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Items: 1 to 50 of 73

1.

The innate immune response to ischemic injury: a multiscale modeling perspective.

Dimitrova E, Caromile LA, Laubenbacher R, Shapiro LH.

BMC Syst Biol. 2018 Apr 10;12(1):50. doi: 10.1186/s12918-018-0580-z.

2.

Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction.

Ghosh M, Thangada S, Dasgupta O, Khanna KM, Yamase HT, Kashgarian M, Hla T, Shapiro LH, Ferrer FA.

PLoS One. 2018 Mar 8;13(3):e0194053. doi: 10.1371/journal.pone.0194053. eCollection 2018.

3.

PSMA redirects MAPK to PI3K-AKT signaling to promote prostate cancer progression.

Caromile LA, Shapiro LH.

Mol Cell Oncol. 2017 Apr 28;4(4):e1321168. doi: 10.1080/23723556.2017.1321168. eCollection 2017.

4.

PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer.

Caromile LA, Dortche K, Rahman MM, Grant CL, Stoddard C, Ferrer FA, Shapiro LH.

Sci Signal. 2017 Mar 14;10(470). pii: eaag3326. doi: 10.1126/scisignal.aag3326.

5.

Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide.

Conway RE, Rojas C, Alt J, Nováková Z, Richardson SM, Rodrick TC, Fuentes JL, Richardson NH, Attalla J, Stewart S, Fahmy B, Barinka C, Ghosh M, Shapiro LH, Slusher BS.

Angiogenesis. 2016 Oct;19(4):487-500. doi: 10.1007/s10456-016-9521-x. Epub 2016 Jul 8.

PMID:
27387982
6.

Proximal tubule proteins are significantly elevated in bladder urine of patients with ureteropelvic junction obstruction and may represent novel biomarkers: A pilot study.

Gerber C, Harel M, Lynch ML, Herbst KW, Ferrer FA, Shapiro LH.

J Pediatr Urol. 2016 Apr;12(2):120.e1-7. doi: 10.1016/j.jpurol.2015.10.008. Epub 2015 Nov 28.

PMID:
26705690
7.

Future directions in risk stratification and therapy for advanced pediatric genitourinary rhabdomyosarcoma.

Harel M, Ferrer FA, Shapiro LH, Makari JH.

Urol Oncol. 2016 Feb;34(2):103-15. doi: 10.1016/j.urolonc.2015.09.013. Epub 2015 Oct 28. Review.

PMID:
26519985
8.

Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.

Li MH, Swenson R, Harel M, Jana S, Stolarzewicz E, Hla T, Shapiro LH, Ferrer F.

J Pharmacol Exp Ther. 2015 Sep;354(3):261-8. doi: 10.1124/jpet.115.224519. Epub 2015 Jun 23.

9.

CD13 restricts TLR4 endocytic signal transduction in inflammation.

Ghosh M, Subramani J, Rahman MM, Shapiro LH.

J Immunol. 2015 May 1;194(9):4466-76. doi: 10.4049/jimmunol.1403133. Epub 2015 Mar 23.

10.

Treatment with the immunomodulator FTY720 (fingolimod) significantly reduces renal inflammation in murine unilateral ureteral obstruction.

Thangada S, Shapiro LH, Silva C, Yamase H, Hla T, Ferrer FA.

J Urol. 2014 May;191(5 Suppl):1508-16. doi: 10.1016/j.juro.2013.10.072. Epub 2014 Mar 26.

PMID:
24679864
11.

Molecular mechanisms regulating CD13-mediated adhesion.

Ghosh M, Gerber C, Rahman MM, Vernier KM, Pereira FE, Subramani J, Caromile LA, Shapiro LH.

Immunology. 2014 Aug;142(4):636-47. doi: 10.1111/imm.12279.

12.

CD13 promotes mesenchymal stem cell-mediated regeneration of ischemic muscle.

Rahman MM, Subramani J, Ghosh M, Denninger JK, Takeda K, Fong GH, Carlson ME, Shapiro LH.

Front Physiol. 2014 Jan 9;4:402. doi: 10.3389/fphys.2013.00402. eCollection 2014.

13.

CD13 regulates anchorage and differentiation of the skeletal muscle satellite stem cell population in ischemic injury.

Rahman MM, Ghosh M, Subramani J, Fong GH, Carlson ME, Shapiro LH.

Stem Cells. 2014 Jun;32(6):1564-77. doi: 10.1002/stem.1610.

14.

Tyrosine phosphorylation of CD13 regulates inflammatory cell-cell adhesion and monocyte trafficking.

Subramani J, Ghosh M, Rahman MM, Caromile LA, Gerber C, Rezaul K, Han DK, Shapiro LH.

