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Items: 1 to 50 of 106

1.

Diversity and Functional Evolution of Terpene Synthases in Dictyostelid Social Amoebae.

Chen X, Köllner TG, Shaulsky G, Jia Q, Dickschat JS, Gershenzon J, Chen F.

Sci Rep. 2018 Sep 25;8(1):14361. doi: 10.1038/s41598-018-32639-0.

2.

De novo mutations in GRIN1 cause extensive bilateral polymicrogyria.

Fry AE, Fawcett KA, Zelnik N, Yuan H, Thompson BAN, Shemer-Meiri L, Cushion TD, Mugalaasi H, Sims D, Stoodley N, Chung SK, Rees MI, Patel CV, Brueton LA, Layet V, Giuliano F, Kerr MP, Banne E, Meiner V, Lerman-Sagie T, Helbig KL, Kofman LH, Knight KM, Chen W, Kannan V, Hu C, Kusumoto H, Zhang J, Swanger SA, Shaulsky GH, Mirzaa GM, Muir AM, Mefford HC, Dobyns WB, Mackenzie AB, Mullins JGL, Lemke JR, Bahi-Buisson N, Traynelis SF, Iago HF, Pilz DT.

Brain. 2018 Jan 22. doi: 10.1093/brain/awx358. [Epub ahead of print]

3.

The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor.

Kaiser TM, Kell SA, Kusumoto H, Shaulsky G, Bhattacharya S, Epplin MP, Strong KL, Miller EJ, Cox BD, Menaldino DS, Liotta DC, Traynelis SF, Burger PB.

Mol Pharmacol. 2018 Feb;93(2):141-156. doi: 10.1124/mol.117.110940. Epub 2017 Dec 14.

PMID:
29242355
4.

Curcumin affects gene expression and reactive oxygen species via a PKA dependent mechanism in Dictyostelium discoideum.

Swatson WS, Katoh-Kurasawa M, Shaulsky G, Alexander S.

PLoS One. 2017 Nov 14;12(11):e0187562. doi: 10.1371/journal.pone.0187562. eCollection 2017.

5.

The polymorphic proteins TgrB1 and TgrC1 function as a ligand-receptor pair in Dictyostelium allorecognition.

Hirose S, Chen G, Kuspa A, Shaulsky G.

J Cell Sci. 2017 Dec 1;130(23):4002-4012. doi: 10.1242/jcs.208975. Epub 2017 Oct 16.

6.

dictyExpress: a web-based platform for sequence data management and analytics in Dictyostelium and beyond.

Stajdohar M, Rosengarten RD, Kokosar J, Jeran L, Blenkus D, Shaulsky G, Zupan B.

BMC Bioinformatics. 2017 Jun 2;18(1):291. doi: 10.1186/s12859-017-1706-9.

7.

A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia.

Gao K, Tankovic A, Zhang Y, Kusumoto H, Zhang J, Chen W, XiangWei W, Shaulsky GH, Hu C, Traynelis SF, Yuan H, Jiang Y.

PLoS One. 2017 Feb 9;12(2):e0170818. doi: 10.1371/journal.pone.0170818. eCollection 2017.

8.

The Long Noncoding RNA Transcriptome of Dictyostelium discoideum Development.

Rosengarten RD, Santhanam B, Kokosar J, Shaulsky G.

G3 (Bethesda). 2017 Feb 9;7(2):387-398. doi: 10.1534/g3.116.037150.

9.

Terpene synthase genes in eukaryotes beyond plants and fungi: Occurrence in social amoebae.

Chen X, Köllner TG, Jia Q, Norris A, Santhanam B, Rabe P, Dickschat JS, Shaulsky G, Gershenzon J, Chen F.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12132-12137. Epub 2016 Oct 7.

10.

Gene discovery by chemical mutagenesis and whole-genome sequencing in Dictyostelium.

Li CL, Santhanam B, Webb AN, Zupan B, Shaulsky G.

Genome Res. 2016 Sep;26(9):1268-76. doi: 10.1101/gr.205682.116. Epub 2016 Jun 15.

11.

The GATA transcription factor gene gtaG is required for terminal differentiation in Dictyostelium.

