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Items: 1 to 50 of 143

1.

Loss of myeloid-specific protein phosphatase 2A enhances lung injury and fibrosis and results in IL-10-dependent sensitization of epithelial cell apoptosis.

Sun L, Hult EM, Cornell TT, Kim KK, Shanley TP, Wilke CA, Agarwal M, Gurczynski SJ, Moore BB, Dahmer MK.

Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1035-L1048. doi: 10.1152/ajplung.00299.2018. Epub 2019 Mar 6.

PMID:
30838865
2.

miR-144-mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability.

Siddiqui MR, Akhtar S, Shahid M, Tauseef M, McDonough K, Shanley TP.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):257-265. doi: 10.1165/rcmb.2018-0235OC.

PMID:
30811958
3.

Hemolysis During Pediatric Extracorporeal Membrane Oxygenation: Associations With Circuitry, Complications, and Mortality.

Dalton HJ, Cashen K, Reeder RW, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2018 Nov;19(11):1067-1076. doi: 10.1097/PCC.0000000000001709.

PMID:
30106767
4.

Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation.

Cashen K, Reeder R, Dalton HJ, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Tamburro R, Meert KL.

Perfusion. 2018 Sep;33(6):472-482. doi: 10.1177/0267659118766436. Epub 2018 Apr 11.

5.

RBC Transfusion Practice in Pediatric Extracorporeal Membrane Oxygenation Support.

Muszynski JA, Reeder RW, Hall MW, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Meert KL, Dean JM, Jenkins T, Tamburro RF, Dalton HJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Crit Care Med. 2018 Jun;46(6):e552-e559. doi: 10.1097/CCM.0000000000003086.

6.

Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors.

Cashen K, Reeder R, Dalton HJ, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Tamburro R, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2018 Mar;19(3):245-253. doi: 10.1097/PCC.0000000000001439.

7.

Cognitive Development One Year After Infantile Critical Pertussis.

Berger JT, Villalobos ME, Clark AE, Holubkov R, Pollack MM, Berg RA, Carcillo JA, Dalton H, Harrison R, Meert KL, Newth CJL, Shanley TP, Wessel DL, Anand KJS, Zimmerman JJ, Sanders RC Jr, Liu T, Burr JS, Willson DF, Doctor A, Dean JM, Jenkins TL, Nicholson CE; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Pediatr Crit Care Med. 2018 Feb;19(2):89-97. doi: 10.1097/PCC.0000000000001367.

8.

Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol?

Newth CJL, Sward KA, Khemani RG, Page K, Meert KL, Carcillo JA, Shanley TP, Moler FW, Pollack MM, Dalton HJ, Wessel DL, Berger JT, Berg RA, Harrison RE, Holubkov R, Doctor A, Dean JM, Jenkins TL, Nicholson CE; Eunice Kennedy Shriver National Institute for Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2017 Nov;18(11):e521-e529. doi: 10.1097/PCC.0000000000001319.

9.

Potential Acceptability of a Pediatric Ventilator Management Computer Protocol.

Sward KA, Newth CJL, Khemani RG, Page K, Meert KL, Carcillo JA, Shanley TP, Moler FW, Pollack MM, Dalton HJ, Wessel DL, Berger JT, Berg RA, Harrison RE, Doctor A, Dean JM, Holobkov R, Jenkins TL, Nicholson CE; Eunice Kennedy Shriver National Institute for Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2017 Nov;18(11):1027-1034. doi: 10.1097/PCC.0000000000001331.

10.

Education and training of clinical and translational study investigators and research coordinators: A competency-based approach.

Calvin-Naylor NA, Jones CT, Wartak MM, Blackwell K, Davis JM, Divecha R, Ellerbeck EF, Kieburtz K, Koziel MJ, Luzuriaga K, Maddox J, Needler NA, Murphy S, Pemberton K, Radovich C, Rubinstein EP, Selker HP, Tenaerts P, Unsworth K, Wilson K, Wright JE, Barohn R, Shanley TP.

J Clin Transl Sci. 2017 Feb;1(1):16-25. doi: 10.1017/cts.2016.2. Epub 2017 Jan 13.

11.

Functional Status of Neonatal and Pediatric Patients After Extracorporeal Membrane Oxygenation.

