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Positive charge patterning and hydrophobicity of membrane-active antimicrobial peptides as determinants of activity, toxicity, and pharmacokinetic stability.

Stone TA, Cole GB, Ravamehr-Lake D, Nguyen HQ, Khan F, Sharpe S, Deber CM.

J Med Chem. 2019 Jun 13. doi: 10.1021/acs.jmedchem.9b00657. [Epub ahead of print]


Hawthorne effect in the YourCall trial suggested by participants' qualitative responses.

Sharpe S, Kool B, Whittaker R, Ameratunga S.

J Clin Epidemiol. 2019 Jun 3. pii: S0895-4356(19)30305-1. doi: 10.1016/j.jclinepi.2019.05.035. [Epub ahead of print] No abstract available.


Effect of a text message intervention on alcohol-related harms and behaviours: secondary outcomes of a randomised controlled trial.

Sharpe S, Kool B, Whittaker R, Lee AC, Reid P, Civil I, Ameratunga S.

BMC Res Notes. 2019 May 14;12(1):267. doi: 10.1186/s13104-019-4308-y.


Genome Organization of Canada Goose Coronavirus, A Novel Species Identified in a Mass Die-off of Canada Geese.

Papineau A, Berhane Y, Wylie TN, Wylie KM, Sharpe S, Lung O.

Sci Rep. 2019 Apr 11;9(1):5954. doi: 10.1038/s41598-019-42355-y.


Author Correction: The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2019 Apr 3;9(1):5596. doi: 10.1038/s41598-019-41387-8.


Emergence of Neisseria gonorrhoeae Strains Harboring a Novel Combination of Azithromycin-Attenuating Mutations.

Pham CD, Sharpe S, Schlanger K, St Cyr S, Holderman J, Steece R, Soge OO, Masinde G, Arno J, Schmerer M, Kersh EN; SURRG Working Group.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02313-18. doi: 10.1128/AAC.02313-18. Print 2019 Apr.


Differences in monocyte: lymphocyte ratio and Tuberculosis disease progression in genetically distinct populations of macaques.

Sibley L, Gooch K, Wareham A, Gray S, Chancellor A, Dowall S, Bate S, Marriott A, Dennis M, White AD, Marsh PD, Fletcher H, Sharpe S.

Sci Rep. 2019 Mar 4;9(1):3340. doi: 10.1038/s41598-019-39819-6.


Using Exploratory Trials to Identify Relevant Contexts and Mechanisms in Complex Electronic Health Interventions: Evaluating the Electronic Patient-Reported Outcome Tool.

Steele Gray C, Gravesande J, Hans PK, Nie JX, Sharpe S, Loganathan M, Lyons R, Cott C.

JMIR Form Res. 2019 Feb 27;3(1):e11950. doi: 10.2196/11950.


Family reflections: Prematurity-practitioner influence on the lived experience of the parenting role.

Sharpe S.

Pediatr Res. 2019 Feb 21. doi: 10.1038/s41390-019-0351-6. [Epub ahead of print] No abstract available.


A brief report of toxicity end points of HER2 vaccines for the treatment of patients with HER2+ breast cancer.

Costa R, Zaman S, Sharpe S, Helenowski I, Shaw C, Han H, Soliman H, Czerniecki B.

Drug Des Devel Ther. 2019 Jan 14;13:309-316. doi: 10.2147/DDDT.S188925. eCollection 2019. Review.


Detection of broadleaf weeds growing in turfgrass with convolutional neural networks.

Yu J, Sharpe SM, Schumann AW, Boyd NS.

Pest Manag Sci. 2019 Jan 22. doi: 10.1002/ps.5349. [Epub ahead of print]


In vitro activity of EDTA and TOL-463 against Neisseria gonorrhoeae.

Nash EE, Henning TC, Pham CD, Pettus K, Sharpe S, Kersh EN.

Diagn Microbiol Infect Dis. 2019 Apr;93(4):369-371. doi: 10.1016/j.diagmicrobio.2018.10.021. Epub 2018 Nov 10.


Staging breast cancer by sentinel lymph node biopsy: Do patients with a single negative sentinel node (N=1) experience worse outcomes than those with multiple negative sentinel nodes (N>1)?

Wilkerson A, Averbook B, Joseph N, Sharpe S, Li B.

Surg Oncol. 2018 Sep;27(3):327-332. doi: 10.1016/j.suronc.2018.05.011. Epub 2018 May 4.


Extrusion 3D Printing of Paracetamol Tablets from a Single Formulation with Tunable Release Profiles Through Control of Tablet Geometry.

