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Comprehensive assessments of ecological states of Songhua River using chemical analysis and bivalves as bioindicators.

Zarykhta VV, Zhang Z, Kholodkevich SV, Kuznetsova TV, Sharov AN, Zhang Y, Sun K, Lv M, Feng Y.

Environ Sci Pollut Res Int. 2019 Sep 13. doi: 10.1007/s11356-019-06349-7. [Epub ahead of print]


A single-cell transcriptome atlas of the adult human retina.

Lukowski SW, Lo CY, Sharov AA, Nguyen Q, Fang L, Hung SS, Zhu L, Zhang T, Grünert U, Nguyen T, Senabouth A, Jabbari JS, Welby E, Sowden JC, Waugh HS, Mackey A, Pollock G, Lamb TD, Wang PY, Hewitt AW, Gillies MC, Powell JE, Wong RC.

EMBO J. 2019 Sep 16;38(18):e100811. doi: 10.15252/embj.2018100811. Epub 2019 Aug 22.


Cadmium-induced oxidative stress, histopathology, and transcriptome changes in the hepatopancreas of freshwater crayfish (Procambarus clarkii).

Zhang Y, Li Z, Kholodkevich S, Sharov A, Feng Y, Ren N, Sun K.

Sci Total Environ. 2019 May 20;666:944-955. doi: 10.1016/j.scitotenv.2019.02.159. Epub 2019 Feb 14.


Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila.

Lee SK, Xue Y, Shen W, Zhang Y, Joo Y, Ahmad M, Chinen M, Ding Y, Ku WL, De S, Lehrmann E, Becker KG, Lei EP, Zhao K, Zou S, Sharov A, Wang W.

Nat Commun. 2018 Nov 23;9(1):4946. doi: 10.1038/s41467-018-07101-4.


Ezh2 Regulates Activation-Induced CD8+ T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression.

Chen G, Subedi K, Chakraborty S, Sharov A, Lu J, Kim J, Mi X, Wersto R, Sung MH, Weng NP.

Front Immunol. 2018 Mar 26;9:549. doi: 10.3389/fimmu.2018.00549. eCollection 2018.


Composite Agency: Semiotics of Modularity and Guiding Interactions.

Sharov AA.

Biosemiotics. 2017 Jul;10(2):157-178. doi: 10.1007/s12304-017-9301-z. Epub 2017 Jul 27.


5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells.

Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY.

PLoS Genet. 2017 Sep 1;13(9):e1006966. doi: 10.1371/journal.pgen.1006966. eCollection 2017 Sep.


Controlling the near-infrared transparency of costal cartilage by impregnation with clearing agents and magnetite nanoparticles.

Alexandrovskaya Y, Sadovnikov K, Sharov A, Sherstneva A, Evtushenko E, Omelchenko A, Obrezkova M, Tuchin V, Lunin V, Sobol E.

J Biophotonics. 2018 Feb;11(2). doi: 10.1002/jbio.201700105. Epub 2017 Aug 29.


p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.

Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A.

J Invest Dermatol. 2017 Oct;137(10):2157-2167. doi: 10.1016/j.jid.2017.05.013. Epub 2017 Jun 6.


LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis.

Kim J, Noh JH, Lee SK, Munk R, Sharov A, Lehrmann E, Zhang Y, Wang W, Abdelmohsen K, Gorospe M.

Oncotarget. 2017 Jul 25;8(30):49409-49420. doi: 10.18632/oncotarget.17219.


miRNAs Are Required for Postinduction Stage Sweat Gland Development.

Cui CY, Piao Y, Campbell DP, Ishii R, Michel M, Sharov A, Schlessinger D.

J Invest Dermatol. 2017 Jul;137(7):1571-1574. doi: 10.1016/j.jid.2017.03.003. Epub 2017 Mar 9. No abstract available.


Evolutionary biosemiotics and multilevel construction networks.

Sharov AA.

Biosemiotics. 2016 Dec;9(3):399-416. doi: 10.1007/s12304-016-9269-0. Epub 2016 Aug 16.


Induction of specific neuron types by overexpression of single transcription factors.

Teratani-Ota Y, Yamamizu K, Piao Y, Sharova L, Amano M, Yu H, Schlessinger D, Ko MS, Sharov AA.

In Vitro Cell Dev Biol Anim. 2016 Oct;52(9):961-973. Epub 2016 Jun 1.


Comprehending the Semiosis of Evolution.

Sharov A, Maran T, Tønnessen M.

Biosemiotics. 2016 Apr;9(1):1-6. No abstract available.


Enriched retinal ganglion cells derived from human embryonic stem cells.

Gill KP, Hung SS, Sharov A, Lo CY, Needham K, Lidgerwood GE, Jackson S, Crombie DE, Nayagam BA, Cook AL, Hewitt AW, Pébay A, Wong RC.

Sci Rep. 2016 Aug 10;6:30552. doi: 10.1038/srep30552.


Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines.

Yamamizu K, Sharov AA, Piao Y, Amano M, Yu H, Nishiyama A, Dudekula DB, Schlessinger D, Ko MS.

