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Items: 1 to 50 of 243

1.

Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia.

Graham NS, Sharp DJ.

J Neurol Neurosurg Psychiatry. 2019 Nov;90(11):1221-1233. doi: 10.1136/jnnp-2017-317557. Epub 2019 Sep 21. Review.

2.

Traumatic axonal injury influences the cognitive effect of non-invasive brain stimulation.

Li LM, Violante IR, Zimmerman K, Leech R, Hampshire A, Patel M, Opitz A, McArthur D, Jolly A, Carmichael DW, Sharp DJ.

Brain. 2019 Oct 1;142(10):3280-3293. doi: 10.1093/brain/awz252.

3.

In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury.

Gorgoraptis N, Li LM, Whittington A, Zimmerman KA, Maclean LM, McLeod C, Ross E, Heslegrave A, Zetterberg H, Passchier J, Matthews PM, Gunn RN, McMillan TM, Sharp DJ.

Sci Transl Med. 2019 Sep 4;11(508). pii: eaaw1993. doi: 10.1126/scitranslmed.aaw1993.

4.

Dopamine D2/D3 receptor abnormalities after traumatic brain injury and their relationship to post-traumatic depression.

Jolly AE, Raymont V, Cole JH, Whittington A, Scott G, De Simoni S, Searle G, Gunn RN, Sharp DJ.

Neuroimage Clin. 2019 Jul 22;24:101950. doi: 10.1016/j.nicl.2019.101950. [Epub ahead of print]

5.

Validation of a Novel Multivariate Method of Defining HIV-Associated Cognitive Impairment.

Underwood J, De Francesco D, Cole JH, Caan MWA, van Zoest RA, Schmand BA, Sharp DJ, Sabin CA, Reiss P, Winston A; COmorBidity in Relation to AIDS (COBRA) Collaboration and the Pharmacokinetic and clinical Observations in PePle over fiftY (POPPY) Study Group .

Open Forum Infect Dis. 2019 May 3;6(6):ofz198. doi: 10.1093/ofid/ofz198. eCollection 2019 Jun.

6.

Diffusion tensor imaging reveals changes in microstructural integrity along compressed nerve roots that correlate with chronic pain symptoms and motor deficiencies in elderly stenosis patients.

Hughes SW, Hellyer PJ, Sharp DJ, Newbould RD, Patel MC, Strutton PH.

Neuroimage Clin. 2019;23:101880. doi: 10.1016/j.nicl.2019.101880. Epub 2019 May 28.

7.

Stratifying drug treatment of cognitive impairments after traumatic brain injury using neuroimaging.

Jenkins PO, De Simoni S, Bourke NJ, Fleminger J, Scott G, Towey DJ, Svensson W, Khan S, Patel MC, Greenwood R, Friedland D, Hampshire A, Cole JH, Sharp DJ.

Brain. 2019 Aug 1;142(8):2367-2379. doi: 10.1093/brain/awz149.

PMID:
31199462
8.
9.

Cognitive impairment and health-related quality of life following traumatic brain injury.

Gorgoraptis N, Zaw-Linn J, Feeney C, Tenorio-Jimenez C, Niemi M, Malik A, Ham T, Goldstone AP, Sharp DJ.

NeuroRehabilitation. 2019;44(3):321-331. doi: 10.3233/NRE-182618.

10.

Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing.

O'Rourke BP, Kramer AH, Cao LL, Inayathullah M, Guzik H, Rajadas J, Nosanchuk JD, Sharp DJ.

Adv Wound Care (New Rochelle). 2019 Mar 1;8(3):91-100. doi: 10.1089/wound.2018.0827. Epub 2019 Mar 5.

11.

The traumatic brain injury mitigation effects of a new viscoelastic add-on liner.

Siegkas P, Sharp DJ, Ghajari M.

Sci Rep. 2019 Mar 5;9(1):3471. doi: 10.1038/s41598-019-39953-1.

12.

Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism.

Matamoros AJ, Tom VJ, Wu D, Rao Y, Sharp DJ, Baas PW.

J Neurosci. 2019 Mar 13;39(11):2011-2024. doi: 10.1523/JNEUROSCI.1888-18.2018. Epub 2019 Jan 15.

13.

Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.

Lally PJ, Montaldo P, Oliveira V, Soe A, Swamy R, Bassett P, Mendoza J, Atreja G, Kariholu U, Pattnayak S, Sashikumar P, Harizaj H, Mitchell M, Ganesh V, Harigopal S, Dixon J, English P, Clarke P, Muthukumar P, Satodia P, Wayte S, Abernethy LJ, Yajamanyam K, Bainbridge A, Price D, Huertas A, Sharp DJ, Kalra V, Chawla S, Shankaran S, Thayyil S; MARBLE consortium.

