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Items: 42


Kaposi's Sarcoma Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells.

Valiya Veettil M, Krishna G, Roy A, Ghosh A, Dutta D, Kumar B, Chakraborty S, Raveendran AT, Sharma-Walia N, Chandran B.

J Virol. 2020 Jan 22. pii: JVI.01692-19. doi: 10.1128/JVI.01692-19. [Epub ahead of print]


Arachidonic Acid Derived Lipid Mediators Influence Kaposi's Sarcoma-Associated Herpesvirus Infection and Pathogenesis.

Chandrasekharan JA, Sharma-Walia N.

Front Microbiol. 2019 Mar 12;10:358. doi: 10.3389/fmicb.2019.00358. eCollection 2019. Review.


HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity.

Kumar B, Roy A, Asha K, Sharma-Walia N, Ansari MA, Chandran B.

J Virol. 2019 Apr 17;93(9). pii: e01812-18. doi: 10.1128/JVI.01812-18. Print 2019 May 1.


Curbing Lipids: Impacts ON Cancer and Viral Infection.

Dutta A, Sharma-Walia N.

Int J Mol Sci. 2019 Feb 2;20(3). pii: E644. doi: 10.3390/ijms20030644. Review.


Water transport proteins-aquaporins (AQPs) in cancer biology.

Dajani S, Saripalli A, Sharma-Walia N.

Oncotarget. 2018 Nov 20;9(91):36392-36405. doi: 10.18632/oncotarget.26351. eCollection 2018 Nov 20. Review.


Virus and tumor microenvironment induced ER stress and unfolded protein response: from complexity to therapeutics.

Asha K, Sharma-Walia N.

Oncotarget. 2018 Aug 7;9(61):31920-31936. doi: 10.18632/oncotarget.25886. eCollection 2018 Aug 7. Review.


Fatty acid synthase regulates the pathogenicity of Th17 cells.

Young KE, Flaherty S, Woodman KM, Sharma-Walia N, Reynolds JM.

J Leukoc Biol. 2017 Nov;102(5):1229-1235. doi: 10.1189/jlb.3AB0417-159RR. Epub 2017 Aug 28.


Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis.

Chandrasekharan JA, Huang XM, Hwang AC, Sharma-Walia N.

J Virol. 2016 Nov 28;90(24):11020-11031. Print 2016 Dec 15.


An insight into the role of arachidonic acid derived lipid mediators in virus associated pathogenesis and malignancies.

Chandrasekharan JA, Marginean A, Sharma-Walia N.

Prostaglandins Other Lipid Mediat. 2016 Nov;126:46-54. doi: 10.1016/j.prostaglandins.2016.07.009. Epub 2016 Jul 20. Review.


Osteoprotegerin rich tumor microenvironment: implications in breast cancer.

Goswami S, Sharma-Walia N.

Oncotarget. 2016 Jul 5;7(27):42777-42791. doi: 10.18632/oncotarget.8658. Review.


Implications of a peroxisome proliferator-activated receptor alpha (PPARĪ±) ligand clofibrate in breast cancer.

Chandran K, Goswami S, Sharma-Walia N.

Oncotarget. 2016 Mar 29;7(13):15577-99. doi: 10.18632/oncotarget.6402.


Lipoxins: nature's way to resolve inflammation.

Chandrasekharan JA, Sharma-Walia N.

J Inflamm Res. 2015 Sep 30;8:181-92. doi: 10.2147/JIR.S90380. eCollection 2015. Review.


Lipoxins exert antiangiogenic and anti-inflammatory effects on Kaposi's sarcoma cells.

Marginean A, Sharma-Walia N.

Transl Res. 2015 Aug;166(2):111-33. doi: 10.1016/j.trsl.2015.02.009. Epub 2015 Mar 6.


Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.

Valiya Veettil M, Dutta D, Bottero V, Bandyopadhyay C, Gjyshi O, Sharma-Walia N, Dutta S, Chandran B.

PLoS Pathog. 2014 Oct 9;10(10):e1004389. doi: 10.1371/journal.ppat.1004389. eCollection 2014 Oct.


The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis.

Sharma-Walia N, Chandran K, Patel K, Veettil MV, Marginean A.

J Virol. 2014 Feb;88(4):2131-56. doi: 10.1128/JVI.02786-13. Epub 2013 Dec 11. Erratum in: J Virol. 2014 May;88(9):5206.


Cyclooxygenase-2-prostaglandin E2-eicosanoid receptor inflammatory axis: a key player in Kaposi's sarcoma-associated herpes virus associated malignancies.

Paul AG, Chandran B, Sharma-Walia N.

Transl Res. 2013 Aug;162(2):77-92. doi: 10.1016/j.trsl.2013.03.004. Epub 2013 Apr 6. Review.


Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival.

Sadagopan S, Veettil MV, Chakraborty S, Sharma-Walia N, Paudel N, Bottero V, Chandran B.