Khaled SA, Alexander MR, Irvine DJ, Wildman RD, Wallace MJ, Sharpe S, Yoo J, Roberts CJ.

AAPS PharmSciTech. 2018 Nov;19(8):3403-3413. doi: 10.1208/s12249-018-1107-z. Epub 2018 Aug 10.


Unsupervised CT Lung Image Segmentation of a Mycobacterium Tuberculosis Infection Model.

Gordaliza PM, Muñoz-Barrutia A, Abella M, Desco M, Sharpe S, Vaquero JJ.

Sci Rep. 2018 Jun 28;8(1):9802. doi: 10.1038/s41598-018-28100-x.


Role of Liquid-Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins.

Muiznieks LD, Sharpe S, Pomès R, Keeley FW.

J Mol Biol. 2018 Nov 2;430(23):4741-4753. doi: 10.1016/j.jmb.2018.06.010. Epub 2018 Jun 8. Review.


Computed Tomography-Based Biomarker for Longitudinal Assessment of Disease Burden in Pulmonary Tuberculosis.

Gordaliza PM, Muñoz-Barrutia A, Via LE, Sharpe S, Desco M, Vaquero JJ.

Mol Imaging Biol. 2019 Feb;21(1):19-24. doi: 10.1007/s11307-018-1215-x.


Effects of N-methyl-d-aspartate receptor (NMDAr) uncompetitive antagonists in a delay discounting paradigm using a concurrent-chains procedure.

Yates JR, Gunkel BT, Rogers KK, Breitenstein KA, Hughes MN, Johnson AB, Sharpe SM.

Behav Brain Res. 2018 Sep 3;349:125-129. doi: 10.1016/j.bbr.2018.03.039. Epub 2018 Mar 28.


Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines.

Harris SA, White A, Stockdale L, Tanner R, Sibley L, Sarfas C, Meyer J, Peter J, O'Shea MK, Manjaly Thomas ZR, Hamidi A, Satti I, Dennis MJ, McShane H, Sharpe S.

Tuberculosis (Edinb). 2018 Jan;108:99-105. doi: 10.1016/ Epub 2017 Nov 15.


The Optimization of an eHealth Solution (Thought Spot) with Transition-Aged Youth in Postsecondary Settings: Participatory Design Research.

VanHeerwaarden N, Ferguson G, Abi-Jaoude A, Johnson A, Hollenberg E, Chaim G, Cleverley K, Eysenbach G, Henderson J, Levinson A, Robb J, Sharpe S, Voineskos A, Wiljer D.

J Med Internet Res. 2018 Mar 6;20(3):e79. doi: 10.2196/jmir.8102.


Refinement and reduction through application of a quantitative score system for estimation of TB-induced disease burden using computed tomography.

Sharpe SA, Smyth D, McIntyre A, Gleeson F, Dennis MJ.

Lab Anim. 2018 Dec;52(6):599-610. doi: 10.1177/0023677218757815. Epub 2018 Feb 26.


3D extrusion printing of high drug loading immediate release paracetamol tablets.

Khaled SA, Alexander MR, Wildman RD, Wallace MJ, Sharpe S, Yoo J, Roberts CJ.

Int J Pharm. 2018 Mar 1;538(1-2):223-230. doi: 10.1016/j.ijpharm.2018.01.024. Epub 2018 Jan 17.


Mobile Web-Based Follow-up for Postoperative ACL Reconstruction: A Single-Center Experience.

Higgins J, Semple J, Murnaghan L, Sharpe S, Theodoropoulos J.

Orthop J Sports Med. 2017 Dec 22;5(12):2325967117745278. doi: 10.1177/2325967117745278. eCollection 2017 Dec.


Accurate Measurement of the Optical Constants n and k for a Series of 57 Inorganic and Organic Liquids for Optical Modeling and Detection.

Myers TL, Tonkyn RG, Danby TO, Taubman MS, Bernacki BE, Birnbaum JC, Sharpe SW, Johnson TJ.

Appl Spectrosc. 2018 Apr;72(4):535-550. doi: 10.1177/0003702817742848. Epub 2017 Dec 29.


Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides.

Stone TA, Cole GB, Nguyen HQ, Sharpe S, Deber CM.

Bioorg Med Chem. 2018 Mar 15;26(6):1189-1196. doi: 10.1016/j.bmc.2017.10.020. Epub 2017 Oct 21.


Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design.

Laddy DJ, Bonavia A, Hanekom WA, Kaushal D, Williams A, Roederer M, Seder RA, Sharpe S, Verreck FAW, Darrah PA.

