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Errors in Methodology Affect Diagnostic Accuracy of High-Speed Videomicroscopy Analysis in Primary Ciliary Dyskinesia.

Shapiro AJ, Leigh MW, Omran H, Lavergne V, Knowles MR.

Chest. 2019 Nov;156(5):1032-1033. doi: 10.1016/j.chest.2019.06.021. No abstract available.


High-Speed Videomicrosopy Analysis Presents Limitations in Diagnosis of Primary Ciliary Dyskinesia.

Shapiro AJ, Ferkol TW, Manion M, Leigh MW, Davis SD, Knowles MR.

Am J Respir Crit Care Med. 2019 Aug 21. doi: 10.1164/rccm.201907-1366LE. [Epub ahead of print] No abstract available.


Python BMDS: A Python interface library and web application for the canonical EPA dose-response modeling software.

Pham LL, Watford S, Friedman KP, Wignall J, Shapiro AJ.

Reprod Toxicol. 2019 Aug 12;90:102-108. doi: 10.1016/j.reprotox.2019.07.013. [Epub ahead of print]


A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives.

Pelch K, Wignall JA, Goldstone AE, Ross PK, Blain RB, Shapiro AJ, Holmgren SD, Hsieh JH, Svoboda D, Auerbach SS, Parham FM, Masten SA, Walker V, Rooney A, Thayer KA.

Toxicology. 2019 Aug 1;424:152235. doi: 10.1016/j.tox.2019.06.006. Epub 2019 Jun 12. Review.


Comparison of 2-Hour Oral Glucose Tolerance Test and Hemoglobin A1C in the Identification of Pre-Diabetes in Women with Infertility and Recurrent Pregnancy Loss.

Shapiro AJ, Holden EC, McGovern PG, Alderson D, Morelli SS.

Clin Med Insights Reprod Health. 2019 Mar 22;13:1179558119831280. doi: 10.1177/1179558119831280. eCollection 2019.


Nasal Nitric Oxide in Primary Immunodeficiency and Primary Ciliary Dyskinesia: Helping to Distinguish Between Clinically Similar Diseases.

Zysman-Colman ZN, Kaspy KR, Alizadehfar R, NyKamp KR, Zariwala MA, Knowles MR, Vinh DC, Shapiro AJ.

J Clin Immunol. 2019 Feb;39(2):216-224. doi: 10.1007/s10875-019-00613-8. Epub 2019 Mar 26.


Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here.

Behl M, Ryan K, Hsieh JH, Parham F, Shapiro AJ, Collins BJ, Sipes NS, Birnbaum LS, Bucher JR, Foster PMD, Walker NJ, Paules RS, Tice RR.

Toxicol Sci. 2019 Jan 1;167(1):6-14. doi: 10.1093/toxsci/kfy278. Erratum in: Toxicol Sci. 2019 Apr 1;168(2):644.


Summary for Clinicians: Diagnosis of Primary Ciliary Dyskinesia.

O'Connor MG, Griffiths A, Iyer NP, Shapiro AJ, Wilson KC, Thomson CC.

Ann Am Thorac Soc. 2019 Feb;16(2):171-174. doi: 10.1513/AnnalsATS.201810-693CME. No abstract available.


Software Tools to Facilitate Systematic Review Used for Cancer Hazard Identification.

Shapiro AJ, Antoni S, Guyton KZ, Lunn RM, Loomis D, Rusyn I, Jahnke GD, Schwingl PJ, Mehta SS, Addington J, Guha N.

Environ Health Perspect. 2018 Oct;126(10):104501. doi: 10.1289/EHP4224.


Application of Benchmark Concentration (BMC) Analysis on Zebrafish Data: A New Perspective for Quantifying Toxicity in Alternative Animal Models.

Hsieh JH, Ryan K, Sedykh A, Lin JA, Shapiro AJ, Parham F, Behl M.

Toxicol Sci. 2019 Jan 1;167(1):92-104. doi: 10.1093/toxsci/kfy258.


The prevalence of the defining features of primary ciliary dyskinesia within a cri du chat syndrome cohort.

Sanders CD, Leigh MW, Chao KC, Weck KE, King I, Wolf WE, Campbell DJ, Knowles MR, Zariwala MA, Shapiro AJ.

Pediatr Pulmonol. 2018 Nov;53(11):1565-1573. doi: 10.1002/ppul.24159. Epub 2018 Sep 20.


Vitamin D levels are not associated with ovarian reserve in a group of infertile women with a high prevalance of diminished ovarian reserve.

Shapiro AJ, Darmon SK, Barad DH, Gleicher N, Kushnir VA.

