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Items: 1 to 50 of 52

1.

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.

Guo D, Lui GYL, Lai SL, Wilmott JS, Tikoo S, Jackett LA, Quek C, Brown DL, Sharp DM, Kwan RYQ, Chacon D, Wong JH, Beck D, van Geldermalsen M, Holst J, Thompson JF, Mann GJ, Scolyer RA, Stow JL, Weninger W, Haass NK, Beaumont KA.

Int J Cancer. 2019 Jun 15;144(12):3070-3085. doi: 10.1002/ijc.32064. Epub 2019 Jan 3.

PMID:
30556600
2.

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma.

Gallagher SJ, Gunatilake D, Beaumont KA, Sharp DM, Tiffen JC, Heinemann A, Weninger W, Haass NK, Wilmott JS, Madore J, Ferguson PM, Rizos H, Hersey P.

Int J Cancer. 2018 May 1;142(9):1926-1937. doi: 10.1002/ijc.31199. Epub 2017 Dec 20.

3.

The effect of Me2SO overexposure during cryopreservation on HOS TE85 and hMSC viability, growth and quality.

Morris TJ, Picken A, Sharp DMC, Slater NKH, Hewitt CJ, Coopman K.

Cryobiology. 2016 Dec;73(3):367-375. doi: 10.1016/j.cryobiol.2016.09.004. Epub 2016 Sep 20.

4.

Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells.

Beaumont KA, Hill DS, Daignault SM, Lui GYL, Sharp DM, Gabrielli B, Weninger W, Haass NK.

J Invest Dermatol. 2016 Jul;136(7):1479-1489. doi: 10.1016/j.jid.2016.02.805. Epub 2016 Mar 10.

5.

A novel rhodopsin point mutation, proline-170-histidine, associated with sectoral retinitis pigmentosa.

Shah SP, Wong F, Sharp DM, Vincent AL.

Ophthalmic Genet. 2014 Dec;35(4):241-7. doi: 10.3109/13816810.2014.924014. Epub 2014 Jun 11.

PMID:
24918165
6.

Targeting glutamine transport to suppress melanoma cell growth.

Wang Q, Beaumont KA, Otte NJ, Font J, Bailey CG, van Geldermalsen M, Sharp DM, Tiffen JC, Ryan RM, Jormakka M, Haass NK, Rasko JE, Holst J.

Int J Cancer. 2014 Sep 1;135(5):1060-71. doi: 10.1002/ijc.28749. Epub 2014 Feb 17.

7.

P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration.

Yamagishi T, Sahni S, Sharp DM, Arvind A, Jansson PJ, Richardson DR.

J Biol Chem. 2013 Nov 1;288(44):31761-71. doi: 10.1074/jbc.M113.514091. Epub 2013 Sep 23.

8.

Amphipathic polymer-mediated uptake of trehalose for dimethyl sulfoxide-free human cell cryopreservation.

Sharp DM, Picken A, Morris TJ, Hewitt CJ, Coopman K, Slater NK.

Cryobiology. 2013 Dec;67(3):305-11. doi: 10.1016/j.cryobiol.2013.09.002. Epub 2013 Sep 14.

9.

A randomised controlled trial comparing graded exercise treatment and usual physiotherapy for patients with non-specific neck pain (the GET UP neck pain trial).

McLean SM, Klaber Moffett JA, Sharp DM, Gardiner E.

Man Ther. 2013 Jun;18(3):199-205. doi: 10.1016/j.math.2012.09.005. Epub 2012 Oct 22.

PMID:
23085116
10.

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action.

Lui GY, Obeidy P, Ford SJ, Tselepis C, Sharp DM, Jansson PJ, Kalinowski DS, Kovacevic Z, Lovejoy DB, Richardson DR.

Mol Pharmacol. 2013 Jan;83(1):179-90. doi: 10.1124/mol.112.081893. Epub 2012 Oct 16.

PMID:
23074173
11.

Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.

Lovejoy DB, Sharp DM, Seebacher N, Obeidy P, Prichard T, Stefani C, Basha MT, Sharpe PC, Jansson PJ, Kalinowski DS, Bernhardt PV, Richardson DR.

J Med Chem. 2012 Aug 23;55(16):7230-44. doi: 10.1021/jm300768u. Epub 2012 Aug 3.

PMID:
22861499
12.

An investigation to determine the association between neck pain and upper limb disability for patients with non-specific neck pain: a secondary analysis.

McLean SM, Moffett JK, Sharp DM, Gardiner E.

Man Ther. 2011 Oct;16(5):434-9. doi: 10.1016/j.math.2011.01.003. Epub 2011 Feb 22.

PMID:
21345714
13.

