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Items: 1 to 50 of 139

1.

Metabolic engineering of Escherichia coli for the production of butyric acid at high titer and productivity.

Wang L, Chauliac D, Moritz BE, Zhang G, Ingram LO, Shanmugam KT.

Biotechnol Biofuels. 2019 Mar 22;12:62. doi: 10.1186/s13068-019-1408-9. eCollection 2019.

2.

Simultaneous fermentation of biomass-derived sugars to ethanol by a co-culture of an engineered Escherichia coli and Saccharomyces cerevisiae.

Wang L, York SW, Ingram LO, Shanmugam KT.

Bioresour Technol. 2019 Feb;273:269-276. doi: 10.1016/j.biortech.2018.11.016. Epub 2018 Nov 7.

PMID:
30448678
3.

Fermentation of dihydroxyacetone by engineered Escherichia coli and Klebsiella variicola to products.

Wang L, Chauliac D, Rhee MS, Panneerselvam A, Ingram LO, Shanmugam KT.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4381-4386. doi: 10.1073/pnas.1801002115. Epub 2018 Apr 9.

4.

Phosphoric acid based pretreatment of switchgrass and fermentation of entire slurry to ethanol using a simplified process.

Wu W, Rondon V, Weeks K, Pullammanappallil P, Ingram LO, Shanmugam KT.

Bioresour Technol. 2018 Mar;251:171-180. doi: 10.1016/j.biortech.2017.12.041. Epub 2017 Dec 16.

PMID:
29274857
5.

Metabolic engineering of Bacillus subtilis for production of D-lactic acid.

Awasthi D, Wang L, Rhee MS, Wang Q, Chauliac D, Ingram LO, Shanmugam KT.

Biotechnol Bioeng. 2018 Feb;115(2):453-463. doi: 10.1002/bit.26472. Epub 2017 Oct 30.

PMID:
28986980
6.

Techno-economic analysis of ethanol production from sugarcane bagasse using a Liquefaction plus Simultaneous Saccharification and co-Fermentation process.

Gubicza K, Nieves IU, Sagues WJ, Barta Z, Shanmugam KT, Ingram LO.

Bioresour Technol. 2016 May;208:42-48. doi: 10.1016/j.biortech.2016.01.093. Epub 2016 Feb 1.

PMID:
26918837
7.
8.

Fermentation of sweet sorghum derived sugars to butyric acid at high titer and productivity by a moderate thermophile Clostridium thermobutyricum at 50°C.

Wang L, Ou MS, Nieves I, Erickson JE, Vermerris W, Ingram LO, Shanmugam KT.

Bioresour Technol. 2015 Dec;198:533-9. doi: 10.1016/j.biortech.2015.09.062. Epub 2015 Sep 26.

PMID:
26432057
9.

Removing chiral contamination of lactate solutions by selective metabolism of the D-enantiomer.

Chauliac D, Pullammanappallil PC, Ingram LO, Shanmugam KT.

Biotechnol Lett. 2015 Dec;37(12):2411-8. doi: 10.1007/s10529-015-1924-z. Epub 2015 Aug 14.

PMID:
26272390
10.

Pseudoepitheliomatous Hyperplasia: Relevance in Oral Pathology.

Sarangarajan R, Vedam VK, Sivadas G, Krishnaraj R, Sarangarajan A, Shanmugam KT.

J Int Oral Health. 2015 Jul;7(7):132-6. Review.

11.

Mutation in galP improved fermentation of mixed sugars to succinate using engineered Escherichia coli AS1600a and AM1 mineral salts medium.

Sawisit A, Jantama K, Zheng H, Yomano LP, York SW, Shanmugam KT, Ingram LO.

Bioresour Technol. 2015 Oct;193:433-41. doi: 10.1016/j.biortech.2015.06.108. Epub 2015 Jun 25.

PMID:
26159300
12.

DNA adducts-chemical addons.

Rajalakshmi TR, AravindhaBabu N, Shanmugam KT, Masthan KM.

J Pharm Bioallied Sci. 2015 Apr;7(Suppl 1):S197-9. doi: 10.4103/0975-7406.155901. Review.

13.

Combining treatments to improve the fermentation of sugarcane bagasse hydrolysates by ethanologenic Escherichia coli LY180.

Geddes R, Shanmugam KT, Ingram LO.

Bioresour Technol. 2015;189:15-22. doi: 10.1016/j.biortech.2015.03.141. Epub 2015 Mar 31.