Fertil Steril. 2018 Sep;110(4):761-766.e1. doi: 10.1016/j.fertnstert.2018.05.005.


Primary Ciliary Dyskinesia: Longitudinal Study of Lung Disease by Ultrastructure Defect and Genotype.

Davis SD, Rosenfeld M, Lee HS, Ferkol TW, Sagel SD, Dell SD, Milla C, Pittman JE, Shapiro AJ, Sullivan KM, Nykamp KR, Krischer JP, Zariwala MA, Knowles MR, Leigh MW.

Am J Respir Crit Care Med. 2019 Jan 15;199(2):190-198. doi: 10.1164/rccm.201803-0548OC.


Beyond the RfD: Broad Application of a Probabilistic Approach to Improve Chemical Dose-Response Assessments for Noncancer Effects.

Chiu WA, Axelrad DA, Dalaijamts C, Dockins C, Shao K, Shapiro AJ, Paoli G.

Environ Health Perspect. 2018 Jun 28;126(6):067009. doi: 10.1289/EHP3368. eCollection 2018 Jun.


Diagnosis of Primary Ciliary Dyskinesia. An Official American Thoracic Society Clinical Practice Guideline.

Shapiro AJ, Davis SD, Polineni D, Manion M, Rosenfeld M, Dell SD, Chilvers MA, Ferkol TW, Zariwala MA, Sagel SD, Josephson M, Morgan L, Yilmaz O, Olivier KN, Milla C, Pittman JE, Daniels MLA, Jones MH, Janahi IA, Ware SM, Daniel SJ, Cooper ML, Nogee LM, Anton B, Eastvold T, Ehrne L, Guadagno E, Knowles MR, Leigh MW, Lavergne V; American Thoracic Society Assembly on Pediatrics.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):e24-e39. doi: 10.1164/rccm.201805-0819ST.


Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.

Costiniuk CT, Mehraj V, Routy JP, de Castro C, Wasef N, Jenabian MA, Salahuddin S, Lebouché B, Cox J, Szabo J, Klein M, Lands L, Shapiro AJ.

AIDS Res Treat. 2018 Jan 9;2018:7645125. doi: 10.1155/2018/7645125. eCollection 2018.


Human and animal evidence of potential transgenerational inheritance of health effects: An evidence map and state-of-the-science evaluation.

Walker VR, Boyles AL, Pelch KE, Holmgren SD, Shapiro AJ, Blystone CR, Devito MJ, Newbold RR, Blain R, Hartman P, Thayer KA, Rooney AA.

Environ Int. 2018 Jun;115:48-69. doi: 10.1016/j.envint.2017.12.032. Epub 2018 Mar 14. Review.


A Web-Based System for Bayesian Benchmark Dose Estimation.

Shao K, Shapiro AJ.

Environ Health Perspect. 2018 Jan 11;126(1):017002. doi: 10.1289/EHP1289.


Value of transmission electron microscopy for primary ciliary dyskinesia diagnosis in the era of molecular medicine: Genetic defects with normal and non-diagnostic ciliary ultrastructure.

Shapiro AJ, Leigh MW.

Ultrastruct Pathol. 2017 Nov-Dec;41(6):373-385. doi: 10.1080/01913123.2017.1362088. Epub 2017 Sep 15. Review.


A comparison of nasal nitric oxide measurement modes.

Deschamp AR, Schornick L, Clem C, Hazucha M, Shapiro AJ, Davis SD.

Pediatr Pulmonol. 2017 Nov;52(11):1381-1382. doi: 10.1002/ppul.23780. Epub 2017 Aug 16. No abstract available.


Vector-borne and zoonotic diseases of dogs in North-west New South Wales and the Northern Territory, Australia.

Shapiro AJ, Brown G, Norris JM, Bosward KL, Marriot DJ, Balakrishnan N, Breitschwerdt EB, Malik R.

BMC Vet Res. 2017 Aug 15;13(1):238. doi: 10.1186/s12917-017-1169-2.


An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library.

Sipes NS, Wambaugh JF, Pearce R, Auerbach SS, Wetmore BA, Hsieh JH, Shapiro AJ, Svoboda D, DeVito MJ, Ferguson SS.

Environ Sci Technol. 2017 Sep 19;51(18):10786-10796. doi: 10.1021/acs.est.7b00650. Epub 2017 Sep 6.


An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases.

Kristof AS, Petrof BJ, Hamid Q, Kolb M, Landry JS, MacKenzie A, McCormack FX, Murawski IJ, Moss J, Rauch F, Rosas IO, Shapiro AJ, Smith BM, Thomas DY, Trapnell BC, Young LR, Zariwala MA; ATS Assembly on Respiratory Cell and Molecular Biology.