Infect Immun. 2018 Jan 22;86(2). pii: e00776-17. doi: 10.1128/IAI.00776-17. Print 2018 Feb.


Cancer Risk Associated with Nuclear Atypia in Cytologically Indeterminate Thyroid Nodules: A Systematic Review and Meta-Analysis.

Valderrabano P, Khazai L, Thompson ZJ, Sharpe SC, Tarasova VD, Otto KJ, Hallanger-Johnson JE, Wadsworth JT, Wenig BM, Chung CH, Centeno BA, McIver B.

Thyroid. 2018 Feb;28(2):210-219. doi: 10.1089/thy.2017.0419. Epub 2017 Dec 21.


CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.

Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M, Marshall B, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P, Mansour S.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10956-E10964. doi: 10.1073/pnas.1708252114. Epub 2017 Nov 20.


FRET Analysis of the Promiscuous yet Specific Interactions of the HIV-1 Vpu Transmembrane Domain.

Cole GB, Reichheld SE, Sharpe S.

Biophys J. 2017 Nov 7;113(9):1992-2003. doi: 10.1016/j.bpj.2017.09.010.


Review of lattice results concerning low-energy particle physics: Flavour Lattice Averaging Group (FLAG).

Aoki S, Aoki Y, Bečirević D, Bernard C, Blum T, Colangelo G, Della Morte M, Dimopoulos P, Dürr S, Fukaya H, Golterman M, Gottlieb S, Hashimoto S, Heller UM, Horsley R, Jüttner A, Kaneko T, Lellouch L, Leutwyler H, Lin CD, Lubicz V, Lunghi E, Mawhinney R, Onogi T, Pena C, Sachrajda CT, Sharpe SR, Simula S, Sommer R, Vladikas A, Wenger U, Wittig H.

Eur Phys J C Part Fields. 2017;77(2):112. doi: 10.1140/epjc/s10052-016-4509-7. Epub 2017 Feb 17. Review.


EXPRESS: Accurate Measurement of the Optical Constants n and k for a Series of 57 Inorganic and Organic Liquids for Optical Modeling and Detection.

Myers TL, Tonkyn RG, Danby TO, Taubman MS, Bernacki BE, Birnbaum JC, Sharpe SW, Johnson T.

Appl Spectrosc. 2017 Jan 1:3702817735817. doi: 10.1177/0003702817735817. [Epub ahead of print] No abstract available.


Texting during stair negotiation and implications for fall risk.

Hashish R, Toney-Bolger ME, Sharpe SS, Lester BD, Mulliken A.

Gait Posture. 2017 Oct;58:409-414. doi: 10.1016/j.gaitpost.2017.09.004. Epub 2017 Sep 5.


Laparoscopic Distal Pancreatectomy for Cancer Provides Oncologic Outcomes and Overall Survival Identical to Open Distal Pancreatectomy.

Kantor O, Bryan DS, Talamonti MS, Lutfi W, Sharpe S, Winchester DJ, Prinz RA, Baker MS.

J Gastrointest Surg. 2017 Oct;21(10):1620-1625. doi: 10.1007/s11605-017-3506-y. Epub 2017 Aug 1.


The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.

Brennan MJ, Tanner R, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey DA, Izzo A, Sharpe S, Williams A, Penn-Nicholson A, Erasmus M, Stylianou E, Hoft DF, McShane H, Fletcher HA.

Clin Vaccine Immunol. 2017 Sep 5;24(9). pii: e00142-17. doi: 10.1128/CVI.00142-17. Print 2017 Sep. Review.


3D printing of tablets using inkjet with UV photoinitiation.

Clark EA, Alexander MR, Irvine DJ, Roberts CJ, Wallace MJ, Sharpe S, Yoo J, Hague RJM, Tuck CJ, Wildman RD.

Int J Pharm. 2017 Aug 30;529(1-2):523-530. doi: 10.1016/j.ijpharm.2017.06.085. Epub 2017 Jun 30.


Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers.

Wang H, Muiznieks LD, Ghosh P, Williams D, Solarski M, Fang A, Ruiz-Riquelme A, Pomès R, Watts JC, Chakrabartty A, Wille H, Sharpe S, Schmitt-Ulms G.

Elife. 2017 Jun 26;6. pii: e28401. doi: 10.7554/eLife.28401.


Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.

Chancellor A, White A, Tocheva AS, Fenn JR, Dennis M, Tezera L, Singhania A, Elliott T, Tebruegge M, Elkington P, Gadola S, Sharpe S, Mansour S.

