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Smoking affects gene expression in blood of patients with ischemic stroke.

Cheng X, Ferino E, Hull H, Jickling GC, Ander BP, Stamova B, Sharp FR.

Ann Clin Transl Neurol. 2019 Aug 22. doi: 10.1002/acn3.50876. [Epub ahead of print]


MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage.

Cheng X, Ander BP, Jickling GC, Zhan X, Hull H, Sharp FR, Stamova B.

J Cereb Blood Flow Metab. 2019 Apr 9:271678X19839501. doi: 10.1177/0271678X19839501. [Epub ahead of print]


Inflammatory, regulatory, and autophagy co-expression modules and hub genes underlie the peripheral immune response to human intracerebral hemorrhage.

Durocher M, Ander BP, Jickling G, Hamade F, Hull H, Knepp B, Liu DZ, Zhan X, Tran A, Cheng X, Ng K, Yee A, Sharp FR, Stamova B.

J Neuroinflammation. 2019 Mar 5;16(1):56. doi: 10.1186/s12974-019-1433-4.


MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats.

Lv B, Cheng X, Sharp FR, Ander BP, Liu DZ.

Front Neurosci. 2018 Oct 24;12:767. doi: 10.3389/fnins.2018.00767. eCollection 2018.


MicroRNA-based therapeutics in central nervous system injuries.

Sun P, Liu DZ, Jickling GC, Sharp FR, Yin KJ.

J Cereb Blood Flow Metab. 2018 Jul;38(7):1125-1148. doi: 10.1177/0271678X18773871. Epub 2018 Apr 30. Review.


The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes.

Stamova B, Ander BP, Jickling G, Hamade F, Durocher M, Zhan X, Liu DZ, Cheng X, Hull H, Yee A, Ng K, Shroff N, Sharp FR.

J Cereb Blood Flow Metab. 2018 Apr 13:271678X18769513. doi: 10.1177/0271678X18769513. [Epub ahead of print]


HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke.

Shroff N, Ander BP, Zhan X, Stamova B, Liu D, Hull H, Hamade FR, Dykstra-Aiello C, Ng K, Sharp FR, Jickling GC.

Transl Stroke Res. 2019 Feb;10(1):19-25. doi: 10.1007/s12975-018-0619-x. Epub 2018 Apr 13.


Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer's Disease Brain: A Review.

Zhan X, Stamova B, Sharp FR.

Front Aging Neurosci. 2018 Feb 22;10:42. doi: 10.3389/fnagi.2018.00042. eCollection 2018. Review.


Cleaved β-Actin May Contribute to DNA Fragmentation Following Very Brief Focal Cerebral Ischemia.

Ye Z, Ander BP, Sharp FR, Zhan X.

J Neuropathol Exp Neurol. 2018 Mar 1;77(3):260-265. doi: 10.1093/jnen/nly003.


The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.

Oleszycka E, McCluskey S, Sharp FA, Muñoz-Wolf N, Hams E, Gorman AL, Fallon PG, Lavelle EC.

Eur J Immunol. 2018 Apr;48(4):705-715. doi: 10.1002/eji.201747150. Epub 2018 Feb 15.


Clinical Reasoning: A case of altered mental status, not otherwise specified.

Swor DE, Sharp FR, Jickling GC.

Neurology. 2017 Sep 26;89(13):e154-e158. doi: 10.1212/WNL.0000000000004416. No abstract available.


A technical diving-related burns case: treatment in a remote location.

Sharp FC, Sayer MD.

Diving Hyperb Med. 2017 Jun;47(2):127-130.


Biomarkers of Acute Stroke Etiology (BASE) Study Methodology.

Jauch EC, Barreto AD, Broderick JP, Char DM, Cucchiara BL, Devlin TG, Haddock AJ, Hicks WJ, Hiestand BC, Jickling GC, June J, Liebeskind DS, Lowenkopf TJ, Miller JB, O'Neill J, Schoonover TL, Sharp FR, Peacock WF.

Transl Stroke Res. 2017 May 5. doi: 10.1007/s12975-017-0537-3. [Epub ahead of print]


Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain.

Schumann CM, Sharp FR, Ander BP, Stamova B.

Mol Autism. 2017 Feb 7;8:4. doi: 10.1186/s13229-017-0117-0. eCollection 2017.


Twenty-Five Years of Health Economics: A Tribute to Alan Maynard and Acknowledgement of the Work of the Editorial Board.

Briggs A, Hutton J, Jones AM, Mullahy J, Sharp F, Stearns S.

Health Econ. 2017 Jan;26(1):3-5. doi: 10.1002/hec.3456. No abstract available.


Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis.

Tylee DS, Hess JL, Quinn TP, Barve R, Huang H, Zhang-James Y, Chang J, Stamova BS, Sharp FR, Hertz-Picciotto I, Faraone SV, Kong SW, Glatt SJ.

Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):181-201. doi: 10.1002/ajmg.b.32511. Epub 2016 Nov 11.


Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci.