PMID:
25864026
14.

Immunology of oral candidiasis.

Dineshshankar J, Sivakumar M, Karthikeyan M, Udayakumar P, Shanmugam KT, Kesavan G.

J Pharm Bioallied Sci. 2014 Jul;6(Suppl 1):S9-S12. doi: 10.4103/0975-7406.137251. Review.

15.

Polyamine transporters and polyamines increase furfural tolerance during xylose fermentation with ethanologenic Escherichia coli strain LY180.

Geddes RD, Wang X, Yomano LP, Miller EN, Zheng H, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2014 Oct;80(19):5955-64. doi: 10.1128/AEM.01913-14. Epub 2014 Jul 25.

16.

Dental caries vaccine - a possible option?

Kt S, Kmk M, N B, Jimson S, R S.

J Clin Diagn Res. 2013 Jun;7(6):1250-3. doi: 10.7860/JCDR/2013/5246.3053. Epub 2013 Apr 11.

17.

Improving Escherichia coli FucO for furfural tolerance by saturation mutagenesis of individual amino acid positions.

Zheng H, Wang X, Yomano LP, Geddes RD, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2013 May;79(10):3202-8. doi: 10.1128/AEM.00149-13. Epub 2013 Mar 8.

18.

Engineering furfural tolerance in Escherichia coli improves the fermentation of lignocellulosic sugars into renewable chemicals.

Wang X, Yomano LP, Lee JY, York SW, Zheng H, Mullinnix MT, Shanmugam KT, Ingram LO.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4021-6. doi: 10.1073/pnas.1217958110. Epub 2013 Feb 19.

19.

Seed train development for the fermentation of bagasse from sweet sorghum and sugarcane using a simplified fermentation process.

Geddes CC, Mullinnix MT, Nieves IU, Hoffman RW, Sagues WJ, York SW, Shanmugam KT, Erickson JE, Vermerris WE, Ingram LO.

Bioresour Technol. 2013 Jan;128:716-24. doi: 10.1016/j.biortech.2012.09.121. Epub 2012 Oct 16.

PMID:
23375156
20.

Complete genome sequence of Paenibacillus sp. strain JDR-2.

Chow V, Nong G, St John FJ, Rice JD, Dickstein E, Chertkov O, Bruce D, Detter C, Brettin T, Han J, Woyke T, Pitluck S, Nolan M, Pati A, Martin J, Copeland A, Land ML, Goodwin L, Jones JB, Ingram LO, Shanmugam KT, Preston JF.

Stand Genomic Sci. 2012 Mar 19;6(1):1-10. doi: 10.4056/sigs.2374349. Epub 2012 Mar 5.

21.

Complete Genome Sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1.

Rhee MS, Moritz BE, Xie G, Glavina Del Rio T, Dalin E, Tice H, Bruce D, Goodwin L, Chertkov O, Brettin T, Han C, Detter C, Pitluck S, Land ML, Patel M, Ou M, Harbrucker R, Ingram LO, Shanmugam KT.

Stand Genomic Sci. 2011 Dec 31;5(3):331-40. doi: 10.4056/sigs.2365342. Epub 2011 Dec 22.

22.

Increase in furfural tolerance in ethanologenic Escherichia coli LY180 by plasmid-based expression of thyA.

Zheng H, Wang X, Yomano LP, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2012 Jun;78(12):4346-52. doi: 10.1128/AEM.00356-12. Epub 2012 Apr 13.

23.

Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH.

Sun Z, Do PM, Rhee MS, Govindasamy L, Wang Q, Ingram LO, Shanmugam KT.

Microbiology. 2012 May;158(Pt 5):1350-8. doi: 10.1099/mic.0.055590-0. Epub 2012 Feb 16.

PMID:
22343352
24.

Increased furan tolerance in Escherichia coli due to a cryptic ucpA gene.

Wang X, Miller EN, Yomano LP, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2012 Apr;78(7):2452-5. doi: 10.1128/AEM.07783-11. Epub 2012 Jan 20.

25.

Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes.

Turner PC, Yomano LP, Jarboe LR, York SW, Baggett CL, Moritz BE, Zentz EB, Shanmugam KT, Ingram LO.

J Ind Microbiol Biotechnol. 2012 Apr;39(4):629-39. doi: 10.1007/s10295-011-1052-2. Epub 2011 Nov 11.