Cashen K, Reeder R, Dalton HJ, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Jenkins T, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2017 Jun;18(6):561-570. doi: 10.1097/PCC.0000000000001155.

12.

Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome.

Carcillo JA, Podd B, Aneja R, Weiss SL, Hall MW, Cornell TT, Shanley TP, Doughty LA, Nguyen TC.

Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S32-S45. doi: 10.1097/PCC.0000000000001052. Review.

13.

The Missing -Omes: Proposing Social and Environmental Nomenclature in Precision Medicine.

Davis MM, Shanley TP.

Clin Transl Sci. 2017 Mar;10(2):64-66. doi: 10.1111/cts.12453. Epub 2017 Feb 26. No abstract available.

14.

Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge.

Sun L, Pham TT, Cornell TT, McDonough KL, McHugh WM, Blatt NB, Dahmer MK, Shanley TP.

J Immunol. 2017 Jan 1;198(1):404-416. Epub 2016 Nov 21.

15.

Protein phosphatase 2A activation attenuates inflammation in murine models of acute lung injury.

McHugh WM, Russell WW, Fleszar AJ, Rodenhouse PE, Rietberg SP, Sun L, Shanley TP, Cornell TT.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L903-L912. doi: 10.1152/ajplung.00007.2016. Epub 2016 Sep 16.

16.

Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post Hoc Analysis of the CRISIS Trial.

Carcillo JA, Dean JM, Holubkov R, Berger J, Meert KL, Anand KJ, Zimmerman J, Newth CJ, Harrison R, Burr J, Willson DF, Nicholson C, Bell MJ, Berg RA, Shanley TP, Heidemann SM, Dalton H, Jenkins TL, Doctor A, Webster A; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Infect Dis J. 2016 Nov;35(11):1182-1186.

17.

Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial.

Carcillo JA, Dean JM, Holubkov R, Berger J, Meert KL, Anand KJS, Zimmerman JJ, Newth CJL, Harrison R, Burr J, Willson DF, Nicholson C, Bell MJ, Berg RA, Shanley TP, Heidemann SM, Dalton H, Jenkins TL, Doctor A, Webster A, Tamburro RF; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN).

JPEN J Parenter Enteral Nutr. 2017 Nov;41(8):1325-1335. doi: 10.1177/0148607116670377. Epub 2016 Sep 22.

18.

Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure.

Oh BR, Chen P, Nidetz R, McHugh W, Fu J, Shanley TP, Cornell TT, Kurabayashi K.

ACS Sens. 2016 Jul 22;1(7):941-948. Epub 2016 Jun 22.

19.

Language Analysis as a Window to Bereaved Parents' Emotions During a Parent-Physician Bereavement Meeting.

Eggly S, Manning MA, Slatcher RB, Berg RA, Wessel DL, Newth CJ, Shanley TP, Harrison R, Dalton H, Dean JM, Doctor A, Jenkins T, Meert KL.

J Lang Soc Psychol. 2015 Mar;34(2):181-199. Epub 2014 Oct 30.

20.

Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs.

Berg RA, Nadkarni VM, Clark AE, Moler F, Meert K, Harrison RE, Newth CJ, Sutton RM, Wessel DL, Berger JT, Carcillo J, Dalton H, Heidemann S, Shanley TP, Zuppa AF, Doctor A, Tamburro RF, Jenkins TL, Dean JM, Holubkov R, Pollack MM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Crit Care Med. 2016 Apr;44(4):798-808. doi: 10.1097/CCM.0000000000001484.

21.

Differential expression of the Nrf2-linked genes in pediatric septic shock.

Grunwell JR, Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Howard K, Frank E, Harmon K, Wong HR.

Crit Care. 2015 Sep 17;19:327. doi: 10.1186/s13054-015-1052-0.

22.

Study of Protein Phosphatase 2A (PP2A) Activity in LPS-Induced Tolerance Using Fluorescence-Based and Immunoprecipitation-Aided Methodology.

Sun L, Ii AL, Pham TT, Shanley TP.

Biomolecules. 2015 Jun 29;5(3):1284-301. doi: 10.3390/biom5031284.

23.

Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA.

Yu ZT, Guan H, Cheung MK, McHugh WM, Cornell TT, Shanley TP, Kurabayashi K, Fu J.

Sci Rep. 2015 Jun 15;5:11339. doi: 10.1038/srep11339.