Dykstra-Aiello C, Jickling GC, Ander BP, Shroff N, Zhan X, Liu D, Hull H, Orantia M, Stamova BS, Sharp FR.

Stroke. 2016 Dec;47(12):2896-2903. Epub 2016 Nov 10.


Leukocyte response is regulated by microRNA let7i in patients with acute ischemic stroke.

Jickling GC, Ander BP, Shroff N, Orantia M, Stamova B, Dykstra-Aiello C, Hull H, Zhan X, Liu D, Sharp FR.

Neurology. 2016 Nov 22;87(21):2198-2205. Epub 2016 Oct 26.


Gram-negative bacterial molecules associate with Alzheimer disease pathology.

Zhan X, Stamova B, Jin LW, DeCarli C, Phinney B, Sharp FR.

Neurology. 2016 Nov 29;87(22):2324-2332. Epub 2016 Oct 26.


Inhibition of Src family kinases improves cognitive function after intraventricular hemorrhage or intraventricular thrombin.

Liu DZ, Waldau B, Ander BP, Zhan X, Stamova B, Jickling GC, Lyeth BG, Sharp FR.

J Cereb Blood Flow Metab. 2017 Jul;37(7):2359-2367. doi: 10.1177/0271678X16666291. Epub 2016 Jan 1.


Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke.

Turner RJ, Sharp FR.

Front Cell Neurosci. 2016 Mar 4;10:56. doi: 10.3389/fncel.2016.00056. eCollection 2016. Review.


Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats.

Liu da Z, Jickling GC, Ander BP, Hull H, Zhan X, Cox C, Shroff N, Dykstra-Aiello C, Stamova B, Sharp FR.

J Cereb Blood Flow Metab. 2016 Aug;36(8):1374-83. doi: 10.1177/0271678X15610786. Epub 2015 Oct 19.


MicroRNA and mRNA Expression Changes in Steroid Naïve and Steroid Treated DMD Patients.

Liu DZ, Stamova B, Hu S, Ander BP, Jickling GC, Zhan X, Sharp FR, Wong B.

J Neuromuscul Dis. 2015 Sep 22;2(4):387-396.


Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains.

Stamova B, Ander BP, Barger N, Sharp FR, Schumann CM.

J Child Neurol. 2015 Dec;30(14):1930-46. doi: 10.1177/0883073815602067. Epub 2015 Sep 8.


Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders.

Ander BP, Barger N, Stamova B, Sharp FR, Schumann CM.

Mol Autism. 2015 Jun 19;6:37. doi: 10.1186/s13229-015-0029-9. eCollection 2015.


Targeting neutrophils in ischemic stroke: translational insights from experimental studies.

Jickling GC, Liu D, Ander BP, Stamova B, Zhan X, Sharp FR.

J Cereb Blood Flow Metab. 2015 Jun;35(6):888-901. doi: 10.1038/jcbfm.2015.45. Epub 2015 Mar 25. Review.


Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain.

Zhan X, Cox C, Ander BP, Liu D, Stamova B, Jin LW, Jickling GC, Sharp FR.

J Alzheimers Dis. 2015;46(2):507-23. doi: 10.3233/JAD-143072.


Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain.

Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp FR.

J Alzheimers Dis. 2015;44(4):1213-29. doi: 10.3233/JAD-142013.


Biomarker panels in ischemic stroke.

Jickling GC, Sharp FR.

Stroke. 2015 Mar;46(3):915-20. doi: 10.1161/STROKEAHA.114.005604. Epub 2015 Feb 5. No abstract available.


Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen.

Saluja SS, Hanlon DJ, Sharp FA, Hong E, Khalil D, Robinson E, Tigelaar R, Fahmy TM, Edelson RL.

Int J Nanomedicine. 2014 Nov 12;9:5231-46. doi: 10.2147/IJN.S66639. eCollection 2014.


A carbon nanotube-polymer composite for T-cell therapy.

Fadel TR, Sharp FA, Vudattu N, Ragheb R, Garyu J, Kim D, Hong E, Li N, Haller GL, Pfefferle LD, Justesen S, Herold KC, Fahmy TM.

Nat Nanotechnol. 2014 Aug;9(8):639-47. doi: 10.1038/nnano.2014.154. Epub 2014 Aug 3. Erratum in: Nat Nanotechnol. 2014 Sep;9(9):723. Harold, Kevin C [corrected to Herold, Kevan C].


Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.

Sellier C, Hwang VJ, Dandekar R, Durbin-Johnson B, Charlet-Berguerand N, Ander BP, Sharp FR, Angkustsiri K, Simon TJ, Tassone F.

PLoS One. 2014 Aug 1;9(8):e103884. doi: 10.1371/journal.pone.0103884. eCollection 2014.


Modeling immunity and inflammation in stroke: differences between rodents and humans?

Sharp FR, Jickling GC.

Stroke. 2014 Sep;45(9):e179-80. doi: 10.1161/STROKEAHA.114.005639. Epub 2014 Jul 24. No abstract available.


Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic.