J Immunol. 2013 Oct 1;191(7):3905-12. doi: 10.4049/jimmunol.1301348. Epub 2013 Aug 30.

15.

Prostate specific membrane antigen produces pro-angiogenic laminin peptides downstream of matrix metalloprotease-2.

Conway RE, Joiner K, Patterson A, Bourgeois D, Rampp R, Hannah BC, McReynolds S, Elder JM, Gilfilen H, Shapiro LH.

Angiogenesis. 2013 Oct;16(4):847-60. doi: 10.1007/s10456-013-9360-y. Epub 2013 Jun 18.

PMID:
23775497
16.

CD13 is essential for inflammatory trafficking and infarct healing following permanent coronary artery occlusion in mice.

Pereira FE, Cronin C, Ghosh M, Zhou SY, Agosto M, Subramani J, Wang R, Shen JB, Schacke W, Liang B, Yang TH, McAulliffe B, Liang BT, Shapiro LH.

Cardiovasc Res. 2013 Oct 1;100(1):74-83. doi: 10.1093/cvr/cvt155. Epub 2013 Jun 12.

17.
18.

Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization.

Grant CL, Caromile LA, Ho V, Durrani K, Rahman MM, Claffey KP, Fong GH, Shapiro LH.

PLoS One. 2012;7(7):e41285. doi: 10.1371/journal.pone.0041285. Epub 2012 Jul 18. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/a66c73f8-4cef-454c-9595-11f657ade2bc. Ho, Vivienne [added].

19.

CD13 regulates dendritic cell cross-presentation and T cell responses by inhibiting receptor-mediated antigen uptake.

Ghosh M, McAuliffe B, Subramani J, Basu S, Shapiro LH.

J Immunol. 2012 Jun 1;188(11):5489-99. doi: 10.4049/jimmunol.1103490. Epub 2012 Apr 27.

20.

CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse.

Winnicka B, O'Conor C, Schacke W, Vernier K, Grant CL, Fenteany FH, Pereira FE, Liang B, Kaur A, Zhao R, Montrose DC, Rosenberg DW, Aguila HL, Shapiro LH.

J Leukoc Biol. 2010 Aug;88(2):347-59. doi: 10.1189/jlb.0210065. Epub 2010 Apr 29.

21.

Anti-CD13 Abs in children with extensive chronic GVHD and their relation to soluble CD13 after allogeneic blood and marrow transplantation from a Children's Oncology Groups Study, ASCT0031.

Cuvelier GD, Kariminia A, Fujii H, Aslanian S, Wall D, Goldman F, Grupp SA, Dunn SE, Krailo M, Shapiro LH, Gilman A, Schultz KR.

Bone Marrow Transplant. 2010 Nov;45(11):1653-7. doi: 10.1038/bmt.2010.15. Epub 2010 Mar 1.

22.

CD13 is a novel mediator of monocytic/endothelial cell adhesion.

Mina-Osorio P, Winnicka B, O'Conor C, Grant CL, Vogel LK, Rodriguez-Pinto D, Holmes KV, Ortega E, Shapiro LH.

J Leukoc Biol. 2008 Aug;84(2):448-59. doi: 10.1189/jlb.1107802. Epub 2008 May 21.

23.

CD13/APN transcription is regulated by the proto-oncogene c-Maf via an atypical response element.

Mahoney KM, Petrovic N, Schacke W, Shapiro LH.

Gene. 2007 Nov 15;403(1-2):178-87. Epub 2007 Aug 25.

24.

CD13/APN regulates endothelial invasion and filopodia formation.

Petrovic N, Schacke W, Gahagan JR, O'Conor CA, Winnicka B, Conway RE, Mina-Osorio P, Shapiro LH.

Blood. 2007 Jul 1;110(1):142-50. Epub 2007 Mar 15.

25.

Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.

Conway RE, Petrovic N, Li Z, Heston W, Wu D, Shapiro LH.

Mol Cell Biol. 2006 Jul;26(14):5310-24.

26.

Molecular phylogeny of Banza (Orthoptera: Tettigoniidae), the endemic katydids of the Hawaiian Archipelago.

Shapiro LH, Strazanac JS, Roderick GK.

Mol Phylogenet Evol. 2006 Oct;41(1):53-63. Epub 2006 Apr 25.

PMID:
16781170
27.

CD13/Aminopeptidase N overexpression by basic fibroblast growth factor mediates enhanced invasiveness of 1F6 human melanoma cells.

Fontijn D, Duyndam MC, van Berkel MP, Yuana Y, Shapiro LH, Pinedo HM, Broxterman HJ, Boven E.

Br J Cancer. 2006 Jun 5;94(11):1627-36.

28.

CD13 in cell adhesion: aminopeptidase N (CD13) mediates homotypic aggregation of monocytic cells.

