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Items: 32

1.

Plasma and wound fluid levels of eight proangiogenic proteins are elevated after colorectal resection.

Shantha Kumara H, Yan XH, Pettke E, Cekic V, Gandhi ND, Bellini GA, Whelan RL.

World J Gastrointest Oncol. 2019 Jun 15;11(6):470-488. doi: 10.4251/wjgo.v11.i6.470.

2.

Sclerotherapy needle injections can expand the subserosal and muscularis propria layers and cause a stable mucosal lift in ESD/EMR patients.

Sandhu J, Winkler C, Yan X, Sharabi A, Grimes Z, Shantha Kumara HMC, Cekic V, Whelan R.

Surg Endosc. 2019 Mar;33(3):949-958. doi: 10.1007/s00464-018-6521-5. Epub 2018 Oct 22.

3.

Plasma levels of the proangiogenic protein CXCL16 remains elevated for 1 month after minimally invasive colorectal cancer resection.

Shantha Kumara HMC, Pettke E, Shah A, Yan X, Cekic V, Downing MA, Gandhi ND, Whelan RL.

World J Surg Oncol. 2018 Jul 7;16(1):132. doi: 10.1186/s12957-018-1418-2.

4.

Plasma interleukin-8 levels are persistently elevated for 1 month after minimally invasive colorectal resection for colorectal cancer.

Shantha Kumara HMC, Sutton E, Bellini GA, Yan X, Cekic V, Gandhi ND, Whelan RL.

Mol Clin Oncol. 2018 Mar;8(3):471-476. doi: 10.3892/mco.2017.1538. Epub 2017 Dec 18.

5.

Risk factors for superficial surgical site infection after elective rectal cancer resection: a multivariate analysis of 8880 patients from the American College of Surgeons National Surgical Quality Improvement Program database.

Sutton E, Miyagaki H, Bellini G, Shantha Kumara HM, Yan X, Howe B, Feigel A, Whelan RL.

J Surg Res. 2017 Jan;207:205-214. doi: 10.1016/j.jss.2016.08.082. Epub 2016 Aug 31.

PMID:
27979478
6.

Plasma chitinase 3-like 1 is persistently elevated during first month after minimally invasive colorectal cancer resection.

Shantha Kumara HM, Gaita D, Miyagaki H, Yan X, Hearth SA, Njoh L, Cekic V, Whelan RL.

World J Gastrointest Oncol. 2016 Aug 15;8(8):607-14. doi: 10.4251/wjgo.v8.i8.607.

7.

Human Blood Autoantibodies in the Detection of Colorectal Cancer.

Negm OH, Hamed MR, Schoen RE, Whelan RL, Steele RJ, Scholefield J, Dilnot EM, Shantha Kumara HM, Robertson JF, Sewell HF.

PLoS One. 2016 Jul 6;11(7):e0156971. doi: 10.1371/journal.pone.0156971. eCollection 2016.

8.

Surgical Treatment of Diverticulitis: Hand-Assisted Laparoscopic Resection Is Predominantly Used for Complex Cases and Is Associated With Increased Postoperative Complications and Prolonged Hospitalization.

Miyagaki H, Rhee R, Shantha Kumara HM, Yan X, Njoh L, Cekic V, Whelan RL.

Surg Innov. 2016 Jun;23(3):277-83. doi: 10.1177/1553350615618285. Epub 2015 Nov 26.

PMID:
26611789
9.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

10.

Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.

Shantha Kumara H, Kirchoff D, Caballero OL, Su T, Ahmed A, Herath SA, Njoh L, Cekic V, Simpson AJ, Cordon-Cardo C, Whelan RL.

Oncoscience. 2015 Jul 1;2(6):607-14. eCollection 2015.

11.

A multi-targeted approach to suppress tumor-promoting inflammation.

Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, Guha G, Vasantha Rupasinghe HP, Fujii H, Honoki K, Mehta K, Aquilano K, Lowe L, Hofseth LJ, Ricciardiello L, Ciriolo MR, Singh N, Whelan RL, Chaturvedi R, Ashraf SS, Shantha Kumara HMC, Nowsheen S, Mohammed SI, Keith WN, Helferich WG, Yang X.

Semin Cancer Biol. 2015 Dec;35 Suppl:S151-S184. doi: 10.1016/j.semcancer.2015.03.006. Epub 2015 May 5. Review.