Stamova B, Jickling GC, Ander BP, Zhan X, Liu D, Turner R, Ho C, Khoury JC, Bushnell C, Pancioli A, Jauch EC, Broderick JP, Sharp FR.

PLoS One. 2014 Jul 18;9(7):e102550. doi: 10.1371/journal.pone.0102550. eCollection 2014.


Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities.

Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp FR.

Alzheimer Dis Assoc Disord. 2014 Jul-Sep;28(3):226-33. doi: 10.1097/WAD.0000000000000022.


Improving the translation of animal ischemic stroke studies to humans.

Jickling GC, Sharp FR.

Metab Brain Dis. 2015 Apr;30(2):461-7. doi: 10.1007/s11011-014-9499-2. Epub 2014 Feb 15. Review.


Myelin injury and degraded myelin vesicles in Alzheimer's disease.

Zhan X, Jickling GC, Ander BP, Liu D, Stamova B, Cox C, Jin LW, DeCarli C, Sharp FR.

Curr Alzheimer Res. 2014 Mar;11(3):232-8.


Inhibition of SRC family kinases protects hippocampal neurons and improves cognitive function after traumatic brain injury.

Liu DZ, Sharp FR, Van KC, Ander BP, Ghiasvand R, Zhan X, Stamova B, Jickling GC, Lyeth BG.

J Neurotrauma. 2014 Jul 15;31(14):1268-76. doi: 10.1089/neu.2013.3250. Epub 2014 Apr 17.


Heat shock proteins in the brain: role of Hsp70, Hsp 27, and HO-1 (Hsp32) and their therapeutic potential.

Sharp FR, Zhan X, Liu DZ.

Transl Stroke Res. 2013 Dec;4(6):685-92. doi: 10.1007/s12975-013-0271-4. Epub 2013 Aug 3. Review.


Genetic susceptibility and neurotransmitters in Tourette syndrome.

Paschou P, Fernandez TV, Sharp F, Heiman GA, Hoekstra PJ.

Int Rev Neurobiol. 2013;112:155-77. doi: 10.1016/B978-0-12-411546-0.00006-8. Review.


Hemorrhagic transformation after ischemic stroke in animals and humans.

Jickling GC, Liu D, Stamova B, Ander BP, Zhan X, Lu A, Sharp FR.

J Cereb Blood Flow Metab. 2014 Feb;34(2):185-99. doi: 10.1038/jcbfm.2013.203. Epub 2013 Nov 27. Review.


Autophagy in the brain of neonates following hypoxia-ischemia shows sex- and region-specific effects.

Weis SN, Toniazzo AP, Ander BP, Zhan X, Careaga M, Ashwood P, Wyse AT, Netto CA, Sharp FR.

Neuroscience. 2014 Jan 3;256:201-9. doi: 10.1016/j.neuroscience.2013.10.046. Epub 2013 Nov 1.


Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders.

Stamova BS, Tian Y, Nordahl CW, Shen MD, Rogers S, Amaral DG, Sharp FR.

Mol Autism. 2013 Sep 4;4(1):30. doi: 10.1186/2040-2392-4-30.


An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways.

Peng B, Zhu D, Ander BP, Zhang X, Xue F, Sharp FR, Yang X.

PLoS One. 2013 Jul 3;8(7):e67672. doi: 10.1371/journal.pone.0067672. Print 2013.


Whole genome expression of cellular response to stroke.

Sharp FR, Jickling GC.

Stroke. 2013 Jun;44(6 Suppl 1):S23-5. doi: 10.1161/STROKEAHA.112.679357. Review. No abstract available.


RNA-based blood genomics as an investigative tool and prospective biomarker for ischemic stroke.

Cox C, Sharp FR.

Neurol Res. 2013 Jun;35(5):457-64. doi: 10.1179/1743132813Y.0000000212. Epub 2013 Apr 29. Review.


Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study.

Apperson ML, Tian Y, Stamova B, Ander BP, Jickling GC, Agius MA, Sharp FR.

J Neuroimmunol. 2013 Apr 15;257(1-2):90-6. doi: 10.1016/j.jneuroim.2013.02.004. Epub 2013 Mar 9.


RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke.

Jickling GC, Ander BP, Stamova B, Zhan X, Liu D, Rothstein L, Verro P, Khoury J, Jauch EC, Pancioli AM, Broderick JP, Sharp FR.

Ann Neurol. 2013 Aug;74(2):232-40. doi: 10.1002/ana.23883. Epub 2013 Sep 10.


Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study.

Tian Y, Stamova B, Ander BP, Jickling GC, Gunther JR, Corbett BA, Bos-Veneman NG, Hoekstra PJ, Schweitzer JB, Sharp FR.

BMC Med Genomics. 2012 Oct 30;5:49. doi: 10.1186/1755-8794-5-49.


The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.

Mori A, Oleszycka E, Sharp FA, Coleman M, Ozasa Y, Singh M, O'Hagan DT, Tajber L, Corrigan OI, McNeela EA, Lavelle EC.

Eur J Immunol. 2012 Oct;42(10):2709-19. doi: 10.1002/eji.201242372. Epub 2012 Aug 6.

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