Psychological impact and acceptability of magnetic resonance imaging and X-ray mammography: the MARIBS Study.

Hutton J, Walker LG, Gilbert FJ, Evans DG, Eeles R, Kwan-Lim GE, Thompson D, Pointon LJ, Sharp DM, Leach MO; UK Study Group for MRI Screening in Women at High Risk Study.

Br J Cancer. 2011 Feb 15;104(4):578-86. doi: 10.1038/bjc.2011.1.

14.

Risk factors for the onset of non-specific neck pain: a systematic review.

McLean SM, May S, Klaber-Moffett J, Sharp DM, Gardiner E.

J Epidemiol Community Health. 2010 Jul;64(7):565-72. doi: 10.1136/jech.2009.090720. Epub 2010 May 12. Review.

PMID:
20466711
15.

Alterations in the Th1/Th2 balance in breast cancer patients using reflexology and scalp massage.

Green VL, Alexandropoulou A, Walker MB, Walker AA, Sharp DM, Walker LG, Greenman J.

Exp Ther Med. 2010 Jan;1(1):97-108. Epub 2010 Jan 1.

16.

Demographic characteristics of patients using a fully integrated psychosocial support service for cancer patients.

Sharp DM, Walker MB, Bateman JS, Braid F, Hebblewhite C, Hope T, Lines M, Walker AA, Walker LG.

BMC Res Notes. 2009 Dec 15;2:253. doi: 10.1186/1756-0500-2-253.

17.

A randomised, controlled trial of the psychological effects of reflexology in early breast cancer.

Sharp DM, Walker MB, Chaturvedi A, Upadhyay S, Hamid A, Walker AA, Bateman JS, Braid F, Ellwood K, Hebblewhite C, Hope T, Lines M, Walker LG.

Eur J Cancer. 2010 Jan;46(2):312-22. doi: 10.1016/j.ejca.2009.10.006. Epub 2009 Nov 10.

PMID:
19906525
18.

Transient retinal effects of 5,6-dimethylxanthenone-4-acetic acid (DMXAA, ASA404), an antitumor vascular-disrupting agent in phase I clinical trials.

Jameson MB, Sharp DM, Sissingh JI, Hogg CR, Thompson PI, McKeage MJ, Jeffery M, Waller S, Acton G, Green C, Baguley BC.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2553-9. doi: 10.1167/iovs.08-2068. Epub 2009 Apr 22.

PMID:
19387077
19.

Psychosocial factors and quality of life in colorectal cancer.

Sharma A, Walker AA, Sharp DM, Monson JR, Walker LG.

Surgeon. 2007 Dec;5(6):344-54. Review.

PMID:
18080609
20.

Colorectal MDTs: the team's perspective.

Sharma A, Sharp DM, Walker LG, Monson JR.

Colorectal Dis. 2008 Jan;10(1):63-8.

PMID:
18078461
21.

Stress and burnout in colorectal and vascular surgical consultants working in the UK National Health Service.

Sharma A, Sharp DM, Walker LG, Monson JR.

Psychooncology. 2008 Jun;17(6):570-6.

PMID:
17935146
22.

Predictors of early postoperative quality of life after elective resection for colorectal cancer.

Sharma A, Sharp DM, Walker LG, Monson JR.

Ann Surg Oncol. 2007 Dec;14(12):3435-42. Epub 2007 Sep 27.

PMID:
17896155
23.

Reversible optic neuropathy due to metronidazole.

McGrath NM, Kent-Smith B, Sharp DM.

Clin Exp Ophthalmol. 2007 Aug;35(6):585-6.

PMID:
17760644
24.

Stress and burnout among colorectal surgeons and colorectal nurse specialists working in the National Health Service.

Sharma A, Sharp DM, Walker LG, Monson JR.

Colorectal Dis. 2008 May;10(4):397-406. Epub 2007 Aug 16.

PMID:
17711498
25.

Patient personality predicts postoperative stay after colorectal cancer resection.

Sharma A, Sharp DM, Walker LG, Monson JR.

Colorectal Dis. 2008 Feb;10(2):151-6. Epub 2007 Jun 30.

PMID:
17608752
26.

Vascular endothelial growth factor and psychosocial factors in colorectal cancer.

Sharma A, Greenman J, Sharp DM, Walker LG, Monson JR.

Psychooncology. 2008 Jan;17(1):66-73.

PMID:
17410522
27.

Retinal lead toxicity.

Gilhotra JS, Von Lany H, Sharp DM.

Indian J Ophthalmol. 2007 Mar-Apr;55(2):152-4.

30.

Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland.

Durham RC, Chambers JA, Power KG, Sharp DM, Macdonald RR, Major KA, Dow MG, Gumley AI.

Health Technol Assess. 2005 Nov;9(42):1-174. Review.