Sci Rep. 2016 May 6;6:25667. doi: 10.1038/srep25667.


Emergence of undifferentiated colonies from mouse embryonic stem cells undergoing differentiation by retinoic acid treatment.

Sharova LV, Sharov AA, Piao Y, Stagg CA, Amano T, Qian Y, Dudekula D, Schlessinger D, Ko MS.

In Vitro Cell Dev Biol Anim. 2016 May;52(5):616-24. doi: 10.1007/s11626-016-0013-5. Epub 2016 Apr 29.


Coenzyme world model of the origin of life.

Sharov AA.

Biosystems. 2016 Jun;144:8-17. doi: 10.1016/j.biosystems.2016.03.003. Epub 2016 Mar 9. Review.


Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality.

Botchkarev VA, Sharov AA.

J Invest Dermatol. 2016 Mar;136(3):557-559. doi: 10.1016/j.jid.2015.10.068.


Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.

Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA.

J Cell Biol. 2016 Jan 4;212(1):77-89. doi: 10.1083/jcb.201506065. Epub 2015 Dec 28.


TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition.

Li HM, Hiroi T, Zhang Y, Shi A, Chen G, De S, Metter EJ, Wood WH 3rd, Sharov A, Milner JD, Becker KG, Zhan M, Weng NP.

J Leukoc Biol. 2016 Mar;99(3):505-13. doi: 10.1189/jlb.6A0215-071RR. Epub 2015 Sep 22.


Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells.

Akiyama T, Xin L, Oda M, Sharov AA, Amano M, Piao Y, Cadet JS, Dudekula DB, Qian Y, Wang W, Ko SB, Ko MS.

DNA Res. 2015 Oct;22(5):307-18. doi: 10.1093/dnares/dsv013. Epub 2015 Aug 31.


ExAtlas: An interactive online tool for meta-analysis of gene expression data.

Sharov AA, Schlessinger D, Ko MS.

J Bioinform Comput Biol. 2015 Dec;13(6):1550019. doi: 10.1142/S0219720015500195. Epub 2015 Jun 9.


Protosemiosis: agency with reduced representation capacity.

Sharov AA, Vehkavaara T.

Biosemiotics. 2015 Apr 1;8(1):103-123.


Patterns of evolution.

Igamberdiev AU, Sharov AA.

Biosystems. 2014 Sep;123:1-2. doi: 10.1016/j.biosystems.2014.09.006. Epub 2014 Oct 30. No abstract available.


MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.

Ahmed MI, Alam M, Emelianov VU, Poterlowicz K, Patel A, Sharov AA, Mardaryev AN, Botchkareva NV.

J Cell Biol. 2014 Nov 24;207(4):549-67. doi: 10.1083/jcb.201404001.


Inferring directions of evolution from patterns of variation: the legacy of Sergei Meyen.

Sharov AA, Igamberdiev AU.

Biosystems. 2014 Sep;123:67-73. doi: 10.1016/j.biosystems.2014.06.008. Epub 2014 Jul 27.


Evolutionary constraints or opportunities?

Sharov AA.

Biosystems. 2014 Sep;123:9-18. doi: 10.1016/j.biosystems.2014.06.004. Epub 2014 Jul 16.


The Epigenetic Regulation of Wound Healing.

Lewis CJ, Mardaryev AN, Sharov AA, Fessing MY, Botchkarev VA.

Adv Wound Care (New Rochelle). 2014 Jul 1;3(7):468-475. Review.


Complex changes in the apoptotic and cell differentiation programs during initiation of the hair follicle response to chemotherapy.

Sharova TY, Poterlowicz K, Botchkareva NV, Kondratiev NA, Aziz A, Spiegel JH, Botchkarev VA, Sharov AA.

J Invest Dermatol. 2014 Dec;134(12):2873-2882. doi: 10.1038/jid.2014.267. Epub 2014 Jul 7.


Chromatin properties of regulatory DNA probed by manipulation of transcription factors.

Sharov AA, Nishiyama A, Qian Y, Dudekula DB, Longo DL, Schlessinger D, Ko MS.

J Comput Biol. 2014 Aug;21(8):569-77. doi: 10.1089/cmb.2013.0126. Epub 2014 Jun 11.


Evolutionary constraints or opportunities?

Sharov AA.

Biosystems. 2014 Apr 22;120C:21-30. doi: 10.1016/j.biosystems.2014.04.005. [Epub ahead of print]


Identification of transcription factors for lineage-specific ESC differentiation.

Yamamizu K, Piao Y, Sharov AA, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko MS.

Stem Cell Reports. 2013 Nov 27;1(6):545-59. doi: 10.1016/j.stemcr.2013.10.006. eCollection 2013.


p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells.

Mardaryev AN, Gdula MR, Yarker JL, Emelianov VU, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Joffe B, Solovei I, Chambon P, Botchkarev VA, Fessing MY.