Ann Am Thorac Soc. 2017 Aug;14(8):1239-1247. doi: 10.1513/AnnalsATS.201705-406WS.


Effect of race and ethnicity on utilization and outcomes of assisted reproductive technology in the USA.

Shapiro AJ, Darmon SK, Barad DH, Albertini DF, Gleicher N, Kushnir VA.

Reprod Biol Endocrinol. 2017 Jun 8;15(1):44. doi: 10.1186/s12958-017-0262-5.


Accuracy of Nasal Nitric Oxide Measurement as a Diagnostic Test for Primary Ciliary Dyskinesia. A Systematic Review and Meta-analysis.

Shapiro AJ, Josephson M, Rosenfeld M, Yilmaz O, Davis SD, Polineni D, Guadagno E, Leigh MW, Lavergne V.

Ann Am Thorac Soc. 2017 Jul;14(7):1184-1196. doi: 10.1513/AnnalsATS.201701-062SR. Review.


ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data.

Lavender CA, Shapiro AJ, Burkholder AB, Bennett BD, Adelman K, Fargo DC.

Nucleic Acids Res. 2017 Jun 2;45(10):5678-5690. doi: 10.1093/nar/gkx270.


Detention of Immigrant Children.


Pediatrics. 2017 May;139(5). pii: e20170483. doi: 10.1542/peds.2017-0483. Epub 2017 Mar 13.


Point of care lung ultrasound of children with acute asthma exacerbations in the pediatric ED.

Dankoff S, Li P, Shapiro AJ, Varshney T, Dubrovsky AS.

Am J Emerg Med. 2017 Apr;35(4):615-622. doi: 10.1016/j.ajem.2016.12.057. Epub 2016 Dec 26.


Utilization of third-party in vitro fertilization in the United States.

Kushnir VA, Darmon SK, Shapiro AJ, Albertini DF, Barad DH, Gleicher N.

Am J Obstet Gynecol. 2017 Mar;216(3):266.e1-266.e10. doi: 10.1016/j.ajog.2016.11.1022. Epub 2016 Nov 14.


Q Fever (Coxiella burnetii) Knowledge and Attitudes of Australian Cat Breeders and Their Husbandry Practices.

Shapiro AJ, Norris JM, Bosward KL, Heller J.

Zoonoses Public Health. 2017 Jun;64(4):252-261. doi: 10.1111/zph.12305. Epub 2016 Sep 13.


Point-of-care lung ultrasound in young children with respiratory tract infections and wheeze.

Varshney T, Mok E, Shapiro AJ, Li P, Dubrovsky AS.

Emerg Med J. 2016 Sep;33(9):603-10. doi: 10.1136/emermed-2015-205302. Epub 2016 Apr 22.


Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents.

Leigh MW, Ferkol TW, Davis SD, Lee HS, Rosenfeld M, Dell SD, Sagel SD, Milla C, Olivier KN, Sullivan KM, Zariwala MA, Pittman JE, Shapiro AJ, Carson JL, Krischer J, Hazucha MJ, Knowles MR.

Ann Am Thorac Soc. 2016 Aug;13(8):1305-13. doi: 10.1513/AnnalsATS.201511-748OC.


Primary Ciliary Dyskinesia.

Fitzgerald DA, Shapiro AJ.

Paediatr Respir Rev. 2016 Mar;18:1-2. doi: 10.1016/j.prrv.2015.11.010. Epub 2015 Dec 29. No abstract available.


When to suspect primary ciliary dyskinesia in children.

Fitzgerald DA, Shapiro AJ.

Paediatr Respir Rev. 2016 Mar;18:3-7. doi: 10.1016/j.prrv.2015.11.006. Epub 2015 Nov 23. Review.


Seroprevalence of Coxiella burnetii in Australian dogs.

Shapiro AJ, Norris JM, Heller J, Brown G, Malik R, Bosward KL.

Zoonoses Public Health. 2016 Sep;63(6):458-66. doi: 10.1111/zph.12250. Epub 2016 Jan 5.


Congenital Heart Disease and Primary Ciliary Dyskinesia.

Harrison MJ, Shapiro AJ, Kennedy MP.

Paediatr Respir Rev. 2016 Mar;18:25-32. doi: 10.1016/j.prrv.2015.09.003. Epub 2015 Sep 26. Review.


Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review.

Shapiro AJ, Zariwala MA, Ferkol T, Davis SD, Sagel SD, Dell SD, Rosenfeld M, Olivier KN, Milla C, Daniel SJ, Kimple AJ, Manion M, Knowles MR, Leigh MW; Genetic Disorders of Mucociliary Clearance Consortium.

