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Items: 1 to 50 of 196

1.

Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening.

Bauman JD, Patel D, Dharia C, Fromer MW, Ahmed S, Frenkel Y, Vijayan RS, Eck JT, Ho WC, Das K, Shatkin AJ, Arnold E.

J Med Chem. 2013 Apr 11;56(7):2738-46. doi: 10.1021/jm301271j. Epub 2013 Feb 20.

2.

Cap and cap-binding proteins in the control of gene expression.

Topisirovic I, Svitkin YV, Sonenberg N, Shatkin AJ.

Wiley Interdiscip Rev RNA. 2011 Mar-Apr;2(2):277-98. doi: 10.1002/wrna.52. Epub 2010 Oct 28. Review.

PMID:
21957010
3.

Structure of the guanylyltransferase domain of human mRNA capping enzyme.

Chu C, Das K, Tyminski JR, Bauman JD, Guan R, Qiu W, Montelione GT, Arnold E, Shatkin AJ.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10104-8. doi: 10.1073/pnas.1106610108. Epub 2011 Jun 2.

4.

Species-specific cis-regulatory elements in the 3'-untranslated region direct alternative polyadenylation of bone morphogenetic protein 2 mRNA.

Liu D, Fritz DT, Rogers MB, Shatkin AJ.

J Biol Chem. 2008 Oct 17;283(42):28010-9. doi: 10.1074/jbc.M804895200. Epub 2008 Aug 14.

5.

Apoptosis and autophagy induction in mammalian cells by small interfering RNA knockdown of mRNA capping enzymes.

Chu C, Shatkin AJ.

Mol Cell Biol. 2008 Oct;28(19):5829-36. doi: 10.1128/MCB.00021-08. Epub 2008 Aug 4.

6.

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.

Bauman JD, Das K, Ho WC, Baweja M, Himmel DM, Clark AD Jr, Oren DA, Boyer PL, Hughes SH, Shatkin AJ, Arnold E.

Nucleic Acids Res. 2008 Sep;36(15):5083-92. doi: 10.1093/nar/gkn464. Epub 2008 Aug 1.

7.

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.

Das K, Bauman JD, Clark AD Jr, Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1466-71. doi: 10.1073/pnas.0711209105. Epub 2008 Jan 29.

8.

Human capping enzyme promotes formation of transcriptional R loops in vitro.

Kaneko S, Chu C, Shatkin AJ, Manley JL.

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17620-5. Epub 2007 Oct 31.

10.

Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II.

Mandal SS, Chu C, Wada T, Handa H, Shatkin AJ, Reinberg D.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7572-7. Epub 2004 May 10.

11.

The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA.

Zhou M, Deng L, Kashanchi F, Brady JN, Shatkin AJ, Kumar A.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12666-71. Epub 2003 Oct 20.

12.

mRNA capping enzyme requirement for Caenorhabditis elegans viability.

Srinivasan P, Piano F, Shatkin AJ.

J Biol Chem. 2003 Apr 18;278(16):14168-73. Epub 2003 Feb 7.

13.
14.

Viral and cellular mRNA capping: past and prospects.

Furuichi Y, Shatkin AJ.

Adv Virus Res. 2000;55:135-84. Review. No abstract available.

PMID:
11050942
15.

The ends of the affair: capping and polyadenylation.

Shatkin AJ, Manley JL.

Nat Struct Biol. 2000 Oct;7(10):838-42. Review.

PMID:
11017188
16.

Transcription elongation factor hSPT5 stimulates mRNA capping.

Wen Y, Shatkin AJ.

Genes Dev. 1999 Jul 15;13(14):1774-9.

17.

Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR.

Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ.

Genomics. 1999 Mar 1;56(2):217-20.

PMID:
10051408
18.

Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively.

Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ.

Genomics. 1998 Dec 1;54(2):351-3. No abstract available.

PMID:
9828141
19.

Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism.

Wen Y, Yue Z, Shatkin AJ.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12226-31.

20.

Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.

Pillutla RC, Yue Z, Maldonado E, Shatkin AJ.

J Biol Chem. 1998 Aug 21;273(34):21443-6.

21.

Enzymatic and control functions of reovirus structural proteins.

Yue Z, Shatkin AJ.

Curr Top Microbiol Immunol. 1998;233(Pt 1):31-56. Review. No abstract available.

PMID:
9599920
22.

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II.

Yue Z, Maldonado E, Pillutla R, Cho H, Reinberg D, Shatkin AJ.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12898-903.

23.
27.
28.

A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII.

Yeh CH, Shatkin AJ.

Gene. 1994 Jun 10;143(2):285-7.

PMID:
8206389
29.
30.

Getting a piece of the action.

Feldman J, Shatkin AJ.

R I Dent J. 1993 SPR;26(1):3. No abstract available.

PMID:
8362166
32.

Site-directed mutants of Escherichia coli alpha-ketoglutarate permease (KgtP).

Seol W, Shatkin AJ.

Biochemistry. 1992 Apr 7;31(13):3550-4.

PMID:
1554735
34.
35.

Translational effects and sequence comparisons of the three serotypes of the reovirus S4 gene.

Seliger LS, Giantini M, Shatkin AJ.

Virology. 1992 Mar;187(1):202-10.

PMID:
1736524
36.

Bruxism and bruxomania.

Shatkin AJ.

R I Dent J. 1992 Winter;25(4):7-10. No abstract available.

PMID:
1306911
37.

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter.

Seol W, Shatkin AJ.

Proc Natl Acad Sci U S A. 1991 May 1;88(9):3802-6. Erratum in: Proc Natl Acad Sci U S A 1991 Jun 15;88(12):5477.

38.

A new gene located between pss and rrnG on the Escherichia coli chromosome.

Seol W, Shatkin AJ.

J Bacteriol. 1990 Sep;172(9):4745. No abstract available.

39.

Expression of the two reovirus S1 gene products in transfected mammalian cells.

Fajardo E, Shatkin AJ.

Virology. 1990 Sep;178(1):223-31.

PMID:
2117829
40.

Sequence of the distal end of E. coli ribosomal RNA rrnG operon.

Seol W, Shatkin AJ.

Nucleic Acids Res. 1990 May 25;18(10):3056. No abstract available.

41.

Active site localization in a viral mRNA capping enzyme.

Fausnaugh J, Shatkin AJ.

J Biol Chem. 1990 May 5;265(13):7669-72.

42.
43.

Effects of elongation on the translation of a reovirus bicistronic mRNA.

Fajardo JE, Shatkin AJ.

Enzyme. 1990;44(1-4):235-43.

PMID:
1966840
45.

Characterization of cap structures.

Furuichi Y, Shatkin AJ.

Methods Enzymol. 1989;180:164-76. No abstract available.

PMID:
2693907
46.
47.
48.

mRNA caps--old and newer hats.

Shatkin AJ.

Bioessays. 1987 Dec;7(6):275-7. Review. No abstract available.

PMID:
3325057
49.

Direct reimbursement: a winning concept.

Shatkin AJ.

R I Dent J. 1987 Spring;20(1):12, 14-5. No abstract available.

PMID:
3472303
50.

Reovirus major capsid protein expressed in Escherichia coli.

Giantini M, Shatkin AJ.

Gene. 1987;56(1):153-60.

PMID:
3315858

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