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Items: 1 to 50 of 214

1.

Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells.

Thomson GJ, Hernon C, Austriaco N, Shapiro RS, Belenky P, Bennett RJ.

EMBO J. 2019 Aug 26:e101597. doi: 10.15252/embj.2019101597. [Epub ahead of print]

PMID:
31448850
2.

mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens.

Shapiro RS.

mSphere. 2019 Jun 26;4(3). pii: e00313-19. doi: 10.1128/mSphere.00313-19.

3.

Author Correction: Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans.

Halder V, Porter CBM, Chavez A, Shapiro RS.

Nat Protoc. 2019 Aug;14(8):2595. doi: 10.1038/s41596-019-0157-3.

PMID:
30976123
4.

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens.

Sharma J, Rosiana S, Razzaq I, Shapiro RS.

J Fungi (Basel). 2019 Feb 21;5(1). pii: E17. doi: 10.3390/jof5010017. Review.

5.

A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans.

Wensing L, Sharma J, Uthayakumar D, Proteau Y, Chavez A, Shapiro RS.

mSphere. 2019 Feb 13;4(1). pii: e00002-19. doi: 10.1128/mSphere.00002-19.

6.

Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans.

Halder V, Porter CBM, Chavez A, Shapiro RS.

Nat Protoc. 2019 Mar;14(3):955-975. doi: 10.1038/s41596-018-0122-6. Epub 2019 Feb 8. Erratum in: Nat Protoc. 2019 Aug;14(8):2595.

PMID:
30737491
7.

An essential role for the Zn2+ transporter ZIP7 in B cell development.

Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S.

Nat Immunol. 2019 Mar;20(3):350-361. doi: 10.1038/s41590-018-0295-8. Epub 2019 Feb 4.

8.

Functional divergence of a global regulatory complex governing fungal filamentation.

Polvi EJ, Veri AO, Liu Z, Hossain S, Hyde S, Kim SH, Tebbji F, Sellam A, Todd RT, Xie JL, Lin ZY, Wong CJ, Shapiro RS, Whiteway M, Robbins N, Gingras AC, Selmecki A, Cowen LE.

PLoS Genet. 2019 Jan 7;15(1):e1007901. doi: 10.1371/journal.pgen.1007901. eCollection 2019 Jan.

9.

Microscale Biosignatures and Abiotic Mineral Authigenesis in Little Hot Creek, California.

Kraus EA, Beeler SR, Mors RA, Floyd JG; GeoBiology 2016, Stamps BW, Nunn HS, Stevenson BS, Johnson HA, Shapiro RS, Loyd SJ, Spear JR, Corsetti FA.

Front Microbiol. 2018 May 25;9:997. doi: 10.3389/fmicb.2018.00997. eCollection 2018.

10.

New pathogens, new tricks: emerging, drug-resistant fungal pathogens and future prospects for antifungal therapeutics.

Geddes-McAlister J, Shapiro RS.

Ann N Y Acad Sci. 2019 Jan;1435(1):57-78. doi: 10.1111/nyas.13739. Epub 2018 May 15. Review.

PMID:
29762860
11.

CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms.

Shapiro RS, Chavez A, Collins JJ.

Nat Rev Microbiol. 2018 Jun;16(6):333-339. doi: 10.1038/s41579-018-0002-7. Review.

PMID:
29599458
12.

Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.

Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE.

PLoS Genet. 2018 Mar 28;14(3):e1007270. doi: 10.1371/journal.pgen.1007270. eCollection 2018 Mar.

13.

Precise Cas9 targeting enables genomic mutation prevention.

Chavez A, Pruitt BW, Tuttle M, Shapiro RS, Cecchi RJ, Winston J, Turczyk BM, Tung M, Collins JJ, Church GM.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3669-3673. doi: 10.1073/pnas.1718148115. Epub 2018 Mar 19.

14.

Lack of Benefit of Heliox During Mechanical Ventilation of Subjects With Severe Air-Flow Obstruction.

Leatherman JW, Romero RS, Shapiro RS.

Respir Care. 2018 Apr;63(4):375-379. doi: 10.4187/respcare.05893. Epub 2017 Dec 26.

15.

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans.

Shapiro RS, Chavez A, Porter CBM, Hamblin M, Kaas CS, DiCarlo JE, Zeng G, Xu X, Revtovich AV, Kirienko NV, Wang Y, Church GM, Collins JJ.

Nat Microbiol. 2018 Jan;3(1):73-82. doi: 10.1038/s41564-017-0043-0. Epub 2017 Oct 23.

16.

Reconciling States' "Right to Try" Legislation and FDA's Expanded Access Program: Legal Issues.

Shapiro RS.

Ther Innov Regul Sci. 2017 Mar;51(2):153-156. doi: 10.1177/2168479016683217. Epub 2017 Jan 5.