PMID:
22075923
26.

Evolution of D-lactate dehydrogenase activity from glycerol dehydrogenase and its utility for D-lactate production from lignocellulose.

Wang Q, Ingram LO, Shanmugam KT.

Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18920-5. doi: 10.1073/pnas.1111085108. Epub 2011 Nov 7.

27.

Isolation, characterization and evolution of a new thermophilic Bacillus licheniformis for lactic acid production in mineral salts medium.

Wang Q, Zhao X, Chamu J, Shanmugam KT.

Bioresour Technol. 2011 Sep;102(17):8152-8. doi: 10.1016/j.biortech.2011.06.003. Epub 2011 Jun 6.

PMID:
21704521
28.

Increased furfural tolerance due to overexpression of NADH-dependent oxidoreductase FucO in Escherichia coli strains engineered for the production of ethanol and lactate.

Wang X, Miller EN, Yomano LP, Zhang X, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2011 Aug;77(15):5132-40. doi: 10.1128/AEM.05008-11. Epub 2011 Jun 17.

29.

Injection of air into the headspace improves fermentation of phosphoric acid pretreated sugarcane bagasse by Escherichia coli MM170.

Nieves IU, Geddes CC, Mullinnix MT, Hoffman RW, Tong Z, Castro E, Shanmugam KT, Ingram LO.

Bioresour Technol. 2011 Jul;102(13):6959-65. doi: 10.1016/j.biortech.2011.04.036. Epub 2011 Apr 15.

PMID:
21531547
30.

Simplified process for ethanol production from sugarcane bagasse using hydrolysate-resistant Escherichia coli strain MM160.

Geddes CC, Mullinnix MT, Nieves IU, Peterson JJ, Hoffman RW, York SW, Yomano LP, Miller EN, Shanmugam KT, Ingram LO.

Bioresour Technol. 2011 Feb;102(3):2702-11. doi: 10.1016/j.biortech.2010.10.143. Epub 2010 Nov 4.

PMID:
21111615
31.

L-malate production by metabolically engineered Escherichia coli.

Zhang X, Wang X, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2011 Jan;77(2):427-34. doi: 10.1128/AEM.01971-10. Epub 2010 Nov 19.

32.

L: (+)-Lactic acid production from non-food carbohydrates by thermotolerant Bacillus coagulans.

Ou MS, Ingram LO, Shanmugam KT.

J Ind Microbiol Biotechnol. 2011 May;38(5):599-605. doi: 10.1007/s10295-010-0796-4. Epub 2010 Aug 9.

PMID:
20694852
33.

Optimizing cellulase usage for improved mixing and rheological properties of acid-pretreated sugarcane bagasse.

Geddes CC, Peterson JJ, Mullinnix MT, Svoronos SA, Shanmugam KT, Ingram LO.

Bioresour Technol. 2010 Dec;101(23):9128-36. doi: 10.1016/j.biortech.2010.07.040. Epub 2010 Jul 14.

PMID:
20678927
34.

Physiological and fermentation properties of Bacillus coagulans and a mutant lacking fermentative lactate dehydrogenase activity.

Su Y, Rhee MS, Ingram LO, Shanmugam KT.

J Ind Microbiol Biotechnol. 2011 Mar;38(3):441-50. doi: 10.1007/s10295-010-0788-4. Epub 2010 Jul 31.

PMID:
20677017
35.

YqhC regulates transcription of the adjacent Escherichia coli genes yqhD and dkgA that are involved in furfural tolerance.

Turner PC, Miller EN, Jarboe LR, Baggett CL, Shanmugam KT, Ingram LO.

J Ind Microbiol Biotechnol. 2011 Mar;38(3):431-9. doi: 10.1007/s10295-010-0787-5. Epub 2010 Jul 30.

PMID:
20676725
36.

Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology.

Jarboe LR, Zhang X, Wang X, Moore JC, Shanmugam KT, Ingram LO.

J Biomed Biotechnol. 2010;2010:761042. doi: 10.1155/2010/761042. Epub 2010 Apr 6. Review.

37.

Fermentation of glycerol to succinate by metabolically engineered strains of Escherichia coli.

Zhang X, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2010 Apr;76(8):2397-401. doi: 10.1128/AEM.02902-09. Epub 2010 Feb 12.

38.

Metabolic flux control at the pyruvate node in an anaerobic Escherichia coli strain with an active pyruvate dehydrogenase.