Katoh-Kurasawa M, Santhanam B, Shaulsky G.

J Cell Sci. 2016 Mar 9. pii: jcs.181545. [Epub ahead of print]

12.

Gene Prioritization by Compressive Data Fusion and Chaining.

Žitnik M, Nam EA, Dinh C, Kuspa A, Shaulsky G, Zupan B.

PLoS Comput Biol. 2015 Oct 14;11(10):e1004552. doi: 10.1371/journal.pcbi.1004552. eCollection 2015 Oct.

13.

Allorecognition, via TgrB1 and TgrC1, mediates the transition from unicellularity to multicellularity in the social amoeba Dictyostelium discoideum.

Hirose S, Santhanam B, Katoh-Kurosawa M, Shaulsky G, Kuspa A.

Development. 2015 Oct 15;142(20):3561-70. doi: 10.1242/dev.123281. Epub 2015 Sep 22.

14.

Altered N-glycosylation modulates TgrB1- and TgrC1-mediated development but not allorecognition in Dictyostelium.

Li CL, Chen G, Webb AN, Shaulsky G.

J Cell Sci. 2015 Nov 1;128(21):3990-6. doi: 10.1242/jcs.172882. Epub 2015 Sep 10.

15.

The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium.

Santhanam B, Cai H, Devreotes PN, Shaulsky G, Katoh-Kurasawa M.

Nat Commun. 2015 Jul 6;6:7551. doi: 10.1038/ncomms8551.

16.

Genomic signatures of cooperation and conflict in the social amoeba.

Ostrowski EA, Shen Y, Tian X, Sucgang R, Jiang H, Qu J, Katoh-Kurasawa M, Brock DA, Dinh C, Lara-Garduno F, Lee SL, Kovar CL, Dinh HH, Korchina V, Jackson L, Patil S, Han Y, Chaboub L, Shaulsky G, Muzny DM, Worley KC, Gibbs RA, Richards S, Kuspa A, Strassmann JE, Queller DC.

Curr Biol. 2015 Jun 15;25(12):1661-5. doi: 10.1016/j.cub.2015.04.059. Epub 2015 Jun 4.

17.

A deep coverage Dictyostelium discoideum genomic DNA library replicates stably in Escherichia coli.

Rosengarten RD, Beltran PR, Shaulsky G.

Genomics. 2015 Oct;106(4):249-55. doi: 10.1016/j.ygeno.2015.05.008. Epub 2015 May 29.

18.

Temporal regulation of kin recognition maintains recognition-cue diversity and suppresses cheating.

Ho HI, Shaulsky G.

Nat Commun. 2015 May 28;6:7144. doi: 10.1038/ncomms8144.

19.

TgrC1 Has Distinct Functions in Dictyostelium Development and Allorecognition.

Wang Y, Shaulsky G.

PLoS One. 2015 Apr 20;10(4):e0124270. doi: 10.1371/journal.pone.0124270. eCollection 2015.

20.

Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum.

Rosengarten RD, Santhanam B, Fuller D, Katoh-Kurasawa M, Loomis WF, Zupan B, Shaulsky G.

BMC Genomics. 2015 Apr 13;16:294. doi: 10.1186/s12864-015-1491-7.

21.

The ABC transporter, AbcB3, mediates cAMP export in D. discoideum development.

Miranda ER, Nam EA, Kuspa A, Shaulsky G.

Dev Biol. 2015 Jan 15;397(2):203-11. doi: 10.1016/j.ydbio.2014.11.006. Epub 2014 Nov 20.

22.

Determination and inference of eukaryotic transcription factor sequence specificity.

Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, Walhout AJM, Bouget FY, Ratsch G, Larrondo LF, Ecker JR, Hughes TR.

Cell. 2014 Sep 11;158(6):1431-1443. doi: 10.1016/j.cell.2014.08.009.

23.

Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.

Cai H, Katoh-Kurasawa M, Muramoto T, Santhanam B, Long Y, Li L, Ueda M, Iglesias PA, Shaulsky G, Devreotes PN.

Science. 2014 Mar 21;343(6177):1249531. doi: 10.1126/science.1249531.

24.

ABC transporters in Dictyostelium discoideum development.