Lancet Neurol. 2019 Jan;18(1):35-45. doi: 10.1016/S1474-4422(18)30325-9. Epub 2018 Nov 15.

14.

Cognitive enhancement with Salience Network electrical stimulation is influenced by network structural connectivity.

Li LM, Violante IR, Leech R, Hampshire A, Opitz A, McArthur D, Carmichael DW, Sharp DJ.

Neuroimage. 2019 Jan 15;185:425-433. doi: 10.1016/j.neuroimage.2018.10.069. Epub 2018 Oct 27.

15.

Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation.

Li LM, Violante IR, Leech R, Ross E, Hampshire A, Opitz A, Rothwell JC, Carmichael DW, Sharp DJ.

Hum Brain Mapp. 2019 Feb 15;40(3):904-915. doi: 10.1002/hbm.24420. Epub 2018 Oct 30.

16.

Clinical research cerebral MRI findings in HIV-positive subjects and appropriate controls.

Chhabra S, Underwood J, Cole JH, Caan M, Waldman A, Reiss P, Sabin CA, Sharp DJ, Winston A; CoBRA collaboration.

AIDS. 2018 Sep 10;32(14):2077-2081. doi: 10.1097/QAD.0000000000001910.

PMID:
29912060
17.

Multivariate Pattern Analysis of Volumetric Neuroimaging Data and Its Relationship With Cognitive Function in Treated HIV Disease.

Underwood J, Cole JH, Leech R, Sharp DJ, Winston A; CHARTER group.

J Acquir Immune Defic Syndr. 2018 Aug 1;78(4):429-436. doi: 10.1097/QAI.0000000000001687.

18.

Dopaminergic abnormalities following traumatic brain injury.

Jenkins PO, De Simoni S, Bourke NJ, Fleminger J, Scott G, Towey DJ, Svensson W, Khan S, Patel M, Greenwood R, Cole JH, Sharp DJ.

Brain. 2018 Mar 1;141(3):797-810. doi: 10.1093/brain/awx357.

19.

Spatial patterns of progressive brain volume loss after moderate-severe traumatic brain injury.

Cole JH, Jolly A, de Simoni S, Bourke N, Patel MC, Scott G, Sharp DJ.

Brain. 2018 Mar 1;141(3):822-836. doi: 10.1093/brain/awx354.

20.

No Evidence for Accelerated Aging-Related Brain Pathology in Treated Human Immunodeficiency Virus: Longitudinal Neuroimaging Results From the Comorbidity in Relation to AIDS (COBRA) Project.

Cole JH, Caan MWA, Underwood J, De Francesco D, van Zoest RA, Wit FWNM, Mutsaerts HJMM, Leech R, Geurtsen GJ, Portegies P, Majoie CBLM, Schim van der Loeff MF, Sabin CA, Reiss P, Winston A, Sharp DJ; Comorbidity in Relations to AIDS (COBRA) Collaboration.

Clin Infect Dis. 2018 Jun 1;66(12):1899-1909. doi: 10.1093/cid/cix1124.

21.

Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration.

Scott G, Zetterberg H, Jolly A, Cole JH, De Simoni S, Jenkins PO, Feeney C, Owen DR, Lingford-Hughes A, Howes O, Patel MC, Goldstone AP, Gunn RN, Blennow K, Matthews PM, Sharp DJ.

Brain. 2018 Feb 1;141(2):459-471. doi: 10.1093/brain/awx339.

22.

Altered caudate connectivity is associated with executive dysfunction after traumatic brain injury.

De Simoni S, Jenkins PO, Bourke NJ, Fleminger JJ, Hellyer PJ, Jolly AE, Patel MC, Cole JH, Leech R, Sharp DJ.

Brain. 2018 Jan 1;141(1):148-164. doi: 10.1093/brain/awx309.

23.

Spatiotemporal Distribution of β-Amyloid in Alzheimer Disease Is the Result of Heterogeneous Regional Carrying Capacities.

Whittington A, Sharp DJ, Gunn RN; Alzheimer’s Disease Neuroimaging Initiative.

J Nucl Med. 2018 May;59(5):822-827. doi: 10.2967/jnumed.117.194720. Epub 2017 Nov 16.

24.

Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers.

van Zoest RA, Underwood J, De Francesco D, Sabin CA, Cole JH, Wit FW, Caan MWA, Kootstra NA, Fuchs D, Zetterberg H, Majoie CBLM, Portegies P, Winston A, Sharp DJ, Gisslén M, Reiss P; Comorbidity in Relation to AIDS (COBRA) Collaboration.

J Infect Dis. 2017 Dec 27;217(1):69-81. doi: 10.1093/infdis/jix553.

25.

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B.

Nat Commun. 2017 Sep 18;8(1):578. doi: 10.1038/s41467-017-00654-w.

