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Items: 1 to 50 of 157

1.

Pillars Article: Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells. Immunity. 2000. 13: 59-71.

Brugnera E, Bhandoola A, Cibotti R, Yu Q, Guinter TI, Yamashita Y, Sharrow SO, Singer A.

J Immunol. 2016 Mar 1;196(5):1985-97. No abstract available.

2.

Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.

Pobezinsky LA, Etzensperger R, Jeurling S, Alag A, Kadakia T, McCaughtry TM, Kimura MY, Sharrow SO, Guinter TI, Feigenbaum L, Singer A.

Nat Immunol. 2015 May;16(5):517-24. doi: 10.1038/ni.3146. Epub 2015 Apr 6.

3.

T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction.

Fujihara C, Williams JA, Watanabe M, Jeon H, Sharrow SO, Hodes RJ.

J Immunol. 2014 Dec 1;193(11):5534-44. doi: 10.4049/jimmunol.1401655. Epub 2014 Oct 24.

4.

Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.

Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ.

J Immunol. 2014 Jan 15;192(2):630-40. doi: 10.4049/jimmunol.1302550. Epub 2013 Dec 13.

5.

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.

Van Laethem F, Tikhonova AN, Pobezinsky LA, Tai X, Kimura MY, Le Saout C, Guinter TI, Adams A, Sharrow SO, Bernhardt G, Feigenbaum L, Singer A.

Cell. 2013 Sep 12;154(6):1326-41. doi: 10.1016/j.cell.2013.08.009.

6.

Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells.

Tai X, Van Laethem F, Pobezinsky L, Guinter T, Sharrow SO, Adams A, Granger L, Kruhlak M, Lindsten T, Thompson CB, Feigenbaum L, Singer A.

Blood. 2012 May 31;119(22):5155-63. doi: 10.1182/blood-2011-11-388918. Epub 2012 Mar 7.

7.

Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.

Sarafova SD, Van Laethem F, Adoro S, Guinter T, Sharrow SO, Feigenbaum L, Singer A.

Immunity. 2009 Sep 18;31(3):480-90. doi: 10.1016/j.immuni.2009.07.006. Epub 2009 Sep 10.

8.

Analysis of flow cytometry data.

Sharrow SO.

Curr Protoc Immunol. 2001 May;Chapter 5:Unit 5.2. doi: 10.1002/0471142735.im0502s00.

PMID:
18668699
9.

Overview of flow cytometry.

Sharrow SO.

Curr Protoc Immunol. 2002 Nov;Chapter 5:Unit 5.1. doi: 10.1002/0471142735.im0501s50.

PMID:
18432884
10.

Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

Van Laethem F, Sarafova SD, Park JH, Tai X, Pobezinsky L, Guinter TI, Adoro S, Adams A, Sharrow SO, Feigenbaum L, Singer A.

Immunity. 2007 Nov;27(5):735-50.

11.

Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A.

J Immunol. 2006 Nov 15;177(10):6613-25.

12.

Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

Sarafova SD, Erman B, Yu Q, Van Laethem F, Guinter T, Sharrow SO, Feigenbaum L, Wildt KF, Ellmeier W, Singer A.

Immunity. 2005 Jul;23(1):75-87.

13.

A dose effect of IL-7 on thymocyte development.

El Kassar N, Lucas PJ, Klug DB, Zamisch M, Merchant M, Bare CV, Choudhury B, Sharrow SO, Richie E, Mackall CL, Gress RE.

Blood. 2004 Sep 1;104(5):1419-27. Epub 2004 May 20.

14.

Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function.

Chu YW, Memon SA, Sharrow SO, Hakim FT, Eckhaus M, Lucas PJ, Gress RE.

Blood. 2004 Aug 15;104(4):1110-9. Epub 2004 May 6.

16.
17.

CD40 ligand functions non-cell autonomously to promote deletion of self-reactive thymocytes.

Williams JA, Sharrow SO, Adams AJ, Hodes RJ.

J Immunol. 2002 Mar 15;168(6):2759-65.

18.
19.
20.

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells.

Brugnera E, Bhandoola A, Cibotti R, Yu Q, Guinter TI, Yamashita Y, Sharrow SO, Singer A.

Immunity. 2000 Jul;13(1):59-71.

22.

Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment.

Bhandoola A, Cibotti R, Punt JA, Granger L, Adams AJ, Sharrow SO, Singer A.

Immunity. 1999 Mar;10(3):301-11.

23.

Developmentally regulated expression of peanut agglutinin (PNA)-specific glycans on murine thymocytes.

Wu W, Punt JA, Granger L, Sharrow SO, Kearse KP.