PMID:
30231723
17.

Case Studies.

Shapiro RS, Wasserman RL, Bonagura V, Gupta S.

J Clin Immunol. 2017 Feb;37(2):188-189. doi: 10.1007/s10875-013-9929-7. Epub 2013 Aug 20. No abstract available.

PMID:
28236086
18.

Supplement: Frontiers in Immunoglobulin Therapy of Primary Immunodeficiency Disease.

Shapiro RS.

J Clin Immunol. 2017 Feb;37(2):187. doi: 10.1007/s10875-013-9914-1. Epub 2013 Jun 25. No abstract available.

PMID:
28236085
19.

A role for the bacterial GATC methylome in antibiotic stress survival.

Cohen NR, Ross CA, Jain S, Shapiro RS, Gutierrez A, Belenky P, Li H, Collins JJ.

Nat Genet. 2016 May;48(5):581-6. doi: 10.1038/ng.3530. Epub 2016 Mar 21.

20.

Low levels of IGFBP7 expression in high-grade serous ovarian carcinoma is associated with patient outcome.

Gambaro K, Quinn MC, Cáceres-Gorriti KY, Shapiro RS, Provencher D, Rahimi K, Mes-Masson AM, Tonin PN.

BMC Cancer. 2015 Mar 17;15:135. doi: 10.1186/s12885-015-1138-8.

21.

Antimicrobial-induced DNA damage and genomic instability in microbial pathogens.

Shapiro RS.

PLoS Pathog. 2015 Mar 26;11(3):e1004678. doi: 10.1371/journal.ppat.1004678. eCollection 2015 Mar. Review. No abstract available.

22.

Hematite-coated microfossils: primary ecological fingerprint or taphonomic oddity of the Paleoproterozoic?

Shapiro RS, Konhauser KO.

Geobiology. 2015 May;13(3):209-24. doi: 10.1111/gbi.12127. Epub 2015 Feb 2.

PMID:
25639940
23.

Facilitating home-based treatment of hereditary angioedema.

Bernstein JA, Riedl M, Zacek L, Shapiro RS.

Allergy Asthma Proc. 2015 Mar-Apr;36(2):92-9. doi: 10.2500/aap.2015.36.3820. Epub 2014 Dec 30. Review.

PMID:
25551795
24.

7th International Immunoglobulin Conference: Immunoglobulin in clinical practice.

Shapiro RS, Borte M.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:86. doi: 10.1111/cei.12522.

25.

7th International Immunoglobulin Conference: Immunoglobulin in clinical practice.

Shapiro RS, Borte M.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:65-6. doi: 10.1111/cei.12515. Review.

26.

Training hereditary angioedema patients to self-administer intravenous C1 esterase inhibitor concentrate.

Shapiro RS, Zacek L.

J Infus Nurs. 2014 Jul-Aug;37(4):284-90. doi: 10.1097/NAN.0000000000000049.

PMID:
24983261
27.

Emerging Paradigm of Primary Immunodeficiency Disease: Individualizing Immunoglobulin Dose and Delivery to Enhance Outcomes.

Shapiro RS, Wasserman RL, Bonagura V, Gupta S.

J Clin Immunol. 2017 Feb;37(2):190-196. doi: 10.1007/s10875-014-9990-x. Epub 2014 Jan 30. Review.

PMID:
24477950
28.

The effect of caffeine on hearing in a guinea pig model of acoustic trauma.

Mujica-Mota MA, Gasbarrino K, Rappaport JM, Shapiro RS, Daniel SJ.

Am J Otolaryngol. 2014 Mar-Apr;35(2):99-105. doi: 10.1016/j.amjoto.2013.11.009. Epub 2013 Dec 7.

PMID:
24406118
29.

Subcutaneous immunoglobulin therapy given by subcutaneous rapid push vs infusion pump: a retrospective analysis.

Shapiro RS.

Ann Allergy Asthma Immunol. 2013 Jul;111(1):51-5. doi: 10.1016/j.anai.2013.04.015. Epub 2013 May 22.

PMID:
23806460
30.

Microbial biogeochemistry of Boiling Springs Lake: a physically dynamic, oligotrophic, low-pH geothermal ecosystem.

Siering PL, Wolfe GV, Wilson MS, Yip AN, Carey CM, Wardman CD, Shapiro RS, Stedman KM, Kyle J, Yuan T, Van Nostrand JD, He Z, Zhou J.

Geobiology. 2013 Jul;11(4):356-76. doi: 10.1111/gbi.12041. Epub 2013 May 17.

PMID:
23679065
31.

Subcutaneous immunoglobulin: rapid push vs. infusion pump in pediatrics.

Shapiro RS.

