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Items: 41

1.

The impact of surgery on survival after progression of glioblastoma: A retrospective cohort analysis of a contemporary patient population.

Sastry RA, Shankar GM, Gerstner ER, Curry WT.

J Clin Neurosci. 2018 Jul;53:41-47. doi: 10.1016/j.jocn.2018.04.004. Epub 2018 Apr 19.

PMID:
29680441
2.

Implication of Biomarker Mutations for Predicting Survival in Patients With Metastatic Lung Cancer to The Spine.

Choi BD, Shankar GM, Sivaganesan A, Van Beaver LA, Oh K, Shin JH.

Spine (Phila Pa 1976). 2018 Apr 12. doi: 10.1097/BRS.0000000000002683. [Epub ahead of print]

PMID:
29652780
3.

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas.

Juratli TA, Thiede C, Koerner MVA, Tummala SS, Daubner D, Shankar GM, Williams EA, Martinez-Lage M, Soucek S, Robel K, Penson T, Krause M, Appold S, Meinhardt M, Pinzer T, Miller JJ, Krex D, Ely HA, Silverman IM, Christiansen J, Schackert G, Wakimoto H, Kirsch M, Brastianos PK, Cahill DP.

Oncotarget. 2017 Nov 24;8(65):109228-109237. doi: 10.18632/oncotarget.22650. eCollection 2017 Dec 12.

4.

Liquid biopsy for brain tumors.

Shankar GM, Balaj L, Stott SL, Nahed B, Carter BS.

Expert Rev Mol Diagn. 2017 Oct;17(10):943-947. doi: 10.1080/14737159.2017.1374854. Epub 2017 Sep 6. Review.

5.

The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.

Tateishi K, Higuchi F, Miller JJ, Koerner MVA, Lelic N, Shankar GM, Tanaka S, Fisher DE, Batchelor TT, Iafrate AJ, Wakimoto H, Chi AS, Cahill DP.

Cancer Res. 2017 Aug 1;77(15):4102-4115. doi: 10.1158/0008-5472.CAN-16-2263. Epub 2017 Jun 16.

PMID:
28625978
6.

BAP1 mutations in high-grade meningioma: implications for patient care.

Shankar GM, Santagata S.

Neuro Oncol. 2017 Oct 19;19(11):1447-1456. doi: 10.1093/neuonc/nox094. Review.

PMID:
28482042
7.

The role of revision surgery and adjuvant therapy following subtotal resection of osteosarcoma of the spine: a systematic review with meta-analysis.

Shankar GM, Clarke MJ, Ailon T, Rhines LD, Patel SR, Sahgal A, Laufer I, Chou D, Bilsky MH, Sciubba DM, Fehlings MG, Fisher CG, Gokaslan ZL, Shin JH.

J Neurosurg Spine. 2017 Jul;27(1):97-104. doi: 10.3171/2016.12.SPINE16995. Epub 2017 Apr 28. Review.

PMID:
28452631
8.

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.

Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, Batchelor TT, Ligon KL, Ligon AH, Meyerson M, Dunn IF, Beroukhim R, Louis DN, Perry A, Carter SL, Giannini C, Curry WT Jr, Cahill DP, Barker FG 2nd, Brastianos PK, Santagata S.

Neuro Oncol. 2017 Apr 1;19(4):535-545. doi: 10.1093/neuonc/now235.

9.

Effect of Immunotherapy Status on Outcomes in Patients With Metastatic Melanoma to the Spine.

Shankar GM, Choi BD, Grannan BL, Oh K, Shin JH.

Spine (Phila Pa 1976). 2017 Jun 15;42(12):E721-E725. doi: 10.1097/BRS.0000000000001993.

PMID:
27879568
10.

Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting With Complete Paraplegia.

Friedman GN, Grannan BL, Yanamadala V, Shankar GM, Dewitt JC, Puthenpura V, Koffie RM, Macdonald SM, Ebb DH, Frosch MP, Duhaime AC.

J Pediatr Hematol Oncol. 2016 Nov;38(8):e286-e290.

PMID:
27403775
11.

Metastatic adrenal cortical carcinoma to T12 vertebrae.

Lee D, Yanamadala V, Shankar GM, Shin JH.

J Clin Neurosci. 2016 May;27:166-9. doi: 10.1016/j.jocn.2015.11.009. Epub 2016 Jan 4.

PMID:
26765762
12.

Spinal cord glioblastoma: 25years of experience from a single institution.

Yanamadala V, Koffie RM, Shankar GM, Kumar JI, Buchlak QD, Puthenpura V, Frosch MP, Gudewicz TM, Borges LF, Shin JH.

J Clin Neurosci. 2016 May;27:138-41. doi: 10.1016/j.jocn.2015.11.011. Epub 2016 Jan 2.

PMID:
26755453
13.

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.

Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, Cahill DP, Santagata S, Curry WT Jr, Barker FG 2nd.

J Natl Cancer Inst. 2015 Oct 23;108(2). pii: djv310. doi: 10.1093/jnci/djv310. Print 2016 Feb.

14.

BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology.

Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, Hawkins CE, Louis DN, Cahill DP, Curry WT, Meyerson M.

Acta Neuropathol. 2016 Jan;131(1):147-50. No abstract available.

15.

Quercetin and Tryptanthrin: Two Broad Spectrum Anticancer Agents for Future Chemotherapeutic Interventions.

Shankar GM, Antony J, Anto RJ.

Enzymes. 2015;37:43-72. doi: 10.1016/bs.enz.2015.05.001. Epub 2015 Jul 2.

PMID:
26298455
16.

Rapid Intraoperative Molecular Characterization of Glioma.

Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, Sullivan RJ, Cherniack AD, Garraway LA, Stemmer-Rachamimov A, Reardon DA, Wen PY, Brastianos PK, Curry WT, Barker FG 2nd, Hahn WC, Nahed BV, Ligon KL, Louis DN, Cahill DP, Meyerson M.

JAMA Oncol. 2015 Aug;1(5):662-7. doi: 10.1001/jamaoncol.2015.0917.

17.

PLEKHA5: A Key to Unlock the Blood-Brain Barrier?

Eisele SC, Gill CM, Shankar GM, Brastianos PK.

Clin Cancer Res. 2015 May 1;21(9):1978-80. doi: 10.1158/1078-0432.CCR-14-2604. Epub 2015 Mar 16.

18.

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation.

Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, Lawrence MS, Cibulskis K, Thorner AR, Van Hummelen P, Stemmer-Rachamimov AO, Batchelor TT, Carter SL, Hoang MP, Santagata S, Louis DN, Barker FG, Meyerson M, Getz G, Brastianos PK, Cahill DP.

Acta Neuropathol Commun. 2014 Dec 24;2:167. doi: 10.1186/s40478-014-0167-x.

19.

Primary CNS lymphoma: the role of resection.

Shankar GM, Barker FG 2nd.

Oncology (Williston Park). 2014 Jul;28(7):637-8, 640, 642. No abstract available.

20.

Secreted amyloid β-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity.

Welzel AT, Maggio JE, Shankar GM, Walker DE, Ostaszewski BL, Li S, Klyubin I, Rowan MJ, Seubert P, Walsh DM, Selkoe DJ.

Biochemistry. 2014 Jun 24;53(24):3908-21.

21.

Transient aqueductal occlusion in intracerebral haemorrhage.

Diamond EL, Kimchi EY, Shankar GM, Silverman SB.

Pract Neurol. 2012 Dec;12(6):388-9. doi: 10.1136/practneurol-2011-000174. No abstract available.

PMID:
23144305
22.

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia.

Fu H, Liu B, Frost JL, Hong S, Jin M, Ostaszewski B, Shankar GM, Costantino IM, Carroll MC, Mayadas TN, Lemere CA.

Glia. 2012 May;60(6):993-1003. doi: 10.1002/glia.22331. Epub 2012 Mar 21.

23.

Cholesterol level and statin use in Alzheimer disease: II. Review of human trials and recommendations.

Shepardson NE, Shankar GM, Selkoe DJ.

Arch Neurol. 2011 Nov;68(11):1385-92. doi: 10.1001/archneurol.2011.242. Review.

24.

Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies.

Shepardson NE, Shankar GM, Selkoe DJ.

Arch Neurol. 2011 Oct;68(10):1239-44. doi: 10.1001/archneurol.2011.203. Review.

25.

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.

Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ.

J Neurosci. 2011 May 4;31(18):6627-38. doi: 10.1523/JNEUROSCI.0203-11.2011.

26.

Isolation of low-n amyloid β-protein oligomers from cultured cells, CSF, and brain.

Shankar GM, Welzel AT, McDonald JM, Selkoe DJ, Walsh DM.

Methods Mol Biol. 2011;670:33-44. doi: 10.1007/978-1-60761-744-0_3.

PMID:
20967581
27.

Composite ganglioneuroma-paraganglioma of the filum terminale.

Shankar GM, Chen L, Kim AH, Ross GL, Folkerth RD, Friedlander RM.

J Neurosurg Spine. 2010 Jun;12(6):709-13. doi: 10.3171/2009.12.SPINE09482.

PMID:
20515359
28.

How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity?

Li S, Shankar GM, Selkoe DJ.

Front Cell Neurosci. 2010 Mar 19;4:5. doi: 10.3389/fncel.2010.00005. eCollection 2010. No abstract available.

29.

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM; Medical Research Council Cognitive Function and Ageing Study.

Brain. 2010 May;133(Pt 5):1328-41. doi: 10.1093/brain/awq065. Epub 2010 Apr 19.

30.

Alzheimer's disease: synaptic dysfunction and Abeta.

Shankar GM, Walsh DM.

Mol Neurodegener. 2009 Nov 23;4:48. doi: 10.1186/1750-1326-4-48.

31.

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life.

Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM.

Neurobiol Dis. 2009 Nov;36(2):293-302. doi: 10.1016/j.nbd.2009.07.021. Epub 2009 Aug 4.

32.

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake.

Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D.

Neuron. 2009 Jun 25;62(6):788-801. doi: 10.1016/j.neuron.2009.05.012.

33.

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22.

34.

Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases.

Irvine GB, El-Agnaf OM, Shankar GM, Walsh DM.

Mol Med. 2008 Jul-Aug;14(7-8):451-64. doi: 10.2119/2007-00100.Irvine. Review.

35.

Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.

Farris W, Schütz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ.

Am J Pathol. 2007 Jul;171(1):241-51.

36.

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.

Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL.

J Neurosci. 2007 Mar 14;27(11):2866-75.

37.

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ.

J Physiol. 2006 Apr 15;572(Pt 2):477-92. Epub 2006 Feb 9.

38.

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1087-90. Review.

PMID:
16246051
39.

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ.

Nat Med. 2005 May;11(5):556-61. Epub 2005 Apr 17.

PMID:
15834427
40.

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, El Agnaf O, Hartley DM, Selkoe DJ.

J Neurosci. 2005 Mar 9;25(10):2455-62. Erratum in: J Neurosci. 2005 May 4;25(18):4658.

41.

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function.

Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, Ashe KH.

Nat Neurosci. 2005 Jan;8(1):79-84. Epub 2004 Dec 19.

PMID:
15608634

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