Wang Q, Ou MS, Kim Y, Ingram LO, Shanmugam KT.

Appl Environ Microbiol. 2010 Apr;76(7):2107-14. doi: 10.1128/AEM.02545-09. Epub 2010 Jan 29.

39.

Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli.

Zhang X, Jantama K, Moore JC, Jarboe LR, Shanmugam KT, Ingram LO.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20180-5. doi: 10.1073/pnas.0905396106. Epub 2009 Nov 16.

40.

Optimizing the saccharification of sugar cane bagasse using dilute phosphoric acid followed by fungal cellulases.

Geddes CC, Peterson JJ, Roslander C, Zacchi G, Mullinnix MT, Shanmugam KT, Ingram LO.

Bioresour Technol. 2010 Mar;101(6):1851-7. doi: 10.1016/j.biortech.2009.09.070. Epub 2009 Oct 31.

PMID:
19880314
41.

Reengineering Escherichia coli for Succinate Production in Mineral Salts Medium.

Zhang X, Jantama K, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2009 Dec;75(24):7807-13. doi: 10.1128/AEM.01758-09. Epub 2009 Oct 16.

42.

Furfural inhibits growth by limiting sulfur assimilation in ethanologenic Escherichia coli strain LY180.

Miller EN, Jarboe LR, Turner PC, Pharkya P, Yomano LP, York SW, Nunn D, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2009 Oct;75(19):6132-41. doi: 10.1128/AEM.01187-09. Epub 2009 Aug 14.

43.

Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.

Kajiya M, Sato K, Silva MJ, Ouhara K, Do PM, Shanmugam KT, Kawai T.

Biochem Biophys Res Commun. 2009 Aug 21;386(2):316-21. doi: 10.1016/j.bbrc.2009.06.024. Epub 2009 Jun 10.

PMID:
19523450
44.

Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli.

Yomano LP, York SW, Shanmugam KT, Ingram LO.

Biotechnol Lett. 2009 Sep;31(9):1389-98. doi: 10.1007/s10529-009-0011-8. Epub 2009 May 21.

45.

Silencing of NADPH-dependent oxidoreductase genes (yqhD and dkgA) in furfural-resistant ethanologenic Escherichia coli.

Miller EN, Jarboe LR, Yomano LP, York SW, Shanmugam KT, Ingram LO.

Appl Environ Microbiol. 2009 Jul;75(13):4315-23. doi: 10.1128/AEM.00567-09. Epub 2009 May 8.

46.

Engineering Escherichia coli for fermentative dihydrogen production: potential role of NADH-ferredoxin oxidoreductase from the hydrogenosome of anaerobic protozoa.

Do PM, Angerhofer A, Hrdy I, Bardonova L, Ingram LO, Shanmugam KT.

Appl Biochem Biotechnol. 2009 May;153(1-3):21-33. doi: 10.1007/s12010-008-8508-5. Epub 2009 Jan 27.

PMID:
19172236
47.

Thermophilic Bacillus coagulans requires less cellulases for simultaneous saccharification and fermentation of cellulose to products than mesophilic microbial biocatalysts.

Ou MS, Mohammed N, Ingram LO, Shanmugam KT.

Appl Biochem Biotechnol. 2009 May;155(1-3):379-85. doi: 10.1007/s12010-008-8509-4. Epub 2009 Jan 21.

PMID:
19156365
48.

Eliminating side products and increasing succinate yields in engineered strains of Escherichia coli C.

Jantama K, Zhang X, Moore JC, Shanmugam KT, Svoronos SA, Ingram LO.

Biotechnol Bioeng. 2008 Dec 1;101(5):881-93. doi: 10.1002/bit.22005.

PMID:
18781696
49.

Re-engineering Escherichia coli for ethanol production.

Yomano LP, York SW, Zhou S, Shanmugam KT, Ingram LO.

Biotechnol Lett. 2008 Dec;30(12):2097-103. doi: 10.1007/s10529-008-9821-3. Epub 2008 Sep 5.

PMID:
18773150
50.

Dihydrolipoamide dehydrogenase mutation alters the NADH sensitivity of pyruvate dehydrogenase complex of Escherichia coli K-12.

Kim Y, Ingram LO, Shanmugam KT.

J Bacteriol. 2008 Jun;190(11):3851-8. doi: 10.1128/JB.00104-08. Epub 2008 Mar 28.

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