Pediatr Allergy Immunol. 2013 Feb;24(1):49-53. doi: 10.1111/pai.12026.

PMID:
23331529
32.

Why I use subcutaneous immunoglobulin (SCIG).

Shapiro RS.

J Clin Immunol. 2013 Jan;33 Suppl 2:S95-8. doi: 10.1007/s10875-012-9853-2. Epub 2012 Dec 21. Review.

PMID:
23264027
33.

Clinical ambiguities--ongoing questions.

Torgerson TR, Bonagura VR, Shapiro RS.

J Clin Immunol. 2013 Jan;33 Suppl 2:S99-103. doi: 10.1007/s10875-012-9851-4. Epub 2012 Dec 16.

PMID:
23242829
34.
35.

Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans.

Shapiro RS, Ryan O, Boone C, Cowen LE.

Cell Cycle. 2012 Dec 1;11(23):4294-5. doi: 10.4161/cc.22608. Epub 2012 Oct 24. No abstract available.

36.

Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing.

Shapiro RS, Cowen LE.

MBio. 2012 Oct 2;3(5). pii: e00238-12. doi: 10.1128/mBio.00238-12. Print 2012. Review.

37.

Global gene deletion analysis exploring yeast filamentous growth.

Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, Schwarzmüller T, Reynolds TB, Kuchler K, Gifford DK, Whiteway M, Giaever G, Nislow C, Costanzo M, Gingras AC, Mitra RD, Andrews B, Fink GR, Cowen LE, Boone C.

Science. 2012 Sep 14;337(6100):1353-6. doi: 10.1126/science.1224339.

38.

The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance.

Shapiro RS, Zaas AK, Betancourt-Quiroz M, Perfect JR, Cowen LE.

PLoS One. 2012;7(9):e44734. doi: 10.1371/journal.pone.0044734. Epub 2012 Sep 6.

39.

Payor issues: barriers to optimal management of patients with primary immunodeficiency.

Shapiro RS, Boyle M.

J Clin Immunol. 2012 Sep;32 Suppl 2:S410-4. Epub 2012 Aug 25.

PMID:
22918575
40.

Local and national advocacy support.

Shapiro RS, Boyle M, Perez EE.

J Clin Immunol. 2012 Sep;32 Suppl 2:S423-6. Epub 2012 Jul 19. Review.

41.

Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis.

Shapiro RS, Cowen LE.

Virulence. 2012 Jul 1;3(4):400-4. doi: 10.4161/viru.20979. Epub 2012 Jun 22. Review.

42.

Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry.

Diezmann S, Michaut M, Shapiro RS, Bader GD, Cowen LE.

PLoS Genet. 2012;8(3):e1002562. doi: 10.1371/journal.pgen.1002562. Epub 2012 Mar 15.

43.

Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise.

Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE.

Curr Biol. 2012 Mar 20;22(6):461-70. doi: 10.1016/j.cub.2012.01.062. Epub 2012 Feb 23.

44.

Use of expiratory change in bladder pressure to assess expiratory muscle activity in patients with large respiratory excursions in central venous pressure.

Leatherman JW, Bastin-Dejong C, Shapiro RS, Saavedra-Romero R.

Intensive Care Med. 2012 Mar;38(3):453-7. doi: 10.1007/s00134-011-2450-7. Epub 2012 Jan 10.

PMID:
22231173
45.

Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans.

Senn H, Shapiro RS, Cowen LE.

Mol Biol Cell. 2012 Jan;23(2):268-83. doi: 10.1091/mbc.E11-08-0729. Epub 2011 Nov 16.

46.

Regulatory circuitry governing fungal development, drug resistance, and disease.

Shapiro RS, Robbins N, Cowen LE.

Microbiol Mol Biol Rev. 2011 Jun;75(2):213-67. doi: 10.1128/MMBR.00045-10. Review.

47.

Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans.

Shapiro RS, Cowen L.

Virulence. 2010 Jan-Feb;1(1):45-8. doi: 10.4161/viru.1.1.10320. Review.

48.

Malignancies in the setting of primary immunodeficiency: Implications for hematologists/oncologists.

Shapiro RS.

Am J Hematol. 2011 Jan;86(1):48-55. doi: 10.1002/ajh.21903. Review.

49.

Subcutaneous immunoglobulin: opportunities and outlook.

Misbah S, Sturzenegger MH, Borte M, Shapiro RS, Wasserman RL, Berger M, Ochs HD.

Clin Exp Immunol. 2009 Dec;158 Suppl 1:51-9. doi: 10.1111/j.1365-2249.2009.04027.x. Review.

50.

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling.

Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, Heitman J, Cowen LE.

Curr Biol. 2009 Apr 28;19(8):621-9. doi: 10.1016/j.cub.2009.03.017. Epub 2009 Mar 26.

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