12.

Plasma monocyte chemotactic protein-1 remains elevated after minimally invasive colorectal cancer resection.

Shantha Kumara HM, Myers EA, Herath SA, Jang JH, Njoh L, Yan X, Kirchoff D, Cekic V, Luchtefeld M, Whelan RL.

World J Gastrointest Oncol. 2014 Oct 15;6(10):413-9. doi: 10.4251/wjgo.v6.i10.413.

13.

Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases.

Shantha Kumara HM, Gaita DJ, Miyagaki H, Yan X, Herath SA, Cekic V, Whelan RL.

Surg Endosc. 2014 Dec;28(12):3322-8. doi: 10.1007/s00464-014-3612-9. Epub 2014 Jun 18.

PMID:
24939159
14.

Minimally invasive colorectal resection for benign pathology is associated with persistent proangiogenic plasma compositional changes.

Shantha Kumara HM, Myers EA, Herath SA, Njoh L, Yan X, Kirchoff D, Dujovny N, Whelan RL.

Dis Colon Rectum. 2014 Jun;57(6):740-6. doi: 10.1097/DCR.0000000000000062.

PMID:
24807599
15.

MAGE-A3 is highly expressed in a subset of colorectal cancer patients.

Shantha Kumara HM, Grieco MJ, Caballero OL, Su T, Ahmed A, Ritter E, Gnjatic S, Cekic V, Old LJ, Simpson AJ, Cordon-Cardo C, Whelan RL.

Cancer Immun. 2012;12:16. Epub 2012 Dec 28.

16.
17.

Perioperative polyphenon E- and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models.

Yan X, Gardner TR, Grieco M, Herath SA, Jang JH, Kirchoff D, Njoh L, Shantha Kumara HM, Naffouje S, Whelan RL.

Surg Endosc. 2012 Jul;26(7):1856-64. doi: 10.1007/s00464-011-2114-2. Epub 2012 Jan 19.

PMID:
22258296
18.

Plasma soluble vascular adhesion molecule-1 levels are persistently elevated during the first month after colorectal cancer resection.

Shantha Kumara HM, Tohme ST, Herath SA, Yan X, Senagore AJ, Nasar A, Kalady MF, Baxter R, Whelan RL.

Surg Endosc. 2012 Jun;26(6):1759-64. doi: 10.1007/s00464-011-2112-4. Epub 2012 Jan 5.

PMID:
22219007
19.

Plasma from the second and third weeks after open colorectal resection for cancer stimulates in vitro endothelial cell growth, migration, and invasion.

Shantha Kumara HM, Kirchoff D, Naffouje S, Grieco M, Herath SA, Dujovny N, Kalady MF, Hyman N, Njoh L, Whelan RL.

Surg Endosc. 2012 Mar;26(3):790-5. doi: 10.1007/s00464-011-1953-1. Epub 2011 Nov 15.

PMID:
22083320
20.

Minimally invasive colorectal resection is associated with a transient increase in plasma hepatocyte growth factor levels early after surgery for colon cancer.

Shantha Kumara HM, Tohme ST, Kim IY, Kim DG, Kalady MF, Luchtefeld M, Hoffman K, Dimaggio V, Whelan RL.

Surg Innov. 2011 Sep;18(3):254-8. doi: 10.1177/1553350611399588. Epub 2011 Mar 11.

PMID:
21398340
21.

CpG ODN, Toll like receptor (TLR)-9 agonist, inhibits metastatic colon adenocarcinoma in a murine hepatic tumor model.

Kim IY, Yan X, Tohme S, Ahmed A, Cordon-Cardo C, Shantha Kumara HM, Kim SK, Whelan RL.

J Surg Res. 2012 May 15;174(2):284-90. doi: 10.1016/j.jss.2010.12.021. Epub 2011 Jan 15.

PMID:
21324492
22.

Minimally invasive colon resection is associated with a persistent increase in plasma PlGF levels following cancer resection.

Shantha Kumara HM, Cabot JC, Yan X, Herath SA, Luchtefeld M, Kalady MF, Feingold DL, Baxter R, Whelan RL.

Surg Endosc. 2011 Jul;25(7):2153-8. doi: 10.1007/s00464-010-1514-z. Epub 2010 Dec 24.

PMID:
21184108
23.