Pediatr Pulmonol. 2016 Feb;51(2):115-32. doi: 10.1002/ppul.23304. Epub 2015 Sep 29. Review.


Bioengineered stem cells as an alternative for islet cell transplantation.

Moore SJ, Gala-Lopez BL, Pepper AR, Pawlick RL, Shapiro AJ.

World J Transplant. 2015 Mar 24;5(1):1-10. doi: 10.5500/wjt.v5.i1.1. Review.


Seroprevalence of Coxiella burnetii in domesticated and feral cats in eastern Australia.

Shapiro AJ, Bosward KL, Heller J, Norris JM.

Vet Microbiol. 2015 May 15;177(1-2):154-61. doi: 10.1016/j.vetmic.2015.02.011. Epub 2015 Feb 23.


Clinical features of childhood primary ciliary dyskinesia by genotype and ultrastructural phenotype.

Davis SD, Ferkol TW, Rosenfeld M, Lee HS, Dell SD, Sagel SD, Milla C, Zariwala MA, Pittman JE, Shapiro AJ, Carson JL, Krischer JP, Hazucha MJ, Cooper ML, Knowles MR, Leigh MW.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):316-24. doi: 10.1164/rccm.201409-1672OC.



Shapiro AJ, Leigh MW.

Chest. 2014 Nov;146(5):e167-8. doi: 10.1378/chest.14-1282. No abstract available.


Cri du chat syndrome and primary ciliary dyskinesia: a common genetic cause on chromosome 5p.

Shapiro AJ, Weck KE, Chao KC, Rosenfeld M, Nygren AO, Knowles MR, Leigh MW, Zariwala MA.

J Pediatr. 2014 Oct;165(4):858-61. doi: 10.1016/j.jpeds.2014.06.048. Epub 2014 Jul 25.


Filamin A mutation may be associated with diffuse lung disease mimicking bronchopulmonary dysplasia in premature newborns.

Lord A, Shapiro AJ, Saint-Martin C, Claveau M, Melançon S, Wintermark P.

Respir Care. 2014 Nov;59(11):e171-7. doi: 10.4187/respcare.02847. Epub 2014 Jul 22.


Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challenges.

Bruni A, Gala-Lopez B, Pepper AR, Abualhassan NS, Shapiro AJ.

Diabetes Metab Syndr Obes. 2014 Jun 23;7:211-23. doi: 10.2147/DMSO.S50789. eCollection 2014. Review.


Impact of adverse pancreatic injury at surgical procurement upon islet isolation outcome.

Andres A, Kin T, O'Gorman D, Bigam D, Kneteman N, Senior P, Shapiro AJ.

Transpl Int. 2014 Nov;27(11):1135-42. doi: 10.1111/tri.12392. Epub 2014 Aug 24.


The prevalence of clinical features associated with primary ciliary dyskinesia in a heterotaxy population: results of a web-based survey.

Shapiro AJ, Tolleson-Rinehart S, Zariwala MA, Knowles MR, Leigh MW.

Cardiol Young. 2015 Apr;25(4):752-9. doi: 10.1017/S1047951114000912. Epub 2014 Jun 6.


Laterality defects other than situs inversus totalis in primary ciliary dyskinesia: insights into situs ambiguus and heterotaxy.

Shapiro AJ, Davis SD, Ferkol T, Dell SD, Rosenfeld M, Olivier KN, Sagel SD, Milla C, Zariwala MA, Wolf W, Carson JL, Hazucha MJ, Burns K, Robinson B, Knowles MR, Leigh MW; Genetic Disorders of Mucociliary Clearance Consortium.

Chest. 2014 Nov;146(5):1176-1186. doi: 10.1378/chest.13-1704.


Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.

Wignall JA, Shapiro AJ, Wright FA, Woodruff TJ, Chiu WA, Guyton KZ, Rusyn I.

Environ Health Perspect. 2014 May;122(5):499-505. doi: 10.1289/ehp.1307539. Epub 2014 Feb 25.


Current status of clinical islet transplantation.

Pepper AR, Gala-Lopez B, Ziff O, Shapiro AJ.

World J Transplant. 2013 Dec 24;3(4):48-53. doi: 10.5500/wjt.v3.i4.48.


Standardizing nasal nitric oxide measurement as a test for primary ciliary dyskinesia.

Leigh MW, Hazucha MJ, Chawla KK, Baker BR, Shapiro AJ, Brown DE, Lavange LM, Horton BJ, Qaqish B, Carson JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Rosenfeld M, Milla C, Lee HS, Krischer J, Zariwala MA, Knowles MR.

Ann Am Thorac Soc. 2013 Dec;10(6):574-81. doi: 10.1513/AnnalsATS.201305-110OC.

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