Oncogene. 2012 Nov 15;31(46):4835-47. doi: 10.1038/onc.2011.648. Epub 2012 Jan 23.


COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP.

Sharma-Walia N, Patel K, Chandran K, Marginean A, Bottero V, Kerur N, Paul AG.

Oncogenesis. 2012 Apr 2;1:e5. doi: 10.1038/oncsis.2012.5.


Targeting KSHV/HHV-8 latency with COX-2 selective inhibitor nimesulide: a potential chemotherapeutic modality for primary effusion lymphoma.

Paul AG, Sharma-Walia N, Chandran B.

PLoS One. 2011;6(9):e24379. doi: 10.1371/journal.pone.0024379. Epub 2011 Sep 30.


IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.

Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B.

Cell Host Microbe. 2011 May 19;9(5):363-75. doi: 10.1016/j.chom.2011.04.008.


Phosphorylation and polyubiquitination of transforming growth factor beta-activated kinase 1 are necessary for activation of NF-kappaB by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.

Bottero V, Kerur N, Sadagopan S, Patel K, Sharma-Walia N, Chandran B.

J Virol. 2011 Mar;85(5):1980-93. doi: 10.1128/JVI.01911-10. Epub 2010 Dec 15.


NFAT and CREB regulate Kaposi's sarcoma-associated herpesvirus-induced cyclooxygenase 2 (COX-2).

Sharma-Walia N, George Paul A, Patel K, Chandran K, Ahmad W, Chandran B.

J Virol. 2010 Dec;84(24):12733-53. doi: 10.1128/JVI.01065-10. Epub 2010 Oct 13.


Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling.

Kerur N, Veettil MV, Sharma-Walia N, Sadagopan S, Bottero V, Paul AG, Chandran B.

Virology. 2010 Oct 10;406(1):103-16. doi: 10.1016/j.virol.2010.07.012. Epub 2010 Aug 1.


Piracy of prostaglandin E2/EP receptor-mediated signaling by Kaposi's sarcoma-associated herpes virus (HHV-8) for latency gene expression: strategy of a successful pathogen.

George Paul A, Sharma-Walia N, Kerur N, White C, Chandran B.

Cancer Res. 2010 May 1;70(9):3697-708. doi: 10.1158/0008-5472.CAN-09-3934. Epub 2010 Apr 13.


Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion.

Sharma-Walia N, Paul AG, Bottero V, Sadagopan S, Veettil MV, Kerur N, Chandran B.

PLoS Pathog. 2010 Feb 12;6(2):e1000777. doi: 10.1371/journal.ppat.1000777.


Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression.

Bottero V, Sharma-Walia N, Kerur N, Paul AG, Sadagopan S, Cannon M, Chandran B.

Virology. 2009 Sep 15;392(1):34-51. doi: 10.1016/j.virol.2009.07.002. Epub 2009 Jul 28.


Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells.

Raghu H, Sharma-Walia N, Veettil MV, Sadagopan S, Chandran B.

J Virol. 2009 May;83(10):4895-911. doi: 10.1128/JVI.02498-08. Epub 2009 Mar 11.


Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis.

Sadagopan S, Sharma-Walia N, Veettil MV, Bottero V, Levine R, Vart RJ, Chandran B.

J Virol. 2009 Apr;83(7):3342-64. doi: 10.1128/JVI.02052-08. Epub 2009 Jan 21.


Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implications.

Sivakumar R, Sharma-Walia N, Raghu H, Veettil MV, Sadagopan S, Bottero V, Varga L, Levine R, Chandran B.

J Virol. 2008 Feb;82(4):1759-76. Epub 2007 Dec 5.


RhoA-GTPase facilitates entry of Kaposi's sarcoma-associated herpesvirus into adherent target cells in a Src-dependent manner.

Veettil MV, Sharma-Walia N, Sadagopan S, Raghu H, Sivakumar R, Naranatt PP, Chandran B.

J Virol. 2006 Dec;80(23):11432-46. Epub 2006 Sep 27.


Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression.

Sharma-Walia N, Raghu H, Sadagopan S, Sivakumar R, Veettil MV, Naranatt PP, Smith MM, Chandran B.

J Virol. 2006 Jul;80(13):6534-52.


Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells.

Krishnan HH, Sharma-Walia N, Streblow DN, Naranatt PP, Chandran B.

J Virol. 2006 Feb;80(3):1167-80.


Envelope glycoprotein gB of Kaposi's sarcoma-associated herpesvirus is essential for egress from infected cells.

Krishnan HH, Sharma-Walia N, Zeng L, Gao SJ, Chandran B.

J Virol. 2005 Sep;79(17):10952-67.


Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence.

Wang FZ, Akula SM, Sharma-Walia N, Zeng L, Chandran B.

J Virol. 2003 Mar;77(5):3131-47.

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