24.

A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury.

Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Dawson E, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Lindsell CJ.

Crit Care Med. 2015 Aug;43(8):1646-53. doi: 10.1097/CCM.0000000000001079.

25.

Meaning making during parent-physician bereavement meetings after a child's death.

Meert KL, Eggly S, Kavanaugh K, Berg RA, Wessel DL, Newth CJ, Shanley TP, Harrison R, Dalton H, Dean JM, Doctor A, Jenkins T, Park CL.

Health Psychol. 2015 Apr;34(4):453-61. doi: 10.1037/hea0000153.

26.

Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network.

Frey LJ, Sward KA, Newth CJ, Khemani RG, Cryer ME, Thelen JL, Enriquez R, Shaoyu S, Pollack MM, Harrison RE, Meert KL, Berg RA, Wessel DL, Shanley TP, Dalton H, Carcillo J, Jenkins TL, Dean JM.

J Am Med Inform Assoc. 2015 Nov;22(6):1271-6. doi: 10.1093/jamia/ocv009. Epub 2015 Mar 21.

27.

Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays.

Chen P, Chung MT, McHugh W, Nidetz R, Li Y, Fu J, Cornell TT, Shanley TP, Kurabayashi K.

ACS Nano. 2015;9(4):4173-81. doi: 10.1021/acsnano.5b00396. Epub 2015 Mar 23.

28.

Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses.

Ashbrook MJ, McDonough KL, Pituch JJ, Christopherson PL, Cornell TT, Selewski DT, Shanley TP, Blatt NB.

Clin Exp Immunol. 2015 Jun;180(3):520-30. doi: 10.1111/cei.12591. Epub 2015 Apr 19.

29.

Refractory hypoxemia caused by hepatopulmonary syndrome: a case report.

Govindan ML, Kuo KW, Mahani MG, Shanley TP.

J Med Case Rep. 2014 Dec 10;8:418. doi: 10.1186/1752-1947-8-418.

30.

Developing a clinically feasible personalized medicine approach to pediatric septic shock.

Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):309-15. doi: 10.1164/rccm.201410-1864OC.

31.

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock.

Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Wong HR.

Crit Care. 2014 Nov 19;18(6):623. doi: 10.1186/s13054-014-0623-9.

32.

Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.

Atkinson SJ, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Weiss SL, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Lahni P, Lindsell CJ, Wong HR.

PLoS One. 2014 Nov 11;9(11):e112702. doi: 10.1371/journal.pone.0112702. eCollection 2014.

33.

Validation of the KDIGO acute kidney injury criteria in a pediatric critical care population.

Selewski DT, Cornell TT, Heung M, Troost JP, Ehrmann BJ, Lombel RM, Blatt NB, Luckritz K, Hieber S, Gajarski R, Kershaw DB, Shanley TP, Gipson DS.

Intensive Care Med. 2014 Oct;40(10):1481-8. doi: 10.1007/s00134-014-3391-8. Epub 2014 Jul 31.

PMID:
25079008
34.

Time for a neonatal-specific consensus definition for sepsis.

Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA.

Pediatr Crit Care Med. 2014 Jul;15(6):523-8. doi: 10.1097/PCC.0000000000000157. Review.

35.

Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock.

Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Weiss SL, Shanley TP, Bigham MT, Banschbach S, Beckman E, Harmon K, Zimmerman JJ.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):940-6. doi: 10.1164/rccm.201401-0171OC.

36.

The temporal version of the pediatric sepsis biomarker risk model.

Wong HR, Weiss SL, Giuliano JS Jr, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Harmon K, Lahni P, Lindsell CJ.

PLoS One. 2014 Mar 13;9(3):e92121. doi: 10.1371/journal.pone.0092121. eCollection 2014.

37.

Integrated nanoplasmonic sensing for cellular functional immunoanalysis using human blood.

Oh BR, Huang NT, Chen W, Seo JH, Chen P, Cornell TT, Shanley TP, Fu J, Kurabayashi K.

ACS Nano. 2014 Mar 25;8(3):2667-76. doi: 10.1021/nn406370u. Epub 2014 Feb 25.

38.

Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.

Wong HR, Weiss SL, Giuliano JS Jr, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Lahni P, Hart K, Lindsell CJ.