Mina-Osorio P, Shapiro LH, Ortega E.

J Leukoc Biol. 2006 Apr;79(4):719-30. Epub 2006 Jan 13.

PMID:
16415167
29.

Cells of human aminopeptidase N (CD13) transgenic mice are infected by human coronavirus-229E in vitro, but not in vivo.

Wentworth DE, Tresnan DB, Turner BC, Lerman IR, Bullis B, Hemmila EM, Levis R, Shapiro LH, Holmes KV.

Virology. 2005 May 10;335(2):185-97.

30.

CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells.

Petrovic N, Bhagwat SV, Ratzan WJ, Ostrowski MC, Shapiro LH.

J Biol Chem. 2003 Dec 5;278(49):49358-68. Epub 2003 Sep 24.

31.

The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis.

Bhagwat SV, Petrovic N, Okamoto Y, Shapiro LH.

Blood. 2003 Mar 1;101(5):1818-26. Epub 2002 Oct 24.

32.

Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

Sampath J, Sun D, Kidd VJ, Grenet J, Gandhi A, Shapiro LH, Wang Q, Zambetti GP, Schuetz JD.

J Biol Chem. 2001 Oct 19;276(42):39359-67. Epub 2001 Aug 1.

33.

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation.

Bhagwat SV, Lahdenranta J, Giordano R, Arap W, Pasqualini R, Shapiro LH.

Blood. 2001 Feb 1;97(3):652-9.

34.

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

Pasqualini R, Koivunen E, Kain R, Lahdenranta J, Sakamoto M, Stryhn A, Ashmun RA, Shapiro LH, Arap W, Ruoslahti E.

Cancer Res. 2000 Feb 1;60(3):722-7.

35.

c-Maf induces monocytic differentiation and apoptosis in bipotent myeloid progenitors.

Hegde SP, Zhao J, Ashmun RA, Shapiro LH.

Blood. 1999 Sep 1;94(5):1578-89.

36.

Role of secondary structure in discrimination between constitutive and inducible activators.

Parker D, Rivera M, Zor T, Henrion-Caude A, Radhakrishnan I, Kumar A, Shapiro LH, Wright PE, Montminy M, Brindle PK.

Mol Cell Biol. 1999 Aug;19(8):5601-7.

37.
38.

bca: an activation-related B-cell gene.

Gangi-Peterson L, Peterson SN, Shapiro LH, Golding A, Caricchio R, Cohen DI, Margulies DH, Cohen PL.

Mol Immunol. 1998 Jan;35(1):55-63.

PMID:
9683264
39.

HYBRIDIZATION AND GEOGRAPHIC VARIATION IN TWO MEADOW KATYDID CONTACT ZONES.

Shapiro LH.

Evolution. 1998 Jun;52(3):784-796. doi: 10.1111/j.1558-5646.1998.tb03702.x.

PMID:
28565255
40.

c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation.

Hedge SP, Kumar A, Kurschner C, Shapiro LH.

Mol Cell Biol. 1998 May;18(5):2729-37.

41.

A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions.

Yang C, Shapiro LH, Rivera M, Kumar A, Brindle PK.

Mol Cell Biol. 1998 Apr;18(4):2218-29.

42.

Redundant functions of B-Myb and c-Myb in differentiating myeloid cells.

Golay J, Broccoli V, Borleri GM, Erba E, Faretta M, Basilico L, Ying GG, Piccinini G, Shapiro LH, Lovrić J, Nawrath M, Mölling K, Rambaldi A, Introna M.

Cell Growth Differ. 1997 Dec;8(12):1305-16.

43.

Human aminopeptidase N is encoded by 20 exons.

Lerche C, Vogel LK, Shapiro LH, Norén O, Sjöström H.

Mamm Genome. 1996 Sep;7(9):712-3. No abstract available.

PMID:
8703138
44.

Stromal cell-mediated transcriptional regulation of the CD13/aminopeptidase N gene in leukemic cells.

Saito M, Kumagai M, Okazaki T, Nakazawa S, Shapiro LH, Look AT, Campana D.

Leukemia. 1995 Sep;9(9):1508-16.

PMID:
7658720
45.
46.

Myb and Ets proteins cooperate to transactivate an early myeloid gene.

Shapiro LH.

J Biol Chem. 1995 Apr 14;270(15):8763-71.

47.

Transcriptional regulation in myeloid cell differentiation.

Shapiro LH, Look AT.

Curr Opin Hematol. 1995 Jan;2(1):3-11. Review.

PMID:
9371966
48.

B-cell-specific demethylation of BTK, the defective gene in X-linked agammaglobulinemia.

Parolini O, Rohrer J, Shapiro LH, Conley ME.

Immunogenetics. 1995;42(2):129-35.

PMID:
7541776
49.
50.

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