Miranda ER, Zhuchenko O, Toplak M, Santhanam B, Zupan B, Kuspa A, Shaulsky G.

PLoS One. 2013 Aug 14;8(8):e70040. doi: 10.1371/journal.pone.0070040. eCollection 2013.

25.

Kin recognition protects cooperators against cheaters.

Ho HI, Hirose S, Kuspa A, Shaulsky G.

Curr Biol. 2013 Aug 19;23(16):1590-5. doi: 10.1016/j.cub.2013.06.049. Epub 2013 Aug 1.

26.

Bacterial discrimination by dictyostelid amoebae reveals the complexity of ancient interspecies interactions.

Nasser W, Santhanam B, Miranda ER, Parikh A, Juneja K, Rot G, Dinh C, Chen R, Zupan B, Shaulsky G, Kuspa A.

Curr Biol. 2013 May 20;23(10):862-72. doi: 10.1016/j.cub.2013.04.034. Epub 2013 May 9.

27.

Transcriptional profiling of Dictyostelium with RNA sequencing.

Miranda ER, Rot G, Toplak M, Santhanam B, Curk T, Shaulsky G, Zupan B.

Methods Mol Biol. 2013;983:139-71. doi: 10.1007/978-1-62703-302-2_8.

28.

A new social gene in Dictyostelium discoideum, chtB.

Santorelli LA, Kuspa A, Shaulsky G, Queller DC, Strassmann JE.

BMC Evol Biol. 2013 Jan 9;13:4. doi: 10.1186/1471-2148-13-4.

29.

BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium.

Huang E, Talukder S, Hughes TR, Curk T, Zupan B, Shaulsky G, Katoh-Kurasawa M.

Dev Biol. 2011 Oct 1;358(1):137-46. doi: 10.1016/j.ydbio.2011.07.017. Epub 2011 Jul 23.

30.

The putative bZIP transcription factor BzpN slows proliferation and functions in the regulation of cell density by autocrine signals in Dictyostelium.

Phillips JE, Huang E, Shaulsky G, Gomer RH.

PLoS One. 2011;6(7):e21765. doi: 10.1371/journal.pone.0021765. Epub 2011 Jul 7.

31.

Self-recognition in social amoebae is mediated by allelic pairs of tiger genes.

Hirose S, Benabentos R, Ho HI, Kuspa A, Shaulsky G.

Science. 2011 Jul 22;333(6041):467-70. doi: 10.1126/science.1203903. Epub 2011 Jun 23.

32.

Developmental changes in transcriptional profiles.

Loomis WF, Shaulsky G.

Dev Growth Differ. 2011 May;53(4):567-75. doi: 10.1111/j.1440-169X.2010.01241.x. Epub 2011 Mar 30. Review.

PMID:
21447097
33.

Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum.

Sucgang R, Kuo A, Tian X, Salerno W, Parikh A, Feasley CL, Dalin E, Tu H, Huang E, Barry K, Lindquist E, Shapiro H, Bruce D, Schmutz J, Salamov A, Fey P, Gaudet P, Anjard C, Babu MM, Basu S, Bushmanova Y, van der Wel H, Katoh-Kurasawa M, Dinh C, Coutinho PM, Saito T, Elias M, Schaap P, Kay RR, Henrissat B, Eichinger L, Rivero F, Putnam NH, West CM, Loomis WF, Chisholm RL, Shaulsky G, Strassmann JE, Queller DC, Kuspa A, Grigoriev IV.

Genome Biol. 2011;12(2):R20. doi: 10.1186/gb-2011-12-2-r20. Epub 2011 Feb 28.

34.

New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data.

Parikh A, Huang E, Dinh C, Zupan B, Kuspa A, Subramanian D, Shaulsky G.

BMC Bioinformatics. 2010 Mar 31;11:163. doi: 10.1186/1471-2105-11-163.

35.

Conserved developmental transcriptomes in evolutionarily divergent species.

Parikh A, Miranda ER, Katoh-Kurasawa M, Fuller D, Rot G, Zagar L, Curk T, Sucgang R, Chen R, Zupan B, Loomis WF, Kuspa A, Shaulsky G.

