside JW, Snowden JS, Richardson AM.

Alzheimer Dis Assoc Disord. 2013 Oct-Dec;27(4):384-6. doi: 10.1097/WAD.0b013e318260ab27.

PMID:
22732678
25.

Doctors taking a pulse using their mobile phone can spread MRSA.

Morris TC, Moore LS, Shaunak S.

BMJ. 2012 Jan 17;344:e412. doi: 10.1136/bmj.e412. No abstract available.

PMID:
22252697
26.

Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex.

Barata T, Teo I, Lalwani S, Simanek E, Zloh M, Shaunak S.

Biomaterials. 2011 Nov;32(33):8702-11. doi: 10.1016/j.biomaterials.2011.07.085. Epub 2011 Aug 23.

27.

Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid.

Corware K, Harris D, Teo I, Rogers M, Naresh K, Müller I, Shaunak S.

Biomaterials. 2011 Nov;32(31):8029-39. doi: 10.1016/j.biomaterials.2011.07.021. Epub 2011 Jul 31.

28.

Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses.

Barata TS, Teo I, Brocchini S, Zloh M, Shaunak S.

PLoS Comput Biol. 2011 Jun;7(6):e1002095. doi: 10.1371/journal.pcbi.1002095. Epub 2011 Jun 30.

29.

From sequence to 3D structure of hyperbranched molecules: application to surface modified PAMAM dendrimers.

Barata TS, Brocchini S, Teo I, Shaunak S, Zloh M.

J Mol Model. 2011 Nov;17(11):2741-9. doi: 10.1007/s00894-011-0966-y. Epub 2011 Jan 29.

PMID:
21279526
30.

Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers.

Barata TS, Shaunak S, Teo I, Zloh M, Brocchini S.

J Mol Model. 2011 Aug;17(8):2051-60. doi: 10.1007/s00894-010-0907-1. Epub 2010 Dec 15.

PMID:
21161557
31.

A treatable cause for a painful movement disorder.

Paling D, Irfan M, Jones S, Shaunak S.

Pract Neurol. 2010 Dec;10(6):351-4. doi: 10.1136/jnnp.2010.230490. No abstract available.

PMID:
21097834
32.

An amphotericin B-based drug for treating experimental Leishmania major infection.

Corware KD, Rogers M, Teo I, Müller I, Shaunak S.

Trans R Soc Trop Med Hyg. 2010 Nov;104(11):749-50. doi: 10.1016/j.trstmh.2010.08.010. Epub 2010 Sep 17.

33.

Mimicking PAMAM Dendrimers with Ampholytic, Hybrid Triazine Dendrimers: A Comparison of Dispersity and Stability.

Lalwani S, Chouai A, Perez LM, Santiago V, Shaunak S, Simanek EE.

Macromolecules. 2009 Aug 12;42(17):6723-3732.

34.

Wound Healing Versus Regeneration: Role of the Tissue Environment in Regenerative Medicine.

Atala A, Irvine DJ, Moses M, Shaunak S.

MRS Bull. 2010 Aug 1;35(8). doi: 10.1557/mrs2010.528.

35.

Exogenous interferon-gamma immunotherapy for invasive fungal infections in kidney transplant patients.

Armstrong-James D, Teo IA, Shrivastava S, Petrou MA, Taube D, Dorling A, Shaunak S.

Am J Transplant. 2010 Aug;10(8):1796-803. doi: 10.1111/j.1600-6143.2010.03094.x. Epub 2010 Mar 26.

36.

Electrophoretic Behavior of Anionic Triazine and PAMAM Dendrimers: Methods for Improving Resolution and Assessing Purity Using Capillary Electrophoresis.

Lalwani S, Venditto VJ, Chouai A, Rivera GE, Shaunak S, Simanek EE.

Macromolecules. 2009 Apr 28;42(8):3152-3161.

37.

Treatment of refractory neurosarcoidosis with Infliximab.

Santos E, Shaunak S, Renowden S, Scolding NJ.

J Neurol Neurosurg Psychiatry. 2010 Mar;81(3):241-6. doi: 10.1136/jnnp.2008.149989. Epub 2008 Oct 31.

PMID:
18977810
38.

Leber's hereditary optic neuropathy associated with multiple sclerosis: Harding's syndrome.

Parry-Jones AR, Mitchell JD, Gunarwardena WJ, Shaunak S.

Pract Neurol. 2008 Apr;8(2):118-21. doi: 10.1136/jnnp.2007.139360.

PMID:
18344382
39.

Disulfide bridge based PEGylation of proteins.

Brocchini S, Godwin A, Balan S, Choi JW, Zloh M, Shaunak S.

Adv Drug Deliv Rev. 2008 Jan 3;60(1):3-12. Epub 2007 Aug 17. Review.

PMID:
17920720
40.

Identification and insertion of 3-carbon bridges in protein disulfide bonds: a computational approach.

Zloh M, Shaunak S, Balan S, Brocchini S.

Nat Protoc. 2007;2(5):1070-83.

PMID:
17545999
41.

Refractory neurosarcoidosis responsive to infliximab.

Kobylecki C, Shaunak S.

Pract Neurol. 2007 Apr;7(2):112-5. No abstract available.

PMID:
17430876
42.

PEGylation of native disulfide bonds in proteins.

Brocchini S, Balan S, Godwin A, Choi JW, Zloh M, Shaunak S.

Nat Protoc. 2006;1(5):2241-52.

PMID:
17406463
43.

Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge.

Balan S, Choi JW, Godwin A, Teo I, Laborde CM, Heidelberger S, Zloh M, Shaunak S, Brocchini S.

Bioconjug Chem. 2007 Jan-Feb;18(1):61-76.

PMID:
17226958
44.

No change to HIV-1 latency with valproate therapy.

Steel A, Clark S, Teo I, Shaunak S, Nelson M, Gazzard B, Kelleher P.

AIDS. 2006 Aug 1;20(12):1681-2. No abstract available.

PMID:
16868456
45.

Site-specific PEGylation of native disulfide bonds in therapeutic proteins.

Shaunak S, Godwin A, Choi JW, Balan S, Pedone E, Vijayarangam D, Heidelberger S, Teo I, Zloh M, Brocchini S.

Nat Chem Biol. 2006 Jun;2(6):312-3. Epub 2006 Apr 23.

PMID:
16633351
46.

Dendrimer-based drugs as macromolecular medicines.

Shaunak S, Brocchini S.

Biotechnol Genet Eng Rev. 2006;23:309-15. Review. No abstract available.

PMID:
22530514
47.
48.

Short communication: pitfalls of culturing C8166 cells in serum-free media.

Teo I, Choi JW, Buttigieg K, Shaunak S.

AIDS Res Hum Retroviruses. 2005 Mar;21(3):246-8.

PMID:
15795532
49.

Dendrimer drugs prevent scar tissue formation.

Shaunak S.

Discov Med. 2004 Dec;4(24):464-9.

50.

Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation.

Shaunak S, Thomas S, Gianasi E, Godwin A, Jones E, Teo I, Mireskandari K, Luthert P, Duncan R, Patterson S, Khaw P, Brocchini S.

Nat Biotechnol. 2004 Aug;22(8):977-84. Epub 2004 Jul 18.

PMID:
15258595

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