Development. 2014 Jan;141(1):101-11. doi: 10.1242/dev.103200. Erratum in: Development. 2014 Sep;141(17):3437. Joffe, Boris [added]; Solovei, Irina [added]; Emelianov, Vladimir N [corrected to Emelianov, Vladimir U].


A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance.

Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S, Bradley M, Nichols J, Ko MSH, Brickman JM.

Curr Biol. 2013 Nov 18;23(22):2233-2244. doi: 10.1016/j.cub.2013.09.048. Epub 2013 Nov 7.


Bone morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration.

Lewis CJ, Mardaryev AN, Poterlowicz K, Sharova TY, Aziz A, Sharpe DT, Botchkareva NV, Sharov AA.

J Invest Dermatol. 2014 Mar;134(3):827-837. doi: 10.1038/jid.2013.419. Epub 2013 Oct 14.


Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.

Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D 3rd, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W.

Nat Neurosci. 2013 Sep;16(9):1238-47. doi: 10.1038/nn.3479. Epub 2013 Aug 4.


Totipotent embryonic stem cells arise in ground-state culture conditions.

Morgani SM, Canham MA, Nichols J, Sharov AA, Migueles RP, Ko MS, Brickman JM.

Cell Rep. 2013 Jun 27;3(6):1945-57. doi: 10.1016/j.celrep.2013.04.034. Epub 2013 Jun 6.


Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells.

Hung SS, Wong RC, Sharov AA, Nakatake Y, Yu H, Ko MS.

DNA Res. 2013 Aug;20(4):391-402. doi: 10.1093/dnares/dst018. Epub 2013 May 5.


Systematic repression of transcription factors reveals limited patterns of gene expression changes in ES cells.

Nishiyama A, Sharov AA, Piao Y, Amano M, Amano T, Hoang HG, Binder BY, Tapnio R, Bassey U, Malinou JN, Correa-Cerro LS, Yu H, Xin L, Meyers E, Zalzman M, Nakatake Y, Stagg C, Sharova L, Qian Y, Dudekula D, Sheer S, Cadet JS, Hirata T, Yang HT, Goldberg I, Evans MK, Longo DL, Schlessinger D, Ko MS.

Sci Rep. 2013;3:1390. doi: 10.1038/srep01390.


Remodeling of three-dimensional organization of the nucleus during terminal keratinocyte differentiation in the epidermis.

Gdula MR, Poterlowicz K, Mardaryev AN, Sharov AA, Peng Y, Fessing MY, Botchkarev VA.

J Invest Dermatol. 2013 Sep;133(9):2191-201. doi: 10.1038/jid.2013.66. Epub 2013 Feb 13.


Pathobiology of chemotherapy-induced hair loss.

Paus R, Haslam IS, Sharov AA, Botchkarev VA.

Lancet Oncol. 2013 Feb;14(2):e50-9. doi: 10.1016/S1470-2045(12)70553-3. Review.


Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.

Vetter I, Touska F, Hess A, Hinsbey R, Sattler S, Lampert A, Sergejeva M, Sharov A, Collins LS, Eberhardt M, Engel M, Cabot PJ, Wood JN, Vlachová V, Reeh PW, Lewis RJ, Zimmermann K.

EMBO J. 2012 Oct 3;31(19):3795-808. doi: 10.1038/emboj.2012.207. Epub 2012 Jul 31.


Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MS, Ptashne M, Brickman JM.

Cell Rep. 2012 Feb 23;1(2):99-109. doi: 10.1016/j.celrep.2011.12.002. Epub 2012 Feb 16.


Epigenetic regulation of gene expression in keratinocytes.

Botchkarev VA, Gdula MR, Mardaryev AN, Sharov AA, Fessing MY.

J Invest Dermatol. 2012 Nov;132(11):2505-21. doi: 10.1038/jid.2012.182. Epub 2012 Jul 5. Review.


Topical application of thymidine dinucleotide to newborn mice reduces and delays development of UV-induced melanomas.

Goukassian DA, Sharov A, Rhodes J, Coleman C, Eller MS, Sharova T, Bhawan J, Gilchrest BA.

J Invest Dermatol. 2012 Nov;132(11):2664-6. doi: 10.1038/jid.2012.176. Epub 2012 Jun 14. No abstract available.


Generation of mouse ES cell lines engineered for the forced induction of transcription factors.

Correa-Cerro LS, Piao Y, Sharov AA, Nishiyama A, Cadet JS, Yu H, Sharova LV, Xin L, Hoang HG, Thomas M, Qian Y, Dudekula DB, Meyers E, Binder BY, Mowrer G, Bassey U, Longo DL, Schlessinger D, Ko MS.

Sci Rep. 2011;1:167. doi: 10.1038/srep00167. Epub 2011 Nov 23.


Modification of water ecosystems during and after the reduction of anthropogenic pollution.

Moiseenko TI, Sharov AN.

Dokl Biol Sci. 2011 Nov-Dec;441:389-92. doi: 10.1134/S0012496611060111. Epub 2012 Jan 7. No abstract available.


Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.

Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y.

Science. 2011 Dec 23;334(6063):1706-10. doi: 10.1126/science.1211222. Epub 2011 Nov 24.

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