Genome Biol. 2010;11(3):R35. doi: 10.1186/gb-2010-11-3-r35. Epub 2010 Mar 17.

36.

Cheating by exploitation of developmental prestalk patterning in Dictyostelium discoideum.

Khare A, Shaulsky G.

PLoS Genet. 2010 Feb 26;6(2):e1000854. doi: 10.1371/journal.pgen.1000854.

37.

Cheater-resistance is not futile.

Khare A, Santorelli LA, Strassmann JE, Queller DC, Kuspa A, Shaulsky G.

Nature. 2009 Oct 15;461(7266):980-2. doi: 10.1038/nature08472. Epub 2009 Sep 30.

PMID:
19794414
38.

dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface.

Rot G, Parikh A, Curk T, Kuspa A, Shaulsky G, Zupan B.

BMC Bioinformatics. 2009 Aug 25;10:265. doi: 10.1186/1471-2105-10-265.

39.

Learning to get along despite struggling to get by.

Ostrowski EA, Shaulsky G.

Genome Biol. 2009;10(5):218. doi: 10.1186/gb-2009-10-5-218. Epub 2009 May 26.

40.

Rule-based clustering for gene promoter structure discovery.

Curk T, Petrovic U, Shaulsky G, Zupan B.

Methods Inf Med. 2009;48(3):229-35. doi: 10.3414/ME9225. Epub 2009 Apr 20.

41.

Polymorphic members of the lag gene family mediate kin discrimination in Dictyostelium.

Benabentos R, Hirose S, Sucgang R, Curk T, Katoh M, Ostrowski EA, Strassmann JE, Queller DC, Zupan B, Shaulsky G, Kuspa A.

Curr Biol. 2009 Apr 14;19(7):567-72. doi: 10.1016/j.cub.2009.02.037. Epub 2009 Mar 12.

42.

Kin discrimination increases with genetic distance in a social amoeba.

Ostrowski EA, Katoh M, Shaulsky G, Queller DC, Strassmann JE.

PLoS Biol. 2008 Nov 25;6(11):e287. doi: 10.1371/journal.pbio.0060287.

43.

dictyBase--a Dictyostelium bioinformatics resource update.

Fey P, Gaudet P, Curk T, Zupan B, Just EM, Basu S, Merchant SN, Bushmanova YA, Shaulsky G, Kibbe WA, Chisholm RL.

Nucleic Acids Res. 2009 Jan;37(Database issue):D515-9. doi: 10.1093/nar/gkn844. Epub 2008 Oct 30.

44.

Facultative cheater mutants reveal the genetic complexity of cooperation in social amoebae.

Santorelli LA, Thompson CR, Villegas E, Svetz J, Dinh C, Parikh A, Sucgang R, Kuspa A, Strassmann JE, Queller DC, Shaulsky G.

Nature. 2008 Feb 28;451(7182):1107-10. doi: 10.1038/nature06558. Epub 2008 Feb 13.

PMID:
18272966
45.

Developmental commitment in Dictyostelium discoideum.

Katoh M, Chen G, Roberge E, Shaulsky G, Kuspa A.

Eukaryot Cell. 2007 Nov;6(11):2038-45. Epub 2007 Sep 28.

46.

Global transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targets.

Van Driessche N, Alexander H, Min J, Kuspa A, Alexander S, Shaulsky G.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15406-11. Epub 2007 Sep 18.

47.

The cold war of the social amoebae.

Shaulsky G, Kessin RH.

Curr Biol. 2007 Aug 21;17(16):R684-92. Review.

48.

MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.

Mendoza MC, Booth EO, Shaulsky G, Firtel RA.

Mol Cell Biol. 2007 May;27(10):3817-27. Epub 2007 Mar 12.

49.

Social evolution: kin preference in a social microbe.

Mehdiabadi NJ, Jack CN, Farnham TT, Platt TG, Kalla SE, Shaulsky G, Queller DC, Strassmann JE.

Nature. 2006 Aug 24;442(7105):881-2.

PMID:
16929288
50.

First among equals: competition between genetically identical cells.

Khare A, Shaulsky G.

Nat Rev Genet. 2006 Jul;7(7):577-83. Epub 2006 May 16. Review.

PMID:
16702983

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