31.

Randomised controlled trial of prevention of falls in people aged > or =75 with severe visual impairment: the VIP trial.

Campbell AJ, Robertson MC, La Grow SJ, Kerse NM, Sanderson GF, Jacobs RJ, Sharp DM, Hale LA.

BMJ. 2005 Oct 8;331(7520):817. Epub 2005 Sep 23.

32.

A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation.

Hemara-Wahanui A, Berjukow S, Hope CI, Dearden PK, Wu SB, Wilson-Wheeler J, Sharp DM, Lundon-Treweek P, Clover GM, Hoda JC, Striessnig J, Marksteiner R, Hering S, Maw MA.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7553-8. Epub 2005 May 16.

33.

Clinical manifestations of a unique X-linked retinal disorder in a large New Zealand family with a novel mutation in CACNA1F, the gene responsible for CSNB2.

Hope CI, Sharp DM, Hemara-Wahanui A, Sissingh JI, Lundon P, Mitchell EA, Maw MA, Clover GM.

Clin Exp Ophthalmol. 2005 Apr;33(2):129-36.

PMID:
15807819
34.

Return to the asylum: the search for clients with enduring mental health problems in Italy.

Sharp DM.

J Psychiatr Ment Health Nurs. 2004 Oct;11(5):562-8.

PMID:
15450023
35.

Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1.

DuHadaway JB, Du W, Donover S, Baker J, Liu AX, Sharp DM, Muller AJ, Prendergast GC.

Oncogene. 2003 Jun 5;22(23):3578-88.

PMID:
12789266
37.

Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2).

Yue EW, Higley CA, DiMeo SV, Carini DJ, Nugiel DA, Benware C, Benfield PA, Burton CR, Cox S, Grafstrom RH, Sharp DM, Sisk LM, Boylan JF, Muckelbauer JK, Smallwood AM, Chen H, Chang CH, Seitz SP, Trainor GL.

J Med Chem. 2002 Nov 21;45(24):5233-48.

PMID:
12431051
38.

Identification of selective inhibitors of cyclin dependent kinase 4.

Carini DJ, Kaltenbach RF, Liu J, Benfield PA, Boylan J, Boisclair M, Brizuela L, Burton CR, Cox S, Grafstrom R, Harrison BA, Harrison K, Akamike E, Markwalder JA, Nakano Y, Seitz SP, Sharp DM, Trainor GL, Sielecki TM.

Bioorg Med Chem Lett. 2001 Aug 20;11(16):2209-11.

PMID:
11514172
40.

Analysis of site-specific phosphorylation of the retinoblastoma protein during cell cycle progression.

Boylan JF, Sharp DM, Leffet L, Bowers A, Pan W.

Exp Cell Res. 1999 Apr 10;248(1):110-4.

PMID:
10094818
41.
42.
43.

Five group comparisons of treatments for anxiety disorders.

Sharp DM, Power KG, Simpson RJ.

Br J Psychiatry. 1995 Dec;167(6):820-1. No abstract available.

PMID:
8829755
44.

Keep taking the tablets? Inadequate controls for concurrent psychotropic medication in studies of psychological treatments for panic disorder.

Power KG, Sharp DM.

J Psychopharmacol. 1995 Jan;9(1):71-2. doi: 10.1177/026988119500900113. No abstract available.

PMID:
22298698
45.

Controlled comparison of the characteristics of patients with panic disorder.

Simpson RJ, Kazmierczak T, Power KG, Sharp DM.

Br J Gen Pract. 1994 Aug;44(385):352-6.

46.

Linkage analysis in X-linked congenital stationary night blindness.

Aldred MA, Dry KL, Sharp DM, Van Dorp DB, Brown J, Hardwick LJ, Lester DH, Pryde FE, Teague PW, Jay M, et al.

Genomics. 1992 Sep;14(1):99-104. Erratum in: Genomics 1994 Jul 1;22(1):255.

PMID:
1427834
47.

Retinal dysfunction in central serous retinopathy.

Chuang EL, Sharp DM, Fitzke FW, Kemp CM, Holden AL, Bird AC.

Eye (Lond). 1987;1 ( Pt 1):120-5.

PMID:
3556651
48.

Combined hamartoma of the retina and retinal pigment epithelium: the clinical spectrum.

Cosgrove JM, Sharp DM, Bird AC.

Trans Ophthalmol Soc U K. 1986;105 ( Pt 1):106-13.

PMID:
3459294
49.

Massive peri-retinal proliferation following prophylactic treatment of retinal breaks.

Yoshizumi MO, Kreiger AF, Sharp DM.

Trans Ophthalmol Soc N Z. 1983;35:33-6. No abstract available.

PMID:
6579790
50.

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