Tuberculosis (Edinb). 2017 Jul;105:86-95. doi: 10.1016/ Epub 2017 Apr 28.


A metastatic secretory gastric plasmacytoma with aberrant CD3 expression in a dog.

Atherton MJ, Vazquez-Sanmartin S, Sharpe S, Waugh EM, Morris JS.

Vet Clin Pathol. 2017 Sep;46(3):520-525. doi: 10.1111/vcp.12503. Epub 2017 Jun 5.


Direct observation of structure and dynamics during phase separation of an elastomeric protein.

Reichheld SE, Muiznieks LD, Keeley FW, Sharpe S.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4408-E4415. doi: 10.1073/pnas.1701877114. Epub 2017 May 15.


Administrative Preparedness Strategies: Expediting Procurement and Contracting Cycle Times During an Emergency.

Hurst D, Sharpe S, Yeager VA.

Public Health Rep. 2017 May/Jun;132(3):294-297. doi: 10.1177/0033354917698131. Epub 2017 Apr 10.


An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques.

Sharpe SA, White AD, Sibley L, Gleeson F, Hall GA, Basaraba RJ, McIntyre A, Clark SO, Gooch K, Marsh PD, Williams A, Dennis MJ.

PLoS One. 2017 Mar 8;12(3):e0171906. doi: 10.1371/journal.pone.0171906. eCollection 2017.


The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2017 Mar 3;7:43478. doi: 10.1038/srep43478. Erratum in: Sci Rep. 2019 Apr 3;9(1):5596.


Effects of Group I metabotropic glutamate receptor antagonists on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting task in rats: Contribution of delay presentation order.

Yates JR, Rogers KK, Gunkel BT, Prior NA, Hughes MN, Sharpe SM, Campbell HL, Johnson AB, Keller MG, Breitenstein KA, Shults HN.

Behav Brain Res. 2017 Mar 30;322(Pt A):29-33. doi: 10.1016/j.bbr.2017.01.015. Epub 2017 Jan 12.


Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods.

Rhodes SJ, Sarfas C, Knight GM, White A, Pathan AA, McShane H, Evans TG, Fletcher H, Sharpe S, White RG.

Clin Vaccine Immunol. 2017 Mar 6;24(3). pii: e00525-16. doi: 10.1128/CVI.00525-16. Print 2017 Mar.


Effectiveness of the YourCall™ text message intervention to reduce harmful drinking in patients discharged from trauma wards: protocol for a randomised controlled trial.

Ameratunga S, Kool B, Sharpe S, Reid P, Lee A, Civil I, Smith G, Thornton V, Walker M, Whittaker R.

BMC Public Health. 2017 Jan 9;17(1):48. doi: 10.1186/s12889-016-3967-z.


Laparoscopic pancreaticoduodenectomy for adenocarcinoma provides short-term oncologic outcomes and long-term overall survival rates similar to those for open pancreaticoduodenectomy.

Kantor O, Talamonti MS, Sharpe S, Lutfi W, Winchester DJ, Roggin KK, Bentrem DJ, Prinz RA, Baker MS.

Am J Surg. 2017 Mar;213(3):512-515. doi: 10.1016/j.amjsurg.2016.10.030. Epub 2016 Dec 28.


Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations.

Sharpe S, White A, Sarfas C, Sibley L, Gleeson F, McIntyre A, Basaraba R, Clark S, Hall G, Rayner E, Williams A, Marsh PD, Dennis M.

Tuberculosis (Edinb). 2016 Dec;101:174-190. doi: 10.1016/ Epub 2016 Oct 8.


Enhancing Self-Efficacy for Help-Seeking Among Transition-Aged Youth in Postsecondary Settings With Mental Health and/or Substance Use Concerns, Using Crowd-Sourced Online and Mobile Technologies: The Thought Spot Protocol.

Wiljer D, Abi-Jaoude A, Johnson A, Ferguson G, Sanches M, Levinson A, Robb J, Heffernan O, Herzog T, Chaim G, Cleverley K, Eysenbach G, Henderson J, Hoch JS, Hollenberg E, Jiang H, Isaranuwatchai W, Law M, Sharpe S, Tripp T, Voineskos A.

JMIR Res Protoc. 2016 Nov 4;5(4):e201. doi: 10.2196/resprot.6446.


Live and inactivated vaccine regimens against caecal Salmonella Typhimurium colonisation in laying hens.

Groves PJ, Sharpe SM, Muir WI, Pavic A, Cox JM.

Aust Vet J. 2016 Oct;94(10):387-93. doi: 10.1111/avj.12490.

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