26.

Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration.

Austin TO, Matamoros AJ, Friedman JM, Friedman AJ, Nacharaju P, Yu W, Sharp DJ, Baas PW.

Sci Rep. 2017 Aug 29;7(1):9675. doi: 10.1038/s41598-017-10250-z.

27.

Hearables: Multimodal physiological in-ear sensing.

Goverdovsky V, von Rosenberg W, Nakamura T, Looney D, Sharp DJ, Papavassiliou C, Morrell MJ, Mandic DP.

Sci Rep. 2017 Jul 31;7(1):6948. doi: 10.1038/s41598-017-06925-2.

28.

Relationships between the integrity and function of lumbar nerve roots as assessed by diffusion tensor imaging and neurophysiology.

Chiou SY, Hellyer PJ, Sharp DJ, Newbould RD, Patel MC, Strutton PH.

Neuroradiology. 2017 Sep;59(9):893-903. doi: 10.1007/s00234-017-1869-0. Epub 2017 Jul 25.

29.

Characteristics of children who do not attend their hospital appointments, and GPs' response: a mixed methods study in primary and secondary care.

French LR, Turner KM, Morley H, Goldsworthy L, Sharp DJ, Hamilton-Shield J.

Br J Gen Pract. 2017 Jul;67(660):e483-e489. doi: 10.3399/bjgp17X691373. Epub 2017 Jun 19.

30.

Serum insulin-like growth factor-I levels are associated with improved white matter recovery after traumatic brain injury.

Feeney C, Sharp DJ, Hellyer PJ, Jolly AE, Cole JH, Scott G, Baxter D, Jilka S, Ross E, Ham TE, Jenkins PO, Li LM, Gorgoraptis N, Midwinter M, Goldstone AP.

Ann Neurol. 2017 Jul;82(1):30-43. doi: 10.1002/ana.24971.

31.

The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure.

Renda F, Pellacani C, Strunov A, Bucciarelli E, Naim V, Bosso G, Kiseleva E, Bonaccorsi S, Sharp DJ, Khodjakov A, Gatti M, Somma MP.

PLoS Genet. 2017 May 15;13(5):e1006784. doi: 10.1371/journal.pgen.1006784. eCollection 2017 May.

32.

Acute hospital admission of the frail older person: an opportunity to discuss future care.

Pocock LV, Sharp DJ.

Age Ageing. 2017 Nov 1;46(6):878-879. doi: 10.1093/ageing/afx052. No abstract available.

PMID:
28444122
33.

Brain age predicts mortality.

Cole JH, Ritchie SJ, Bastin ME, Valdés Hernández MC, Muñoz Maniega S, Royle N, Corley J, Pattie A, Harris SE, Zhang Q, Wray NR, Redmond P, Marioni RE, Starr JM, Cox SR, Wardlaw JM, Sharp DJ, Deary IJ.

Mol Psychiatry. 2018 May;23(5):1385-1392. doi: 10.1038/mp.2017.62. Epub 2017 Apr 25.

34.

Gray and White Matter Abnormalities in Treated Human Immunodeficiency Virus Disease and Their Relationship to Cognitive Function.

Underwood J, Cole JH, Caan M, De Francesco D, Leech R, van Zoest RA, Su T, Geurtsen GJ, Schmand BA, Portegies P, Prins M, Wit FWNM, Sabin CA, Majoie C, Reiss P, Winston A, Sharp DJ; Comorbidity in Relation to AIDS (COBRA) Collaboration.

Clin Infect Dis. 2017 Aug 1;65(3):422-432. doi: 10.1093/cid/cix301.

35.

Externally induced frontoparietal synchronization modulates network dynamics and enhances working memory performance.

Violante IR, Li LM, Carmichael DW, Lorenz R, Leech R, Hampshire A, Rothwell JC, Sharp DJ.

Elife. 2017 Mar 14;6. pii: e22001. doi: 10.7554/eLife.22001.

36.

Increased brain-predicted aging in treated HIV disease.

Cole JH, Underwood J, Caan MW, De Francesco D, van Zoest RA, Leech R, Wit FW, Portegies P, Geurtsen GJ, Schmand BA, Schim van der Loeff MF, Franceschi C, Sabin CA, Majoie CB, Winston A, Reiss P, Sharp DJ; COBRA collaboration.

Neurology. 2017 Apr 4;88(14):1349-1357. doi: 10.1212/WNL.0000000000003790. Epub 2017 Mar 3. Erratum in: Neurology. 2017 Oct 10;89(15):1652.

37.

Patients with chronic dizziness following traumatic head injury typically have multiple diagnoses involving combined peripheral and central vestibular dysfunction.

Arshad Q, Roberts RE, Ahmad H, Lobo R, Patel M, Ham T, Sharp DJ, Seemungal BM.