Plasma levels of angiostatin and endostatin remain unchanged for the first 3 weeks after colorectal cancer surgery.

Shantha Kumara HM, Tohme ST, Yan X, Nasar A, Senagore AJ, Kalady MF, Hyman N, Kim IY, Whelan RL.

Surg Endosc. 2011 Jun;25(6):1939-44. doi: 10.1007/s00464-010-1491-2. Epub 2010 Dec 22.

PMID:
21181203
24.

Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2).

Shantha Kumara HM, Grieco MJ, Yan X, Kalady MF, DiMaggio V, Kim DG, Hyman N, Feingold DL, Whelan RL.

Surg Endosc. 2010 Oct;24(10):2581-7. doi: 10.1007/s00464-010-1008-z. Epub 2010 Mar 31.

PMID:
20354881
25.

Minimally invasive colorectal resection is associated with a rapid and sustained decrease in plasma levels of epidermal growth factor (EGF) in the colon cancer setting.

Grieco MJ, Shantha Kumara HM, Baxter R, Dujovny N, Kalady MF, Cekic V, Luchtefeld M, Whelan RL.

Surg Endosc. 2010 Oct;24(10):2617-22. doi: 10.1007/s00464-010-1018-x. Epub 2010 Mar 31.

PMID:
20354877
26.

Platelet-derived growth factor (subtype BB) is elevated in patients with colorectal carcinoma.

Belizon A, Balik E, Horst PK, Shantha Kumara HM, Nasar A, Whelan RL.

Dis Colon Rectum. 2009 Jun;52(6):1166-71. doi: 10.1007/DCR.0b013e3181a0b388.

PMID:
19581863
27.

Minimally invasive colon resection for malignant colonic conditions is associated with a transient early increase in plasma sVEGFR1 and a decrease in sVEGFR2 levels after surgery.

Shantha Kumara HM, Cabot JC, Hoffman A, Luchtefeld M, Kalady MF, Hyman N, Feingold D, Baxter R, Whelan RL.

Surg Endosc. 2010 Feb;24(2):283-9. doi: 10.1007/s00464-009-0575-3. Epub 2009 Jun 24.

PMID:
19551437
28.

Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion.

Kumara HM, Feingold D, Kalady M, Dujovny N, Senagore A, Hyman N, Cekic V, Whelan RL.

Ann Surg. 2009 Jun;249(6):973-7. doi: 10.1097/SLA.0b013e3181a6cd72. Erratum in: Ann Surg. 2009 Dec;250(6):1046. Shantha Kumara, H M C [corrected to Kumara, H M C Shantha].

PMID:
19474682
29.

Minimally invasive colon resection is associated with a transient increase in plasma sVEGFR1 levels and a decrease in sVEGFR2 levels during the early postoperative period.

Shantha Kumara HM, Cabot JC, Hoffman A, Luchtefeld M, Kalady MF, Hyman N, Feingold D, Baxter R, Whelan RL.

Surg Endosc. 2009 Apr;23(4):694-9. doi: 10.1007/s00464-008-0323-0. Epub 2009 Jan 28.

PMID:
19184203
30.

Colorectal resection, both open and laparoscopic-assisted, in patients with benign indications is associated with proangiogenic changes in plasma angiopoietin 1 and 2 levels.

Shantha Kumara HM, Hoffman A, Kim IY, Feingold D, Dujovny N, Kalady M, Luchtefeld M, Whelan RL.

Surg Endosc. 2009 Feb;23(2):409-15. doi: 10.1007/s00464-008-0132-5. Epub 2008 Sep 24. Erratum in: Surg Endosc. 2009 Feb;23(2):416. Kallady, M [corrected to Kalady, M].

PMID:
18813991
31.

Perioperative GMCSF limits the proangiogenic plasma protein changes associated with colorectal cancer resection.

Shantha Kumara HM, Kirman I, Feingold D, Cekic V, Nasar A, Arnell T, Balik E, Hoffman A, Baxter R, Conte S, Whelan RL.

Eur J Surg Oncol. 2009 Mar;35(3):295-301. doi: 10.1016/j.ejso.2008.07.012. Epub 2008 Sep 7.

PMID:
18782657
32.

Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast.

Jiang JC, Wawryn J, Shantha Kumara HM, Jazwinski SM.

Exp Gerontol. 2002 Aug-Sep;37(8-9):1023-30.

PMID:
12213553

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