Glycobiology. 1997 Apr;7(3):349-56.

PMID:
9147043
24.
26.

Identification of CD8 as a peanut agglutinin (PNA) receptor molecule on immature thymocytes.

Wu W, Harley PH, Punt JA, Sharrow SO, Kearse KP.

J Exp Med. 1996 Aug 1;184(2):759-64.

27.
29.

Programmed differentiation of murine thymocytes during fetal thymus organ culture.

DeLuca D, Bluestone JA, Shultz LD, Sharrow SO, Tatsumi Y.

J Immunol Methods. 1995 Jan 13;178(1):13-29.

PMID:
7829862
31.

Engagement of the external domains of CD45 tyrosine phosphatase can regulate the differentiation of immature CD4+CD8+ thymocytes into mature T cells.

Benveniste P, Takahama Y, Wiest DL, Nakayama T, Sharrow SO, Singer A.

Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):6933-7.

32.

Quantitative differences in cell surface expression of class I MHC antigens on murine epidermal Langerhans cells.

Sharrow SO, Barden LA, Singer A, Katz SI.

J Immunol. 1994 Jul 1;153(1):110-6.

PMID:
8207229
33.

Expression of the homotypic adhesion molecule E-cadherin by immature murine thymocytes and thymic epithelial cells.

Lee MG, Sharrow SO, Farr AG, Singer A, Udey MC.

J Immunol. 1994 Jun 15;152(12):5653-9.

PMID:
8207198
34.
35.

Murine dendritic epidermal T cells (DETC) express the homophilic adhesion molecule E-cadherin.

Lee MG, Tang A, Sharrow SO, Udey MC.

Epithelial Cell Biol. 1994;3(4):149-55.

PMID:
7550606
36.

T cell receptor V alpha-V beta combinatorial selection in the expressed T cell repertoire.

Vacchio MS, Granger L, Kanagawa O, Malissen B, Tomonari K, Sharrow SO, Hodes RJ.

J Immunol. 1993 Aug 1;151(3):1322-7.

PMID:
8101542
37.

Antigenic heterogeneity of Qa-2 antigens in C57BL/6.

Park E, Shinohara N, Arn JS, Sharrow SO, Waneck GL, Sacks DH.

Microbiol Immunol. 1993;37(9):743-52.

38.

Differential expression of VLA-alpha 4 and VLA-beta 1 discriminates multiple subsets of CD4+CD45R0+ "memory" T cells.

Horgan KJ, Luce GE, Tanaka Y, Schweighoffer T, Shimizu Y, Sharrow SO, Shaw S.

J Immunol. 1992 Dec 15;149(12):4082-7.

PMID:
1360997
39.

Dichotomy of glutathione regulation of the activation of resting and preactivated lymphocytes.

Ting CC, Hargrove ME, Liang SM, Liang CM, Sharrow SO.

Cell Immunol. 1992 Jun;142(1):40-53.

PMID:
1534039
40.

Monoclonal antibodies against human T cell adhesion molecules--modulation of immune function in nonhuman primates.

Berlin PJ, Bacher JD, Sharrow SO, Gonzalez C, Gress RE.

Transplantation. 1992 Apr;53(4):840-9.

PMID:
1348883
41.

Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations.

Hathcock KS, Laszlo G, Dickler HB, Sharrow SO, Johnson P, Trowbridge IS, Hodes RJ.

J Immunol. 1992 Jan 1;148(1):19-28.

PMID:
1370168
43.
46.

Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4.

Nakayama T, June CH, Munitz TI, Sheard M, McCarthy SA, Sharrow SO, Samelson LE, Singer A.

Science. 1990 Sep 28;249(4976):1558-61.

PMID:
2120773
47.
48.

T cell receptor-negative thymocytes from SCID mice can be induced to enter the CD4/CD8 differentiation pathway.

Shores EW, Sharrow SO, Uppenkamp I, Singer A.

Eur J Immunol. 1990 Jan;20(1):69-77.

PMID:
1968394
49.

Failure of T cell receptor V beta negative selection in an athymic environment.

Hodes RJ, Sharrow SO, Solomon A.

Science. 1989 Nov 24;246(4933):1041-4.

PMID:
2587987
50.

Effect of cyclosporin A on lymphopoiesis. II. Developmental defects of immature and mature thymocytes in fetal thymus organ cultures treated with cyclosporin A.

Kosugi A, Zuniga-Pflucker JC, Sharrow SO, Kruisbeek AM, Shearer GM.

J Immunol. 1989 Nov 15;143(10):3134-40.

PMID:
2809194

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