Clin Neurol Neurosurg. 2017 Apr;155:17-19. doi: 10.1016/j.clineuro.2017.01.021. Epub 2017 Feb 7.

PMID:
28212927
38.

Cerebral blood flow and cognitive function in HIV-infected men with sustained suppressed viremia on combination antiretroviral therapy.

Su T, Mutsaerts HJ, Caan MW, Wit FW, Schouten J, Geurtsen GJ, Sharp DJ, Prins M, Richard E, Portegies P, Reiss P, Majoie CB; AGEhIV Cohort Study.

AIDS. 2017 Mar 27;31(6):847-856. doi: 10.1097/QAD.0000000000001414.

PMID:
28121708
39.

Computational modelling of traumatic brain injury predicts the location of chronic traumatic encephalopathy pathology.

Ghajari M, Hellyer PJ, Sharp DJ.

Brain. 2017 Feb;140(2):333-343. doi: 10.1093/brain/aww317. Epub 2017 Jan 2.

40.

Functional neuroimaging of visuo-vestibular interaction.

Roberts RE, Ahmad H, Arshad Q, Patel M, Dima D, Leech R, Seemungal BM, Sharp DJ, Bronstein AM.

Brain Struct Funct. 2017 Jul;222(5):2329-2343. doi: 10.1007/s00429-016-1344-4. Epub 2016 Dec 10.

41.

Disconnection between the default mode network and medial temporal lobes in post-traumatic amnesia.

De Simoni S, Grover PJ, Jenkins PO, Honeyfield L, Quest RA, Ross E, Scott G, Wilson MH, Majewska P, Waldman AD, Patel MC, Sharp DJ.

Brain. 2016 Dec;139(Pt 12):3137-3150. Epub 2016 Oct 22.

42.

Targeting Microtubules for Wound Repair.

Charafeddine RA, Nosanchuk JD, Sharp DJ.

Adv Wound Care (New Rochelle). 2016 Oct 1;5(10):444-454. Review.

43.

Long-Term Outcomes Associated with Traumatic Brain Injury in Childhood and Adolescence: A Nationwide Swedish Cohort Study of a Wide Range of Medical and Social Outcomes.

Sariaslan A, Sharp DJ, D'Onofrio BM, Larsson H, Fazel S.

PLoS Med. 2016 Aug 23;13(8):e1002103. doi: 10.1371/journal.pmed.1002103. eCollection 2016 Aug.

44.

Interictal activity is an important contributor to abnormal intrinsic network connectivity in paediatric focal epilepsy.

Shamshiri EA, Tierney TM, Centeno M, St Pier K, Pressler RM, Sharp DJ, Perani S, Cross JH, Carmichael DW.

Hum Brain Mapp. 2017 Jan;38(1):221-236. doi: 10.1002/hbm.23356. Epub 2016 Aug 20.

PMID:
27543883
45.

Cortical Entropy, Mutual Information and Scale-Free Dynamics in Waking Mice.

Fagerholm ED, Scott G, Shew WL, Song C, Leech R, Knöpfel T, Sharp DJ.

Cereb Cortex. 2016 Oct;26(10):3945-52. doi: 10.1093/cercor/bhw200. Epub 2016 Jul 6.

46.

Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain.

Feeney C, Scott G, Raffel J, Roberts S, Coello C, Jolly A, Searle G, Goldstone AP, Brooks DJ, Nicholas RS, Trigg W, Gunn RN, Sharp DJ.

Eur J Nucl Med Mol Imaging. 2016 Nov;43(12):2201-2210. Epub 2016 Jun 28.

47.

Catecholamines and cognition after traumatic brain injury.

Jenkins PO, Mehta MA, Sharp DJ.

Brain. 2016 Sep;139(Pt 9):2345-71. doi: 10.1093/brain/aww128. Epub 2016 Jun 2. Review.

48.

Novel Modeling of Task vs. Rest Brain State Predictability Using a Dynamic Time Warping Spectrum: Comparisons and Contrasts with Other Standard Measures of Brain Dynamics.

Dinov M, Lorenz R, Scott G, Sharp DJ, Fagerholm ED, Leech R.

Front Comput Neurosci. 2016 May 12;10:46. doi: 10.3389/fncom.2016.00046. eCollection 2016.

49.

White matter hyperintensities in relation to cognition in HIV-infected men with sustained suppressed viral load on combination antiretroviral therapy.

Su T, Wit FW, Caan MW, Schouten J, Prins M, Geurtsen GJ, Cole JH, Sharp DJ, Richard E, Reneman L, Portegies P, Reiss P, Majoie CB; AGEhIV Cohort Study.

AIDS. 2016 Sep 24;30(15):2329-39. doi: 10.1097/QAD.0000000000001133.

50.

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