PLoS One. 2014 Jan 29;9(1):e86242. doi: 10.1371/journal.pone.0086242. eCollection 2014.

39.

Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion.

Dolgachev VA, Yu B, Sun L, Shanley TP, Raghavendran K, Hemmila MR.

Shock. 2014 Apr;41(4):301-10. doi: 10.1097/SHK.0000000000000123.

40.

Biology of sepsis: its relevance to pediatric nephrology.

Blatt NB, Srinivasan S, Mottes T, Shanley MM, Shanley TP.

Pediatr Nephrol. 2014 Dec;29(12):2273-87. doi: 10.1007/s00467-013-2677-3. Epub 2014 Jan 10. Review.

41.

Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis.

Abulebda K, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Weiss SL, Chopra A, Banschbach S, Beckman E, Lindsell CJ, Wong HR.

Crit Care Med. 2014 Feb;42(2):397-403. doi: 10.1097/CCM.0b013e3182a64607.

42.

Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child's death in the PICU.

Meert KL, Eggly S, Berg RA, Wessel DL, Newth CJ, Shanley TP, Harrison R, Dalton H, Clark AE, Dean JM, Doctor A, Nicholson CE; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Crit Care Med. 2014 Jan;42(1):148-57. doi: 10.1097/CCM.0b013e3182a26ff3.

43.

Improving delivery of continuous renal replacement therapy: impact of a simulation-based educational intervention.

Mottes T, Owens T, Niedner M, Juno J, Shanley TP, Heung M.

Pediatr Crit Care Med. 2013 Oct;14(8):747-54. doi: 10.1097/PCC.0b013e318297626e.

PMID:
23863823
44.

The use of extracorporeal membrane oxygenation in pediatric patients with sickle cell disease.

Kuo KW, Cornell TT, Shanley TP, Odetola FO, Annich GM.

Perfusion. 2013 Sep;28(5):424-32. doi: 10.1177/0267659113485873. Epub 2013 Apr 29. Review.

45.

The ideal time interval for critical care severity-of-illness assessment.

Pollack MM, Dean JM, Butler J, Holubkov R, Doctor A, Meert KL, Newth CJ, Berg RA, Moler F, Dalton H, Wessel DL, Berger J, Harrison RE, Carcillo JA, Shanley TP, Nicholson CE.

Pediatr Crit Care Med. 2013 Jun;14(5):448-53. doi: 10.1097/PCC.0b013e31828a7270.

46.

Public participation in, and awareness about, medical research opportunities in the era of clinical and translational research.

Davis MM, Clark SJ, Butchart AT, Singer DC, Shanley TP, Gipson DS.

Clin Transl Sci. 2013 Apr;6(2):88-93. doi: 10.1111/cts.12019. Epub 2013 Jan 14.

47.

Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation.

Sun L, Cornell TT, LeVine A, Berlin AA, Hinkovska-Galcheva V, Fleszar AJ, Lukacs NW, Shanley TP.

Clin Exp Immunol. 2013 May;172(2):263-79. doi: 10.1111/cei.12059.

48.

Critical pertussis illness in children: a multicenter prospective cohort study.

Berger JT, Carcillo JA, Shanley TP, Wessel DL, Clark A, Holubkov R, Meert KL, Newth CJ, Berg RA, Heidemann S, Harrison R, Pollack M, Dalton H, Harvill E, Karanikas A, Liu T, Burr JS, Doctor A, Dean JM, Jenkins TL, Nicholson CE; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2013 May;14(4):356-65. doi: 10.1097/PCC.0b013e31828a70fe.

49.

Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages.

Ray D, Shukla S, Allam US, Helman A, Ramanand SG, Tran L, Bassetti M, Krishnamurthy PM, Rumschlag M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK, Zhang M, Lawrence TS.

PLoS One. 2013;8(2):e57290. doi: 10.1371/journal.pone.0057290. Epub 2013 Feb 28.

50.

Surface-micromachined microfiltration membranes for efficient isolation and functional immunophenotyping of subpopulations of immune cells.

Chen W, Huang NT, Oh B, Lam RHW, Fan R, Cornell TT, Shanley TP, Kurabayashi K, Fu J.

Adv Healthc Mater. 2013 Jul;2(7):965-975. doi: 10.1002/adhm.201200378. Epub 2013 Jan 20.

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